Previous Issue: New Series, Vol. 278, No. 5346, Dec. 19, 1997
Next Issue: New Series, Vol. 279, No. 5348, Jan. 9, 1998

Front Matter (12 pp.)
Editorial: Opening Science's Compass, p. 10
Floyd E. Bloom

Letters

The HUGO Mutation Database Initiative, pp. 10-11
R. G. H. Cotton; V. McKusick; C. R. Scriver

Sex Offenders, pp. 11-12
Susan L. McElroy; Harrison G. Pope Jr.; Abraham L. Halpern; Barbara E. O'Connell; Howard Zonana

Cancer Therapy and Tumor Physiology, pp. 12-13
Amato J. Giaccia; J. Martin Brown; Bradley Wouters; Nicholas Denko; Constantinos Koumenis

Pyramid Scheme?, p. 13
Jonathan Gallant

NASA's SkyView, p. 13
Thomas McGlynn

Genetic Diversity Survey, p. 14
William J. Schull

SIV Vaccine for AIDS, pp. 14-15
Charles F. Farthing; John L. Sullivan

Chick Heart, Not Lizard Lung, p. 15
John A. Ruben; Terry D. Jones; Nicholas R. Geist; W. Jaap Hillenius

ScienceScope, p. 19
Jocelyn Kaiser

News and Comment

Planning a Future Without ITER, pp. 20-21
James Glanz; Andrew Lawler

NIH Settles, NSF Sued in Student Cases, p. 22
Jeffrey Mervis

Astrophysicist Dies in Plane Crash, p. 22
David Ehrenstein

Physicists Urge Technology Push to Reach 2005 Target, p. 23
Eliot Marshall

5-Year Plan Boosts Basic Research, p. 24
Michael Baker

CERN Picks Maiani to Build the LHC, p. 24
Alexander Hellemans

Genome of TB Culprit Deciphered, p. 25
Nigel Williams

Kennewick Man: More Bones to Pick, pp. 25-26
Virginia Morell

Midlife Crisis Threatens Center for Semiarid Crops, pp. 26-27
Pallava Bagla

Research News

Calibrating the Mitochondrial Clock, pp. 28-29
Ann Gibbons

Geophysicists Ponder Hints of Otherworldly Water, pp. 30-31
Richard A. Kerr

Sieving Prime Numbers from Thin Ore, p. 31
Barry Cipra

New Nonopioid Painkiller Shows Promise in Animal Tests, pp. 32-33
Evelyn Strauss

Putting the Infrared Heat on X-rays, p. 33
Robert F. Service

Do Fateful Circles of DNA Cause Cells to Grow Old?, p. 34
Elizabeth Pennisi

Random Samples, p. 35
Constance Holden

Science's Compass

Policy

An Independent Perspective on the Human Genome Project, pp. 36-37
Steven E. Koonin

Books

Taxonomy Recapitulates Society, p. 38
The Platypus and the Mermaid and Other Figments of the Classifying Imagination
Harriet Ritvo

Review author[s]: Sherrie Lyons

Research

Is the Geometry of Nature Fractal?, pp. 39-40
David Avnir; Ofer Biham; Daniel Lidar; Ofer Malcai

Even Viruses Can Learn to Cope with Stress, pp. 40-41
Grant McFadden

Sweeping the Field, p. 41
David Voss

BSE and Prions: Uncertainties About the Agent, pp. 42-43
Bruce Chesebro

Webwatch, p. 43
David Voss

Science's Compass

Review

Spin-Transition Polymers: From Molecular Materials Toward Memory Devices, pp. 44-48
O. Kahn; C. Jay Martinez

Research Article

Hydrogen Radicals, Nitrogen Radicals, and the Production of O₃ in the Upper Troposphere, pp. 49-53
P. O. Wennberg; T. F. Hanisco; L. Jaeglé; D. J. Jacob; E. J. Hintsa; E. J. Lanzendorf; J. G. Anderson; R.-S. Gao; E. R. Keim; S. G. Donnelly; L. A. Del Negro; D. W. Fahey; S. A. McKeen; R. J. Salawitch; C. R. Webster; R. D. May; R. L. Herman; M. H. Proffitt; J. J. Margitan; E. L. Atlas; S. M. Schauffler; F. Flocke; C. T. McElroy; T. P. Bui

Reports

Infrared Photorefractive Polymers and Their Applications for Imaging, pp. 54-57
B. Kippelen; S. R. Marder; E. Hendrickx; J. L. Maldonado; G. Guillemet; B. L. Volodin; D. D. Steele; Y. Enami; Sandalphon; Y. J. Yao; J. F. Wang; H. Röckel; L. Erskine; N. Peyghambarian

Electromechanical Properties of an Ultrathin Layer of Directionally Aligned Helical Polypeptides, pp. 57-60
T. Jaworek; D. Neher; G. Wegner; R. H. Wieringa; A. J. Schouten

Coupling of South American and African Plate Motion and Plate Deformation, pp. 60-63
Paul G. Silver; Raymond M. Russo; Carolina Lithgow-Bertelloni

Footwall Refrigeration Along a Detachment Fault: Implications for the Thermal Evolution of Core Complexes, pp. 63-66
Jean Morrison; J. Lawford Anderson

Suppression of Volcanism During Rapid Extension in the Basin and Range Province, United States, pp. 66-68
P. B. Gans; W. A. Bohrson

Migrating Planets, pp. 69-72
N. Murray; B. Hansen; M. Holman; S. Tremaine

Magnetic Properties of Hexagonal Closed-Packed Iron Deduced from Direct Observations in a Diamond Anvil Cell, pp. 72-74
Stuart Gilder; Jonathan Glen

Formation of Molecular Chlorine from the Photolysis of Ozone and Aqueous Sea-Salt Particles, pp. 74-77
K. W. Oum; M. J. Lakin; D. O. DeHaan; T. Brauers; B. J. Finlayson-Pitts

Broad-Spectrum, Non-Opioid Analgesic Activity by Selective Modulation of Neuronal Nicotinic Acetylcholine Receptors, pp. 77-81
A. W. Bannon; M. W. Decker; M. W. Holladay; P. Curzon; D. Donnelly-Roberts; P. S. Puttfarcken; R. S. Bitner; A. Diaz; A. H. Dickenson; R. D. Porsolt; M. Williams; S. P. Arneric

Inhibition of the Hammerhead Ribozyme Cleavage Reaction by Site-Specific Binding of Tb(III), pp. 81-84
Andrew L. Feig; William G. Scott; Olke C. Uhlenbeck

Quantitation of Transcription and Clonal Selection of Single Living Cells with β-Lactamase as Reporter, pp. 84-88
Gregor Zlokarnik; Paul A. Negulescu; Thomas E. Knapp; Lora Mere; Neal Burres; Luxin Feng; Michael Whitney; Klaus Roemer; Roger Y. Tsien

Dimerization-Induced Inhibition of Receptor Protein Tyrosine Phosphatase Function Through an Inhibitory Wedge, pp. 88-91
Ravindra Majeti; Alexandrine M. Bilwes; Joseph P. Noel; Tony Hunter; Arthur Weiss

Dissociated Pattern of Activity in Visual Cortices and Their Projections During Human Rapid Eye Movement Sleep, pp. 91-95
Allen R. Braun; Thomas J. Balkin; Nancy J. Wesensten; Fuad Gwadry; Richard E. Carson; Mary Varga; Paul Baldwin; Gregory Belenky; Peter Herscovitch

Discrete Start Sites for DNA Synthesis in the Yeast ARS1 Origin, pp. 95-98
Anja-Katrin Bielinsky; Susan A. Gerbi

Modification of the NADH of the Isoniazid Target (InhA) from Mycobacterium tuberculosis, pp. 98-102
Denise A. Rozwarski; Gregory A. Grant; Derek H. R. Barton; William R. Jacobs Jr.; James C. Sacchettini

Ultraviolet-Induced Cell Death Blocked by a Selenoprotein from a Human Dermatotropic Poxvirus, pp. 102-105
Joanna L. Shisler; Tatiana G. Senkevich; Marla J. Berry; Bernard Moss

Change in Chemoattractant Responsiveness of Developing Axons at an Intermediate Target, pp. 105-107
Ryuichi Shirasaki; Ryuta Katsumata; Fujio Murakami

Back Matter (33 pp.)

Previous Issue: New Series, Vol. 278, No. 5346, Dec. 19, 1997
Next Issue: New Series, Vol. 279, No. 5348, Jan. 9, 1998

Previous Issue: New Series, Vol. 279, No. 5347, Jan. 2, 1998
Next Issue: New Series, Vol. 279, No. 5349, Jan. 16, 1998

Front Matter (22 pp.)
Editorial: Bioethics and Local Circumstances, p. 155
Edward Mbidde

Letters

EMBL's Outward Expansion, pp. 155+157
Julio E. Celis

Gene Technology and Democracy, p. 157
Franco Cavalli; Howard Olson

FDA "Reform"?, pp. 157-159
Stephen M. Feinstone; Andrew M. Lewis Jr.; Lewis J. Markoff; Kathryn Carbone; Hana Golding; Henry I. Miller

Thumbs Down on Acupuncture, p. 159
Arthur Taub

Drug Abuse and Therapy, pp. 159-161
Brian A. McMillen; Charles P. O'Brien

Ancient Sharks and Rays, p. 161
J. Mark Erickson; John W. Hoganson; Alan M. Cvancara; F. D. Holland Jr.

Corrections and Clarifications: Conversation with the Community: AAAS at the Milennium, p. 161
ScienceScope, p. 165
Andrew Lawler

News

Healer Needed for World Health Body, pp. 166-169
Michael Balter

Hunting Down the Last of the Poliovirus, p. 168
Lisa Schlein

Physicists Dream of a Muon Shot, pp. 169-170
Alexander Hellemans

Far-Off Planet Makes a Comeback, p. 170
James Glanz

Gene-War Veteran Seeks New Roles for Granting Agency, p. 171
Robert Koenig

Management Dispute Shutters Tropical Research Institute, pp. 172-173
Jeffrey Mervis

Bill Offers Abundant Harvest for USDA, p. 173
Jocelyn Kaiser

Possible New Cause of Alzheimer's Disease Found, p. 174
Gretchen Vogel

Pathfinder Tells a Geologic Tale With One Starring Role, p. 175
Richard A. Kerr

Structure of Key Cytoskeletal Protein Tubulin Revealed, pp. 176-177
Elizabeth Pennisi

Immortality Gene Discovered, p. 177
David Ehrenstein

Special News Report

Scientists Who Fund Themselves, pp. 178-181
Jon Cohen

Random Samples, p. 183
Constance Holden

Science's Compass

Policy

The Highest Attainable Standard: Ethical Issues in AIDS Vaccines, pp. 186-188
Barry R. Bloom

Books

Thawing Science, p. 189
Review author[s]: Alexei Kojevnikov

Research

Self-Trapping of Electrons at Surfaces, pp. 190-191
Ulrich Höfer

Calcium Signaling: Up, Down, Up, Down.... What's the Point?, pp. 191-192
James W. Putney Jr.

Opening the Window to Odor Space, p. 193
Randall R. Reed

Review

Activation of Unimolecular Reactions by Ambient Blackbody Radiation, pp. 194-197
R. C. Dunbar; T. B. McMahon

Reports

Engineering Broader Specificity into an Antibiotic-Producing Polyketide Synthase, pp. 199-202
Andrew F. A. Marsden; Barrie Wilkinson; Jesús Cortés; Nicholas J. Dunster; James Staunton; Peter F. Leadlay

Femtosecond Dynamics of Electron Localization at Interfaces, pp. 202-205
N.-H. Ge; C. M. Wong; R. L. Lingle Jr.; J. D. McNeill; K. J. Gaffney; C. B. Harris

Photonic Channels for Quantum Communication, pp. 205-208
S. J. van Enk; J. I. Cirac; P. Zoller

A Laser Ablation Method for the Synthesis of Crystalline Semiconductor Nanowires, pp. 208-211
Alfredo M. Morales; Charles M. Lieber

Evidence for New Sources of NO_x in the Lower Atmosphere, pp. 211-213
Edward C. Zipf; Sheo S. Prasad

Sensitivity of Boreal Forest Carbon Balance to Soil Thaw, pp. 214-217
M. L. Goulden; S. C. Wofsy; J. W. Harden; S. E. Trumbore; P. M. Crill; S. T. Gower; T. Fries; B. C. Daube; S.-M. Fan; D. J. Sutton; A. Bazzaz; J. W. Munger

Evidence of Shallow Fault Zone Strengthening After the 1992 M7.5 Landers, California, Earthquake, pp. 217-219
Yong-Gang Li; John E. Vidale; Keiiti Aki; Fei Xu; Thomas Burdette

Asymmetry of Chimpanzee Planum Temporale: Humanlike Pattern of Wernicke's Brain Language Area Homolog, pp. 220-222
Patrick J. Gannon; Ralph L. Holloway; Douglas C. Broadfield; Allen R. Braun

Stabilization of Dendritic Arbor Structure in Vivo by CaMKII, pp. 222-226
Gang-Yi Wu; Hollis T. Cline

Sensitivity of CaM Kinase II to the Frequency of Ca ²⁺ Oscillations, pp. 227-230
Paul De Koninck; Howard Schulman

Requirement for DCP-1 Caspase During Drosophila Oogenesis, pp. 230-234
Kimberly McCall; Hermann Steller

Activation of the Cardiac Calcium Release Channel (Ryanodine Receptor) by Poly-S-Nitrosylation, pp. 234-237
Le Xu; Jerry P. Eu; Gerhard Meissner; Jonathan S. Stamler

Functional Expression of a Mammalian Odorant Receptor, pp. 237-242
Haiqing Zhao; Lidija Ivic; Joji M. Otaki; Mitsuhiro Hashimoto; Katsuhiro Mikoshiba; Stuart Firestein

Frameshift Mutants of β Amyloid Precursor Protein and Ubiquitin-B in Alzheimer's and Down Patients, pp. 242-247
Fred W. van Leeuwen; Dominique P. V. de Kleijn; Helma H. van den Hurk; Andrea Neubauer; Marc A. F. Sonnemans; Jacqueline A. Sluijs; Soner Köycü; Ravindra D. J. Ramdjielal; Ahmad Salehi; Gerard J. M. Martens; Frank G. Grosveld; J. Peter H. Burbach; Elly M. Hol

Back Matter (41 pp.)

Previous Issue: New Series, Vol. 279, No. 5347, Jan. 2, 1998
Next Issue: New Series, Vol. 279, No. 5349, Jan. 16, 1998

Previous Issue: New Series, Vol. 279, No. 5348, Jan. 9, 1998
Next Issue: New Series, Vol. 279, No. 5350, Jan. 23, 1998

Front Matter (17 pp.)
Editorial: The Future of U.S. Science Policy, p. 302
Vernon J. Ehlers

Letters

Wheat Domestication, pp. 302-304
Martin K. Jones; Robin G. Allaby; Terence A. Brown; Frank Hole; Manfred Heun; Basilio Borghi; F. Salamini

Aging and Endocrinology, pp. 304-306
Ronald Ross Watson; Allan Mazur; Steven W. J. Lamberts

Immediate Release of Crystallographic Data: A Proposal, pp. 306-307
Alexander Wlodawer; David Davies; Gregory Petsko; Michael Rossmann; Arthur Olson; Joel L. Sussman

Synchrotron Collaboration, p. 307
Grant Bunker

ScienceScope, p. 311
Eliot Marshall

News and Comment

Has French AIDS Research Stumbled?, pp. 312-314
Michael Balter

Cloning Plan Spawns Ethics Debate, p. 315
David Kestenbaum

The Hottest Year, by a Hair, pp. 315-316
Richard A. Kerr

Europe Forges a Plan in Collaboration with Industry, pp. 316-317
Helen Gavaghan

Biotech Firm in High-Nicotine Intrigue, p. 317
Eliot Marshall

AXAF Delay Threatens Station, Hubble, p. 318
Andrew Lawler

Goldin May Cancel NASA Earth Probe, p. 318
Andrew Lawler

Research News

Teaching the Spinal Cord to Walk, pp. 319-321
Ingrid Wickelgren

Intruder in a Star's Dust Glimpsed, p. 322
Robert Irion

Hubble Sees All the Light There Is, p. 322
Robert Irion

Peptide-Guided Cancer Drugs Show Promise in Mice, pp. 323-324
Marcia Barinaga

Sequence Offers Clues to Deadly Flu, p. 324
Gretchen Vogel

Sea-Floor Dust Shows Drought Felled Akkadian Empire, pp. 325-326
Richard A. Kerr

Getting a 3D View of Surfaces, pp. 326-327
Gary Taubes

Chemokine Mutation Slows Progression, p. 327
Michael Balter

Random Samples, p. 329
Constance Holden

Science's Compass

Policy

The Kyoto Negotiations on Climate Change: A Science Perspective, pp. 330-331
Bert Bolin

Books

Where Sea Meets Sky, p. 332
The Sea Surface and Global Change.
Peter S. Liss; Robert A. Duce

Review author[s]: Rik Wanninkhof

Research

Tweaking the Human Circadian Clock with Ligh, pp. 333-334
Dan A. Oren; Michael Terman

Telomeres and Senescence: Ending the Debate, pp. 334-335
Titia de Lange

A New Opportunity in Silicon-Based Microelectronics, pp. 335-336
John T. Yates Jr.

Reprolysins and Astacins...Alive, Alive-O, pp. 336-337
Gerry Weinmaster

Review

Memory Suppressor Genes: Inhibitory Constraints on the Storage of Long-Term Memory, pp. 338-341
Ted Abel; Kelsey C. Martin; Dusan Bartsch; Eric R. Kandel

Research Articles

Resilient Quantum Computation, pp. 342-345
Emanuel Knill; Raymond Laflamme; Wojciech H. Zurek

Absence of a Spin Gap in the Superconducting Ladder Compound Sr₂Ca ₁₂ Cu ₂₄ O ₄₁, pp. 345-348
H. Mayaffre; P. Auban-Senzier; M. Nardone; D. Jérome; D. Poilblanc; C. Bourbonnais; U. Ammerahl; G. Dhalenne; A. Revcolevschi

Extension of Life-Span by Introduction of Telomerase into Normal Human Cells, pp. 349-352
Andrea G. Bodnar; Michel Ouellette; Maria Frolkis; Shawn E. Holt; Choy-Pik Chiu; Gregg B. Morin; Calvin B. Harley; Jerry W. Shay; Serge Lichsteiner; Woodring E. Wright

Reports

Shape Transition of Germanium Nanocrystals on a Silicon (001) Surface from Pyramids to Domes, pp. 353-355
Gilberto Medeiros-Ribeiro; Alexander M. Bratkovski; Theodore I. Kamins; Douglas A. A. Ohlberg; R. Stanley Williams

Accurate Experimental Electronic Properties of DL-Proline Monohydrate Obtained Within 1 Day, pp. 356-358
T. Koritsánszky; R. Flaig; D. Zobel; H.-G. Krane; W. Morgenroth; P. Luger

Space Geodetic Observations of Nazca-South America Convergence Across the Central Andes, pp. 358-362
Edmundo Norabuena; Lisa Leffler-Griffin; Ailin Mao; Timothy Dixon; Seth Stein; I. Selwyn Sacks; Leonidas Ocola; Michael Ellis

A Search for Endogenous Amino Acids in Martian Meteorite ALH84001, pp. 362-365
Jeffrey L. Bada; Daniel P. Glavin; Gene D. McDonald; Luann Becker

Isotopic Evidence for a Terrestrial Source of Organic Compounds Found in Martian Meteorites Allan Hills 84001 and Elephant Moraine 79001, pp. 366-369
A. J. T. Jull; C. Courtney; D. A. Jeffrey; J. W. Beck

Import of Mitochondrial Carriers Mediated by Essential Proteins of the Intermembrane Space, pp. 369-373
Carla M. Koehler; Ernst Jarosch; Kostas Tokatlidis; Karl Schmid; Rudolf J. Schweyen; Gottfried Schatz

Helicobacter pylori Adhesin Binding Fucosylated Histo-Blood Group Antigens Revealed by Retagging, pp. 373-377
Dag Ilver; Anna Arnqvist; Johan Ögren; Inga-Maria Frick; Dangeruta Kersulyte; Engin T. Incecik; Douglas E. Berg; Antonello Covacci; Lars Engstrand; Thomas Borén

Cancer Treatment by Targeted Drug Delivery to Tumor Vasculature in a Mouse Model, pp. 377-380
Wadih Arap; Renata Pasqualini; Erkki Ruoslahti

Chemokines and the Arrest of Lymphocytes Rolling Under Flow Conditions, pp. 381-384
James J. Campbell; Joseph Hedrick; Albert Zlotnik; Michael A. Siani; Darren A. Thompson; Eugene C. Butcher

Structure of the HIV-1 Nucleocapsid Protein Bound to the SL3 ψ-RNA Recognition Element, pp. 384-388
Roberto N. de Guzman; Zheng Rong Wu; Chelsea C. Stalling; Lucia Pappalardo; Philip N. Borer; Michael F. Summers

Genetic Restriction of AIDS Pathogenesis by an SDF-1 Chemokine Gene Variant, pp. 389-393
Cheryl Winkler; William Modi; Michael W. Smith; George W. Nelson; Xueyun Wu; Mary Carrington; Michael Dean; Tasaku Honjo; Kai Tashiro; D. Yabe; Susan Buchbinder; Eric Vittinghoff; James J. Goedert; Thomas R. O'Brien; Lisa P. Jacobson; Roger Detels; Sharyne Donfield; Anne Willoughby; Edward Gomperts; David Vlahov; John Phair; Stephen J. O'Brien

Characterization of an Avian Influenza A (H5N1) Virus Isolated from a Child with a Fatal Respiratory Illness, pp. 393-396
Kanta Subbarao; Alexander Klimov; Jacqueline Katz; Helen Regnery; Wilina Lim; Henrietta Hall; Michael Perdue; David Swayne; Catherine Bender; Jing Huang; Mark Hemphill; Thomas Rowe; Michael Shaw; Xiyan Xu; Keiji Fukuda; Nancy Cox

Extraocular Circadian Phototransduction in Humans, pp. 396-399
Scott S. Campbell; Patricia J. Murphy

Postsynaptic Membrane Fusion and Long-Term Potentiation, pp. 399-403
Pierre-Marie Lledo; Xiangyang Zhang; Thomas C. Südhof; Robert C. Malenka; Roger A. Nicoll

A Potassium Channel Mutation in Neonatal Human Epilepsy, pp. 403-406
Christian Biervert; Björn C. Schroeder; Christian Kubisch; Samuel F. Berkovic; Peter Propping; Thomas J. Jentsch; Ortrud K. Steinlein

An Arabidopsis MADS Box Gene that Controls Nutrient-Induced Changes in Root Architecture, pp. 407-409
Hanma Zhang; Brian G. Forde

Tech.Sight

Fingerprinting Vortices with Smoke, pp. 410-411
Peter Gammel; David Bishop

Lactamase Live!, p. 412
Robert Sikorski; Richard Peters

Droplet Discovery, pp. 412-413
Robert Sikorski; Richard Peters

Jamming Spam, p. 413
Robert Sikorski; Richard Peters

Back Matter (31 pp.)

Previous Issue: New Series, Vol. 279, No. 5348, Jan. 9, 1998
Next Issue: New Series, Vol. 279, No. 5350, Jan. 23, 1998

Previous Issue: New Series, Vol. 279, No. 5349, Jan. 16, 1998
Next Issue: New Series, Vol. 279, No. 5351, Jan. 30, 1998

Front Matter (23 pp.)
Editorial: Cell Biology of the Cytoskeleton, p. 459
Stella M. Hurtley

Letters

Mercury in Fish, pp. 459+461
Tom Clarkson; Christopher Cox; Philip W. Davidson; Gary J. Myers; Tomohiro Kawaguchi

Frog Deformities, pp. 461-462
Stanley K. Sessions

Royalties or Research Funds?, p. 462
Ernest B. Hook

Drugs for the Third World, p. 462
Sergio Erill

Nuclear Research at Duke, pp. 462-463
Werner Tornow; Ludwig DeBraeckeleer; Calvin R. Howell; N. Russell Roberson; Richard L. Walter; Henry R. Weller

Presenilin Interactions and Alzheimer's Disease, pp. 463-465
Kenneth S. Kosik; Rudolph E. Tanzi; Caleb E. Finch

ScienceScope, p. 469
Andrew Lawler

News and Comment

Green Light for Long-Awaited Facility, pp. 470-471
Andrew Lawler

An Accelerator to Boost Neutron Science, p. 471
James Glanz

'Fountain of Youth' Lifts Biotech Stock, p. 472
Robert F. Service

U.K. Cooks Up Food Standards Agency, p. 472
Nigel Williams

Medline Searches Turn Up Cases of Suspected Plagiarism, pp. 473-474
Eliot Marshall

Study Suggests New Way to Gauge Prostate Cancer Risk, p. 475
Marcia Barinaga

Bose Credited with Key Role in Marconi's Radio Breakthrough, p. 476
Jeffrey Mervis; Pallava Bagla

Research News

Cell Division Gatekeepers Identified, pp. 477-478
Elizabeth Pennisi

Did Galaxies Bloom in Clumps?, p. 479
Govert Schilling

Mimicking an Enzyme in Look and Deed, pp. 479-480
Robert F. Service

Irish Bridge Sheds Light on Dark Ages, p. 480
Sean Duke

Getting a Handle on the Molecules that Guide Axons, pp. 481-482
Evelyn Strauss

The Mediterranean Beckons to Europe's Oceanographers, pp. 483-484
Nigel Williams

The Transistor with a Heart of Gold, p. 484
Alexander Hellemans

Random Samples, pp. 485+487
Constance Holden

Association Affairs

Entering the Century of the Environment: A New Social Contract for Science, pp. 491-497
Jane Lubchenco

Science's Compass

Policy

Partnership Between South and North Crystallizes Around Malaria, pp. 498-499
Barend Mons; Eduard Klasen; Renee van Kessel; Thomas Nchinda

Books

An Architect of Science, pp. 500-501
Endless Frontier. Vannevar Bush, Engineer of the American Century.
G. Pascal Zachary

Review author[s]: William Aspray

Research

Ecological Science and Statistical Paradigms: At the Threshold, pp. 502-503
Brian A. Maurer

Direct Imaging of Adsorbates and Precursors on Surfaces, pp. 503-504
David A. King

The Coming of Age of Molecular Systematics, pp. 505-506
Laura E. Maley; Charles R. Marshall

Fixing Nitrogen Any Which Way, pp. 506-507
G. J. Leigh

Frontiers in Cell Biology: The Cytoskeleton

Rho GTPases and the Actin Cytoskeleton, pp. 509-514
Alan Hall

A Structural Scaffolding of Intermediate Filaments in Health and Disease, pp. 514-519
Elaine Fuchs; Don W. Cleveland

Kinesin and Dynein Superfamily Proteins and the Mechanism of Organelle Transport, pp. 519-526
Nobutaka Hirokawa

Unconventional Myosins in Cell Movement, Membrane Traffic, and Signal Transduction, pp. 527-533
Valerie Mermall; Penny L. Post; Mark S. Mooseker

Reports

True Polar Wander as a Mechanism for Second-Order Sea-Level Variations, pp. 534-537
Jon E. Mound; Jerry X. Mitrovica

Catalytic Galactose Oxidase Models: Biomimetic Cu(II)-Phenoxyl-Radical Reactivity, pp. 537-540
Yadong Wang; Jennifer L. DuBois; Britt Hedman; Keith O. Hodgson; T. D. P. Stack

Bimetallic System for Nitrogen Fixation: Ruthenium-Assisted Protonation of Coordinated N₂ on Tungsten with H₂, pp. 540-542
Yoshiaki Nishibayashi; Shotaro Iwai; Masanobu Hidai

Isolation of an Intrinsic Precursor to Molecular Chemisorption, pp. 542-544
David E. Brown; Douglas J. Moffatt; Robert A. Wolkow

Dangling Bond Dynamics on the Silicon (100)-2×1 Surface: Dissociation, Diffusion, and Recombination, pp. 545-548
Marcus McEllistrem; Matthew Allgeier; John J. Boland

Triblock Copolymer Syntheses of Mesoporous Silica with Periodic 50 to 300 Angstrom Pores, pp. 548-552
Dongyuan Zhao; Jianglin Feng; Qisheng Huo; Nicholas Melosh; Glenn H. Fredrickson; Bradley F. Chmelka; Galen D. Stucky

Transform-Limited, Narrow-Linewidth Lasing Action in Organic Semiconductor Microcavities, pp. 553-555
V. Bulović; V. G. Kozlov; V. B. Khalfin; S. R. Forrest

Accelerating Invasion Rate in a Highly Invaded Estuary, pp. 555-558
Andrew N. Cohen; James T. Carlton

Role of Substrates and Products of PI 3-Kinase in Regulating Activation of Rac-Related Guanosine Triphosphatases by Vav, pp. 558-560
Jaewon Han; Katherine Luby-Phelps; Balaka Das; Xiaodong Shu; Yi Xia; Raymond D. Mosteller; U. Murali Krishna; John R. Falck; Michael A. White; Daniel Broek

Coupling of Ras and Rac Guanosine Triphosphatases Through the Ras Exchanger Sos, pp. 560-563
Anjaruwee S. Nimnual; Bogdan A. Yatsula; Dafna Bar-Sagi

Plasma Insulin-Like Growth Factor-I and Prostate Cancer Risk: A Prospective Study, pp. 563-566
June M. Chan; Meir J. Stampfer; Edward Giovannucci; Peter H. Gann; Jing Ma; Peter Wilkinson; Charles H. Hennekens; Michael Pollak

The Role of Visual Experience in the Development of Columns in Cat Visual Cortex, pp. 566-570
Michael C. Crair; Deda C. Gillespie; Michael P. Stryker

Inhibitory Cerebello-Olivary Projections and Blocking Effect in Classical Conditioning, pp. 570-573
Jeansok J. Kim; David J. Krupa; Richard F. Thompson

Role of Dynamin in the Formation of Transport Vesicles from the Trans-Golgi Network, pp. 573-577
Steven M. Jones; Kathryn E. Howell; John R. Henley; Hong Cao; Mark A. McNiven

Gain-of-Function Mutations of c-kit in Human Gastrointestinal Stromal Tumors, pp. 577-580
Seiichi Hirota; Koji Isozaki; Yasuhiro Moriyama; Koji Hashimoto; Toshirou Nishida; Shingo Ishiguro; Kiyoshi Kawano; Masato Hanada; Akihiko Kurata; Masashi Takeda; Ghulam Muhammad Tunio; Yuji Matsuzawa; Yuzuru Kanakura; Yasuhisa Shinomura; Yukihiko Kitamura

Interaction of a Golgi-Associated Kinesin-Like Protein with Rab6, pp. 580-585
Arnaud Echard; Florence Jollivet; Olivier Martinez; Jean-Jacques Lacapère; Annie Rousselet; Isabelle Janoueix-Lerosey; Bruno Goud

Back Matter (35 pp.)

Previous Issue: New Series, Vol. 279, No. 5349, Jan. 16, 1998
Next Issue: New Series, Vol. 279, No. 5351, Jan. 30, 1998

Previous Issue: New Series, Vol. 279, No. 5350, Jan. 23, 1998
Next Issue: New Series, Vol. 279, No. 5352, Feb. 6, 1998

Front Matter (27 pp.)
Editorial: Bioethics and Biological Weapons, p. 635
Raymond A. Zilinskas

Letters

Dolly Confirmation, pp. 635+637-638
Vittorio Sgaramella; Norton D. Zinder; Keith H. S. Campbell; Alan Colman; Ian Wilmut

Reactor Startup, pp. 638-639
John Stringer; Andrew Lawler

Methylmercury Risks, pp. 639-641
Pál Weihe; Philippe Grandjean; Lynn R. Goldman; William H. Farland; Grace M. Egeland; John P. Middaugh

ScienceScope, p. 645
Jocelyn Kaiser

News

After Dolly, a Pharming Frenzy, pp. 646-648
Elizabeth Pennisi

No Moratorium on Clinical Trials, p. 648
Gretchen Vogel

Reform Shatters 'Iron Rice Bowl', p. 649
Li Hui

Partners Will Rethink Fusion Project, p. 649
Andrew Lawler

Impending AIDS Vaccine Trial Opens Old Wounds, p. 650
Michael Balter

Exploding Stars Point to a Universal Repulsive Force, pp. 651-652
James Glanz

Comet Shower Hit, but Life Didn't Blink, p. 652
Richard A. Kerr

New Finds Explode Old Views of the American Southwest, pp. 653-654
Mark Muro

Special News Report: Science in Antarctica

Stargazing from the End of the Earth, pp. 655-657
Richard Stone

First Glimpse at Hidden Life of Seals, p. 657
Richard Stone

Russian Outpost Readies for Otherworldly Quest, pp. 658-661
Richard Stone

Random Samples, p. 663
Constance Holden

Science's Compass

Policy

A Road Map for U.S. Carbon Reductions, pp. 669-670
Joseph Romm; Mark Levine; Marilyn Brown; Eric Petersen

Books

Extraterrestrial Tales, p. 671
UFO Crash at Roswell. The Genesis of a Modern Myth.
Benson Saler; Charles A. Ziegler; Charles B. Moore

Review author[s]: William Sims Bainbridge

Research

A Recipe for Cellulose, pp. 672-673
Nicholas Carpita; Claudia Vergara

Lipid-Regulated Kinases: Some Common Themes at Last, pp. 673-674
Julian Downward

Sparse Crystals, pp. 675-676
John Schiffer

What the Wild Things Are, pp. 676-677
James H. Buckley

Reports

Interband Electronic Excitation-Assisted Atomic-Scale Restructuring of Metal Surfaces by Nanosecond Pulsed Laser Light, pp. 679-681
Hans-Joachim Ernst; Fabrice Charra; Ludovic Douillard

The Origin of Chondrules at Jovian Resonances, pp. 681-684
S. J. Weidenschilling; F. Marzari; L. L. Hood

Possible Production of High-Energy Gamma Rays from Proton Acceleration in the Extragalactic Radio Source Markarian 501, pp. 684-686
K. Mannheim

Bragg Diffraction from Crystallized Ion Plasmas, pp. 686-689
W. M. Itano; J. J. Bollinger; J. N. Tan; B. Jelenković; X.-P. Huang; D. J. Wineland

Changes in the West Antarctic Ice Sheet Since 1963 from Declassified Satellite Photography, pp. 689-692
Robert Bindschadler; Patricia Vornberger

Penny Ice Cap Cores, Baffin Island, Canada, and the Wisconsinan Foxe Dome Connection: Two States of Hudson Bay Ice Cover, pp. 692-695
David A. Fisher; Roy M. Koerner; Jocelyne C. Bourgeois; Greg Zielinski; Cameron Wake; Claus U. Hammer; H. B. Clausen; N. Gundestrup; Sigfus Johnsen; Kumiko Goto-Azuma; Takeo Hondoh; Erik Blake; Mike Gerasimoff

Role of Vesicle-Associated Syntaxin 5 in the Assembly of Pre-Golgi Intermediates, pp. 696-700
Tony Rowe; Christiane Dascher; Sergei Bannykh; Helen Plutner; William E. Balch

Differential Use of CREB Binding Protein-Coactivator Complexes, pp. 700-703
Riki Kurokawa; Daniel Kalafus; Marie-Hélène Ogliastro; Chrissa Kioussi; Lan Xu; Joseph Torchia; Michael G. Rosenfeld; Christopher K. Glass

Transcription Factor-Specific Requirements for Coactivators and Their Acetyltransferase Functions, pp. 703-707
Edward Korzus; Joseph Torchia; David W. Rose; Lan Xu; Riki Kurokawa; Eileen M. McInerney; Tina-Marie Mullen; Christopher K. Glass; Michael G. Rosenfeld

Phosphorylation and Activation of p70 ^s6k by PDK1, pp. 707-710
Nicholas Pullen; Patrick B. Dennis; Mirjana Andjelkovic; Almut Dufner; Sara C. Kozma; Brian A. Hemmings; George Thomas

Protein Kinase B Kinases that Mediate Phosphatidylinositol 3,4,5-Trisphosphate-Dependent Activation of Protein Kinase B, pp. 710-714
Len Stephens; Karen Anderson; David Stokoe; Hediye Erdjument-Bromage; Gavin F. Painter; Andrew B. Holmes; Piers R. J. Gaffney; Colin B. Reese; Frank McCormick; Paul Tempst; J. Coadwell; Phillip T. Hawkins

Role of Ceruloplasmin in Cellular Iron Uptake, pp. 714-717
Chinmay K. Mukhopadhyay; Zouhair K. Attieh; Paul L. Fox

Molecular Analysis of Cellulose Biosynthesis in Arabidopsis, pp. 717-720
Tony Arioli; Liangcai Peng; Andreas S. Betzner; Joanne Burn; Werner Wittke; Werner Herth; Christine Camilleri; Herman Höfte; Jacek Plazinski; Rosemary Birch; Ann Cork; Julie Glover; John Redmond; Richard E. Williamson

Alopecia Universalis Associated with a Mutation in the Human Hairless Gene, pp. 720-724
Wasim Ahmad; Muhammad Faiyaz ul Haque; Valeria Brancolini; Hui C. Tsou; Sayed ul Haque; HaMut Lam; Vincent M. Aita; Jason Owen; Michelle deBlaquiere; Jorge Frank; Peter B. Cserhalmi-Friedman; Andrew Leask; John A. McGrath; Monica Peacocke; Mahmud Ahmad; Jurg Ott; Angela M. Christiano

AAAS News and Notes, p. 727
S. L. Byrand

Back Matter (41 pp.)

Previous Issue: New Series, Vol. 279, No. 5350, Jan. 23, 1998
Next Issue: New Series, Vol. 279, No. 5352, Feb. 6, 1998

Previous Issue: New Series, Vol. 279, No. 5351, Jan. 30, 1998
Next Issue: New Series, Vol. 279, No. 5353, Feb. 13, 1998

Front Matter (23 pp.)
Editorial: In Celebration of AAAS, p. 783
Richard B. Gallagher; Christine Gilbert; Barbara Jasny; Andrew Lawler; Elizabeth Pennisi; Linda R. Rowan; Julia Uppenbrink

Letters

Is Nature Fractal?, pp. 783+785-786
Benoit B. Mandelbrot; Peter Pfeifer; Ofer Biham; Ofer Malcai; Daniel A. Lidar; David Avnir

Muon Collider, pp. 786-787
Andrew M. Sessler

Insulin/IGF Signaling and HNF-3/forkhead Proteins, pp. 787-788
Terry G. Unterman; Kui Lin; Cynthia Kenyon

Ending Polio Immunization, pp. 788-789
Tjeerd G. Kimman; Marion P. G. Koopmans; Harrie G. A. M. van der Avoort; Alan W. Dove; Vincent R. Racaniello; Harry F. Hull; R. Bruce Aylward

ScienceScope, p. 793
Jocelyn Kaiser

News and Comment

Science Catches Clinton's Eye, pp. 794-797
Andrew Lawler

A New Link between Tobacco and Cancer, p. 796
Eliot Marshall

Census 2000: Where Science and Politics Count Equally, pp. 798-799
David Kestenbaum

Blasting Tumors with Particle Beams, p. 799
Nigel Williams

Atlantic Salmon Spawn Fight Over Species Protection, p. 800
David Malakoff

Virus from 1959 Sample Marks Early Years of HIV, p. 801
Michael Balter

Korea Makes a Bid to Catch Neutrinos from the Cosmos, p. 802
Dennis Normile

Research News

Pushing Back the Origins of Animals, pp. 803-804
Richard A. Kerr

Proving a Link between Logic and Origami, pp. 804-805
Barry Cipra

A Deep Root for Iceland?, p. 806
Richard A. Kerr

That Winking, Blinking Sun, p. 806
Andrew Watson

Coral Reefs Dominate Integrative Biology Meeting, pp. 807-809
Elizabeth Pennisi

Overfishing Disrupts Entire Ecosystems, p. 809
Nigel Williams

Random Samples, p. 811
Constance Holden

Essays on Science and Society

The Great Asymmetry, pp. 812-813
Stephen Jay Gould

Science's Compass

Policy

Badgers and Bovine TB: Conflicts between Conservation and Health, pp. 817-818
J. R. Krebs; R. M. Anderson; T. Clutton-Brock; C. A. Donnelly; S. Frost; W. I. Morrison; R. Woodroffe; D. Young

Books

A View from the Other Side, p. 819
Toward the End of Time.
John Updike

Review author[s]: Richard C. Adelman

Research

Selective Chemistry Redux, pp. 820-821
Izhack Oref

Reversal of the Burden of Proof in Fisheries Management, pp. 821-822
Paul K. Dayton

Kenichi Fukui (1918-1998), p. 822
Kimihiko Hirao

Searching for a Partner, pp. 823-824
James E. Haber

Sliding Skis and Slipping Faults, pp. 824-825
Douglas A. Wiens

Webwatch, p. 825
David Voss

Research Article

A Transmembrane Form of the Prion Protein in Neurodegenerative Disease, pp. 827-834
Ramanujan S. Hegde; James A. Mastrianni; Michael R. Scott; Kathryn A. DeFea; Patrick Tremblay; Marilyn Torchia; Stephen J. DeArmond; Stanley B. Prusiner; Vishwanath R. Lingappa

Reports

Incorporation of Photoluminescent Polarizers into Liquid Crystal Displays, pp. 835-837
Christoph Weder; Christian Sarwa; Andrea Montali; Cees Bastiaansen; Paul Smith

A Rare-Earth Phosphor Containing One-Dimensional Chains Identified Through Combinatorial Methods, pp. 837-839
Earl Danielson; Martin Devenney; Daniel M. Giaquinta; Josh H. Golden; Robert C. Haushalter; Eric W. McFarland; Damodara M. Poojary; Casper M. Reaves; W. Henry Weinberg; Xin Di Wu

Frictional Melting During the Rupture of the 1994 Bolivian Earthquake, pp. 839-842
Hiroo Kanamori; Don L. Anderson; Thomas H. Heaton

A Determination of the HDO/H₂O Ratio in Comet C/1995 O1 (Hale-Bopp), pp. 842-844
Roland Meier; Tobias C. Owen; Henry E. Matthews; David C. Jewitt; Dominique Bockelée-Morvan; Nicolas Biver; Jacques Crovisier; Daniel Gautier

Water in Betelgeuse and Antares, pp. 844-847
Donald E. Jennings; Pedro V. Sada

Femtosecond Activation of Reactions and the Concept of Nonergodic Molecules, pp. 847-851
Eric W.-G. Diau; Jennifer L. Herek; Zee Hwan Kim; Ahmed H. Zewail

Fluorescent, Sequence-Selective Peptide Detection by Synthetic Small Molecules, pp. 851-853
Chao-Tsen Chen; Holger Wagner; W. Clark Still

Expansion and Length-Dependent Fragility of CTG Repeats in Yeast, pp. 853-856
Catherine H. Freudenreich; Sara M. Kantrow; Virginia A. Zakian

A Spliceosomal Recycling Factor that Reanneals U4 and U6 Small Nuclear Ribonucleoprotein Particles, pp. 857-860
Pratima L. Raghunathan; Christine Guthrie

Fishing Down Marine Food Webs, pp. 860-863
Daniel Pauly; Villy Christensen; Johanne Dalsgaard; Rainer Froese; Francisco Torres Jr.

Impaired Locomotion and Dopamine Signaling in Retinoid Receptor Mutant Mice, pp. 863-867
Wojciech Krȩżel; Norbert Ghyselinck; Tarek A. Samad; Valérie Dupé; Philippe Kastner; Emiliana Borrelli; Pierre Chambon

Abnormal Hippocampal Spatial Representations in aCaMKII ^T286A and CREB ^αΔ- Mice, pp. 867-869
Yoon H. Cho; Karl P. Giese; Heikki Tanila; Alcino J. Silva; Howard Eichenbaum

Autophosphorylation at Thr ²⁸⁶ of the a Calcium-Calmodulin Kinase II in LTP and Learning, pp. 870-873
Karl Peter Giese; Nikolai B. Fedorov; Robert K. Filipkowski; Alcino J. Silva

Conjugative Transfer by the Virulence System of Legionella pneumophila, pp. 873-876
Joseph P. Vogel; Helene L. Andrews; Swee Kee Wong; Ralph R. Isberg

Meiotic Synapsis in the Absence of Recombination, pp. 876-878
Kim S. McKim; Becky L. Green-Marroquin; Jeff J. Sekelsky; Gregory Chin; Carrie Steinberg; Rita Khodosh; R. Scott Hawley

Precambrian Sponges with Cellular Structures, pp. 879-882
Chia-Wei Li; Jun-Yuan Chen; Tzu-En Hua

Back Matter (66 pp.)

Previous Issue: New Series, Vol. 279, No. 5351, Jan. 30, 1998
Next Issue: New Series, Vol. 279, No. 5353, Feb. 13, 1998

Previous Issue: New Series, Vol. 279, No. 5352, Feb. 6, 1998
Next Issue: New Series, Vol. 279, No. 5354, Feb. 20, 1998

Front Matter (21 pp.)
Editorial: The Budget: Too Good or True?, p. 963
Floyd E. Bloom

Letters

Multilab Partnerships, pp. 963+965
Burton Richter; John J. Rush

"More of the Same" in Switzerland?, pp. 965-967
Jonathan R. Latham; Rolf Zinkernagel

MRC Commitments, pp. 967-968
George K. Radda; Stephen C. Harvey

Climate Change and Human Health, pp. 968-969
Rita R. Colwell; Paul R. Epstein; Duane Gubler; Nancy Maynard; Anthony J. McMichael; Jonathan A. Patz; R. Brad Sack; Robert Shope

Heisenberg Meets Photobiology?, p. 969
Dan A. Oren; Steve A. Kay

Corrections and Clarifications: The HUGO Mutation Database Initiative, p. 969
Corrections and Clarifications: The Spatial Dimension in Population Functions, p. 969
Corrections and Clarifications: The Architecture of Hearing, p. 969
Corrections and Clarifications: Trace Gas Emissions and Smoke-Induced Seed Germination, p. 969
ScienceScope, p. 973
Jocelyn Kaiser

News and Comment

Science Funding: Up in Smoke?, pp. 974-975
Eliot Marshall

FDA Scientists Resist Cuts in In-House Research Positions, pp. 976-977
Bruce Agnew

Red Ink Will Not Wash Out Space Science, p. 977
Andrew Lawler

Taking a Structured Approach to Understanding Proteins, pp. 978-979
Elizabeth Pennisi

Database Funding Left Out in the Cold, pp. 979-980
Wayne Kondro

New Wetlands Proposal Draws Flak, p. 980
Jocelyn Kaiser

Research News

The Universe Shows Its Age, pp. 981-983
Andrew Watson

A Method in Ebola's Madness, pp. 983-984
Ingrid Wickelgren

Of Mice and Moths-and Lyme Disease?, pp. 984-985
Jocelyn Kaiser

A Slow Start for Earthquakes, p. 985
Richard A. Kerr

Atom Laser Shows that it is Worthy of the Name, pp. 986-987
Alexander Hellemans

Sunquakes May Power Solar Symphony, p. 987
Erik Stokstad

Global Nitrogen Overload Problem Grows Critical, pp. 988-989
Anne Simon Moffat

New Threat Seen from Carbon Dioxide, p. 989
Elizabeth Pennisi

Random Samples, p. 991
Gretchen Vogel

Essays on Science and Society

The Third Culture, pp. 992-993
K. Kelly

Science's Compass

Policy

Medical Consequences of Antibiotic Use in Agriculture, pp. 996-997
Wolfgang Witte

Books

Unraveling Complex Events, p. 998
Physics in the Nineteenth Century.
Robert D. Purrington

Review author[s]: Stephen G. Brush

Research

Mitotic Arrest: Mad2 Prevents Sleepy from Waking Up the APC, pp. 999-1000
Stephen J. Elledge

Inner Workings of a Transcription Factor Partnership, pp. 1000-1002
Barbara J. Graves

Radical Ideas, pp. 1002-1003
Dieter H. Ehhalt

Warmer and Wetter 6000 Years Ago?, pp. 1003-1004
Warren Beck

Heartthrobs, p. 1004
Dottie Hanck

Reports

Bosonic Stimulation in the Formation of a Bose-Einstein Condensate, pp. 1005-1007
H.-J. Miesner; D. M. Stamper-Kurn; M. R. Andrews; D. S. Durfee; S. Inouye; W. Ketterle

Three-Dimensional Simulations of Plume-Lithosphere Interaction at the Hawaiian Swell, pp. 1008-1011
William B. Moore; Gerald Schubert; Paul Tackley

Photometry and Spectroscopy of the GRB 970508 Optical Counterpart, pp. 1011-1014
Alberto J. Castro-Tirado; Javier Gorosabel; Narciso Benítez; Christian Wolf; Ralf Fockenbrock; Enrique Martínez-González; Helmuth Kristen; Adrick Broeils; Holger Pedersen; Jochen Greiner; Enrico Costa; Marco Feroci; Luigi Piro; Filippo Frontera; Luciano Nicastro; Eliana Palazzi; Corrado Bartolini; Adriano Guarnieri; Nicola Masetti; Adalberto Piccioni; Marco Mignoli; Magrethe Wold; Mark Lacy; Kurt Birkle; Tom Broadhurst; Søren Brandt; Niels Lund

Temperature and Surface-Ocean Water Balance of the Mid-Holocene Tropical Western Pacific, pp. 1014-1018
Michael K. Gagan; Linda K. Ayliffe; David Hopley; Joseph A. Cali; Graham E. Mortimer; John Chappell; Malcolm T. McCulloch; M. John Head

Simulated Increase of Hurricane Intensities in a CO₂-Warmed Climate, pp. 1018-1020
Thomas R. Knutson; Robert E. Tuleya; Yoshio Kurihara

Chiral Spaces: Dissymmetric Capsules Through Self-Assembly, pp. 1021-1023
José M. Rivera; Tomás Martín; Julius Rebek Jr.

Chain Reactions Linking Acorns to Gypsy Moth Outbreaks and Lyme Disease Risk, pp. 1023-1026
Clive G. Jones; Richard S. Ostfeld; Michele P. Richard; Eric M. Schauber; Jerry O. Wolff

Ca ²⁺ Flux Through Promiscuous Cardiac Na⁺ Channels: Slip-Mode Conductance, pp. 1027-1033
L. F. Santana; A. M. Gómez; W. J. Lederer

Distinct Cellular Interactions of Secreted and Transmembrane Ebola Virus Glycoproteins, pp. 1034-1037
Zhi-yong Yang; Rafael Delgado; Ling Xu; Robert F. Todd; Elizabeth G. Nabel; Anthony Sanchez; Gary J. Nabel

The Structure of GABPα/β: An ETS Domain-Ankyrin Repeat Heterodimer Bound to DNA, pp. 1037-1041
Adrian H. Batchelor; Derek E. Piper; Fabienne Charles de la Brousse; Steven L. McKnight; Cynthia Wolberger

Budding Yeast Cdc20: A Target of the Spindle Checkpoint, pp. 1041-1044
Lena H. Hwang; Lucius F. Lau; Dana L. Smith; Cathy A. Mistrot; Kevin G. Hardwick; Ellen S. Hwang; Angelika Amon; Andrew W. Murray

Fission Yeast Slp1: An Effector of the Mad2-Dependent Spindle Checkpoint, pp. 1045-1047
Sang Hoon Kim; Diana P. Lin; Sanae Matsumoto; Ana Kitazono; Tomohiro Matsumoto

Structure of the Amino-Terminal Protein Interaction Domain of STAT-4, pp. 1048-1052
Uwe Vinkemeier; Ismail Moarefi; James E. Darnell Jr.; John Kuriyan

Uncoupling of Immune Complex Formation and Kidney Damage in Autoimmune Glomerulonephritis, pp. 1052-1054
Raphael Clynes; Calin Dumitru; Jeffrey V. Ravetch

The Minor Histocompatibility Antigen HA-1: A Diallelic Gene with a Single Amino Acid Polymorphism, pp. 1054-1057
Joke M. M. den Haan; Leslie M. Meadows; Wei Wang; Jos Pool; Els Blokland; Tracie L. Bishop; Carla Reinhardus; Jeffrey Shabanowitz; Rienk Offringa; Donald F. Hunt; Victor H. Engelhard; Els Goulmy

Back Matter (39 pp.)

Previous Issue: New Series, Vol. 279, No. 5352, Feb. 6, 1998
Next Issue: New Series, Vol. 279, No. 5354, Feb. 20, 1998

Previous Issue: New Series, Vol. 279, No. 5353, Feb. 13, 1998
Next Issue: New Series, Vol. 279, No. 5355, Feb. 27, 1998

Front Matter (35 pp.)
Editorial: Catalizing Scientific Progress, p. 1111
Bill Clinton

Letters

FDA Reform: Unintended Outcome?, p. 1113
David Korn

On Their Own, pp. 1113-1114
Anne Fausto-Sterling

One Man's "Torment...", p. 1114
David Dunthorn

"Gaps" in the K-T Record, pp. 1114-1115
J. David Archibald

Human Genome Project: Data Quality, pp. 1115-1116
Phil Green; Steven E. Koonin

α-Synuclein Gene and Parkinson's Disease, pp. 1116-1117
The French Parkinson's Disease Genetics Study Group (7)

Universal Quantum Simulators: Correction, p. 1117
Seth Lloyd

ScienceScope, p. 1121
Jocelyn Kaiser

News and Comment

Clinton Names Adviser, NSF Chief, pp. 1122-1123
Andrew Lawler

Biomedical Groups Derail Fast-Track Anticloning Bill, pp. 1123-1124
Eliot Marshall

House Panel Icy to White House Plans, p. 1124
Andrew Lawler

EU Bodies on Collision Course over Research Budget, p. 1125
Nigel Williams

Max Planck at 50 Seeks to Move with the Times, p. 1126
Robert Koenig

NMR Researchers Look to the Next Generation of Machines, pp. 1127-1128
Robert F. Service

Young Physicists Despair of Tenured Jobs, p. 1128
James Glanz

Research News

The Nucleus's Revolving Door, pp. 1129-1131
Elizabeth Pennisi

Black Sea Deluge may have Helped Spread Farming, p. 1132
Richard A. Kerr

Failure Isn't What it Used to Be... But Neither is Success, pp. 1133-1134
Jon Cohen

New Appetite-Boosting Peptides Found, p. 1134
Marcia Barinaga

Self-Assembled LEDs Shine Brightly, p. 1135
Robert F. Service

Malaria Strains Appear to Gang Up Against Immune Defenses, p. 1136
Nigel Williams

Random Samples, pp. 1137+1139
Constance Holden

Essays on Science and Society

What is the Role of Science in Developing Countries?, pp. 1140-1141
José Goldemberg

Science's Compass

Policy

Containment of Antiobiotic Resistance, pp. 1153-1154
Rosamund J. Williams; David L. Heymann

Books

Many Faces of the Synapse, p. 1155
Excitatory Amino Acids and Synaptic Transmission.
H. V. Wheal; A. M. Thomson

Review author[s]: Laurence Trussell

Research

Chaos has come Again, pp. 1156-1157
Daniel J. Gauthier

Superconductivity Compatibility, pp. 1157-1158
Anthony J. Leggett

Complexity Matters, pp. 1158-1159
Günter Wagner

Fixing Mismatches, pp. 1159-1160
Michele Shannon; Martin Weigert

Research Articles

Structural Basis of Plasticity in T Cell Receptor Recognition of a Self Peptide-MHC Antigen, pp. 1166-1172
K. Christopher Garia; Massimo Degano; Larry R. Pease; Mingdong Huang; Per A. Peterson; Luc Teyton; Ian A. Wilson

Association of Malaria Parasite Population Structure, HLA, and Immunological Antagonism, pp. 1173-1177
Sarah C. Gilbert; Magdalena Plebanski; Sunetra Gupota; Joanne Morris; Martin Cox; Michael Aidoo; Dominic Kwiatkowski; Brian M. Greenwood; Hilton C. Whittle; Adrian V. S. Hill

Reports

Rare Gas Systematics in Popping Rock: Isotpic and Elemental Compositions in the Upper Mantle, pp. 1178-1181
Manuel Moreira; Joachim Kunz; Claude Allègre

The Formation of HCS and HCSH Molecules and Their Role in the Collision of Comet Shoemaker-Levy 9 with Jupiter, pp. 1181-1184
R. I. Kaiser; C. Ochsenfeld; M. Head-Gordon; Y. T. Lee

Direct Observation of Heterogeneous Chemistry in the Atmosphere, pp. 1184-1187
Eric E. Gard; Michael J. Kleeman; Deborah S. Gross; Lara S. Hughes; Jonathan O. Allen; Bradley D. Morrical; David P. Fergenson; Tas Dienes; Markus E. Gälli; Robert J. Johnson; Glen R. Cass; Kimberly A. Prather

Atmospheric Radiocarbon Calibration to 45,000 yr B. P.: Late Glacial Fluctuations and Cosmogenic Isotope Production, pp. 1187-1190
H. Kitagawa; J. van der Plicht

Probing Single Secretory Vesicles with Capillary Electrophoresis, pp. 1190-1193
Daniel T. Chiu; Sheri J. Lillard; Richard H. Scheller; Richard N. Zare; Sandra E. Rodriguez-Cruz; Evan R. Williams; Owe Orwar; Mats Sandberg; J. Anders Lundqvist

Images of Interlayer Josephson Vortices in TI₂Ba₂CuO _6+δ, pp. 1193-1196
Kathryn A. Moler; John R. Kirtley; D. G. Hinks; T. W. Li; Ming Xu

c-Axis Electrodynamics as Evidence for the Interlayer Theory of High- Temperature Superconductivity, pp. 1196-1198
Philip W. Anderson

Communication with Chaotic Lasers, pp. 1198-1200
Gregory D. VanWiggeren; Rajarshi Roy

Induced Responses to Herbivory and Increased Plant Performance, pp. 1201-1202
Anurag A. Agrawal

Regulation of Neurotransmitter Release Kinetics by NSF, pp. 1203-1206
Felix E. Schweizer; Thomas Dresbach; William M. DeBello; Vincent O'Connor; George J. Augustine; Heinrich Betz

Mismatch Repair Co-opted by Hypermutation, pp. 1207-1210
Marilia Cascalho; Jamie Wong; Charles Steinberg; Matthias Wabl

Pleiotropy and the Preservation of Perfection, pp. 1210-1213
David Waxman; Joel R. Peck

Sensorimotor Adaptation in Speech Production, pp. 1213-1216
John F. Houde; Michael I. Jordan

Mass Spectrometric Analysis of the Anaphase-Promoting Complex from Yeast: Identification of a Subunit Related to Cullins, pp. 1216-1219
Wolfgang Zachariae; Andrej Shevchenko; Paul D. Andrews; Rafael Ciosk; Marta Galova; Michael J. R. Stark; Matthias Mann; Kim Nasmyth

Identification of a Cullin Homology Region in a Subunit of the Anaphase- Promoting Complex, pp. 1219-1222
Hongtao Yu; Jan-Michael Peters; Randall W. King; Andrew M. Page; Philip Hieter; Marc W. Kirschner

Rapid Turnover of T Lymphocytes in SIV-Infected Rhesus Macaques, pp. 1223-1227
Hiroshi Mohri; Sebastian Bonhoeffer; Simon Monard; Alan S. Perelson; David D. Ho

Tech.Sight

Spectral Genotyping of Human Alleles, pp. 1228-1229
Leondios G. Kostrikis; Sanjay Tyagi; Musa M. Mhlanga; David D. Ho; Fred Russell Kramer

Mass spectroscopic Genomics, p. 1230
Richard Peters; Robert Sikorski

Molecular Plumbing, pp. 1230-1231
Richard Peters; Robert Sikorski

On the PROW, p. 1231
Richard Peters; Robert Sikorski

The X Files, p. 1231
Richard Peters; Robert Sikorski

Back Matter (37 pp.)

Previous Issue: New Series, Vol. 279, No. 5353, Feb. 13, 1998
Next Issue: New Series, Vol. 279, No. 5355, Feb. 27, 1998

Previous Issue: New Series, Vol. 279, No. 5354, Feb. 20, 1998
Next Issue: New Series, Vol. 279, No. 5356, Mar. 6, 1998

Front Matter (39 pp.)
Editorial: Better Approaches to Science Policy, p. 1283
Richard E. Sclove

Letters

Akkadian Empire: Where to Look?, pp. 1283+1285
Tony Wilkinson

Gentlemen of Science, p. 1285
Krishna R. Dronamraju

Muon Collider Studies, pp. 1285-1286
David B. Cline

Cracking the Codes, p. 1286
Alexander Fowler

Pinning Down Cell Division?, p. 1287
George L. Gabor Miklos; Steven D. Hanes; Richard Maleszka

Clinical Applications for Neural Noise?, pp. 1287-1288
Michel Le Van Quyen; Jacques Martinerie; Francisco J. Varela; William D. O'Neill

Haeckel's Embryos, p. 1288
James Hanken; Michael K. Richardson

Secretion of Thiols and Disulfide Bond Formation: Retraction, pp. 1288-1289
Roberto Sitia; Aldo Ceriotti; Andrea Cabibbo; Giorgio Fassina; Menotti Ruvo

Corrections and Clarifications: EU Bodies on Collision Course Over Research Budget, p. 1289
Corrections and Clarifications: New Developmental Clock Discovered, p. 1289
Corrections and Clarifications: The Architecture of Hearing, p. 1289
Corrections and Clarifications: Formation of a Silicate L₃ Phase with Continuously Adjustable Pore Sizes, p. 1289
ScienceScope, p. 1293
Jocelyn Kaiser

News

Microsoft Researches Its Future, pp. 1294-1296
Dana Mackenzie

Reports Call for New Super-Accelerator, pp. 1296-1297
David Kestenbaum

Northern Europe Tops in High School, p. 1297
Gretchen Vogel

Astronomers See a Cosmic Antigravity Force at Work, pp. 1298-1299
James Glanz

Controversial Trial Offers Hopeful Result, p. 1299
Eliot Marshall

Bringing Order to Amorphous Silicon, p. 1300
Robert F. Service

New NIH Grants for Clinical Research, p. 1300
Eliot Marshall

Unusual Cells May Help Treat Parkinson's Disease, p. 1301
Marcia Barinaga

Ocean Scientists Find Life, Warmth in the Seas, pp. 1302-1303
Robert Irion

Sea Floor Records Reveal Interglacial Climate Cycles, pp. 1304-1305
Richard A. Kerr

Viral Saboteurs Caught in the Act, p. 1305
Steven Dickman

AAAS Meeting, pp. 1306-1309

Random Samples, p. 1311
Constance Holden

Essays on Science and Society

Gardenification of Wildland Nature and the Human Footprint, pp. 1312-1313
Daniel Janzen

Science's Compass

Books

Quantum Physics With an Eastern Eye, p. 1319
The Story of Spin.
Sin-Itiro Tomonaga; Takeshi Oka

Review author[s]: J. D. Jackson

Recreating the Brain Online, p. 1320
Neuroinformatics. An Overview of the Human Brain Project.
Stephen H. Koslow; Michael F. Huerta

Review author[s]: Richard Frackowiak

Research

At the Border of Eternity, pp. 1321-1322
G. S. Bisnovatyi-Kogan

That Flashing Sound, pp. 1322-1323
Harold Metcalf

Plants See the Blue Light, pp. 1323-1324
Paula Suárez-López; George Coupland

After the End: Recovery from Extinction, pp. 1324-1325
Douglas H. Erwin

Reports

Geographic Variation in the Molluscan Recovery from the End-Cretaceous Extinction, pp. 1327-1330
David Jablonski

Geomagnetic Modulation of the ³⁶ CI Flux in the GRIP Ice Core, Greenland, pp. 1330-1332
S. Baumgartner; J. Beer; J. Masarik; G. Wagner; L. Meynadier; H.-A. Synal

Carbonic Acid in the Gas Phase and Its Astrophysical Relevance, pp. 1332-1335
Wolfgang Hage; Klaus R. Liedl; Andreas Hallbrucker; Erwin Mayer

Abrupt Climate Events 500,000 to 340,000 Years Ago: Evidence from Subpolar North Atlantic Sediments, pp. 1335-1338
D. W. Oppo; J. F. McManus; J. L. Cullen

Time Scales in Atmospheric Chemistry: Coupled Perturbations to N₂O, NO_y, and O₃, pp. 1339-1341
Michael J. Prather

The Role of Ocean-Atmosphere Interactions in Tropical Cooling During the Last Glacial Maximum, pp. 1341-1344
Andrew B. G. Bush; S. George H. Philander

Molecular Mimicry by Herpes Simplex Virus-Type 1: Autoimmune Disease After Viral Infection, pp. 1344-1347
Zi-Shan Zhao; Francesca Granucci; Lily Yeh; Priscilla A. Schaffer; Harvey Cantor

An Area Specialized for Spatial Working Memory in Human Frontal Cortex, pp. 1347-1351
Susan M. Courtney; Laurent Petit; José Ma. Maisog; Leslie G. Ungerleider; James V. Haxby

Propagating Activity Patterns in Large-Scale Inhibitory Neuronal Networks, pp. 1351-1355
J. Rinzel; D. Terman; X.-J. Wang; B. Ermentrout

Linkage of Adhesion, Filamentous Growth, and Virulence in Candida albicans to a Single Gene, INT1, pp. 1355-1358
Cheryl A. Gale; Catherine M. Bendel; Mark McClellan; Melinda Hauser; Jeffrey M. Becker; Judith Berman; Margaret K. Hostetter

Melatonin Production: Proteasomal Proteolysis in Serotonin N-Acetyltransferase Regulation, pp. 1358-1360
Jonathan A. Gastel; Patrick H. Roseboom; Peter A. Rinaldi; Joan L. Weller; David C. Klein

Regulation of Flowering Time by Arabidopsis Photoreceptors, pp. 1360-1363
Hongwei Guo; Hongyun Yang; Todd C. Mockler; Chentao Lin

Src Activation in the Induction of Long-Term Potentiation in CA1 Hippocampal Neurons, pp. 1363-1367
You Ming Lu; John C. Roder; Jonathan Davidow; Michael W. Salter

Target-Specific Expression of Presynaptic Mossy Fiber Plasticity, pp. 1368-1370
Gianmaria Maccaferri; Katalin Tóth; Chris J. McBain

Changes in Auxin Response from Mutations in an AUX/IAA Gene, pp. 1371-1373
Dean Rouse; Pamela Mackay; Petra Stirnberg; Mark Estelle; Ottoline Leyser

AAAS News and Notes, pp. 1388-1389
S. L. Byrand

Back Matter (27 pp.)

Previous Issue: New Series, Vol. 279, No. 5354, Feb. 20, 1998
Next Issue: New Series, Vol. 279, No. 5356, Mar. 6, 1998

Previous Issue: New Series, Vol. 279, No. 5355, Feb. 27, 1998
Next Issue: New Series, Vol. 279, No. 5357, Mar. 13, 1998

Front Matter (23 pp.)
Editorial: The Challenges Facing ASEAN Science, p. 1431
William Padolina

Letter

Sunlight and the Deep Ocean, p. 1431
Paul C. Mangelsdorf Jr.

Lost Potential in France?, pp. 1431+1433
Daniel Schlaifer; Olivier Rixe

Wheat Domestication: Archaeobotanical Evidence, p. 1433
Mark Nesbitt; Delwen Samuel

HIV Vaccine Trials, pp. 1433-1436
Don C. Des Jarlais; Suphak Vanichseni; Michael Marmor; Dwip Kitayaporn; Thea Kalebic; Edward K. Mbidde

Helper CD4⁺ T Cells and HIV-1, p. 1436
Felix Mor; Bruce D. Walker; Eric Rosenberg; Spyros Kalans

Letters

Quantal Memory Durations: Observations Not Reproduced, p. 1437
David S. Vicario; Fernando Nottebohm

ScienceScope, p. 1441
Richard Stone

News and Comment

What Ails French Biomedicine?, pp. 1442-1443
Michael Balter

Faster, Cheaper, Better is Also Harder, p. 1443
Andrew Lawler

Dutch Pull the Plug on Cow Cloning, p. 1444
Martin Enserink

Problems Plague Oak Ridge Reactor, p. 1444
Andrew Lawler

Brazil Wants Cut of Its Biological Bounty, p. 1445
Elizabeth Pennisi

Research Funding Cuts Restored, pp. 1445-1446
Wayne Kondro

Government Stalls on Dearing Challenge, p. 1446
Nigel Williams

As Mideast Peace Process Lags, Science Endures, pp. 1447-1448
Jocelyn Kaiser

Research News

Intimate Views of the Stars, pp. 1449-1451
James Glanz

Boom and Bust at R Leonis, p. 1450
Andrew Watson

Owl Study Sheds Light on How Young Brains Learn, pp. 1451-1452
Marcia Barinaga

Yemen's Stonehenge Suggests Bronze Age Red Sea Culture, pp. 1452-1453
Heather Pringle

Habitat Seen Playing Larger Role in Shaping Behavior, pp. 1454-1455
Dennis Normile

Inflation Confronts an Open Universe, p. 1455
Andrew Watson

Bone Marrow Cells may Provide Muscle Power, p. 1456
Elizabeth Pennisi

Landslide Exposes Roots of Io's Peaks, p. 1457
Robert Irion

A Dial-Up Quantum Reality, p. 1457
David kestenbaum

Random Samples, p. 1459
Constance Holden

Essays on Science and Society

The Rise of Intellectual Property Protection in the American University, pp. 1460-1461
Lita Nelsen

Science in Southeast Asia

[Introduction], p. 1465
Jeffrey D. Mervis; Dennis Normile

Scientific Growth Faces Fiscal Crisis, pp. 1466-1467
Jeffrey Mervis; Dennis Normile

Profile: Tracking a Virus and Making a Point, p. 1467
J.D.M.

Strengthening Science: First you Need Trained Scientists, pp. 1468-1470
Jeffrey Mervis; Dennis Normile

Profile: Making a Splash in Marine Science, p. 1469
D.N.

Agencies Embrace Peer Review to Strengthen Research Base, pp. 1471-1473
Jeffrey Mervis; Dennis Normile

Profile: Reviving a Nobel Past in Indonesia, p. 1471
J.D.M.

Profile: Setback Spurs a Leap Ahead, p. 1473
D.N.

University Reform Seen as Key to Improving Research, pp. 1474-1476
Jeffrey Mervis; Dennis Normile

Lopsided Partnerships Give Way to Real Collaboration, pp. 1477-1479
Jeffrey Mervis; Dennis Normile

Profile: Keeper of the Keys to Fossil Kingdom, p. 1477
J.D.M.

Profile: Reaching for the Sky to Nurture Science, p. 1479
J.D.M.

Counting on Technology for Help Up the Economic Ladder, pp. 1480-1482
Jeffrey Mervis; Dennis Normile

Profile: Shaking Up a Seismology Institute, p. 1480
D.N.

Profile: Securing a Niche for Basic Biology, p. 1482
D.N.

Science's Compass

Policy

Who Will Fuel China?, p. 1483
Thomas E. Drennen; Jon D. Erickson

Books

The Nature of Matter, p. 1484
Image and Logic. A Material Culture of Microphysics.
Peter Galison

Review author[s]: Martin L. Perl

Windows into Mathematical Minds, p. 1485
Fermat's Enigma. The Epic Quest to Solve the World's Greatest Mathematical Problem.
Simon Singh

Review author[s]: David B. Levine

Research

An RNA-Based Information Superhighway in Plants, pp. 1486-1487
Richard A. Jorgensen; Ross G. Atkinson; Richard L. S. Forster; William J. Lucas

Connecting Again with Magnetic Reconnection, pp. 1488-1489
W. M. Tang

A Dislocation Crash Test, pp. 1489-1490
Peter Gumbsch

Topological Nuts and Bolts, pp. 1490-1491
Howard A. Nash

Webwatch, p. 1491
David Voss

Geological Evolution of Venus: Rises, Plains, Plumes, and Plateaus, pp. 1492-1497
Roger J. Phillips; Vicki L. Hansen

Research Articles

Cretaceous Vertical Motion of Australia and the Australian-Antarctic Discordance, pp. 1499-1504
Michael Gurnis; R. Dietmar Müller; Louis Moresi

Crystal Structures of Human Topoisomerase I in Covalent and Noncovalent Complexes with DNA, pp. 1504-1513
Matthew R. Redinbo; Lance Stewart; Peter Kuhn; James J. Champoux; Wim G. J. Hol

Reports

Origin of Mountains on lo by Thrust Faulting and Large-Scale Mass Movements, pp. 1514-1517
Paul M. Schenk; Mark H. Bulmer

Single-Grain ⁴⁰ Ar- ³⁹ Ar Ages of Glauconies: Implications for the Geologic Time Scale and Global Sea Level Variations, pp. 1517-1519
Patrick E. Smith; Norman M. Evensen; Derek York; Gilles S. Odin

Distribution of Thiobacillus ferrooxidans and Leptospirillum ferrooxidans: Implications for Generation of Acid Mine Drainage, pp. 1519-1522
Matthew O. Schrenk; Katrina J. Edwards; Robert M. Goodman; Robert J. Hamers; Jillian F. Banfield

Materials with Negative Compressibilities in One or More Dimensions, pp. 1522-1524
Ray H. Baughman; Sven Stafström; Changxing Cui; Socrates O. Dantas

Large-Scale Molecular Dynamics Simulations of Dislocation Intersection in Chopper, pp. 1525-1527
S. J. Zhou; D. L. Preston; P. S. Lomdahl; D. M. Beazley

Muscle Regeneration by Bone Marrow-Derived Myogenic Progenitors, pp. 1528-1530
Giuliana Ferrari; Gabriella Cusella-De Angelis; Marcello Coletta; Egle Paolucci; Anna Stornaiuolo; Giulio Cossu; Fulvio Mavillo

Capacity for Plasticity in the Adult Owl Auditory System Expanded by Juvenile Experience, pp. 1531-1533
Eric I. Knudsen

A Model for the Mechanism of Human Topoisomerase I, pp. 1534-1541
Lance Stewart; Matthew R. Redinbo; Xiayang Qui; Wim G. J. Hol; James J. Champoux

Natural Ligand of Mouse CD1d1: Cellular Glycosylphosphatidylinositol, pp. 1541-1544
Sebastian Joyce; Amina S. Woods; Jonathan W. Yewdell; Jack R. Bennink; A. Dharshan de Silva; Alina Boesteanu; Steven P. Balk; Robert J. Cotter; Randy R. Brutkiewicz

A Screen for Genes Induced in the Suprachiasmatic Nucleus by Light, pp. 1544-1547
Mary E. Morris; N. Viswanathan; Sandra Kuhlman; Fred C. Davis; Charles J. Weitz

Role of PML in Cell Growth and the Retinoic Acid Pathway, pp. 1547-1551
Zhu Gang Wang; Laurent Delva; Mirella Gaboli; Roberta Rivi; Marco Giorgio; Carlos Cordon-Cardo; Frank Grosveld; Pier Paolo Pandolfi

Sphingosine-1-Phosphate as a Ligand for the G Protein-Coupled Receptor EDG-, pp. 1552-1555
Menq-Jer Lee; James R. van Brocklyn; Shobha Thangada; Catherine H. Liu; Arthur R. Hand; Ramil Menzeleev; Sarah Spiegel; Timothy Hla

Back Matter (41 pp.)

Previous Issue: New Series, Vol. 279, No. 5355, Feb. 27, 1998
Next Issue: New Series, Vol. 279, No. 5357, Mar. 13, 1998

Previous Issue: New Series, Vol. 279, No. 5356, Mar. 6, 1998
Next Issue: New Series, Vol. 279, No. 5358, Mar. 20, 1998

Front Matter (30 pp.)
Editorial: The Wake-Up Call We Dare Not Ignore, p. 1611
Gerald Wheeler

Letters

Unexpected Opportunity?, p. 1611
Daniel Joseph

After the Genome Database, pp. 1611+1613
Howard M. Cann

NMR Availability, p. 1613
Oleg Jardetzky

Eating Cake?, pp. 1613-1614
Jason M. Johnson

ICRISAT's Accomplishments, p. 1614
C. S. Prakash

Fractality in Nature, pp. 1614-1616
A. A. Tsonis; Ofer Biham; Ofer Malcai; Daniel A. Lidax; David Avnir

Responsive Chord, p. 1616
Stacy L. Daniels

Does Public Funding Corrupt?, pp. 1616-1617
Raymond R. White; Jason Hodin

Hopping Away?, p. 1617
L. Tarrant

Early Education of the Deaf, p. 1617
Henry J. Adler; Jeffrey Liebman; Robert M. Raphael; J. Tilak Ratnanather; Peter S. Steyger

Corrections and Clarifications: That Flashing Sound, p. 1617
Corrections and Clarifications: Many Faces of the Synapse, p. 1617
ScienceScope, p. 1621
Constance Holden

News and Comment

Keeping Up with Rita Colwell, pp. 1622-1623
Jeffrey Mervis

Physics Centers Forced to Go Private, pp. 1623-1624
Andrey Allakhverdov; Vladimir Pokrovsky

Lawsuit Targets Yellowstone Bug Deal, p. 1624
Elizabeth Pennisi

Clintons Push for R&D Boost, p. 1625
Andrew Lawler

Tuition Fees Fight Stalls Reform Law, p. 1625
Sabine Steghaus-Kovac

Scientists Flock to Explore China's `Site of the Century', pp. 1626-1627
Justin Wang

A Most Precocious Galaxy, p. 1627
Ann Finkbeiner

Cheapest Mission Finds Moon's Frozen Water, pp. 1628-1629
Richard A. Kerr

Celebrated Virus Hunters Set Up Shop in France, pp. 1629-1630
Michael Balter

Research News

New Role for Estrogen in Cancer?, pp. 1631-1633
Robert F. Service

Did the First Complex Cell Eat Hydrogen?, pp. 1633-1634
Gretchen Vogel

Surveyor Shows the Flat Face of Mars, p. 1634
Richard A. Kerr

Ancient Island Tools Suggest Homo erectus was a Seafarer, pp. 1635-1637
Ann Gibbons

Polyhedra Can Bend but Not Breathe, p. 1637
Dana Mackenzie

Random Samples, p. 1639
Constance Holden

Essays on Science and Society

What We Don't Know Does Hurt Us. How Scientific Illiteracy Hobbles Society, pp. 1640-1641
Norman Augustine

Science's Compass

Books

Quantum Devices, pp. 1649-1650
Transport in Nanostructures.
David K. Ferry; Stephen M. Goodnick

Review author[s]: Leo Kouwenhoven

Research

Between Foraging and Farming, pp. 1651-1652
Bruce D. Smith

Sound and Fracture, pp. 1652-1653
Fernando Lund

Mapping the Sensory Mosaic, pp. 1653-1654
Sharon L. Juliano

A Bridge to Control, pp. 1655-1656
Bruce Demple

On the Trans-Siberian Railroad, p. 1656
Julia Uppenbrink

Research Articles

A Massive Terraced Village Complex in Chihuahua, Mexico, 3000 Years before Present, pp. 1661-1664
Robert J. Hard; John R. Roney

Evolution of a Transfer RNA Gene Through a Point Mutation in the Anticodon, pp. 1665-1670
Margaret E. Saks; Jeffrey R. Sampson; John Abelson

Reports

Mars Global Surveyor

Mars Global Surveyor Mission: Overview and Status, pp. 1671-1672
A. L. Albee; F. D. Palluconi; R. E. Arvidson

The Structure of the Upper Atmosphere of Mars: In Situ Accelerometer Measurements from Mars Global Surveyor, pp. 1672-1676
G. M. Keating; S. W. Bougher; R. W. Zurek; R. H. Tolson; G. J. Cancro; S. N. Noll; J. S. Parker; T. J. Schellenberg; R. W. Shane; B. L. Wilkerson; J. R. Murphy; J. L. Hollingsworth; R. M. Haberle; M. Joshi; J. C. Pearl; B. J. Conrath; M. D. Smith; R. T. Clancy; R. C. Blanchard; R. G. Wilmoth; D. F. Rault; T. Z. Martin; D. T. Lyons; P. B. Esposito; M. D. Johnston; C. W. Whetzel; C. G. Justus; J. M. Babicke

Magnetic Field and Plasma Observations at Mars: Initial Results of the Mars Global Surveyor Mission, pp. 1676-1680
M. H. Acuña; J. E. P. Connerney; P. Wasilewski; R. P. Lin; K. A. Anderson; C. W. Carlson; J. McFadden; D. W. Curtis; D. Mitchell; H. Reme; C. Mazelle; J. A. Sauvaud; C. d'Uston; A. Cros; J. L. Medale; S. J. Bauer; P. Cloutier; M. Mayhew; D. Winterhalter; N. F. Ness

Early Views of the Martian Surface from the Mars Orbiter Camera of Mars Global Surveyor, pp. 1681-1685
M. C. Malin; M. H. Carr; G. E. Danielson; M. E. Davies; W. K. Hartmann; A. P. Ingersoll; P. B. James; H. Masursky; A. S. McEwen; L. A. Soderblom; P. Thomas; J. Veverka; M. A. Caplinger; M. A. Ravine; T. A. Soulanille; J. L. Warren

Topography of the Northern Hemisphere of Mars from the Mars Orbiter Laser Altimeter, pp. 1686-1692
D. E. Smith; M. T. Zuber; H. V. Frey; J. B. Garvin; J. W. Head; D. O. Muhleman; G. H. Pettengill; R. J. Phillips; S. C. Solomon; H. J. Zwally; W. B. Banerdt; T. C. Duxbury

Results from the Mars Global Surveyor Thermal Emission Spectrometer, pp. 1692-1698
P. R. Christensen; D. L. Anderson; S. C. Chase; R. T. Clancy; R. N. Clark; B. J. Conrath; H. H. Kieffer; R. O. Kuzmin; M. C. Malin; J. C. Pearl; T. L. Roush; M. D. Smith

The Postspinel Phase Boundary in Mg₂SiO₄ Determined by in Situ X-ray Diffraction, pp. 1698-1700
Tetsuo Irifune; Norimama Nishiyama; Koji Kuroda; Toru Inoue; Maiko Isshiki; Wataru Utsumi; Ken-ichi Funakoshi; Satoru Urakawa; Takeyuki Uchida; Tomoo Katsura; Osamu Ohtaka

Ultra-Low Velocity Zones Near the Core-Mantle Boundary from Broadband PKP Precursors, pp. 1701-1703
Lianxing Wen; Donald V. Helmberger

The Life and Death of "Bare" Viscous Bubbles, pp. 1704-1707
G. Debrégeas; P.-G. de Gennes; F. Brochard-Wyart

Deuterium in Comet C/1995 O1 (Hale-Bopp): Detection of DCN, pp. 1707-1710
Roland Meier; Tobias C. Owen; David C. Jewitt; Henry E. Matthews; Matthew Senay; Nicolas Biver; Dominique Bockelée-Morvan; Jacques Crovisier; Daniel Gautier

High-Selectivity, High-Flux Silica Membranes for Gas Separation, pp. 1710-1711
Renate M. de Vos; Henk Verweij

Identification of a Blue Photoluminescent Composite Material from a Combinatorial Library, pp. 1712-1714
Jingsong Wang; Young Yoo; Chen Gao; Ichiro Takeuchi; Xiaodong Sun; Hauyee Chang; X.-D. Xiang; Peter G. Schultz

Cortical Map Reorganization Enabled by Nucleus Basalis Activity, pp. 1714-1718
Michael P. Kilgard; Michael M. Merzenich

Activation of the OxyR Transcription Factor by Reversible Disulfide Bond Formation, pp. 1718-1721
Ming Zheng; Fredrik Åslund; Gisela Storz

Structural Basis for a Ca ²⁺ -Sensing Function of the Metabotropic Glutamate Receptors, pp. 1722-1725
Yoshihiro Kubo; Tomoyuki Miyashita; Yoshimichi Murata

Hyperinnervation of Neuromuscular Junctions Caused by GDNF Overexpression in Muscle, pp. 1725-1729
Quyen T. Nguyen; Alexander Sh. Parsadanian; William D. Snider; Jeff W. Lichtman

Conservation of T Cell Receptor Conformation in Epidermal gd Cells with Disrupted Primary V _γ Gene Usage, pp. 1729-1733
Caroline A. Mallick-Wood; Julia M. Lewis; Lauren I. Richie; Michael J. Owen; Robert E. Tigelaar; Adrian C. Hayday

Roles for ORC in M Phase and S Phase, pp. 1733-1737
Andrew Dillin; Jasper Rine

Recognition of Stress-Induced MHC Molecules by Intestinal Epithelial γδ T Cells, pp. 1737-1740
Veronika Groh; Alexander Steinle; Stefan Bauer; Thomas Spies

Back Matter (76 pp.)

Previous Issue: New Series, Vol. 279, No. 5356, Mar. 6, 1998
Next Issue: New Series, Vol. 279, No. 5358, Mar. 20, 1998

Previous Issue: New Series, Vol. 279, No. 5357, Mar. 13, 1998
Next Issue: New Series, Vol. 279, No. 5359, Mar. 27, 1998

Front Matter (26 pp.)
Editorial: Reaction Dynamics, p. 1831
Julia Uppenbrink

Letters

Lyme Disease and the Passenger Pigeon?, pp. 1831+1833
David E. Blockstein

The Paleobotanical Record, p. 1833
Patrick F. Fields

Free Calcium Signals, p. 1833
Lionel F. Jaffe

CIMMYT Budget, p. 1833
Tiffin D. Harris

Bacteriophage Collagen, p. 1834
Margaret C. M. Smith; Neil Burns; Jon R. Sayers; Julian A. Sorrell; Sherwood R. Casjens; Roger W. Hendrix; Jurgen Engel

The Oldest Human, pp. 1834-1835
Jean-Marie Robine; Michel Allard

ScienceScope, p. 1839
Constance Holden

News and Comment

Ames Tackles the Riddle of Life, pp. 1840-1841
Andrew Lawler

Russia Removes Obstacles to Projects, p. 1842
Richard Stone

Cancer Warriors Claim a Victory, pp. 1842-1843
Eliot Marshall

Asteroid Scare Provokes Soul-Searching, pp. 1843-1844
Gretchen Vogel

Funding Outlook Improves, but Job Crisis Remains, pp. 1844-1845
Nigel Williams

Gore Pushes Whole Earth Channel, p. 1845
Andrew Lawler

Japan Readies Helical Device to Probe Steady-State Plasmas, p. 1846
Dennis Normile

Research News

Training Lasers to be Chemists, pp. 1847-1848
Robert F. Service

Gentle Force of Entropy Bridges Disciplines, p. 1849
David Kestenbaum

Toxicologists Shed New Light on Old Poisons, pp. 1850-1851
Jocelyn Kaiser

Missing Link Ties Birds, Dinosaurs, pp. 1851-1852
Ann Gibbons

The Bare Bones of Catalysis, p. 1852
Erik Stokstad

Animals Thrive in an Avalanche's Wake, p. 1853
Kevin Krajick

Exploring How to Get at-and Eradicate-Hidden HIV, pp. 1854-1855
Jon Cohen

Getting an Inside Look at Cells' Chemistry, p. 1855
Kevin Boyd

Random Samples, p. 1857
Constance Holden

Essays on Science and Society

Science-Far More than Required High School Coursework, pp. 1858-1860
Robert Jackel; Jennie Schweitzer; Melsa Clarke; Shaila Musharoff; Praveen Yalamanchili; Vinnie McKeever; Michael Chu; Brian Sze; Megan McIlroy; Jonathan Woo; Jenitta Kwong

Science's Compass

Books

Picture of an Ancient World, pp. 1868-1869
Richardson's Guide to the Fossil Fauna of Mazon Creek.
Charles W. Shabica; Andrew A. Hay

Review author[s]: Carlton E. Brett

How to Teach Science, p. 1869
Student-Active Science. Models of Innovation in College Science Teaching.
Ann P. McNeal; Charlene D'Avanzo

Review author[s]: Stephen Arch

Research

Progress in Progressive Hearing Loss, pp. 1870-1871
Karen P. Steel

Promoter Logic, pp. 1871-1872
Gregory A. Wray

Chiral Order from Achiral Molecules, pp. 1872-1873
Gerd Heppke; Dirk Moro

Determining the Age of What Is Not There, p. 1874
Ira D. Sasowsky

Reaction Dynamics

Laser Control of Chemical Reactions, pp. 1875-1879
Richard N. Zare

Quantum Theory of Chemical Reaction Dynamics, pp. 1879-1882
David C. Clary

Gas-Phase Ionic Reactions: Dynamics and Mechanism of Nucleophilic Displacements, pp. 1882-1886
Michael L. Chabinyc; Stephen L. Craig; Colleen K. Regan; John I. Brauman

Chemical Dynamics in Proteins: The Photoisomerization of Retinal in Bacteriorhodopsin, pp. 1886-1891
Feng Gai; K. C. Hasson; J. Cooper McDonald; Philip A. Anfinrud

Electron Transfer: Classical Approaches and New Frontiers, pp. 1891-1895
Helmut Tributsch; Ludwig Pohlmann

Research Article

Genomic Cis-Regulatory Logic: Experimental and Computational Analysis of a Sea Urchin Gene, pp. 1896-1902
Chiou-Hwa Yuh; Hamid Bolouri; Eric H. Davidson

Reports

Self-Assembled Aggregates of Rod-Coil Block Copolymers and Their Solubilization and Encapsulation of Fullerenes, pp. 1903-1907
Samson A. Jenekhe; X. Linda Chen

Inducing and Viewing the Rotational Motion of a Single Molecule, pp. 1907-1909
B. C. Stipe; M. A. Rezaei; W. Ho

Detection of H₃⁺ in the Diffuse Interstellar Medium Toward Cygnus OB2 No. 12, pp. 1910-1913
B. J. McCall; T. Geballe; K. H. Hinkle; T. Oka

Design of a Surface Alloy Catalyst for Steam Reforming, pp. 1913-1915
F. Besenbacher; I. Chorkendorff; B. S. Clausen; B. Hammer; A. M. Molenbroek; J. K. Nørskov; I. Stensgaard

The Theropod Ancestry of Birds: New Evidence from the Late Cretaceous of Madagascar, pp. 1915-1919
Catherine A. Forster; Scott D. Sampson; Luis M. Chiappe; David W. Krause

Age and Origin of Carlsbad Cavern and Related Caves from ⁴0Ar/³9Ar of Alunite, pp. 1919-1922
Victor J. Polyak; William C. McIntosh; Necip Güven; Paula Provencio

Partial Hormone Resistance in Mice with Disruption of the Steroid Receptor Coactivator-1 (SRC-1) Gene, pp. 1922-1925
Jianming Xu; Yuhong Qiu; Francesco J. DeMayo; Sophia Y. Tsai; Ming-Jer Tsai; Bert W. O'Malley

Docking Phospholipase A₂ on Membranes Using Electrostatic Potential- Modulated Spin Relaxation Magnetic Resonance, pp. 1925-1929
Ying Lin; Robert Nielsen; Diana Murray; Wayne L. Hubbell; Colin Mailer; Bruce H. Robinson; Michael H. Gelb

Immunological Origins of Binding and Catalysis in a Diels-Alderase Antibody, pp. 1929-1933
Floyd E. Romesberg; Ben Spiller; Peter G. Schultz; Raymond C. Stevens

An Antibody exo Diels-Alderase Inhibitor Complex at 1.95 Angstrom Resolution, pp. 1934-1940
Andreas Heine; Enrico A. Stura; Jari T. Yli-Kauhaluoma; Changshou Gao; Qiaolin Deng; Brett R. Beno; Kendall N. Houk; Kim D. Janda; Ian A. Wilson

RNA Folding at Millisecond Intervals by Synchrotron Hydroxyl Radical Footprinting, pp. 1940-1943
Bianca Scalvi; Michael Sullivan; Mark R. Chance; Michael Brenowitz; Sarah A. Woodson

Kinetic Intermediates Trapped by Native Interactions in RNA Folding, pp. 1943-1946
Daniel K. Treiber; Martha S. Rook; Patrick P. Zarrinkar; James R. Williamson

Energy Transduction on the Nanosecond Time Scale: Early Structural Events in a Xanthopsin Photocycle, pp. 1946-1950
Benjamin Perman; Vukica Šrajer; Zhong Ren; Tsu-yi Teng; Claude Pradervand; Thomas Ursby; Dominique Bourgeois; Friederich Schotte; Michael Wulff; Remco Kort; Klaas Hellingwerf; Keith Moffat

Mutation in Transcription Factor POU4F3 Associated with Inherited Progressive Hearing Loss in Humans, pp. 1950-1954
Oz Vahava; Robert Morell; Eric D. Lynch; Sigal Weiss; Marjory E. Kagan; Nadav Ahituv; Jan E. Morrow; Ming K. Lee; Anne B. Skvorak; Cynthia C. Morton; Anat Blumenfeld; Moshe Frydman; Thomas B. Friedman; Mary-Claire King; Karen B. Avraham

FADD: Essential for Embryo Development and Signaling from Some, but Not All, Inducers of Apoptosis, pp. 1954-1958
Wen-Chen Yeh; José Luis de la Pompa; Mila E. McCurrach; Hong-Bing Shu; Andrew J. Elia; Arda Shahinian; Michelle Ng; Andrew Wakeham; Wilson Khoo; Kyran Mitchell; Wafik S. El-Deiry; Scott W. Lowe; David V. Goeddel

Redesigning Enzyme Topology by Directed Evolution, pp. 1958-1961
Gavin MacBeath; Peter Kast; Donald Hilvert

Dependence of BSAP Repressor and Activator Functions on BSAP Concentration, pp. 1961-1964
Jeffrey J. Wallin; Edwin R. Gackstetter; Marian Elliott Koshland

Tech.Sight

A New Window on Brain Research, pp. 1965-1966
Robert C. McKinstry; David A. Feinberg

Cpu by DNA?, p. 1967
Robert Sikorski; Richard Peters

Pinpoint Assays, pp. 1967-1968
Robert Sikorski; Richard Peters

Vitrual Meetings, p. 1968
Richard Peters; Robert Sikorski

Yeast Sites on the Net, p. 1968
Robert Sikorski; Richard Peters

Fluorescent Imaging System, p. 1969

Back Matter (35 pp.)

Previous Issue: New Series, Vol. 279, No. 5357, Mar. 13, 1998
Next Issue: New Series, Vol. 279, No. 5359, Mar. 27, 1998

Previous Issue: New Series, Vol. 279, No. 5358, Mar. 20, 1998
Next Issue: New Series, Vol. 280, No. 5360, Apr. 3, 1998

Front Matter (32 pp.)
Editorial: A Third Technological Revolution, p. 2019
Philip H. Abelson

Letters

Calculus Reform, pp. 2019+2021
Susan L. Ganter; D. J. Lewis; Deborah Hughes-Hallett

Math and Science Literacy, p. 2021
L. Caldbeck; Gretchen Vogel

Fishery and Reef Management, pp. 2021-2023
David R. Bellwood; Jeffrey M. Leis; Ilona C. Stobutzki; Peter F. Sale; Robert K. Cowen; Callum M. Roberts

Rapid-Wasting Disease: Pathogen or Predator?, pp. 2023-2025
Andrew Bruckner; Robin Bruckner

ScienceScope, p. 2029
Constance Holden

News and Comment

Beyond 'Big Iron' in Supercomputing, pp. 2030-2032
James Glanz

Motorola to Limit Signals Over Arecibo, p. 2032
Dana Mackenzie

Czech Research Review to Leave No Lab Unturned, p. 2033
Richard Stone

Physicist Gets Science, Education Posts, p. 2034
Pallava Bagla

Chemist to Lead New Science Ministry, p. 2034
Xiong Lei

Senate Panel Backs Large NIH Increase, p. 2035
Andrew Lawler

Darwin's House: A Monument to a Theory, pp. 2035-2036
Nigel Williams

Report Deplores Science-Media Gap, p. 2036
Jeffrey Mervis

First Alzheimer's Diagnosis Confirmed, p. 2037
Martin Enserink

Star Birth, Star Death, p. 2037

Research News

North America's Wars, pp. 2038-2040
Heather Pringle

A Hint of Unrest at Yucca Mountain, pp. 2040-2041
Richard A. Kerr

No-New-Neurons Dogma Loses Ground, pp. 2041-2042
Marcia Barinaga

Receptor Links Blood Vessels, Axons, p. 2042
Wade Roush

For Island Lizards, History Repeats Itself, p. 2043
Gretchen Vogel

Double Helix Doubles as Engineer, pp. 2043-2044
Sunny Bains

Weighing DNA for Fast Genetic Diagnosis, pp. 2044-2045
Joseph Alper

Making a Bigger Chill with Magnets, p. 2045
James Glanz

Random Samples, p. 2047
Constance Holden

Essays on Science and Society

Integrated Science and the Coming Century of the Environment, pp. 2048-2049
Edward O. Wilson

Science's Compass

Policy

Conservation Targets: Do They Help?, pp. 2060-2061
Michael E. Soulé; M. A. Sanjayan

Books

No Longer Alone, p. 2062
Bacteria as Multicellular Organisms.
James A. Shapiro; Martin Dworkin

Review author[s]: Roberto Kolter

Research

Shaking Without Quaking, pp. 2063-2064
Hiroo Kanamori

Origins of Hydrothermal Ores, pp. 2064-2065
H. L. Barnes; A. W. Rose

The Ultimate Spectroscopic Matrix?, pp. 2065-2066
K. K. Lehmann; G. Scoles

Expansion of the Allelic Exclusion Principle?, pp. 2067-2068
Andrew Chess

Planning for Biodiversity, pp. 2068-2069
Stuart L. Pimm; John H. Lawton

Review

The Quantum-Classical Metal, pp. 2071-2076
David G. Clarke; S. P. Strong; P. M. Chaikin; E. I. Chashechkina

Reports

Optical Amplification of Ligand-Receptor Binding Using Liquid Crystals, pp. 2077-2080
Vinay K. Gupta; Justin J. Skaife; Timothy B. Dubrovsky; Nicholas L. Abbott

Isolation of a Benzene Valence Isomer with One-Electron Phosphorus- Phosphorus Bonds, pp. 2080-2082
Yves Canac; Didier Bourissou; Antoine Baceiredo; Heinz Gornitzka; Wolfgang W. Schoeller; Guy Bertrand

Superfluidity Within a Small Helium-4 Cluster: The Microscopic Andronikashvili Experiment, pp. 2083-2086
Slava Grebenev; J. Peter Toennies; Andrei F. Vilesov

Elevation Change of the Southern Greenland Ice Sheet, pp. 2086-2088
Curt H. Davis; Craig A. Kluever; Bruce J. Haines

Earth's Background Free Oscillations, pp. 2089-2091
Naoki Suda; Kazunari Nawa; Yoshio Fukao

Formation of a Magmatic-Hydrothermal Ore Deposit: Insights with LA-ICP-MS Analysis of Fluid Inclusions, pp. 2091-2094
Andreas Audétat; Detlef Günther; Christoph A. Heinrich

Siliceous Tablets in the Larval Shells of Apatitic Discinid Brachiopods, pp. 2094-2096
Alwyn Williams; Maggie Cusack; James O. Buckman; Thomas Stachel

Anomalous Strain Accumulation in the Yucca Mountain Area, Nevada, pp. 2096-2100
Brian Wernicke; James L. Davis; Richard A. Bennett; Pedro Elósegui; Mark J. Abolins; Robert J. Brady; Martha A. House; Nathan A. Niemi; J. Kent Snow

Test of General Relativity and Measurement of the Lense-Thirring Effect with Two Earth Satellites, pp. 2100-2103
Ignazio Ciufolini; Erricos Pavlis; Federico Chieppa; Eduardo Fernandes-Vieira; Juan Pérez-Mercader

Quantitation of HIV-1-Specific Cytotoxic T Lymphocytes and Plasma Load of Viral RNA, pp. 2103-2106
Graham S. Ogg; Xia Jin; Sebastian Bonhoeffer; P. Rod Dunbar; Martin A. Nowak; Simon Monard; Jeremy P. Segal; Yunzhen Cao; Sarah L. Rowland-Jones; Vincenzo Cerundolo; Arlene Hurley; Martin Markowitz; David D. Ho; Douglas F. Nixon; Andrew J. McMichael

Biodiversity Assessment and Conservation Strategies, pp. 2106-2108
Albert S. van Jaarsveld; Stefanie Freitag; Steven L. Chown; Caron Muller; Stephanie Koch; Heath Hull; Chuck Bellamy; Martin Krüger; Sebastian Endrödy-Younga; Mervyn W. Mansell; Clarke H. Scholtz

Competition in Retinogeniculate Patterning Driven by Spontaneous Activity, pp. 2108-2112
Anna A. Penn; Patricio A. Riquelme; Marla B. Feller; Carla J. Shatz

Transcriptional and Posttranscriptional Plant Gene Silencing in Response to a Pathogen, pp. 2113-2115
Nadia S. Al-Kaff; Simon N. Covey; Maria M. Kreike; Anthony M. Page; Rachel Pinder; Philip J. Dale

Contingency and Determinism in Replicated Adaptive Radiations of Island Lizards, pp. 2115-2118
Jonathan B. Losos; Todd R. Jackman; Allan Larson; Kevin de Queiroz; Lourdes Rodríguez-Schettino

Monoallelic Expression of the Interleukin-2 Locus, pp. 2118-2121
Georg A. Holländer; Saulius Zuklys; Corinne Morel; Emiko Mizoguchi; Kathrine Mobisson; Stephen Simpson; Cox Terhorst; William Wishart; David E. Golan; Atul K. Bhan; Steven J. Burakoff

Structure of Nitric Oxide Synthase Oxygenase Dimer with Pterin and Substrate, pp. 2121-2126
Brian R. Crane; Andrew S. Arvai; Dipak K. Ghosh; Chaoqun Wu; Elizabeth D. Getzoff; Dennis J. Stuehr; John A. Tainer

Species Distributions, Land Values, and Efficient Conservation, pp. 2126-2128
Amy Ando; Jeffrey Camm; Stephen Polasky; Andrew Solow

AAAS News and Notes, p. 2131
S. L. Byrand

Back Matter (37 pp.)

Previous Issue: New Series, Vol. 279, No. 5358, Mar. 20, 1998
Next Issue: New Series, Vol. 280, No. 5360, Apr. 3, 1998

Previous Issue: New Series, Vol. 279, No. 5359, Mar. 27, 1998
Next Issue: New Series, Vol. 280, No. 5361, Apr. 10, 1998

Front Matter (29 pp.)
NetWatch, p. 7
Jocelyn Kaiser

Editorial: A Celebration of Life in the Trenches, p. 15
Thomas R. Cech

Letters

ASEAN Science, pp. 15+17
Jaap J. Beintema; Jeffrey W. Jacobs; Juang-Horng Chong Jr.

Transition at Russian Physics Centers, p. 18
Alain Gerard

Wizards of Microsoft, p. 18
Jeff Shrager; W. B. Wood

Kennewick Man, pp. 18-19
G. J. Sawyer

Reforming Calculus, p. 19
Ronald G. Douglas

Siberian Sediment Cores, p. 19
Hedi Oberhänsli

ScienceScope, p. 23
Constance Holden

News and Comment

Going Against the Flow in China, pp. 24-26
Xiong Lei

Industry Links Debated, Moon Shot Killed, pp. 26-27
Alexander Hellemans

New Hunt for the Roots of Resistance, p. 27
Dan Ferber

Future Brightens for Berkeley Facility, p. 28
Andrew Lawler

Sandia Steps Into the Fusion Race, p. 28
James Glanz

DOE Panel Slams Reactor Management, p. 29
Andrew Lawler

Asia Takes a Team Approach, pp. 29-30
Dennis Normile

France's Sequencers Aim to Join the Big League, pp. 30-31
Michael Balter

Research News

Death by Dozens of Cuts, pp. 32-34
Marcia Barinaga

Physicists Find the Last of the Mesons, p. 35
David Kestenbaum

Inbreeding's Kiss of Death, p. 35
Jocelyn Kaiser

Transferred Gene Helps Plants Weather Cold Snaps, p. 36
Elizabeth Pennisi

Magnetic Brain Imaging Traces A Stairway to Memory, p. 37
James Glanz

Planetary Scientists Sample Ice, Fire, and Dust in Houston, pp. 38-39
Richard A. Kerr

Random Samples, p. 41
Constance Holden

Essays on Science and Society

A Celebration of Difference: Science and Democracy in India, pp. 42-43
Shiv Visvanathan

Science's Compass

Books

Structuring Nurture, p. 54
Life's Other Secret. The New Mathematics of the Living World.
Ian Stewart

Review author[s]: Sunetra Gupta

Rock and the Role of Microbiology, pp. 54-55
Geomicrobiology: Interactions Between Microbes and Minerals.
Jillian F. Banfield; Kenneth H. Nealson

Review author[s]: Derek R. Lovley

Research

The Vision of the Pore, pp. 56-57
Clay Armstrong

How Old Is the Flower and the Fly?, pp. 57-59
Conrad C. Labandeira

Memory and Awareness, pp. 59-60
Daniel L. Schacter

Photochemistry of Ozone: Surprises and Recent Lessons, pp. 60-61
A. R. Ravishankara; G. Hancock; M. Kawasaki; Y. Matsumi

Review

The Formation of Chondrules: Petrologic Tests of the Shock Wave Model, pp. 62-67
Harold C. Connolly Jr.; Stanley G. Love

Research Articles

The Structure of the Potassium Channel: Molecular Basis of K⁺ Conduction and Selectivity, pp. 69-77
Declan A. Doyle; João Morais Cabral; Richard A. Pfuetzner; Anling Kuo; Jacqueline M. Gulbis; Steven L. Cohen; Brian T. Chait; Roderick MacKinnon

Classical Conditioning and Brain Systems: The Role of Awareness, pp. 77-81
Robert E. Clark; Larry R. Squire

Reports

Ultrasound-Stimulated Vibro-Acoustic Spectrography, pp. 82-85
Mostafa Fatemi; James F. Greenleaf

Flower-Associated Brachycera Flies as Fossil Evidence for Jurassic Angiosperm Origins, pp. 85-88
Dong Ren

Capture of Interplanetary and Interstellar Dust by the Jovian Magnetosphere, pp. 88-91
Joshua E. Colwell; Mihály Horanyi; Eberhard Grün

Time Scales and Heterogeneous Structure in Geodynamic Earth Models, pp. 91-95
Hans-Peter Bunge; Mark A. Richards; Carolina Lithgow-Bertelloni; John R. Baumgardner; Stephen P. Grand; Barbara A. Romanowicz

Strong Regularities in World Wide Web Surfing, pp. 95-97
Bernardo A. Huberman; Peter L. T. Pirolli; James E. Pitkow; Rajan M. Lukose

Searching the World Wide Web, pp. 98-100
Steve Lawrence; C. Lee Giles

Interaction of Short-Range Repressors with Drosophila CtBP in the Embryo, pp. 101-104
Yutaka Nibu; Hailan Zhang; Michael Levine

Arabidopsis CBF1 Overexpression Induces COR Genes and Enhances Freezing Tolerance, pp. 104-106
Kirsten R. Jaglo-Ottosen; Sarah J. Gilmour; Daniel G. Zarka; Oliver Schabenberger; Michael F. Thomashow

Structural Conservation in Prokaryotic and Eukaryotic Potassium Channels, pp. 106-109
Roderick MacKinnon; Steven L. Cohen; Anling Kuo; Alice Lee; Brian T. Chait

Requirement of Ras-GTP-Raf Complexes for Activation of Raf-1 by Protein Kinase C, pp. 109-112
Richard Marais; Yvonne Light; Clive Mason; Hugh Paterson; Michael F. Olson; Christopher J. Marshall

Integration of Environmental, Agronomic, and Economic Aspects of Fertilizer Management, pp. 112-115
Pamela A. Matson; Rosamond Naylor; Ivan Ortiz-Monasterio

Induction of Lens Differentiation by Activation of a bZIP Transcription Factor, L-Maf, pp. 115-118
Hajime Ogino; Kunio Yasuda

Back Matter (46 pp.)

Previous Issue: New Series, Vol. 279, No. 5359, Mar. 27, 1998
Next Issue: New Series, Vol. 280, No. 5361, Apr. 10, 1998

Previous Issue: New Series, Vol. 280, No. 5360, Apr. 3, 1998
Next Issue: New Series, Vol. 280, No. 5362, Apr. 17, 1998

Front Matter (43 pp.)
Net Watch, p. 171
Jocelyn Kaiser

Editorial: Halting the March of the Immune Defenses, p. 179
Arthur Weiss; Linda J. Miller

Letters

Mideast Peace and Scientific Collaboration, p. 179
Scot Silverstein

Southeast Asian Scientists and U.S. Graduate Programs, pp. 179+181-183
Peter A. Cohen

Anatomy of "Regenerating Axons", pp. 183-184
Roberto Pallini; Ying Li; Pauline M. Field; Geoffrey Raisman

Traffic Jams on the Internet, pp. 184-185
Jon Crowcroft; Michael Luby; Vern Paxson; Bernardo Huberman; Rajan M. Lukose

Genus Correction, p. 185
Catherine A. Forster; Scott D. Sampson; Luis M. Chiappe; David W. Krause

Corrections and Clarifications: Partnering of the Red Sea Lets Scientists Bond, p. 185
Corrections and Clarifications: Fractality in Nature, p. 185
Corrections and Clarifications: Clinton Names Adviser, NSF Chief, p. 185
ScienceScope, p. 189
Richard Stone

News and Comment

Kennewick Man's Trials Continue, pp. 190-192
Virginia Morell

Pharma Giant Creates Genomics Institute, p. 193
Elizabeth Pennisi

Panel Scores EPA on Clean Air Science, pp. 193-194
Jocelyn Kaiser

Academy Rallies Teachers on Evolution, p. 194
Constance Holden

Advocacy Mailing Draws Fire, p. 195
David Malakoff

Peña Quits; Moler Seen Moving Up, p. 195
Andrew Lawler

Senate Resolution Spotlights R&D, p. 196
Andrew Lawler

'A Big Deal,' But a Complex Hand to Play, p. 196
Eliot Marshall

R&D Agencies Spell out Goals Under New Accountability Law, p. 197
Jeffrey Mervis

Research News

T Cells on the Mucosal Frontline, pp. 198-200
Nigel Williams

The Subtle Flirtation of Ultracold Atoms, pp. 200-201
James Glanz

Flying by the Seat of Their Halteres, pp. 201-202
Elizabeth Pennisi

Ozone Loss, Greenhouse Gases Linked, p. 202
Richard A. Kerr

Jumbo Gene Offers Clue to Parkinson's, p. 203
Mutsumi Stone

El Niño Brings Winter of Discontent, p. 203
Melissa Blouin

Viruses Have Many Ways to be Unwelcome Guests, pp. 204-205
Michael Balter

Einstein's Theory Rings True, p. 205
Andrew Watson

Random Samples, p. 207
Constance Holden

Essays on Science and Society

From the World of Science to the World of Research?, pp. 208-209
Bruno Latour

Science's Compass

Books

Dinosaurs for Adults, p. 223
The Complete Dinosaur.
James O. Farlow; Michael K. Brett-Surman

Review author[s]: Lawrence M. Witmer

Almost All Things Dinosaurian, p. 224
Encyclopedia of Dinosaurs.
Philip J. Currie; Kevin Padian

Review author[s]: John Ruben

Research

The Evidence of Small Things, p. 225
Daniel Gammon

One for All and All for One, pp. 226-227
Roberto Kolter; Richard Losick

The Numbers Game for Virus-Specific CD8⁺ T Cells, p. 227
Peter C. Doherty

The Advantages of Superposition, p. 228
Lov K. Grover

Fast Searches with Nuclear Magnetic Resonance Computers, p. 229
Jonathan A. Jones

Turning the Immune System Off

Natural and Engineered Disorders of Lymphocyte Development, pp. 237-243
Alain Fischer; Bernard Malissen

Homeostasis and Self-Tolerance in the Immune System: Turning Lymphocytes Off, pp. 243-248
Luk Van Parijs; Abul K. Abbas

Viral Strategies of Immune Evasion, pp. 248-253
Hidde L. Ploegh

Reports

Temperature-Induced Momentum-Dependent Spectral Weight Transfer in Bi₂Sr₂CaCu₂O _8+δ, pp. 259-262
Z.-X. Shen; P. J. White; D. L. Feng; C. Kim; G. D. Gu; H. Ikeda; R. Yoshizaki; N. Koshizuka

Optical Studies of Individual InAs Quantum Dots in GaAs: Few-Particle Effects, pp. 262-264
L. Landin; M. S. Miller; M.-E. Pistol; C. E. Pryor; L. Samuelson

Delayed Fracture of an Inhomogeneous Soft Solid, pp. 265-267
Daniel Bonn; Hamid Kellay; Michaël Prochnow; Karim Ben-Djemiaa; Jacques Meunier

Thermographic Selection of Effective Catalysts from an Encoded Polymer- Bound Library, pp. 267-270
Steven J. Taylor; James P. Morken

Polyolefin Spheres from Metallocenes Supported on Noninteracting Polystyrene, pp. 270-273
Stephen B. Roscoe; Jean M. J. Fréchet; John F. Walzer; Anthony J. Dias

Friction Anisotropy and Asymmetry of a Compliant Monolayer Induced by a Small Molecular Tilt, pp. 273-275
M. Liley; D. Gourdon; D. Stamou; U. Meseth; T. M. Fischer; C. Lautz; H. Stahlberg; H. Vogel; N. A. Burnham; C. Duschl

Generation of Intestinal T Cells from Progenitors Residing in Gut Cryptopatches, pp. 275-278
Hisashi Saito; Yutaka Kanamori; Toshitada Takemori; Hideo Nariuchi; Eiro Kubota; Hiromi Takahashi-Iwanaga; Toshihiko Iwanaga; Hiromichi Ishikawa

Crystal Structure and Evolution of a Transfer RNA Splicing Enzyme, pp. 279-284
Hong Li; Christopher R. Trotta; John Abelson

Conservation of Substrate Recognition Mechanisms by tRNA Splicing Endonucleases, pp. 284-286
Stefania Fabbri; Paolo Fruscoloni; Emanuela Bufardeci; Elisa Di Nicola Negri; Maria I. Baldi; Domenica Gandini Attardi; Emilio Mattoccia; Glauco P. Tocchini-Valentini

Ribosome-Catalyzed Peptide-Bond Formation with an A-Site Substrate Covalently Linked to 23S Ribosomal RNA, pp. 286-289
Rachel Green; Christopher Switzer; Harry F. Noller

Visual Input to the Efferent Control System of a Fly's "Gyroscope", pp. 289-292
Wai Pang Chan; Frederick Prete; Michael H. Dickinson

A Marine Natural Product Inhibitor of Kinesin Motors, pp. 292-295
Roman Sakowicz; Michael S. Berdelis; Krishanu Ray; Christine L. Blackburn; Cordula Hopmann; D. John Faulkner; Lawrence S. B. Goldstein

The Involvement of Cell-to-Cell Signals in the Development of a Bacterial Biofilm, pp. 295-298
David G. Davies; Matthew R. Parsek; James P. Pearson; Barbara H. Iglewski; J. W. Costerton; E. P. Greenberg

Coupling Termination of Transcription to Messenger RNA Maturation in Yeast, pp. 298-301
Charles E. Birse; Lionel Minvielle-Sebastia; Barbara A. Lee; Walter Keller; Nick J. Proudfoot

Rejoining of DNA by the RAG1 and RAG2 Proteins, pp. 301-303
Meni Melek; Martin Gellert; Dik C. van Gent

Back Matter (41 pp.)

Previous Issue: New Series, Vol. 280, No. 5360, Apr. 3, 1998
Next Issue: New Series, Vol. 280, No. 5362, Apr. 17, 1998

Previous Issue: New Series, Vol. 280, No. 5361, Apr. 10, 1998
Next Issue: New Series, Vol. 280, No. 5363, Apr. 24, 1998

Front Matter (20 pp.)
Netwatch, p. 351
Jocelyn Kaiser

Editorial: On the Future of Scholarly Journals, p. 359
Alan M. Edelson

Letters

Great Expectations in China, p. 359
Zhong-Ren Chen

Owls and Early Learning, pp. 359+361
David Elkind; Martin J. Steinbach

Natron Trade, 2000 B.C., p. 361
Thomas Pauls

Kaposi's Sarcoma and Protection from HIV Dementia, pp. 361-362
Knut Liestoel; Anne K. Goplen; Oona Dunlop; Johan N. Bruun; Jan Moehlen; T. Baldeweg; J. Catalan; B. G. Gazzard; R. A. Weiss; C. Boshoff

Oliver Update, pp. 362-363
John J. Ely; Charleen M. Moore

Corrections and Clarifications: A Bridge to Control, p. 363
Corrections and Clarifications: Topography of the Northern Hemisphere of Mars from the Mars Orbiter Laser Altimiter, p. 363
Corrections and Clarifications: Requirement for GD3 Ganglioside in CD95- and Ceramide-Induced Apoptosis, p. 363
ScienceScope, p. 367
Constance Holden

News and Comment

DOE Moves to Higher Ground, pp. 368-370
Andrew Lawler

Kansas City Institute's Big Plans, pp. 370-371
Eliot Marshall

Restored Wetlands Flunk Real-World Test, pp. 371-372
David Malakoff

Bailout for Drug Research Institute, p. 372
Richard Stone

Science Overrides Politics for East Asian Monsoon Study, p. 373
Dennis Normile; Li Hui

Science Moves Up Ladder in Push for Sustainable Growth, pp. 374-375
Pallava Bagla

Mixed Results from the Labrador Sea, p. 375
Steve Nadis

Research News

Listening in on the Brain, pp. 376-378
Marcia Barinaga

A Water Generator in the Orion Nebula, p. 378
James Glanz

A Possible New Approach to Combating Staph Infections, p. 379
Evelyn Strauss

Anthropologists Probe Genes, Brains at Annual Meeting, pp. 380-381
Ann Gibbons

Fiery Io Models Earth's First Days, pp. 381-382
Richard A. Kerr

A Record in Converting Photons to Fuel, p. 382
Robert F. Service

Signaling Path may Lead to Better Heart-Failure Therapies, p. 383
Marcia Barinaga

Random Samples, p. 385
Constance Holden

Essays on Science and Society

Movement of the People, pp. 386-387
Roald Hoffmann

Science's Compass

Policy

Bridging the Racial Divide on the Internet, pp. 390-391
Donna L. Hoffman; Thomas P. Novak

Books

Images of an Inventor Hero, pp. 392-393
Alexander Graham Bell. The Life and Times of the Man Who Invented the Telephone.
Edwin S. Grosvenor; Morgan Wesson

Review author[s]: Robert Friedel

How the Land Turned Green, p. 393
The Origin and Early Diversification of Land Plants. A Cladistic Study.
Paul Kenrick; Peter R. Crane

Review author[s]: Richard Olmstead

Research

Proteases, Processing, and Thymic Selection, pp. 394-395
Peter Cresswell

The Future of Human Longevity: A Demographer's Perspective, pp. 395-397
John R. Wilmoth

One or Three Cambrian Radiations?, pp. 397-398
Guillaume Balavoine; André Adoutte

Rethinking Solution NMR, pp. 398-399
Warren S. Warren

Review

Stormy Weather in Galaxy Clusters, pp. 400-404
Jack O. Burns

Reports

Protactinium-231 and Thorium-230 Abundances and High Scavenging Rates in the Western Arctic Ocean, pp. 405-407
Henrietta N. Edmonds; S. Bradley Moran; John A. Hoff; John N. Smith; R. Lawrence Edwards

Is GRO J1744-28 a Strange Star?, pp. 407-409
K. S. Cheng; Z. G. Dai; D. M. Wei; T. Lu

Two-Fraction Model of Initial Sediment Motion in Gravel-Bed Rivers, pp. 410-412
Peter R. Wilcock

Formation of Carbonates in the Tatahouine Meteorite, pp. 412-414
J. A. Barrat; Ph. Gillet; C. Lécuyer; S. M. F. Sheppard; M. Lesourd

Oxygen Isotopic Abundances in Calcium-Aluminum-Rich Inclusions from Ordinary Chondrites: Implications for Nebular Heterogeneity, pp. 414-418
Kevin D. McKeegan; Laurie A. Leshin; Sara S. Russell; Glenn J. MacPherson

Osmium Isotopic Evidence for Ancient Subcontinental Lithospheric Mantle Beneath the Kerguelen Islands, Southern Indian Ocean, pp. 418-421
Deborah R. Hassler; Nobumichi Shimizu

Unitary Control in Quantum Ensembles: Maximizing Signal Intensity in Coherent Spectroscopy, pp. 421-424
S. J. Glaser; T. Schulte-Herbrüggen; M. Sieveking; O. Schedletzky; N. C. Nielsen; O. W. Sørensen; C. Griesinger

A Monolithic Photovoltaic-Photoelectrochemical Device for Hydrogen Production via Water Splitting, pp. 425-427
Oscar Khaselev; John A. Turner

Gastrointestinal Tract as a Major Site of CD4⁺T Cell Depletion and Viral Replication in SIV Infection, pp. 427-431
Ronald S. Veazey; MaryAnn DeMaria; Laura V. Chalifoux; Daniel E. Shvetz; Douglas R. Pauley; Heather L. Knight; Michael Rosenzweig; R. Paul Johnson; Ronald C. Desrosiers; Andrew A. Lackner

Association of the AP-3 Adaptor Complex with Clathrin, pp. 431-434
Esteban C. Dell'Angelica; Judith Klumperman; Willem Stoorvogel; Juan S. Bonifacino

NMR Structure of a Classical Pseudoknot: Interplay of Single- and Double- Stranded RNA, pp. 434-438
Michaël H. Kolk; Marinette van der Graaf; Sybren S. Wijmenga; Cornelis W. A. Pleij; Hans A. Heus; Cornelis W. Hilbers

Autoinducer of Virulence as a Target for Vaccine and Therapy Against Staphylococcus aureus, pp. 438-440
Naomi Balaban; Tzipora Goldkorn; Rachael T. Nhan; Luong B. Dang; Steven Scott; Rose M. Ridgley; Avraham Rasooly; Susan C. Wright; James W. Larrick; Reuven Rasooly; James R. Carlson

Impacts of Rising Atmospheric Carbon Dioxide on Model Terrestrial Ecosystems, pp. 441-443
T. H. Jones; L. J. Thompson; J. H. Lawton; T. M. Bezemer; R. D. Bardgett; T. M. Blackburn; K. D. Bruce; P. F. Cannon; G. S. Hall; S. E. Hartley; G. Howson; C. G. Jones; C. Kampichler; E. Kandeler; D. A. Ritchie

Control of Alternative Splicing of Potassium Channels by Stress Hormones, pp. 443-446
Jiuyong Xie; David P. McCobb

Maternal Control of Embryogenesis by MEDEA, a Polycomb Group Gene in Arabidopsis, pp. 446-450
Ueli Grossniklaus; Jean-Philippe Vielle-Calzada; Marilu A. Hoeppner; Wendy B. Gagliano

Cathepsin L: Critical Role in li Degradation and CD4 T Cell Selection in the Thymus, pp. 450-453
Terry Nakagawa; Wera Roth; Phillip Wong; Andrew Nelson; Andrew Farr; Jan Deussing; Jose A. Villadangos; Hidde Ploegh; Christoph Peters; Alexander Y. Rudensky

Tech.Sight

Autonomous Navigation and the Sojourner Microrover, pp. 454-455
J. Matijevic

Synthetic Protease Switch, p. 456
Robert Sikorski; Richard Peters

Beauty in Simplicity, pp. 456-457
Richard Peters; Robert Sikorski

Showing Off Your Lab, p. 457
Richard Peters; Robert Sikorski

Monoclonal Antibodies, p. 458

Back Matter (26 pp.)

Previous Issue: New Series, Vol. 280, No. 5361, Apr. 10, 1998
Next Issue: New Series, Vol. 280, No. 5363, Apr. 24, 1998

Previous Issue: New Series, Vol. 280, No. 5362, Apr. 17, 1998
Next Issue: New Series, Vol. 280, No. 5364, May 1, 1998

Front Matter (32 pp.)
NetWatch, p. 491
Jocelyn Kaiser

Editorial: Science Policy in Canada, p. 499
Jon Gerrard

Letters

Coral Disease, pp. 499+501
James M. Cervino; T. J. Goreau; R. L. Hayes; L. Kaufman; I. Nagelkerken; K. Patterson; J. W. Porter; G. W. Smith; C. Quirolo

Origin of the Eukaryotic Nucleus, pp. 501+503
Kathleen Sandman; John N. Reeve

Tracing Steps of the Earliest Americans, p. 503
Colin O. Hermans

The Brain's Normal Function, p. 503
Alessandro Laviano; Filippo Rossi Fanelli; Michael M. Meguid

The Black Sea: A Freshwater Lake?, pp. 503-504
Martin Burkhard; William B. F. Ryan; Walter C. Pitman III

Fertilizer Use, p. 504
Charles R. Frink

Hidden Lives of Seals, p. 505
G. Carleton Ray; W. A. Watkins; D. Wartzok

Neither Inbred Nor Extinct, p. 505
Clifford J. Jolly

ScienceScope, p. 509
Constance Holden

News and Comment

Survival Test for Kenya's Wildlife, pp. 510-512
Michael McRae

U.S. Blacklists Russian Institutes, p. 513
Richard Stone

New Life for Research Centers, p. 513
Elizabeth Finkel

Gamma Blast from Way, Way Back, p. 514
James Glanz

UC Fights Tobacco Company Subpoena, pp. 514-515
Eliot Marshall

Research Drought Looms after Neurolab Mission, pp. 515-516
Andrew Lawler

A Blow to the 'Grandmother Theory', p. 516
Ann Gibbons

Research News

Tracking Insulin to the Mind, pp. 517-519
Ingrid Wickelgren

From a Turbulent Maelstrom, Order, p. 519
James Glanz

Genes may Link Ancient Eurasians, Native Americans, p. 520
Virginia Morell

Versatile Gene Uptake System Found in Cholera Bacterium, pp. 521-522
Elizabeth Pennisi

Models Win Big in Forecasting El Niño, pp. 522-523
Richard A. Kerr

Spying on Solar Systems in the Making, pp. 523-524
Govert Schilling

Catalytic Explanation for Natural Gas, pp. 524-525
Robert F. Service

Will New Catalyst Finally Tame Methane?, p. 525
Robert F. Service

Random Samples, p. 527
Constance Holden

Essays on Science and Society

Science and Scientists in China, pp. 528-529
Chen-Lu Tsou

Science's Compass

Policy

The Interdependence of Science and Law, pp. 537-538
Stephen Breyer

Books

Power and the People, pp. 539-540
Consuming Power. A Social History of American Energies.
David E. Nye

Review author[s]: M. Granger Morgan

The Civic Importance of Chemistry, p. 540
Justus von Liebig. The Chemical Gatekeeper.
William H. Brock

Review author[s]: Mark R. Finlay

Research

Sieves in Sequence, p. 541
Alan R. Fersht

Archaeal Means and Extremes, pp. 542-543
Edward DeLong

It was the Best of Times, It was the Worst of Times, pp. 544-545
Phil Jones

Nanowires: Small is Beautiful, pp. 545-546
Gerhard Fasol

Review

Structure and Function in the Nucleus, pp. 547-553
Angus I. Lamond; William C. Earnshaw

Reports

Intense Sub-Kilometer-Scale Boundary Layer Rolls Observed in Hurricane Fran, pp. 555-557
Joshua Wurman; Jennifer Winslow

Switching Supramolecular Polymeric Materials with Multiple Length Scales, pp. 557-560
J. Ruokolainen; R. Mäkinen; M. Torkkeli; T. Mäkelä; R. Serimaa; G. ten Brinke; O. Ikkala

Platinum Catalysts for the High-Yield Oxidation of Methane to a Methanol Derivative, pp. 560-564
Roy A. Periana; Douglas J. Taube; Scott Gamble; Henry Taube; Takashi Satoh; Hiroshi Fujii

The Lost Colony and Jamestown Droughts, pp. 564-567
David W. Stahle; Malcolm K. Cleaveland; Dennis B. Blanton; Matthew D. Therrell; David A. Gay

Tunneling into a Single Magnetic Atom: Spectroscopic Evidence of the Kondo Resonance, pp. 567-569
V. Madhavan; W. Chen; T. Jamneala; M. F. Crommie; N. S. Wingreen

Clouds of High Contrast on Uranus, pp. 570-572
Erich Karkoschka

Brain Activity During Speaking: From Syntax to Phonology in 40 Milliseconds, pp. 572-574
Miranda van Turennout; Peter Hagoort; Colin M. Brown

Targeting the Receptor-G_q Interface to Inhibit in Vivo Pressure Overload Myocardial Hypertrophy, pp. 574-577
Shahab A. Akhter; Louis M. Luttrell; Howard A. Rockman; Guido Laccarino; Robert J. Lefkowitz; Walter J. Koch

Enzyme Structure with Two Catalytic Sites for Double-Sieve Selection of Substrate, pp. 578-582
Osamu Nureki; Dmitry G. Vassylyev; Masaru Tateno; Atsushi Shimada; Takashi Nakama; Shuya Fukai; Mitiko Konno; Tamara L. Hendrickson; Paul Schimmel; Shigeyuki Yokoyama

Dependence of Germinal Center B Cells on Expression of CD21/CD35 for Survival, pp. 582-585
Michael B. Fischer; Siegfried Goerg; LiMing Shen; Andrey P. Prodeus; Christopher C. Goodnow; Garnett Kelsoe; Michael C. Carroll

Visualization of Single RNA Transcripts in Situ, pp. 585-590
Andrea M. Femino; Fredric S. Fay; Kevin Fogarty; Robert H. Singer

In Situ Visualization of DNA Double-Strand Break Repair in Human Fibroblasts, pp. 590-592
Benjamin E. Nelms; Richard S. Maser; James F. MacKay; Max G. Lagally; John H. J. Petrini

Formation of a Preinitiation Complex by S-Phase Cyclin CDK-Dependent Loading of Cdc45p onto Chromatin, pp. 593-596
Lee Zou; Bruce Stillman

Functional Interaction of an Axin Homolog, Conductin, with β-Catenin, APC, and GSK3β, pp. 596-599
Jurgen Behrens; Boris-Alexander Jerchow; Martin Wurtele; Jan Grimm; Christian Asbrand; Ralph Wirtz; Michael Kuhl; Doris Wedlich; Walter Birchmeier

Activation of the Protein Kinase p38 in the Spindle Assembly Checkpoint and Mitotic Arrest, pp. 599-602
Katsuya Takenaka; Tetsuo Moriguchi; Eisuke Nishida

Supramolecular Structure of the Salmonella typhimurium Type III Protein Secretion System, pp. 602-605
Tomoko Kubori; Yukiyasu Matsushima; Dai Nakamura; Jaimol Uralil; Maria Lara-Tejero; Anand Sukhan; Jorge E. Gálan; Shin-Ichi Aizawa

A Distinctive Class of Integron in the Vibrio cholerae Genome, pp. 605-608
Didier Mazel; Broderick Dychinco; Vera A. Webb; Julian Davies

AAAS News and Notes, p. 614
S. L. Byrand

Back Matter (26 pp.)

Previous Issue: New Series, Vol. 280, No. 5362, Apr. 17, 1998
Next Issue: New Series, Vol. 280, No. 5364, May 1, 1998

Previous Issue: New Series, Vol. 280, No. 5363, Apr. 24, 1998
Next Issue: New Series, Vol. 280, No. 5365, May 8, 1998

Front Matter (26 pp.)
NetWatch, p. 647
Jocelyn Kaiser

Editorial: New Zealand's Foresight Project, p. 655
Maurice Williamson

Letters

The Gentle Force of Entropy, pp. 655+657
Arthur W. Adamson

Bioresources and "Biopiracy" in Brazil, p. 657
Marina Silva

Super-Accelerators and International Collaboration, p. 657
Björn H. Wiik

Shifty Eyes, p. 657
August L. Reader

Funding Themselves and Others, pp. 657-658
Herbert F. Voigt; Dana D. Ricciardi; Ernst-August Seyfarth

Gray Whales in Cold Water, pp. 658-659
Martha E. Heath; John E. Heyning; James G. Mead

Ring Laser Design, p. 659
M. Schneider; U. Schreiber; G. E. Stedman

Corrections and Clarifications: Visual Input to the Efferent Control System of a Fly's 'Gyroscope', p. 659
Corrections and Clarifications: Clues to Unsolved Arsenic Case, p. 659
ScienceScope, p. 663
Constance Holden

News and Comment

An Anxious Time for Swiss Science, pp. 664-665
Robert Koenig

Report Sees More Overruns, Delays, p. 666
Andrew Lawler

Counting NIH's Fiscal Chickens, pp. 666-667
Eliot Marshall

Private Help for a Public Database?, pp. 667-668
Eliot Marshall

Ulysses Laps Sun, Inspires New Missions, p. 668
Alexander Hellemans

New Projects Receive Boost as Cuts Pinch Current Work, p. 669
Dennis Normile

World's Biggest Telescope is About to See the Light, pp. 670-671
Govert Schilling

Research News

Genome Data Shake Tree of Life, pp. 672-674
Elizabeth Pennisi

X-ray Flickers Reveal a Space Warp, pp. 674-675
David Kestenbaum

Genes Put Mammals in Age of Dinosaurs, pp. 675-676
Ann Gibbons

New Clue to How Anthrax Kills, p. 676
Evelyn Strauss

Bison Prime Prairie Biodiversity, p. 677
Jocelyn Kaiser

'Monogamous' Gibbons Really Swing, pp. 677-678
Ann Gibbons

Last Hurrah for an Infrared Satellite, p. 678
Govert Schilling

Deep-Sea Coral Records Quick Response to Climate, p. 679
Richard A. Kerr

Random Samples, p. 681
Constance Holden

Essays on Science and Society

Extensions of "The Tragedy of the Commons", pp. 682-683
Garrett Hardin

Science's Compass

Policy

The Patenting of DNA, pp. 689-690
John J. Doll

Books

A Mole Brought to Light, pp. 691-692
Bombshell. The Secret Story of America's Unknown Atomic Spy Conspiracy.
Joseph Albright; Marcia Kunstel

Review author[s]: David Holloway

Tales of Terrible Toxins, p. 692
The Clostridia: Molecular Biology and Pathogenesis.
Julian I. Rood

Review author[s]: Michael Young

Research

Explosions and Dissociations, pp. 693-694
Henry Hutchinson

Microbial Control of Oceanic Carbon Flux: The Plot Thickens, pp. 694-696
Farooq Azam

Triplet-Repeat Transcripts: A Role for RNA in Disease, pp. 696-697
Robert H. Singer

Review

Can Patents Deter Innovation? The Anticommons in Biomedical Research, pp. 698-701
Michael A. Heller; Rebecca S. Eisenberg

Reports

Ordering of Ruthenium Cluster Carbonyls in Mesoporous Silica, pp. 705-708
Wuzong Zhou; John Meurig Thomas; Douglas S. Shephard; Brian F. G. Johnson; Don Ozkaya; Thomas Maschmeyer; Robert G. Bell; Qingfeng Ge

A Trivalent System from Vancomycin·D-Ala-D-Ala with Higher Affinity Than Avidin·Biotin, pp. 708-711
Jianghong Rao; Joydeep Lahiri; Lyle Isaacs; Robert M. Weis; George M. Whitesides

An Analysis of the Origins of a Cooperative Binding Energy of Dimerization, pp. 711-714
Dudley H. Williams; Alison J. Maguire; Wakako Tsuzuki; Martin S. Westwell

Elucidation of the Chain Conformation in a Glassy Polyester, PET, by Two-Dimensional NMR, pp. 714-717
K. Schmidt-Rohr; W. Hu; N. Zumbulyadis

Effect of Substrate Strain on Adsorption, pp. 717-720
M. Gsell; P. Jakob; D. Menzel

Micromechanical "Trampoline" Magnetometers for Use in Large Pulsed Magnetic Fields, pp. 720-722
V. Aksyuk; F. F. Balakirev; G. S. Boebinger; P. L. Gammel; R. C. Haddon; D. J. Bishop

Reductive Dechlorination of DDE to DDMU in Marine Sediment Microcosms, pp. 722-724
John F. Quensen III; Sherry A. Mueller; Mahendra K. Jain; James M. Tiedje

Deep-Sea Coral Evidence for Rapid Change in Ventilation of the Deep North Atlantic 15,400 Years Ago, pp. 725-728
Jess F. Adkins; Hai Cheng; Edward A. Boyle; Ellen R. M. Druffel; R. Lawrence Edwards

Local Orbital Forcing of Antarctic Climate Change During the Last Interglacial, pp. 728-730
Seong-Joong Kim; Thomas J. Crowley; Achim Stössel

Cope's Rule and the Dynamics of Body Mass Evolution in North American Fossil Mammals, pp. 731-734
John Alroy

Proteolytic Inactivation of MAP-Kinase-Kinase by Anthrax Lethal Factor, pp. 734-737
Nicholas S. Duesbery; Craig P. Webb; Stephen H. Leppla; Valery M. Gordon; Kurt R. Klimpel; Terry D. Copeland; Natalie G. Ahn; Marianne K. Oskarsson; Kenji Fukasawa; Ken D. Paull; George F. Vande Woude

Disruption of Splicing Regulated by a CUG-Binding Protein in Myotonic Dystrophy, pp. 737-741
Anne V. Philips; Lubov T. Timchenko; Thomas A. Cooper

Yeast Ku as a Regulator of Chromosomal DNA End Structure, pp. 741-744
Serge Gravel; Michel Larrivée; Pascale Labrecque; Raymund J. Wellinger

Modulation of Diversity by Grazing and Mowing in Native Tallgrass Prairie, pp. 745-747
Scott L. Collins; Alan K. Knapp; John M. Briggs; John M. Blair; Ernest M. Steinauer

Anterior Cingulate Cortex, Error Detection, and the Online Monitoring of Performance, pp. 747-749
Cameron S. Carter; Todd S. Braver; Deanna M. Barch; Matthew M. Botvinick; Douglas Noll; Jonathan D. Cohen

Actin Mutations in Dilated Cardiomyopathy, a Heritable Form of Heart Failure, pp. 750-752
Timothy M. Olson; Virginia V. Michels; Stephen N. Thibodeau; Yin-Shan Tai; Mark T. Keating

Ribonuclease P Protein Structure: Evolutionary Origins in the Translational Apparatus, pp. 752-755
Travis Stams; S. Niranjanakumari; Carol A. Fierke; David W. Christianson

Back Matter (33 pp.)

Previous Issue: New Series, Vol. 280, No. 5363, Apr. 24, 1998
Next Issue: New Series, Vol. 280, No. 5365, May 8, 1998

Previous Issue: New Series, Vol. 280, No. 5364, May 1, 1998
Next Issue: New Series, Vol. 280, No. 5366, May 15, 1998

Front Matter (37 pp.)
Netwatch, p. 795
Jocelyn Kaiser

Editorial: Science Roadmaps, p. 803
Robert Galvin

Letters

AIDS Vaccine Development, pp. 803+805-807
Moises Agosto; Jon Allan; Constance Benson; Edward A. Berger; Robert Blumenthal; Dennis Burton; Janice Clements; John Coffin; Ruth Connor; Bryan Cullen; Ronald Desrosiers; Dimiter Dimitrov; Robert Doms; Michael Emerman; Mark Feinberg; Patricia Fultz; Craig Gerard; Gregg Gonsalves; Ashley Haase; Nancy Haigwood; Vanessa Hirsch; David Ho; James A. Hoxie; Shiu-Lok Hu; Eric Hunter; Philip Johnson; Paul Akio Kawata; Bette Korber; Carla Kuiken; Gerald H. Learn; Thomas Leitner; George Lewis; Derek Link; Jeremy Luban; Katherine Luzuriaga; Michael Malim; Preston Marx; J. M. McCune; David Montefiori; John Moore; Casey Morrow; Donald Mosier; Mark Muesing; Douglas Nixon; Jack Nunberg; Julie Overbaugh; Paul Parren; Vincente Planelles; Melissa Pope; David N. Posnett; Robert Siliciano; Ralph Steinman; Mario Stevenson; Ronald Swanstrom; Bruce D. Walker; Steven Wolinsky; Daniel Zingale; Jean-Paul Lévy

Ecological Science and Statistical Paradigms, p. 807
Emery Roe

On "The Science of Substance Abuse", pp. 807-808
Gene M. Heyman

The Korean DMZ: A Fragile Ecosystem, pp. 808-809
Kun H. John

ScienceScope, p. 813
Constance Holden

News and Comment

DNA Sequencers' Trial by Fire, pp. 814-817
Elizabeth Pennisi

Requiem for a Heavyweight at Meeting on Fusion Reactors, pp. 818-819
James Glanz

Euphoria Fades as Threats Emerge, pp. 819-820
Andrew Lawler

Location Dispute Freezes Arctic Facility, p. 820
Jeffrey Mervis

Reformer Named Science Minister, p. 821
Richard Stone

Plan Would Link, Bolster Health Research, pp. 821-822
Wayne Kondro

EU Moves to Decrease the Gender Gap, p. 822
Nigel Williams

Research News

Recipe for a Kilogram, pp. 823-824
David Kestenbaum

AIDS Researchers Negotiate Tricky Slopes of Science, pp. 825-826
Michael Balter

Navigating Chernobyl's Deadly Maze, pp. 826-827
Joseph Alper

Writing, Speech Separated in Split Brain, p. 827
Evelyn Strauss

Beam Splitter Teases Out Phase Secrets, p. 828
Robert F. Service

A Dusty Ice Age Trigger Looks Too Weak, pp. 828-829
Richard A. Kerr

Random Samples, p. 831
Constance Holden

Essays on Science and Society

A Book For All Seasons, pp. 832-833
James Lovelock

Science's Compass

Policy

Technology, Experimentation, and the Quality of Survey Data, pp. 847-848
David E. Bloom

Books

Get a Life, pp. 849-850
Introduction to Artifical Life.
Christoph Adami

Review author[s]: Richard E. Lenski

Knowledge from the Flies, pp. 850-851
Progress and Prospects in Evolutionary Biology: The Drosophila Model.
Jeffrey R. Powell

Review author[s]: Walter F. Eanes

Research

Xenon's Inside Story, pp. 851-852
Ichiro Kaneoka

The Era of Pathway Quantification, pp. 852-853
Daniel E. Koshland Jr.

Scanning with Ease Through the Far Infrared, p. 854
Richard Temkin

Review

Biodemographic Trajectories of Longevity, pp. 855-860
James W. Vaupel; James R. Carey; Kaare Christensen; Thomas E. Johnson; Anatoli I. Yashin; Niels V. Holm; Ivan A. Iachine; Väinö Kannisto; Aziz A. Khazaeli; Pablo Liedo; Valter D. Longo; Yi Zeng; Kenneth G. Manton; James W. Curtsinger

Research Article

Adolescent Sexual Behavior, Drug Use, and Violence: Increased Reporting with Computer Survey Technology, pp. 867-873
C. F. Turner; L. Ku; S. M. Rogers; L. D. Lindberg; J. H. Pleck; F. L. Sonenstein

Reports

A 100,000-Year Periodicity in the Accretion Rate of Interplanetary Dust, pp. 874-876
Stephen J. Kortenkamp; Stanley F. Dermott

Plutonium-Fission Xenon Found in Earth's Mantle, pp. 877-880
Joachim Kunz; Thomas Staudacher; Claude J. Allègre

Reaction Sequence of Iron Sulfide Minerals in Bacteria and Their Use as Biomarkers, pp. 880-883
Mihály Pósfai; Peter R. Buseck; Dennis A. Bazylinski; Richard B. Frankel

Clams as Recorders of Ocean Ridge Volcanism and Hydrothermal Vent Field Activity, pp. 883-886
Stanley R. Hart; Jerzy Blusztajn

Pressure-Induced Amorphization and Negative Thermal Expansion in ZrW₂O₈, pp. 886-889
C. A. Perottoni; J. A. H. da Jornada

Self-Trapping of Dark Incoherent Light Beams, pp. 889-892
Zhigang Chen; Matthew Mitchell; Mordechai Segev; Tamer H. Coskun; Demetrios N. Christodoulides

Ultrathin Films of a Polyelectrolyte with Layered Architecture, pp. 892-895
A. R. Esker; C. Mengel; G. Wegner

The Biochemical Basis of an All-or-None Cell Fate Switch in Xenopus Oocytes, pp. 895-898
James E. Ferrell Jr.; Eric M. Machleder

Role of Rac1 and Oxygen Radicals in Collagenase-1 Expression Induced by Cell Shape Change, pp. 898-902
Farrah Kheradmand; Erica Werner; Patrice Tremble; Marc Symons; Zena Werb

Modular Organization of Cognitive Systems Masked by Interhemispheric Integration, pp. 902-905
Kathleen Baynes; James C. Eliassen; Helmi L. Lutsep; Michael S. Gazzaniga

Thymocyte Development in the Absence of Pre-T Cell Receptor Extracellular Immunoglobulin Domains, pp. 905-908
Bryan A. Irving; Frederick W. Alt; Nigel Killeen

Replication Checkpoint Enforced by Kinases Cds1 and Chk1, pp. 909-912
Michael N. Boddy; Beth Furnari; Odile Mondesert; Paul Russell

Chaos, Persistence, and Evolution of Strain Structure in Antigenically Diverse Infectious Agents, pp. 912-915
Sunetra Gupta; Neil Ferguson; Roy Anderson

Identification of Non-Heme Diiron Proteins That Catalyze Triple Bond and Epoxy Group Formation, pp. 915-918
Michael Lee; Marit Lenman; Antoni Banaś; Maureen Bafor; Surinder Singh; Michael Schweizer; Ralf Nilsson; Conny Liljenberg; Anders Dahlqvist; Per-Olov Gummeson; Staffan Sjödahl; Allan Green; Sten Stymne

A Role for the AKT1 Potassium Channel in Plant Nutrition, pp. 918-921
Rebecca E. Hirsch; Bryan D. Lewis; Edgar P. Spalding; Michael R. Sussman

Knowing Where and Getting There: A Human Navigation Network, pp. 921-924
Eleanor A. Maguire; Neil Burgess; James G. Donnett; Richard S. J. Frackowiak; Christopher D. Frith; John O'Keefe

Back Matter (44 pp.)

Previous Issue: New Series, Vol. 280, No. 5364, May 1, 1998
Next Issue: New Series, Vol. 280, No. 5366, May 15, 1998

Previous Issue: New Series, Vol. 280, No. 5365, May 8, 1998
Next Issue: New Series, Vol. 280, No. 5367, May 22, 1998

Front Matter (37 pp.)
NetWatch, p. 975
Jocelyn Kaiser

Editorial: Toward a Transparent Federal S&T Budget, p. 983
Jeff Bingaman; Joseph Lieberman

Letters

Haeckel, Embryos, and Evolution, pp. 983+985-986
Michael K. Richardson; James Hanken; Lynne Selwood; Glenda M. Wright; Robert J. Richards; Claude Pieau; Albert Raynaud

Demographic Thinking, p. 986
James W. Vaupel

Bird, Dinosaur Link, pp. 986-987
Kevin Padian

Science in Vietnam, p. 987
Tuan V. Nguyen

A Good Estrogen, pp. 987-988
Victor S. Pribluda; Shawn J. Green

Causal Systems in Ecology, pp. 988-989
Joel H. Reynolds

Corrections and Clarifications: Australian Partnerships: New Life for Research Centers, p. 989
Corrections and Clarifications: Requirement of Ras-GTP-Raf Complexes for Activation of Raf-1 by Protein Kinase C, p. 989
Corrections and Clarifications: Does Public Funding Corrupt?, p. 989
Corrections and Clarifications: Bioprospecting: Lawsuit Targets Yellowstone Bug Deal, p. 989
Corrections and Clarifications: Has French AIDS Research Stumbled, p. 989
ScienceScope, p. 993
Constance Holden

News and Comment

Hubris and the Human Genome, pp. 994-995
Eliot Marshall; Elizabeth Pennisi

Picking Up the Pace of Sequencing, p. 995
Robert F. Service

The Power of The Front Page of the New York Times, pp. 996-997
Eliot Marshall

Mars 2001 Mission Hits the Wall, p. 998
Oliver Morton

State Department Sees S&T Weaknesses, pp. 998-999
Andrew Lawler

German Biotechs Form Gene Venture, pp. 999-1000
Robert Koenig

Japan Urged to Drop Short-Term Goal, p. 1000
Dennis Normile

Allen Roses: From 'Street Fighter' to Corporate Insider, pp. 1001-1004
Eliot Marshall

Research News

Probing the Biology of Emotion, pp. 1005-1007
Christine Mlot

Biggest Extinction Looks Catastrophic, p. 1007
Richard A. Kerr

Exploding Stars Flash New Bulletins from Distant Universe, pp. 1008-1009
James Glanz

On the Trail of Supercharged Hydrogen, p. 1009
Alexander Hellemans

New Probes Open Windows on Gene Expression, and More, pp. 1010-1011
Robert F. Service

Random Samples, p. 1013
Constance Holden

Essays on Science and Society

Science as a Craft Industry, pp. 1014-1015
Freeman J. Dyson

Science's Compass

Policy

Interpretation of International Test Score Comparisons, pp. 1030-1031
Iris C. Rotberg

Books

Early Neuro Networks, pp. 1032-1033
The History of Neuroscience in Autobiography. Vol. I.
Larry R. Squire

Review author[s]: Martha Constantine-Paton

Research

A New Spin on Hydrothermal Plumes, pp. 1034-1035
Kevin G. Speer

The Expanding Role of Cell Cycle Regulators, pp. 1035-1036
Tyler Jacks; Robert A. Weinberg

Landscaping the Cancer Terrain, pp. 1036-1037
Kenneth W. Kinzler; Bert Vogelstein

Research Article

U/Pb Zircon Geochronology and Tempo of the End-Permian Mass Extinction, pp. 1039-1045
S. A. Bowring; D. H. Erwin; Y. G. Jin; M. W. Martin; K. Davidek; W. Wang

Reports

Chemical Amplification: Continuous-Flow PCR on a Chip, pp. 1046-1048
Martin U. Kopp; Andrew J. de Mello; Andreas Manz

Predatory Dinosaur Remains from Madagascar: Implications for the Cretaceous Biogeography of Gondwana, pp. 1048-1051
Scott D. Sampson; Lawrence M. Witmer; Catherine A. Forster; David W. Krause; Patrick M. O'Connor; Peter Dodson; Florent Ravoavy

Tracking the Evolution of a Hydrothermal Event Plume with a RAFOS Neutrally Buoyant Drifter, pp. 1052-1055
John E. Lupton; Edward T. Baker; Newell Garfield; Gary J. Massoth; Richard A. Feely; James P. Cowen; Ronald R. Greene; Thomas A. Rago

Earthquakes on Dipping Faults: The Effects of Broken Symmetry, pp. 1055-1059
David D. Oglesby; Ralph J. Archuleta; Stefan B. Nielsen

Percolation of Core Melts at Lower Mantle Conditions, pp. 1059-1061
M. C. Shannon; C. B. Agee

Localized Reconnection in the Near Jovian Magnetotail, pp. 1061-1064
C. T. Russell; K. K. Khurana; D. E. Huddleston; M. G. Kivelson

Ferromagnetism in LaFeO₃-LaCrO₃ Superlattices, pp. 1064-1066
Kenji Ueda; Hitoshi Tabata; Tomoji Kawai

Inducible Repair of Thymine Glycol Detected by an Ultrasensitive Assay for DNA Damage, pp. 1066-1069
X. Chris Le; James Z. Xing; Jane Lee; Steven A. Leadon; Michael Weinfeld

Inhibitory Function of p21 ^Cip1/WAF1 in Differentiation of Primary Mouse Keratinocytes Independent of Cell Cycle Control, pp. 1069-1072
Ferdinando Di Cunto; Gabrielle Topley; Enzo Calautti; Jimmy Hsiao; Lydia Ong; Prem K. Seth; G. Paolo Dotto

Genetic Evaluation of Suspected Cases of Transient HIV-1 Infection of Infants, pp. 1073-1077
Lisa M. Frenkel; James I. Mullins; Gerald H. Learn; Laura Manns-Arcuino; Belinda L. Herring; Marcia L. Kalish; Richard W. Steketee; Donald M. Thea; Joan E. Nichols; Shan-Lu Liu; Abdallah Harmache; Xi He; David Muthui; Anup Madan; Leroy Hood; Ashley T. Haase; Mary Zupancic; Katherine Staskus; Steven Wolinsky; Paul Krogstad; JiaQi Zhao; Irvin Chen; Richard Koup; David Ho; Bette Korber; Raymond J. Apple; Robert W. Coombs; Savita Pahwa; Norbert J. Roberts, Jr.

Large-Scale Identification, Mapping, and Genotyping of Single-Nucleotide Polymorphisms in the Human Genome, pp. 1077-1082
David G. Wang; Jian-Bing Fan; Chia-Jen Siao; Anthony Berno; Peter Young; Ron Sapolsky; Ghassan Ghandour; Nancy Perkins; Ellen Winchester; Jessica Spencer; Leonid Kruglyak; Lincoln Stein; Linda Hsie; Thodoros Topaloglou; Earl Hubbell; Elizabeth Robinson; Michael Mittmann; Macdonald S. Morris; Naiping Shen; Dan Kilburn; John Rioux; Chad Nusbaum; Steve Rozen; Thomas J. Hudson; Robert Lipshutz; Mark Chee; Eric S. Lander

RasGRP, a Ras Guanyl Nucleotide-Releasing Protein with Calcium- and Diacylglycerol-Binding Motifs, pp. 1082-1086
Julius O. Ebinu; Drell A. Bottorff; Edmond Y. W. Chan; Stacey L. Stang; Robert J. Dunn; James C. Stone

Mutations in the SMAD4/DPC4 Gene in Juvenile Polyposis, pp. 1086-1088
James R. Howe; Stina Roth; John C. Ringold; Robert W. Summers; Heikki J. Järvinen; Pertti Sistonen; Ian P. M. Tomlinson; Richard S. Houlston; Steve Bevan; Frank A. Mitros; Edwin M. Stone; Lauri A. Aaltonen

Requirement for Atm in Ionizing Radiation-Induced Cell Death in the Developing Central Nervous System, pp. 1089-1091
Karl-Heinz Herzog; Miriam J. Chong; Manuela Kapsetaki; James I. Morgan; Peter J. McKinnon

COI1: An Arabidopsis Gene Required for Jasmonate-Regulated Defense and Fertility, pp. 1091-1094
Dao-Xin Xie; Bart F. Feys; Sarah James; Manuela Nieto-Rostro; John G. Turner

Tech.Sight

Predicting Properties from Scratch, pp. 1099-1100
Gerbrand Ceder

Automating a Mouse, p. 1101
Robert Sikorski; Richard Peters

Zeptomolar Damage, pp. 1101-1102
Richard Peters; Robert Sikorski

Internet Connectivity, p. 1102
Robert Sikorski; Richard Peters

Back Matter (54 pp.)

Previous Issue: New Series, Vol. 280, No. 5365, May 8, 1998
Next Issue: New Series, Vol. 280, No. 5367, May 22, 1998

Previous Issue: New Series, Vol. 280, No. 5366, May 15, 1998
Next Issue: New Series, Vol. 280, No. 5368, May 29, 1998

Front Matter (26 pp.)
NetWatch, p. 1163
Jocelyn Kaiser

Editorial: Space Policy in a Vacuum, p. 1171
David L. Bodde

Letters

Radiocarbon Dates of Kennewick Man, pp. 1171+1173
R. E. Taylor; Donna L. Kirner; John R. Southon; James C. Chatters

Science and the Web, pp. 1173-1174
Y. Poumay

Research on Auditory Cortex Plasticity, p. 1174
Norman M. Weinberger; Jonathan S. Bakin; Michael Kilgard; Michael Merzenich

One Infant's Memory of Oedipus, pp. 1174-1177
Richard A. Littman; Victor H. Denenberg; Peter W. Jusczyk

Corrections and Clarifications: Scientific Growth Faces Fiscal Crisis, p. 1177
Corrections and Clarifications: Results from the Mars Pathfinder Camera, p. 1177
ScienceScope, p. 1181
Constance Holden

News and Comment

An Institute for Planet Earth, pp. 1182-1185
Gretchen Vogel

Funders Reassure Genome Sequencers, p. 1185
Elizabeth Pennisi

Groups Vie for Space Chimp Colony, p. 1186
David Kestenbaum

Elephantine Gift Stirs Museum Debate, pp. 1186-1187
Eliot Marshall

WHO's Slow Road to Funding Reform, pp. 1187-1188
Lisa Schlein

EU Ends 10-Year Battle Over Biopatents, p. 1188
Helen Gavaghan

Experts Search for Details After Indian Nuclear Tests, p. 1189
Pallava Bagla; Andrew Lawler

Taiwan Trolls for U.S. Firms to Help It Create an Industry, p. 1190
Bruce Agnew

Research News

Building a Better Aspirin, pp. 1191-1192
Elizabeth Pennisi

The Fastest Counter of the Smallest Beans, p. 1193
Robert F. Service

A Neutron Star That Got Revved Up, pp. 1193-1194
James Glanz

Can Great Quakes Extend Their Reach?, pp. 1194-1195
Richard A. Kerr

Ecosystem 'Engineers' Shape Habitats for Other Species, pp. 1195-1196
Joseph Alper

Antibodies Stage a Comeback In Cancer Treatment, pp. 1196-1197
Steven Dickman

Random Samples, p. 1199
Constance Holden

Essays on Science and Society

Science and Morality, pp. 1200-1201
Edward Teller

Science's Compass

Books

A Sense of Place, p. 1209
Water, Culture, and Power. Local Struggles in a Global Context.
John M. Donahue; Barbara Rose Johnston

Review author[s]: Robert Gottlieb

Water Ordering Landscapes, p. 1210
Fractal River Basins. Chance and Self-Organization.
Ignacio Rodriguez-Iturbe; Andrea Rinaldo

Review author[s]: Anastasios A. Tsonis

Research

The Salt of Europa, pp. 1211-1212
Jeffrey S. Kargel

Kinases and Phosphatases-A Marriage is Consummated, pp. 1212-1213
Ernst Hafen

Quantum Trick Shots, p. 1213
David Voss

Reports

The MELT Experiment

Imaging the Deep Seismic Structure Beneath a Mid-Ocean Ridge: The MELT Experiment, pp. 1215-1218
The MELT Seismic Team

Off-Axis Crustal Thickness Across and Along the East Pacific Rise Within the MELT Area, pp. 1218-1221
J. Pablo Canales; Robert S. Detrick; Sara Bazin; Alistair J. Harding; John A. Orcutt

Shipboard Geophysical Indications of Asymmetry and Melt Production Beneath the East Pacific Rise Near the MELT Experiment, pp. 1221-1224
Daniel S. Scheirer; Donald W. Forsyth; Marie-Hélène Cormier; Ken C. Macdonald

Mantle Seismic Structure Beneath the MELT Region of the East Pacific Rise from P and S Wave Tomography, pp. 1224-1227
Douglas R. Toomey; William S. D. Wilcock; Sean C. Solomon; William C. Hammond; John A. Orcutt

Structure of the Upper Mantle Under the EPR from Waveform Inversion of Regional Events, pp. 1227-1229
Spahr C. Webb; Donald W. Forsyth

Shear-Wave Splitting and Implications for Mantle Flow Beneath the MELT Region of the East Pacific Rise, pp. 1230-1232
Cecily J. Wolfe; Sean C. Solomon

Mantle Discontinuity Structure Beneath the Southern East Pacific Rise from P-to-S Converted Phases, pp. 1232-1235
Yang Shen; Anne F. Sheehan; Kenneth G. Dueker; Catherine de Groot-Hedlin; Hersh Gilbert

Phase Velocities of Rayleigh Waves in the MELT Experiment on the East Pacific Rise, pp. 1235-1238
Donald W. Forsyth; Spahr C. Webb; LeRoy M. Dorman; Yang Shen

The Radio-Frequency Single-Electron Transistor (RF-SET): A Fast and Ultrasensitive Electrometer, pp. 1238-1242
R. J. Schoelkopf; P. Wahlgren; A. A. Kozhevnikov; P. Delsing; D. E. Prober

Salts on Europa's Surface Detected by Galileo's Near Infrared Mapping Spectrometer, pp. 1242-1245
T. B. McCord; G. B. Hansen; F. P. Fanale; R. W. Carlson; D. L. Matson; T. V. Johnson; W. D. Smythe; J. K. Crowley; P. D. Martin; A. Ocampo; C. A. Hibbitts; J. C. Granahan; NIMS Team

Viscosity of Oceanic Asthenosphere Inferred from Remote Triggering of Earthquakes, pp. 1245-1249
Fred F. Pollitz; Roland Bürgmann; Barbara Romanowicz

Geochemical Evidence for a Comet Shower in the Late Eocene, pp. 1250-1253
K. A. Farley; A. Montanari; E. M. Shoemaker; C. S. Shoemaker

Fullerene Pipes, pp. 1253-1256
Jie Liu; Andrew G. Rinzler; Hongjie Dai; Jason H. Hafner; R. Kelley Bradley; Peter J. Boul; Adrian Lu; Terry Iverson; Konstantin Shelimov; Chad B. Huffman; Fernando Rodriguez-Macias; Young-Seok Shon; T. Randall Lee; Daniel T. Colbert; Richard E. Smalley

Cloned Transgenic Calves Produced from Nonquiescent Fetal Fibroblasts, pp. 1256-1258
Jose B. Cibelli; Steve L. Stice; Paul J. Golueke; Jeff J. Kane; Joseph Jerry; Cathy Blackwell; F. Abel Ponce de León; James M. Robl

A Signaling Complex of Ca ²⁺ -Calmodulin-Dependent Protein Kinase IV and Protein Phosphatase 2A, pp. 1258-1261
Ryan S. Westphal; Kristin A. Anderson; Anthony R. Means; Brian E. Wadzinski

Catalytic Activation of the Phosphatase MKP-3 by ERK2 Mitogen-Activated Protein Kinase, pp. 1262-1265
Montserrat Camps; Anthony Nichols; Corine Gillieron; Bruno Antonsson; Marco Muda; Christian Chabert; Ursula Boschert; Steve Arkinstall

Requirement for γδ T Cells in Allergic Airway Inflammation, pp. 1265-1267
Claudia Zuany-Amorim; Claude Ruffié; Solomon Hailé; B. Boris Vargaftig; Pablo Pereira; Marina Pretolani

Aspirin-like Molecules that Covalently Inactivate Cyclooxygenase-2, pp. 1268-1270
Amit S. Kalgutkar; Brenda C. Crews; Scott W. Rowlinson; Carlos Garner; Karen Seibert; Lawrence J. Marnett

Molecular Basis for Interactions of G Protein βγ Subunits with Effectors, pp. 1271-1274
Carolyn E. Ford; Nikolai P. Skiba; Hyunsu; Bae; Yehia Daaka; Eitan Reuveny; Lee R. Shekter; Ramon Rosal; Gezhi Weng; Chii-Shen Yang; Ravi Iyengar; Richard J. Miller; Lily Y. Jan; Robert J. Lefkowitz; Heidi E. Hamm

Distinct WNT Pathways Regulating AER Formation and Dorsoventral Polarity in the Chick Limb Bud, pp. 1274-1277
Mineko Kengaku; Javier Capdevila; Concepción Rodriguez-Esteban; Jennifer De La Peña; Randy L. Johnson; Juan Carlos Izpisúa Belmonte; Clifford J. Tabin

X-ray Crystal Structure of C3d: A C3 Fragment and Ligand for Complement Receptor 2, pp. 1277-1281
Bhushan Nagar; Russell G. Jones; Russell J. Diefenbach; David E. Isenman; James M. Rini

Back Matter (31 pp.)

Previous Issue: New Series, Vol. 280, No. 5366, May 15, 1998
Next Issue: New Series, Vol. 280, No. 5368, May 29, 1998

Previous Issue: New Series, Vol. 280, No. 5367, May 22, 1998
Next Issue: New Series, Vol. 280, No. 5369, Jun. 5, 1998

Front Matter (30 pp.)
NetWatch, p. 1319
Jocelyn Kaiser

Editorial: Challenges for European Biology, p. 1327
Fotis C. Kafatos

Letters

The Ethics of AIDS Vaccine Trials, pp. 1327+1329-1331
Jonathan M. Mann; Deborah Zion; Cheryl Cox Macpherson; Barry R. Bloom

Corrections and Clarifications: Budding Yeast Cdc20: A Target of the Spindle Checkpoint, p. 1331
ScienceScope, p. 1335
Constance Holden

News and Comment

A New Initiative for Russian Science, pp. 1336-1337
Richard Stone

'First Light' for Giant Sky Survey, pp. 1337-1338
James Glanz

Astrobiology Institute Picks Partners, p. 1338
Andrew Lawler

Ready for Takeoff, Antimatter Experiment Takes Some Flak, p. 1339
Meher Antia

Smithsonian Field Station Gets the Boot, p. 1340
Joseph Alper

Japan Law Fosters Academic Patents, pp. 1340-1341
Dennis Normile

Panel Issues Plea to Boost FDA Research, p. 1341
Eliot Marshall

Aboriginal Groups Warm to Studies of Early Australians, pp. 1342-1343
Elizabeth Finkel

Euro Networks Aim to Train Postdocs, Build a Community, p. 1344
Judy Redfearn

Research News

Solving the Brain's Energy Crisis, pp. 1345-1347
Ann Gibbons

Taiwan, U.S. Team Up to Chase Shadows, p. 1347
Peter Weiss

Transmuting Light Into X-rays, p. 1348
David Kestenbaum

New Clues to Alcoholism Risk, pp. 1348-1349
Constance Holden

Temperature Rise Could Squeeze Salmon, p. 1349
Nigel Williams

Growing Joints Use Their Noggins, p. 1350
Steven Dickman

New Method Churns Out TB Mutants, pp. 1350-1351
Carol Potera

Young Ages for Australian Rock Art, p. 1351
Ann Gibbons

Random Samples, p. 1353
Constance Holden

Essays on Science and Society

The Shoulders of Giants, pp. 1354-1355
Dara Horn

Regulation of Body Weight

[Introduction], p. 1363
Paula A. Kiberstis; Jean Marx

News

Obesity: How Big a Problem?, pp. 1364-1367
Ingrid Wickelgren

As Obesity Rates Rise, Experts Struggle to Explain Why, pp. 1367-1368
Gary Taubes

Uncoupling Proteins Provide New Clue to Obesity's Causes, pp. 1369-1370
Trisha Gura

Environmental Contributions to the Obesity Epidemic, pp. 1371-1374
James O. Hill; John C. Peters

The Search for Human Obesity Genes, pp. 1374-1377
Anthony G. Comuzzie; David B. Allison

Signals That Regulate Food Intake and Energy Homeostasis, pp. 1378-1383
Stephen C. Woods; Randy J. Seeley; Daniel Porte Jr.; Michael W. Schwartz

Strategies and Potential Molecular Targets for Obesity Treatment, pp. 1383-1387
L. Arthur Campfield; Françoise J. Smith; Paul Burn

Eating Disorders: Progress and Problems, pp. 1387-1390
B. Timothy Walsh; Michael J. Devlin

Science's Compass

Policy

The Terrestrial Carbon Cycle: Implications for the Kyoto Protocol, pp. 1393-1394
IGBP Terrestrial Carbon Working Group

Books

Unification Not Proved, p. 1395
Consilience. The Unity of Knowledge.
Edward O. Wilson

Review author[s]: John Dupré

Boundaries Not Established, pp. 1396-1397
Impossibility. The Limits of Science and the Science of Limits.
John Barrow

Review author[s]: Steve Fuller

Research

The Case of the Curved Universe: Open, Closed, or Flat?, pp. 1397-1398
Marc Kamionkowski

A Little Hot Dark Matter Matters, pp. 1398-1400
Joel R. Primack

Cloning for Profit, pp. 1400-1401
Gary B. Anderson; George E. Seidel

What's the Best Sound?, pp. 1402-1403
Eric D. Young

More Deafness Genes, p. 1403
Karen P. Steel; Steve D. M. Brown

Research Article

Extracting Primordial Density Fluctuations, pp. 1405-1411
Eric Gawiser; Joseph Silk

Reports

Phase-Matched Generation of Coherent Soft X-rays, pp. 1412-1415
Andy Rundquist; Charles G. Durfee III; Zenghu Chang; Catherine Herne; Sterling Backus; Margaret M. Murnane; Henry C. Kapteyn

Electrical Conductivity of Olivine, Wadsleyite, and Ringwoodite Under Upper-Mantle Conditions, pp. 1415-1418
Yousheng Xu; Brent T. Poe; Thomas J. Shankland; David C. Rubie

In situ Discovery of Graphite with Interstellar Isotopic Signatures in a Chondrule-Free Clast in an L3 Chondrite, pp. 1418-1420
S. Mostefaoui; P. Hoppe; A. El Goresy

Eclogitic Diamond Formation at Jwaneng: No Room for a Recycled Component, pp. 1421-1424
Pierre Cartigny; Jeffrey W. Harris; Marc Javoy

Multiple-Step Melting in Two-Dimensional Hexatic Liquid-Crystal Films, pp. 1424-1426
Chia-Fu Chou; Anjun J. Jin; S. W. Hui; C. C. Huang; John T. Ho

Helical Superstructures from Charged Poly(styrene)-Poly(isocyanodipeptide) Block Copolymers, pp. 1427-1430
Jeroen J. L. M. Cornelissen; Matthias Fischer; Nico A. J. M. Sommerdijk; Roeland J. M. Nolte

Identification of Water Ice on the Centaur 1997 CU26, pp. 1430-1432
Robert H. Brown; Dale P. Cruikshank; Yvonne Pendleton; Glenn J. Veeder

Impairment of Mycobacterial Immunity in Human Interleukin-12 Receptor Deficiency, pp. 1432-1435
Frédéric Altare; Anne Durandy; David Lammas; Jean-François Emile; Salma Lamhamedi; Françoise Le Deist; Pam Drysdale; Emmanuelle Jouanguy; Rainer Döffinger; Françoise Bernaudin; Olle Jeppsson; Jared A. Gollob; Edgar Meinl; Antony W. Segal; Alain Fischer; Dinakantha Kumararatne; Jean-Laurent Casanova

Severe Mycobacterial and Salmonella Infections in Interleukin-12 Receptor- Deficient Patients, pp. 1435-1438
Rolien de Jong; Frédéric Altare; Inez-Anne Haagen; Diënne G. Elferink; Tjitske de Boer; Peter J. C. van Breda Vriesman; Peter J. Kabel; Johannes M. T. Draaisma; Jaap T. van Dissel; Frank P. Kroon; Jean-Laurent Casanova; Tom H. M. Ottenhoff

Optimizing Sound Features for Cortical Neurons, pp. 1439-1443
R. Christopher deCharms; David T. Blake; Michael M. Merzenich

Correction of Deafness in shaker-2 Mice by an Unconventional Myosin in a BAC Transgene, pp. 1444-1447
Frank J. Probst; Robert A. Fridell; Yehoash Raphael; Thomas L. Saunders; Aihui Wang; Yong Liang; Robert J. Morell; Jeffrey W. Touchman; Robert H. Lyons; Konrad Noben-Trauth; Thomas B. Friedman; Sally A. Camper

Association of Unconventional Myosin MYO15 Mutations with Human Nonsyndromic Deafness DFNB3, pp. 1447-1451
Aihui Wang; Yong Liang; Robert A. Fridell; Frank J. Probst; Edward R. Wilcox; Jeffrey W. Touchman; Cynthia C. Morton; Robert J. Morell; Konrad Noben-Trauth; Sally A. Camper; Thomas B. Friedman

Continuity in Evolution: On the Nature of Transitions, pp. 1451-1455
Walter Fontana; Peter Schuster

Noggin, Cartilage Morphogenesis, and Joint Formation in the Mammalian Skeleton, pp. 1455-1457
Lisa J. Brunet; Jill A. McMahon; Andrew P. McMahon; Richard M. Harland

AAAS News and Notes, pp. 1460-1463
Ellen Cooper

Back Matter (29 pp.)

Previous Issue: New Series, Vol. 280, No. 5367, May 22, 1998
Next Issue: New Series, Vol. 280, No. 5369, Jun. 5, 1998

Previous Issue: New Series, Vol. 280, No. 5368, May 29, 1998
Next Issue: New Series, Vol. 280, No. 5370, Jun. 12, 1998

Front Matter (24 pp.)
NetWatch, p. 1499
Jocelyn Kaiser

Editorial: It's not Rocket Science-But it can Save Lives, p. 1507
Barbara R. Jasny; Floyd E. Bloom

Letters

Wildlife Conservation in Kenya, pp. 1507+1509-1511
David Western; Kurt Benirschke; Joel Berger; Daniel H. Janzen; Winnie Hallwachs; Gary K. Meffe; Norman Myers; William D. Newmark; David S. Woodruff; Jack Bradbury; Peter H. Raven; Colin Norman

ScienceScope, p. 1515
Constance Holden

News and Comment

NIH Plans Bioengineering Initiative, pp. 1516-1518
Bruce Agnew

Ousted Kenya Parks Head Gets Job Back, pp. 1518-1519
Constance Holden

Peace Process Set to Boost Collaboration, p. 1519
Nigel Williams

New Budget Boosts 'Secret' Science, p. 1520
Pallava Bagla

Biggest Telescope Opens One Eye, p. 1520
Govert Schilling

New Rules on Human Subjects could End Debate in Canada, p. 1521
Wayne Kondro

Research News

Cosmos in a Computer, pp. 1522-1523
James Glanz

Tau Protein Mutations Confirmed as Neuron Killers, pp. 1524-1525
Gretchen Vogel

Old, Old Skull has a New Look, p. 1525
Ann Gibbons

A Giant Snare for Monopoles, p. 1526
David Kestenbaum

Putting Antimatter on the Scales, p. 1526
Alexander Hellemans

Yellowstone Rising Again from Ashes of Devastating Fires, pp. 1527-1528
Richard Stone

One-Eyed Animals Implicate Cholesterol in Development, pp. 1528-1529
Evelyn Strauss

Random Samples, p. 1531
Constance Holden

Essays on Science and Society

Presidents, Experts, and Asteroids, pp. 1532-1533
Arthur Clarke

Science's Compass

Policy

Shotgun Sequencing of the Human Genome, pp. 1540-1542
J. Craig Venter; Mark D. Adams; Granger G. Sutton; Anthony R. Kerlavage; Hamilton O. Smith; Michael Hunkapiller

Books

Palaeobiography, pp. 1542-1543
Life. A Natural History of the First Four Billion Years of Life on Earth.
Richard Fortey

Review author[s]: Paul Copper

Not Noticed by Darwin?, p. 1543
Induced Responses to Herbivory.
Richard Karban; Ian T. Baldwin

Review author[s]: Deane Bowers

Research

Geometrical Shaping of Microlaser Emission Patterns, pp. 1544-1545
Erich Gornik

Deuteronomy?: A Puzzle of Deuterium and Oxygen on Mars, pp. 1545-1546
Yuk L. Yung; David M. Kass

Glutamate Receptor Activation: A Four-Step Program, pp. 1547-1548
Christopher Miller

An End in the Beginning, pp. 1548-1549
Jay Dunlap

Review

Dynamics of Glasses and Glass-Forming Liquids Studied by Inelastic X-ray Scattering, pp. 1550-1555
Francesco Sette; Michael H. Krisch; Claudio Masciovecchio; Giancarlo Ruocco; Giulio Monaco

Research Articles

High-Power Directional Emission from Microlasers with Chaotic Resonators, pp. 1556-1564
Claire Gmachl; Federico Capasso; E. E. Narimanov; Jens U. Nöckel; A. Douglas Stone; Jérôme Faist; Deborah L. Sivco; Alfred Y. Cho

Role of the CLOCK Protein in the Mammalian Circadian Mechanism, pp. 1564-1569
Nicholas Gekakis; David Staknis; Hubert B. Nguyen; Fred C. Davis; Lisa D. Wilsbacher; David P. King; Joseph S. Takahashi; Charles J. Weitz

Reports

Coupled ¹⁸⁶ Os and ¹⁸⁷ Os Evidence for Core-Mantle Interaction, pp. 1570-1573
Alan D. Brandon; Richard J. Walker; John W. Morgan; Marc D. Norman; Hazel M. Prichard

Distribution of Rock, Metals, and Ices in Callisto, pp. 1573-1576
J. D. Anderson; G. Schubert; R. A. Jacobson; E. L. Lau; W. B. Moore; W. L. Sjogren

Detection of Atomic Deuterium in the Upper Atmosphere of Mars, pp. 1576-1580
Vladimir A. Krasnopolsky; Michael J. Mumma; G. Randall Gladstone

Atmosphere-Surface Interactions on Mars: Δ ¹⁷ O Measurements of Carbonate from ALH 84001, pp. 1580-1582
James Farquhar; Mark H. Thiemens; Teresa Jackson

Localization of Metastable Atom Beams with Optical Standing Waves: Nanolithography at the Heisenberg Limit, pp. 1583-1586
K. S. Johnson; J. H. Thywissen; N. H. Dekker; K. K. Berggren; A. P. Chu; R. Younkin; M. Prentiss

Silacalix-[n]-Phosphaarenes: Macrocyclic Ligands Based on Dicoordinate Phosphorus Centers, pp. 1587-1589
Narcis Avarvari; Nicolas Mézailles; Louis Ricard; Pascal Le Floch; François Mathey

High-T_c Superconductors in the Two-Dimensional Limit: [(Py-C_nH _2n+1 )₂Hgl₄]-Bi₂Sr₂Ca _m-1 Cu_mO_y (m= 1 and 2), pp. 1589-1592
Jin-Ho Choy; Soon-Jae Kwon; Gyeong-Su Park

Ribozyme-Mediated Repair of Sickle β-Globin mRNAs in Erythrocyte Precursors, pp. 1593-1596
Ning Lan; Richard P. Howrey; Seong-Wook Lee; Clayton A. Smith; Bruce A. Sullenger

The Tetrameric Structure of a Glutamate Receptor Channel, pp. 1596-1599
Christian Rosenmund; Yael Stern-Bach; Charles F. Stevens

Closing the Circadian Loop: CLOCK-Induced Transcription of Its Own Inhibitors per and tim, pp. 1599-1603
Thomas K. Darlington; Karen Wager-Smith; M. Fernanda Ceriani; David Staknis; Nicholas Gekakis; Thomas D. L. Steeves; Charles J. Weitz; Joseph S. Takahashi; Steve A. Kay

Teratogen-Mediated Inhibition of Target Tissue Response to Shh Signaling, pp. 1603-1607
Michael K. Cooper; Jeffery A. Porter; Keith E. Young; Philip A. Beachy

Inhibition of a Mycobacterium tuberculosis β-Ketoacyl ACP Synthase by Isoniazid, pp. 1607-1610
Khisimuzi Mdluli; Richard A. Slayden; YaQi Zhu; Srinivas Ramaswamy; Xi Pan; David Mead; Deborah D. Crane; James M. Musser; Clifton E. Barry III

Axonal Swellings and Degeneration in Mice Lacking the Major Proteolipid of Myelin, pp. 1610-1613
Ian Griffiths; Matthias Klugmann; Thomas Anderson; Donald Yool; Christine Thomson; Markus H. Schwab; Armin Schneider; Frank Zimmermann; Mailise McCulloch; Nancy Nadon; Klaus-Armin Nave

Inhibition of Cell Migration, Spreading, and Focal Adhesions by Tumor Suppressor PTEN, pp. 1614-1617
Masahito Tamura; Jianguo Gu; Kazue Matsumoto; Shin-ichi Aota; Ramon Parsons; Kenneth M. Yamada

Entry of Alphaherpesviruses Mediated by Poliovirus Receptor-Related Protein 1 and Poliovirus Receptor, pp. 1618-1620
Robert J. Geraghty; Claude Krummenacher; Gary H. Cohen; Roselyn J. Eisenberg; Patricia G. Spear

Back Matter (36 pp.)

Previous Issue: New Series, Vol. 280, No. 5368, May 29, 1998
Next Issue: New Series, Vol. 280, No. 5370, Jun. 12, 1998

Previous Issue: New Series, Vol. 280, No. 5369, Jun. 5, 1998
Next Issue: New Series, Vol. 280, No. 5371, Jun. 19, 1998

Front Matter (26 pp.)
NetWatch, p. 1663
Jocelyn Kaiser

Editorial: Making the Case for Federal Support of R&D, p. 1671
Franklin D. Raines

Letters

How Anthrax Kills, pp. 1671+1673-1674
Philip Hanna; Nicholas Duesbery; George Vande Woude; Stephen Leppla

Early Americans, pp. 1674-1675
Jean M. Auel

Conceiving a Black Hole, p. 1675
Laurent Hodges

Areas of the Brain: Movements and Memories, pp. 1676-1677
Daniel V. Meegan; Susan M. Courtney; Laurent Petit; Leslie G. Ungerleider; James V. Haxby

Corrections and Clarifications: Coral Disease, p. 1677
Corrections and Clarifications: Visual Input to the Efferent Control System of a Fly's 'Gyroscope', p. 1677
ScienceScope, p. 1681
Constance Holden

News and Comment

Global Change Fights Off a Chill, pp. 1682-1684
Andrew Lawler

Hot Year, but Cool Response in Congress, p. 1684
Gretchen Vogel; Andrew Lawler

Voters Reject Antigenetics Initiative, p. 1685
Robert Koenig

Editors Call for Misconduct Watchdog, pp. 1685-1686
Nigel Williams

Warm Words for Basic Research, p. 1686
Andrew Lawler

New Institutes Would Break Mold, p. 1687
Dennis Normile

Making Research Tools More Accessible, pp. 1687-1688
Eliot Marshall

NIH Examines Standards for Consent, p. 1688
Eliot Marshall

Research News

Weighing in on Neutrino Mass, pp. 1689-1690
Dennis Normile

The Fast Way to a Better Fuel Cell, pp. 1690-1691
Robert F. Service

Transistors and Diodes Link and Light Up, p. 1691
Robert F. Service

Sifting Through and Making Sense of Genome Sequences, pp. 1692-1693
Elizabeth Pennisi

Scientists Ponder Deep Slabs, Small Comets, Hidden Oceans, pp. 1694-1695
Richard A. Kerr

Random Samples, p. 1697
Constance Holden

Essays on Science and Society

Envisioning Science-a Personal Perspective, pp. 1698-1700
Felice Frankel

Science's Compass

Policy

A Molecular Biology Network for Asia and the Pacific Rim, p. 1708
Nancy Y. Ip; Gurinder Shahi

Books

Forty Years in the Conceptual Wilderness, pp. 1709-1710
The Antidepressant Era.
David Healy

Review author[s]: Merton Sandler

Locating Sustainability, p. 1710
Taking Complexity Seriously. Policy Analysis, Triangulation and Sustainable Development.
Emery Roe

Review author[s]: Bryan G. Norton

Research

The Biology of Being Frazzled, pp. 1711-1712
Amy F. T. Arnsten

Cytochrome c Oxidase: One Enzyme, Two Mechanisms?, pp. 1712-1713
Robert B. Gennis

Hominid Brain Evolution: Looks Can be Deceiving, p. 1714
Dean Falk

How to Have Your Cake and Eat it Too, p. 1715
John B. Pethica

Review

A Defect-Tolerant Computer Architecture: Opportunities for Nanotechnology, pp. 1716-1721
James R. Heath; Philip J. Kuekes; Gregory S. Snider; R. Stanley Williams

Research Article

Redox-Coupled Crystal Structural Changes in Bovine Heart Cytochrome c Oxidase, pp. 1723-1729
Shinya Yoshikawa; Kyoko Shinzawa-Itoh; Ryosuke Nakashima; Rieko Yaono; Eiki Yamashita; Noriko Inoue; Min Yao; Ming Jie Fei; Clare Peters Libeu; Tsunehiro Mizushima; Hiroshi Yamaguchi; Takashi Tomizaki; Tomitake Tsukihara

Reports

Endocranial Capacity in an Early Hominid Cranium from Sterkfontein, South Africa, pp. 1730-1731
Glenn C. Conroy; Gerhard W. Weber; Horst Seidler; Phillip V. Tobias; Alex Kane; Barry Brunsden

Single-Molecule Vibrational Spectroscopy and Microscopy, pp. 1732-1735
B. C. Stipe; M. A. Rezaei; W. Ho

Combinatorial Electrochemistry: A Highly Parallel, Optical Screening Method for Discovery of Better Electrocatalysts, pp. 1735-1737
Erik Reddington; Anthony Sapienza; Bogdan Gurau; Rameshkrishnan Viswanathan; S. Sarangapani; Eugene S. Smotkin; Thomas E. Mallouk

Compatibility of Rhenium in Garnet During Mantle Melting and Magma Genesis, pp. 1737-1741
Kevin Righter; Erik H. Hauri

Integrated Optoelectronic Devices Based on Conjugated Polymers, pp. 1741-1744
Henning Sirringhaus; Nir Tessler; Richard H. Friend

Carbon Nanotube Quantum Resistors, pp. 1744-1746
Stefan Frank; Philippe Poncharal; Z. L. Wang; Walt A. de Heer

Hormone-Dependent Coactivator Binding to a Hydrophobic Cleft on Nuclear Receptors, pp. 1747-1749
Weijun Feng; Ralff C. J. Ribeiro; Richard L. Wagner; Hoa Nguyen; James W. Apriletti; Robert J. Fletterick; John D. Baxter; Peter J. Kushner; Brian L. West

Mutation of BCL-6 Gene in Normal B Cells by the Process of Somatic Hypermutation of Ig Genes, pp. 1750-1752
Hong Ming Shen; Andrew Peters; Beverly Baron; Xiangdong Zhu; Ursula Storb

Mutation of a Gene Encoding a Protein with Extracellular Matrix Motifs in Usher Syndrome Type IIa, pp. 1753-1757
James D. Eudy; Michael D. Weston; SuFang Yao; Denise M. Hoover; Heidi L. Rehm; Manling Ma-Edmonds; Denise Yan; Iqbal Ahmad; Jason J. Cheng; Carmen Ayuso; Cor Cremers; Sandra Davenport; Claes Moller; Catherine B. Talmadge; Kirk W. Beisel; Marta Tamayo; Cynthia C. Morton; Anand Swaroop; William J. Kimberling; Janos Sumegi

Promotion of Met-tRNA ^Met _i Binding to Ribosomes by yIF2, a Bacterial IF2 Homolog in Yeast, pp. 1757-1760
Sang Ki Choi; Joon H. Lee; Wendy L. Zoll; William C. Merrick; Thomas E. Dever

The Ubiquitin-Related Protein RUB1 and Auxin Response in Arabidopsis, pp. 1760-1763
J. C. del Pozo; C. Timpte; S. Tan; J. Callis; M. Estelle

Close Contacts with the Endoplasmic Reticulum as Determinants of Mitochondrial Ca ²⁺ Responses, pp. 1763-1766
Rosario Rizzuto; Paolo Pinton; Walter Carrington; Frederic S. Fay; Kevin E. Fogarty; Lawrence M. Lifshitz; Richard A. Tuft; Tullio Pozzan

Back Matter (34 pp.)

Previous Issue: New Series, Vol. 280, No. 5369, Jun. 5, 1998
Next Issue: New Series, Vol. 280, No. 5371, Jun. 19, 1998

Previous Issue: New Series, Vol. 280, No. 5370, Jun. 12, 1998
Next Issue: New Series, Vol. 280, No. 5372, Jun. 26, 1998

Front Matter (34 pp.)
NetWatch, p. 1807
Jocelyn Kaiser

Editorial: Science and the Control of AIDS, p. 1815
Harold Varmus; Neal Nathanson

Letters

Access to Information on the Web, pp. 1815+1817
Lee Giles; Steve Lawrence; Bob Krovetz; G. N. Rassam

Investment in Tokamak Fusion, p. 1817
Alexander J. Glass

Cerebellum and Learning: A Complex Problem, pp. 1817-1819
Germund Hesslow; Christopher Yeo; Jeansok J. Kim; David J. Krupa; Richard F. Thompson

Progression to AIDS, pp. 1819-1820
Sharyne M. Donfield; Henry S. Lynn; Margaret W. Hilgartner; Michael W. Smith; Michael Dean; Mary Carrington; Cheryl Winkler; Stephen J. O'Brien

Correction, p. 1821
Mark M. Davis

Duplicate Publication, p. 1821
Stephen L. Mayo

ScienceScope, p. 1825
Constance Holden

News and Comment

U.S.-Style Universities for Germany?, pp. 1826-1827
Martin Enserink

Lawmakers Back R&D Boosts for 1999, pp. 1827-1828
Andrew Lawler

Imura Gets Job on Top-Level Council, pp. 1828-1829
Dennis Normile

Science Emerges from the 'Dark Age' of the Ceausescus, pp. 1829-1830
Robert Koenig

Review Boards: A System 'in Jeopardy'?, pp. 1830-1831
Eliot Marshall

Australia Takes Two-Step Approach on Genetic Studies, pp. 1831-1832
Elizabeth Finkel

Research News

Revealing HIV's T Cell Passkey, pp. 1833-1834
Michael Balter

Neutron Stars Spin Out Gravity Waves, p. 1835
Meher Antia

Giant Survey Wallpapers the Sky, p. 1835
James Glanz

Supernova and Gamma Burst Might Have Common Source, p. 1836
Govert Schilling

Parsing the Trilobites' Rise and Fall, p. 1837
Robert Irion

Females Pick Good Genes in Frogs, Flies, pp. 1837-1838
Elizabeth Pennisi

Embryo's Organizational Chart Redrawn, pp. 1838-1839
Gretchen Vogel

Heavy News on Solar Neutrinos, p. 1839
Dennis Normile

New Language Could Meld the Web Into a Seamless Database, pp. 1840-1841
Dana Mackenzie

Year of the Cat-in More Ways Than One, p. 1841
Ken Garber

Random Samples, p. 1843
Constance Holden

Essays on Science and Society

The Science of AIDS: A Tale of Two Worlds, pp. 1844-1845
Peter Piot

AIDS Research

[Introduction], p. 1855
Barbara R. Jasny; Daniel Clery

News

Europe: AIDS Research on a Budget, pp. 1856-1858
Michael Balter

Access to Patients is Key to Success of Dutch Quartet, p. 1859
Michael Balter

Modest Briton Stirs Up Storm With Views on Role of CTLs, pp. 1860-1861
Michael Balter

Duo Brings Hope of Immune Restoration, p. 1861
Michael Balter

A Cluster of Europe's AIDS Research Stars, p. 1862
Michael Balter

Global Program Struggles to Stem the Flood of New Cases, pp. 1863-1864
Michael Balter

Viewpoints

A National Tissue Bank to Track HIV Eradication and Immune Reconstitution, pp. 1865-1866
Winston Cavert; Ashley T. Haase

Toward HIV Eradication or Remission: The Tasks Ahead, pp. 1866-1867
David D. Ho

Limitations of a Molecular Clock Applied to Considerations of the Origin of HIV-1, pp. 1868-1871
Bette Korber; James Theiler; Steven Wolinsky

HIV Treatment Failure: Testing for HIV Resistance in Clinical Practice, pp. 1871-1873
Luc Perrin; Amalio Telenti

HIV/AIDS Prevention in Thailand: Success and Challenges, pp. 1873-1874
Wiput Phoolcharoen

Progress in the Development of an HIV-1 Vaccine, pp. 1875-1880
Norman L. Letvin

HIV-1 Regulatory/Accessory Genes: Keys to Unraveling Viral and Host Cell Biology, pp. 1880-1884
Michael Emerman; Michael H. Malim

The HIV-1 Envelope Glycoproteins: Fusogens, Antigens, and Immunogens, pp. 1884-1888
Richard Wyatt; Joseph Sodroski

Research Article

The NIMH Multisite HIV Prevention Trial: Reducing HIV Sexual Risk Behavior, pp. 1889-1894
The National Institute of Mental Health (NIMH) Multisite HIV Prevention Trial Group

Science's Compass

Policy

Logging and Tropical Forest Conservation, pp. 1899-1900
Ian A. Bowles; R. E. Rice; R. A. Mittermeier; G. A. B. da Fonseca

Books

Unexpected Effects, pp. 1901-1902
The Powerful Placebo. From Ancient Priest to Modern Physician.
Arthur K. Shapiro; Elaine Shapiro

Review author[s]: Esther M. Sternberg

Developmental Diversity, p. 1902
Embryology. Constructing the Organism.
Scott F. Gilbert; Anne M. Raunio

Review author[s]: Richard Emlet

Research

Black Carbon and the Carbon Cycle, pp. 1903-1904
Thomas A. J. Kuhlbusch

Hot Electrons in Magnetic Oxides, pp. 1904-1905
B. Keimer

Aligning Science with Politics and Policy in HIV Prevention, pp. 1905-1906
Karen Hein

How Calcium Enhances Plant Salt Tolerance, pp. 1906-1907
Emanuel Epstein

Reports

Black Carbon in Deep-Sea Sediments, pp. 1911-1913
C. A. Masiello; E. R. M. Druffel

Elasticity of Single-Crystal MgO to 8 Gigapascals and 1600 Kelvin, pp. 1913-1916
Ganglin Chen; Robert C. Liebermann; Donald J. Weidner

The Influence of Vegetation-Atmosphere-Ocean Interaction on Climate During the Mid-Holocene, pp. 1916-1919
Andrey Ganopolski; Claudia Kubatzki; Martin Claussen; Victor Brovkin; Vladimir Petoukhov

Planar Patterned Magnetic Media Obtained by Ion Irradiation, pp. 1919-1922
C. Chappert; H. Bernas; J. Ferré; V. Kottler; J.-P. Jamet; Y. Chen; E. Cambril; T. Devolder; F. Rousseaux; V. Mathet; H. Launois

Post-Cambrian Trilobite Diversity and Evolutionary Faunas, pp. 1922-1925
Jonathan M. Adrain; Richard A. Fortey; Stephen R. Westrop

Visualization of the Local Insulator-Metal Transition in Pr _0.7 Ca _0.3 MnO₃, pp. 1925-1928
Manfred Fiebig; Kenjiro Miyano; Yoshinori Tomioka; Yasuhide Tokura

Call Duration as an Indicator of Genetic Quality in Male Gray Tree Frogs, pp. 1928-1930
Allison M. Welch; Raymond D. Semlitsch; H. Carl Gerhardt

Neural Correlates of Perceptual Rivalry in the Human Brain, pp. 1930-1934
Erik D. Lumer; Karl J. Friston; Geraint Rees

Proton Transfer Pathways in Bacteriorhodopsin at 2.3 Angstrom Resolution, pp. 1934-1937
Hartmut Luecke; Hans-Thomas Richter; Janos K. Lanyi

Bloodstream- Versus Tick-Associated Variants of a Relapsing Fever Bacterium, pp. 1938-1940
Tom G. Schwan; B. Joseph Hinnebusch

Gating of CaMKII by cAMP-Regulated Protein Phosphatase Activity During LTP, pp. 1940-1943
Robert D. Blitzer; John H. Connor; George P. Brown; Tony Wong; Shirish Shenolikar; Ravi Iyengar; Emmanuel M. Landau

A Calcium Sensor Homolog Required for Plant Salt Tolerance, pp. 1943-1945
Jiping Liu; Jian-Kang Zhu

Stabilization of Interleukin-2 mRNA by the c-Jun NH₂-Terminal Kinase Pathway, pp. 1945-1949
Ching-Yi Chen; Fabienne Del Gatto-Konczak; Zhenguo Wu; Michael Karin

A Conserved HIV gp 120 Glycoprotein Structure Involved in Chemokine Receptor Binding, pp. 1949-1953
Carlo D. Rizzuto; Richard Wyatt; Nivia Hernández-Ramos; Ying Sun; Peter D. Kwong; Wayne A. Hendrickson; Joseph Sodroski

Tech.Sight

Seeing the Machinery of Live Cells, pp. 1954-1955
Roger Y. Tsien; Atsushi Miyawaki

PCR on a Roller Coaster, p. 1956
Richard Peters; Robert Sikorski

Homing Viruses, pp. 1956-1957
Robert Sikorski; Richard Peters

Demystifying Intranets, p. 1957
Robert Sikorski; Richard Peters

Back Matter (55 pp.)

Previous Issue: New Series, Vol. 280, No. 5370, Jun. 12, 1998
Next Issue: New Series, Vol. 280, No. 5372, Jun. 26, 1998

Previous Issue: New Series, Vol. 280, No. 5371, Jun. 19, 1998
Next Issue: New Series, Vol. 281, No. 5373, Jul. 3, 1998

Front Matter (41 pp.)
NetWatch, p. 2019
Jocelyn Kaiser

Editorial: Reaching Out for World Health, p. 2027
Gro Harlem Brundtland

Letters

Scientist-Diplomats, p. 2027
Peter A. Cohen

Spacelab's Worth, pp. 2027+2029
Simon Ostrach; Andrew Lawler

Global Temperature Patterns, pp. 2029-2030
Michael E. Mann; Raymond S. Bradley; Malcolm K. Hughes; Philip D. Jones

Renaming the "Henneman Size Principle", p. 2031
Joel A. Vilensky; Sid Gilman

Populations as "Species-in-Waiting"?, pp. 2031-2033
Kai M. A. Chan; Jennifer Hughes

Corrections and Clarifications, p. 2033
Corrections and Clarifications: New Role for Estrogen in Cancer?, p. 2033
ScienceScope, p. 2037
David Kestenbaum

News and Comment

Did Test Ban Watchdog Fail to Bark?, pp. 2038-2040
Eliot Marshall

Los Alamos Ally Gets Top DOE Post, p. 2040
Andrew Lawler

Rock Dates Thrown into Doubt, Researcher Under Fire, pp. 2041-2042
David Malakoff

ESA Commits to Hubble's Successor, p. 2042
Alexander Hellemans

Dexter Takes Over Wellcome Trust's Pot of Gold, pp. 2043-2044
Nigel Williams

New Fullerene Rounds Out the Family, p. 2044
Robert F. Service

Research News

Teaching the Brain to Take Drugs, pp. 2045-2047
Ingrid Wickelgren

Seeking the Sun's Deepest Notes, p. 2047
Alexander Hellemans

A Tangled Tale of E. coli Virulence, p. 2048
Kristin Weidenbach

El Niño Drives Spectacular Flower Show, pp. 2048-2049
Richard A. Lovett

Cosmic Web Captures Lost Matter, pp. 2049-2050
James Glanz

Possible New Weapon for Insect Control, p. 2050
Evelyn Strauss

Dinosaur Fossils, in Fine Feather, Show Link to Birds, p. 2051
Ann Gibbons

Random Samples, p. 2053
Constance Holden

Essays on Science and Society

Putting Science in the Hands of the Public, pp. 2054-2055
Goéry Delacôte

Science's Compass

Policy

The "Roll Back Malaria" Campaign, pp. 2067-2068
David N. Nabarro; Elizabeth M. Tayler

Books

Contingency and Convergence, pp. 2068-2070
The Crucible of Creation. The Burgess Shale and the Rise of Animals.
Simon Conway Morris

Review author[s]: Mike Foote

Research

Give and Ye Shall be Recognized, pp. 2070-2071
Claus Wedekind

New Insights on the Kuiper Belt, pp. 2071-2073
Alessandro Morbidelli

Life at the Freezing Point, pp. 2073-2074
Roland Psenner; Birgit Sattler

G Proteins and Small GTPases: Distant Relatives Keep in Touch, pp. 2074-2075
Alan Hall

Reports

Plasticity Induced by Shock Waves in Nonequilibrium Molecular-Dynamics Simulations, pp. 2085-2088
Brad Lee Holian; Peter S. Lomdahl

Design and Fabrication of Topologically Complex, Three-Dimensional Microstructures, pp. 2089-2091
Rebecca J. Jackman; Scott T. Brittain; Allan Adams; Mara G. Prentiss; George M. Whitesides

From Shifting Silt to Solid Stone: The Manufacture of Synthetic Basalt in Ancient Mesopotamia, pp. 2091-2093
E. C. Stone; D. H. Lindsley; V. Pigott; G. Harbottle; M. T. Ford

(Mg,Fe)SiO₃-Perovskite Stability Under Lower Mantle Conditions, pp. 2093-2095
G. Serghiou; A. Zerr; R. Boehler

Perennial Antarctic Lake Ice: An Oasis for Life in a Polar Desert, pp. 2095-2098
John C. Priscu; Christian H. Fritsen; Edward E. Adams; Stephen J. Giovannoni; Hans W. Paerl; Christopher P. McKay; Peter T. Doran; Douglas A. Gordon; Brian D. Lanoil; James L. Pinckney

Gold Nanoelectrodes of Varied Size: Transition to Molecule-Like Charging, pp. 2098-2101
Shaowei Chen; Roychelle S. Ingram; Michael J. Hostetler; Jeremy J. Pietron; Royce W. Murray; T. Gregory Schaaff; Joseph T. Khoury; Marcos M. Alvarez; Robert L. Whetten

Giant Electrostriction and Relaxor Ferroelectric Behavior in Electron-Irradiated Poly(vinylidene fluoride-trifluoroethylene) Copolymer, pp. 2101-2104
Q. M. Zhang; Vivek Bharti; X. Zhao

Neptune's Eccentricity and the Nature of the Kuiper Belt, pp. 2104-2106
William R. Ward; Joseph M. Hahn

Embryonic Folate Metabolism and Mouse Neural Tube Defects, pp. 2107-2109
Angeleen Fleming; Andrew J. Copp

p115 RhoGEF, a GTPase Activating Protein for Gα ₁₂ and Gα ₁₃, pp. 2109-2111
Tohru Kozasa; Xuejun Jiang; Matthew J. Hart; Pamela M. Sternweis; William D. Singer; Alfred G. Gilman; Gideon Bollag; Paul C. Sternweis

Direct Stimulation of the Guanine Nucleotide Exchange Activity of p115 RhoGEF by Gα ₁₃, pp. 2112-2114
Matthew J. Hart; Xuejun Jiang; Tohru Kozasa; William Roscoe; William D. Singer; Alfred G. Gilman; Paul C. Sternweis; Gideon Bollag

Type IV Pili, Transient Bacterial Aggregates, and Virulence of Enteropathogenic Escherichia coli, pp. 2114-2118
David Bieber; Sandra W. Ramer; Cheng-Yen Wu; William J. Murray; Toru Tobe; Rosemary Fernandez; Gary K. Schoolnik

Drosophila Synapse Formation: Regulation by Transmembrane Protein with Leu-Rich Repeats, CAPRICIOUS, pp. 2118-2121
Emiko Shishido; Masatoshi Takeichi; Akinao Nose

Abolition of Long-Term Stability of New Hippocampal Place Cell Maps by NMDA Receptor Blockade, pp. 2121-2126
Clifford Kentros; Eric Hargreaves; Robert D. Hawkins; Eric R. Kandel; Matthew Shapiro; Robert V. Muller

Edge Effects and the Extinction of Populations Inside Protected Areas, pp. 2126-2128
Rosie Woodroffe; Joshua R. Ginsberg

Insecticidal Toxins from the Bacterium Photorhabdus luminescens, pp. 2129-2132
David Bowen; Thomas A. Rocheleau; Michael Blackburn; Olga Andreev; Elena Golubeva; Rohit Bhartia; Richard H. ffrench-Constant

Technical Comments

Ambiguities in Direct Dating of Rock Surfaces Using Radiocarbon Measurements, pp. 2132-2139
W. Beck; D. J. Donahue; A. J. T. Jull; G. Burr; W. S. Broecker; G. Bonani; I. Hajdas; E. Malotki; Ronald I. Dorn

AAAS News and Notes, pp. 2143-2145
Lisa Crye

Back Matter (31 pp.)

Previous Issue: New Series, Vol. 280, No. 5371, Jun. 19, 1998
Next Issue: New Series, Vol. 281, No. 5373, Jul. 3, 1998

Previous Issue: New Series, Vol. 280, No. 5372, Jun. 26, 1998
Next Issue: New Series, Vol. 281, No. 5374, Jul. 10, 1998

Front Matter (20 pp.)
NetWatch, p. 7
Jocelyn Kaiser

News

News of the Week

U.S. R&D Budget Becomes Political Football, pp. 16-17
Eliot Marshall; Andrew Lawler

Signs of Past Collapse Beneath Antarctic Ice, pp. 17+19
Richard A. Kerr

Earth to SOHO, Come in Please, pp. 19-20
Alexander Hellemans

ScienceScope, pp. 19+21
Canada Proposes $175 Million Effort, p. 20
Wayne Kondro

Remodeled ESA Backs Applications Projects, pp. 20-21
Helen Gavaghan

Panel Says some UFO Reports Worthy of Study, p. 21
David Kestenbaum

NIH Panel Revives EMF-Cancer Link, pp. 21-22
Jocelyn Kaiser

No Consensus on Rules for AIDS Vaccine Trials, pp. 22-23
Jon Cohen

Fungus May Drive Frog Genocide, p. 23
Jocelyn Kaiser

Eight Millennia of Footwear Fashion, pp. 23+25
Heather Pringle

Successful Flies Make Love, Not War, p. 25
Gretchen Vogel

News Focus

Competition Heats Up on the Road to Fusion, pp. 26-29
Michael Baker; J. G; Andrew Lawler; James Glanz

Arms Control Enters the Biology Lab, pp. 29-30
Helen Gavaghan

New Gene Found for Inherited Macular Degeneration, p. 31
Elizabeth Pennisi

Tracking Down Mutations That Can Stop the Heart, pp. 32-34
Marcia Barinaga

Infections: A Cause of Artery-Clogging Plaques?, pp. 35+37
Trisha Gura

Random Samples, p. 39
Constance Holden

Essays on Science and Society

Beauty, Charm, and Strangeness: Science as Metaphor, pp. 40-41
John Banville

Science's Compass

Editorial

Elements of Our Design, p. 43
Floyd E. Bloom

Letters

No Surprises?, p. 45
Tim White; Dean Falk

Lung Ventilation and Gas Exchange in Theropod Dinosaurs, pp. 45-48
James W. Hicks; Colleen G. Farmer; Peter N. Nassar; Richard Hengst; John A. Ruben; Terry D. Jones; Nicholas R. Geist; W. Jaap Hillenius

Policy

The Scientific Investments of Nations, pp. 49-51
Robert M. May

Books and New Media

The Productivity Payoff of Computers, p. 52
The Computer Revolution. An Economic Perspective.
Daniel E. Sichel

Review author[s]: Yannis Bakos

Los Alamos Stories, p. 53
Secret Mesa: Inside Los Alamos National Laboratory.
Jo Ann Shroyer

Review author[s]: Hugh Gusterson

Order at the End, p. 54
Endnote 3.0.
Niles and Associates

Review author[s]: Brian Shmaefsky

Perspectives

Is the Rotation Real?, pp. 55-56
Annie Souriau

Under Control, pp. 56-57
Philippe Grangier

Another p53 Doppelgänger?, pp. 57-58
William G. Kaelin Jr.

Secret Life of Cytochrome bc₁, pp. 58-59
Janet L. Smith

Review

Going the Distance: A Current View of Enhancer Action, pp. 60-63
Elizabeth M. Blackwood; James T. Kadonaga

Research

Research Article

Complete Structure of the 11-Subunit Bovine Mitochondrial Cytochrome bc₁ Complex, pp. 64-71
So Iwata; Joong W. Lee; Kengo Okada; John Kyongwon Lee; Momi Iwata; Bjarne Rasmussen; Thomas A. Link; S. Ramaswamy; Bing K. Jap

Reports

7500 Years of Prehistoric Footwear from Arnold Research Cave, Missouri, pp. 72-75
Jenna T. Kuttruff; S. Gail DeHart; Michael J. O'Brien

Dissociative Recombination of HD⁺ in Selected Vibrational Quantum States, pp. 75-78
Z. Amitay; A. Baer; M. Dahan; L. Knoll; M. Lange; J. Levin; I. F. Schneider; D. Schwalm; A. Suzor-Weiner; Z. Vager; R. Wester; A. Wolf; D. Zajfman

An Inverted Hexagonal Phase of Cationic Liposome-DNA Complexes Related to DNA Release and Delivery, pp. 78-81
Ilya Koltover; Tim Salditt; Joachim O. Rädler; Cyrus R. Safinya

Pleistocene Collapse of the West Antarctic Ice Sheet, pp. 82-85
Reed P. Scherer; Ala Aldahan; Slawek Tulaczyk; Göran Possnert; Hermann Engelhardt; Barclay Kamb

Effects of Water on the α-β Transformation Kinetics in San Carlos Olivine, pp. 85-87
Tomoaki Kubo; Eiji Ohtani; Takumi Kato; Toru Shinmei; Kiyoshi Fujino

High-Temperature Silicate Volcanism on Jupiter's Moon Io, pp. 87-90
A. S. McEwen; L. Keszthelyi; J. R. Spencer; G. Schubert; D. L. Matson; R. Lopes-Gautier; K. P. Klaasen; T. V. Johnson; J. W. Head; P. Geissler; S. Fagents; A. G. Davies; M. H. Carr; H. H. Breneman; M. J. S. Belton

Mixer, a Homeobox Gene Required for Endoderm Development, pp. 91-96
Gilbert L. Henry; Douglas A. Melton

Visualization of Specific B and T Lymphocyte Interactions in the Lymph Node, pp. 96-99
Paul Garside; Elizabeth Ingulli; Rebecca R. Merica; Julia G. Johnson; Randolph J. Noelle; Marc K. Jenkins

C₁ Transfer Enzymes and Coenzymes Linking Methylotrophic Bacteria and Methanogenic Archaea, pp. 99-102
Ludmila Chistoserdova; Julia A. Vorholt; Rudolf K. Thauer; Mary E. Lidstrom

Reproductive Dominance of Pasture Trees in a Fragmented Tropical Forest Mosaic, pp. 103-105
Preston R. Aldrich; J. L. Hamrick

Interaction of Human Arp2/3 Complex and the Listeria monocytogenes ActA Protein in Actin Filament Nucleation, pp. 105-108
Matthew D. Welch; Jody Rosenblatt; Justin Skoble; Daniel A. Portnoy; Timothy J. Mitchison

Congenital Heart Disease Caused by Mutations in the Transcription Factor NKX2-5, pp. 108-111
Jean-Jacques Schott; D. Woodrow Benson; Craig T. Basson; William Pease; G. Michael Silberbach; Jeffrey P. Moak; Barry J. Maron; Christine E. Seidman; J. G. Seidman

Back Matter (21 pp.)

Previous Issue: New Series, Vol. 280, No. 5372, Jun. 26, 1998
Next Issue: New Series, Vol. 281, No. 5374, Jul. 10, 1998

Previous Issue: New Series, Vol. 281, No. 5373, Jul. 3, 1998
Next Issue: New Series, Vol. 281, No. 5375, Jul. 17, 1998

Front Matter (22 pp.)
NetWatch, p. 139
Jocelyn Kaiser

News

News of the Week

A Planned Boost for Genome Sequencing, but the Plan is in Flux, pp. 148-149
Elizabeth Pennisi

First Images Show Monkey Brains at Work, p. 149
Marcia Barinaga

Small Molecule Fills Hormone's Shoes, pp. 149+151
Marcia Barinaga

ScienceScope, pp. 151+153

News

News of the Week

NIH Urged to Involve the Public in Policy-Making, p. 152
Eliot Marshall

Hints of a Nearby Solar System?, pp. 152-153
Govert Schilling

Bacteria to Blame for Kidney Stones?, p. 153
Gretchen Vogel

First Glimpse of the Last Neutrino?, p. 155
Meher Antia

A Quieter Forecast for Southern California, p. 155
Richard A. Kerr

News Focus

Warming's Unpleasant Surprise: Shivering in the Greenhouse?, pp. 156-158
Richard A. Kerr

International AIDS Meeting Injects a Dose of Realism, pp. 159-160
Michael Balter; Jon Cohen

U.S. Tries Variations on High School Curriculum, pp. 161+163
Jeffrey Mervis

Major Reforms Proposed to Improve Science Payoffs, pp. 163-164
Michael Baker

Race for Stronger Magnets Turns into Marathon, pp. 164-165
Dennis Normile

Geological Analysis Damps Ancient Chinese Fires, pp. 165-166
Bernice Wuethrich

How Embryos Shape Up, pp. 166-167
Evelyn Strauss

Random Samples, p. 169
Constance Holden

Essays on Science and Society

Hooray, Hooray! It's Science! The Sixth-Grader's Perspective, pp. 170-171
Mera Dorner; Lucas Gustafson; Nick Nagel; Katie Ryan; Nicole Boyd; Maxwell Beavan; Kate Metz

Science's Compass

Editorial

On the Crest of a New Ocean Agenda, p. 173
James D. Watkins

Letters

The Indian Psyche, p. 175
G. Padmanaban

The Future of Bioengineering, pp. 175-176
David L. Slocum

Searching the Web, Continued, pp. 176-177
Molly Molloy; Steve Lawrence; C. Lee Giles

Policy Forum

Coherence in Science Education, pp. 178-179
Marjorie G. Bardeen; Leon M. Lederman

Books and New Media

History in Flames, pp. 180-181
Vestal Fire. An Environmental History, Told Through Fire, of Europe and Europe's Encounter with the World.
Stephen J. Pyne

Review author[s]: Johan Goudsblom

Perspectives

Dusty Disks and Planet Mania, pp. 182-183
Paul Kalas

In Balance, with a Little Help from the Plants, pp. 183-184
Pieter P. Tans; James W. C. White

Rad9 Comes of Age, pp. 185-186
Nancy C. Walworth

Monie a Mickle Maks a Muckle, p. 186
Richard Gallagher

Chemistry and Biology of the Oceans

[Introduction], p. 189
Julia Uppenbrink; Brooks Hanson; Richard Stone

News

Death by Suffocation in the Gulf of Mexico, pp. 190-192
David Malakoff

Ecology's Catch of the Day, pp. 192-193
Karen Schmidt

Instruments Cast Fresh Eyes on the Sea, pp. 194-196
Robert Irion

Stirring Up the Chesapeake's Cradle of Life, pp. 196-197
Jocelyn Kaiser

Viewpoint

Principles for Sustainable Governance of the Oceans, pp. 198-199
Robert Costanza; Francisco Andrade; Paula Antunes; Marjan van den Belt; Dee Boersma; Donald F. Boesch; Fernando Catarino; Susan Hanna; Karin Limburg; Bobbi Low; Michael Molitor; Joáo Gil Pereira; Steve Rayner; Rui Santos; James Wilson; Michael Young

Review

Biogeochemical Controls and Feedbacks on Ocean Primary Production, pp. 200-206
Paul G. Falkowski; Richard T. Barber; Victor Smetacek

Acquisition and Utilization of Transition Metal Ions by Marine Organisms, pp. 207-210
Alison Butler

Climate-Ocean Variability and Ecosystem Response in the Northeast Pacific, pp. 210-217
John A. McGowan; Daniel R. Cayan; LeRoy M. Dorman

Nutrient Biogeochemistry of the Coastal Zone, pp. 217-222
T. D. Jickells

The Quantum Event of Oceanic Crustal Accretion: Impacts of Diking at Mid-Ocean Ridges, pp. 222-230
J. R. Delaney; D. S. Kelley; M. D. Lilley; D. A. Butterfield; J. A. Baross; W. S. D. Wilcock; R. W. Embley; M. Summit

Research

Reports

Major Bacterial Contribution to Marine Dissolved Organic Nitrogen, pp. 231-234
Matthew D. McCarthy; John I. Hedges; Ronald Benner

The CO₂ Balance of Unproductive Aquatic Ecosystems, pp. 234-236
Carlos M. Duarte; Susana Agustí

Primary Production of the Biosphere: Integrating Terrestrial and Oceanic Components, pp. 237-240
Christopher B. Field; Michael J. Behrenfeld; James T. Randerson; Paul Falkowski

Abrupt Shift in Subsurface Temperatures in the Tropical Pacific Associated with Changes in El Niño, pp. 240-243
Thomas P. Guilderson; Daniel P. Schrag

Solidus of Earth's Deep Mantle, pp. 243-246
A. Zerr; A. Diegeler; R. Boehler

A Reduction-Pyrolysis-Catalysis Synthesis of Diamond, pp. 246-247
Yadong Li; Yitai Qian; Hongwei Liao; Yi Ding; Li Yang; Cunyi Xu; Fangqing Li; Guien Zhou

MR Imaging Contrast Enhancement Based on Intermolecular Zero Quantum Coherences, pp. 247-251
Warren S. Warren; Sangdoo Ahn; Marlene Mescher; Michael Garwood; Kamil Ugurbil; Wolfgang Richter; Rahim R. Rizi; Jeff Hopkins; John S. Leigh

Evidence for the Use of Fire at Zhoukoudian, China, pp. 251-253
Steve Weiner; Qinqi Xu; Paul Goldberg; Jinyi Liu; Ofer Bar-Yosef

Design of a 20-Amino Acid, Three-Stranded β-Sheet Protein, pp. 253-256
Tanja Kortemme; Marina Ramírez-Alvarado; Luis Serrano

A Small, Nonpeptidyl Mimic of Granulocyte-Colony-Stimulating Factor, pp. 257-259
Shin-Shay Tian; Peter Lamb; Andrew G. King; Stephen G. Miller; Linda Kessler; Juan I. Luengo; Laurie Averill; Randall K. Johnson; John G. Gleason; Louis M. Pelus; Susan B. Dillon; Jonathan Rosen

Infrared MALDI Mass Spectrometry of Large Nucleic Acids, pp. 260-262
Stefan Berkenkamp; Finn Kirpekar; Franz Hillenkamp

Structure of the Escherichia coli RNA Polymerase α Subunit Amino- Terminal Domain, pp. 262-266
Gongyi Zhang; Seth A. Darst

Cell Cycle Arrest by Vpr in HIV-1 Virions and Insensitivity to Antiretroviral Agents, pp. 266-269
Betty Poon; Kathie Grovit-Ferbas; Sheila A. Stewart; Irvin S. Y. Chen

Specific Covalent Labeling of Recombinant Protein Molecules Inside Live Cells, pp. 269-272
B. Albert Griffin; Stephen R. Adams; Roger Y. Tsien

Rad53 FHA Domain Associated with Phosphorylated Rad9 in the DNA Damage Checkpoint, pp. 272-274
Zhaoxia Sun; James Hsiao; David S. Fay; David F. Stern

Back Matter (22 pp.)

Previous Issue: New Series, Vol. 281, No. 5373, Jul. 3, 1998
Next Issue: New Series, Vol. 281, No. 5375, Jul. 17, 1998

Previous Issue: New Series, Vol. 281, No. 5374, Jul. 10, 1998
Next Issue: New Series, Vol. 281, No. 5376, Jul. 24, 1998

Front Matter (41 pp.)
NetWatch, p. 303
Jocelyn Kaiser

News

News of the Week

U.K. Government, Wellcome Trust Give $1.75 Billion Boost to R&D, pp. 314-315
Nigel Williams

Smuggled Chinese Fossils on Exhibit, pp. 315+317
Mutsumi Stone; Jennifer Couzin; Li Hui

ScienceScope, p. 317
Plant Biologists Score Two New Major Facilities, pp. 317-318
Jocelyn Kaiser

Epidemiologist Named CDC Director, p. 318
Eliot Marshall

Russian Academy to End AIP Journals Deal?, pp. 318-319
Andrey Allakhverdov

Relief from Finance Farce?, p. 319
Andrey Allakhverdov; Vladimir Pokrovsky

A Fruitful Scoop for Ancient DNA, pp. 319-320
Erik Stokstad

Glow Reveals Early Star Nurseries, p. 320
Andrew Watson

Hydrogen Coaxed into Quantum Condensate, p. 321
David Kestenbaum

Building a Better Bug Repellent, pp. 321+323
Luis Campos

Green Farming by the Incas?, p. 323
Kevin Krajick

News Focus

Genome Reveals Wiles and Weak Points of Syphilis, pp. 324-325
Elizabeth Pennisi

Scientists Step Onto the Political Stage, pp. 326-327
Robert Koenig

Turbulent Times Mean Trouble for Science, pp. 327+329
Jeffrey Mervis

Tracking the History of the Genetic Code, pp. 329-331
Gretchen Vogel

The First Codon and Its Descendants, p. 330
Elizabeth Pennisi

Plant Biology in the Genome Era, pp. 331-332
Christine Mlot

A Dark Matter Candidate Loses Its Luster, pp. 332-333
James Glanz

Random Samples, p. 335
Constance Holden

Essays on Science and Society

The Role of Science in Sustainable Development, pp. 336-337
Angela Merkel

Science's Compass

Editorial

Budget-The Big Picture, p. 345
Henry J. Aaron

Letters

The Alpha Magnetic Spectrometer, p. 347
Robert P. Redwine

Kenyan Wildlife Conservation, pp. 347-348
Agi Kiss

Embryology and Evolution, pp. 348-349
Michael J. Behe; Klaus Sander; Roland Bender

Tick Population Trends and Forest Type, pp. 349-351
Howard S. Ginsberg; Kerwin E. Hyland; Renjie Hu; Thomas J. Daniels; Richard C. Falco; Richard S. Ostfeld; Clive G. Jones; Michele P. Richard; Eric M. Schauber; Jerry O. Wolff

Corrections and Clarifications: NIH Urged to Involve the Public in Policy- Making, p. 351

Policy

Elimination of Syphilis in the United States, pp. 353-354
Michael E. St. Louis; Judith N. Wasserheit

Books and New Media

Into Jurassic Air, pp. 355-356
Taking Wing: Archaeopteryx and the Evolution of Bird Flight.
Pat Shipman

Review author[s]: Sharon Swartz

Mapping Natural Communities and Ecosystems, p. 356
A Classification of North American Biotic Communities.
David E. Brown; Frank Reichenbacher; Susan E. Franson

Ecoregions. The Ecosystem Geography of the Oceans and Continents.
Robert G. Bailey

Review author[s]: Sherman Suter

Perspectives

Switching with Hot Spins, pp. 357+359
Jo De Boeck

Giant Planets to Brown Dwarfs: What is in Between?, pp. 359-360
Filipe D. Santos

A Tale of Two Transmitters, pp. 360-361
Roger A. Nicoll; Robert C. Malenka

Tech.Sight

A Sequencing Method Based on Real-Time Pyrophosphate, pp. 363+365
Mostafa Ronaghi; Mathias Uhlén; Pål Nyrén

TechSightings, pp. 366-369
Richard Peters; Robert Sikorski

Research

Research Article

Complete Genome Sequence of Treponema pallidum, the Syphilis Spirochete, pp. 375-388
Claire M. Fraser; Steven J. Norris; George M. Weinstock; Owen White; Granger G. Sutton; Robert Dodson; Michelle Gwinn; Erin K. Hickey; Rebecca Clayton; Karen A. Ketchum; Erica Sodergren; John M. Hardham; Michael P. McLeod; Steven Salzberg; Jeremy Peterson; Hanif Khalak; Delwood Richardson; Jerrilyn K. Howell; Monjula Chidambaram; Teresa Utterback; Lisa McDonald; Patricia Artiach; Cheryl Bowman; Matthew D. Cotton; Claire Fujii; Stacey Garland; Bonnie Hatch; Kurt Horst; Kevin Roberts; Mina Sandusky; Janice Weidman; Hamilton O. Smith; J. Craig Venter

Reports

Reversible Hydrogels from Self-Assembling Artificial Proteins, pp. 389-392
Wendy A. Petka; James L. Harden; Kevin P. McGrath; Denis Wirtz; David A. Tirrell

Atmospheric Residence Time of CH₃Br Estimated from the Junge Spatial Variability Relation, pp. 392-396
Jonah J. Colman; Donald R. Blake; F. Sherwood Rowland

Water as a Dense Icelike Component in Silicate Glasses, pp. 396-398
P. Richet; A. Polian

Evidence for Large Earthquakes in Metropolitan Los Angeles, pp. 398-402
Charles M. Rubin; Scott C. Lindvall; Thomas K. Rockwell

Molecular Coproscopy: Dung and Diet of the Extinct Ground Sloth Nothrotheriops shastensis, pp. 402-406
Hendrik N. Poinar; Michael Hofreiter; W. Geoffrey Spaulding; Paul S. Martin; B. Artur Stankiewicz; Helen Bland; Richard P. Evershed; Göran Possnert; Svante Pääbo

Room Temperature-Operating Spin-Valve Transistors Formed by Vacuum Bonding, pp. 407-409
D. J. Monsma; R. Vlutters; J. C. Lodder

Boundary Formation in Drosophila Wing: Notch Activity Attenuated by the POU Protein Nubbin, pp. 409-413
Carl J. Neumann; Stephen M. Cohen

Uncoupling of Nonreceptor Tyrosine Kinases from PLC-γ1 in an SLP-76- Deficient T Cell, pp. 413-416
Deborah Yablonski; Michelle R. Kuhne; Theresa Kadlecek; Arthur Weiss

Requirement for the Leukocyte-Specific Adapter Protein SLP-76 for Normal T Cell Development, pp. 416-419
James L. Clements; Baoli Yang; Susan E. Ross-Barta; Steve L. Eliason; Ronald F. Hrstka; Roger A. Williamson; Gary A. Koretzky

Corelease of Two Fast Neurotransmitters at a Central Synapse, pp. 419-424
Peter Jonas; Josef Bischofberger; Jürgen Sandkühler

Spatial Organization of Transcription Elongation Complex in Escherichia coli, pp. 424-428
Evgeny Nudler; Ivan Gusarov; Ekaterina Avetissova; Maxim Kozlov; Alex Goldfarb

Combinatorial Chemistry in Insects: A Library of Defensive Macrocyclic Polyamines, pp. 428-431
Frank C. Schröder; Jay J. Farmer; Athula B. Attygalle; Scott R. Smedley; Thomas Eisner; Jerrold Meinwald

Back Matter (45 pp.)

Previous Issue: New Series, Vol. 281, No. 5374, Jul. 10, 1998
Next Issue: New Series, Vol. 281, No. 5376, Jul. 24, 1998

Previous Issue: New Series, Vol. 281, No. 5375, Jul. 17, 1998
Next Issue: New Series, Vol. 281, No. 5377, Jul. 31, 1998

Front Matter (23 pp.)
Netwatch, p. 483
Jocelyn Kaiser

News

News of the Week

Indian Scientists Shaken by Bomb Test Aftershocks, pp. 494-495
Pallava Bagla

Cloned Mice Provide Company for Dolly, pp. 495+497
Elizabeth Pennisi

ScienceScope, p. 497
Negative Review Galls Space Crystallographers, pp. 497-498
Jennifer Couzin

Allègre Sets Tough Targets for Research, p. 498
Michael Balter

Chain of Errors Hurled Probe into Spin, p. 499
James Glanz

West Antarctica's Weak Underbelly Giving Way?, pp. 499-500
Richard A. Kerr

How the Brain Sees in Three Dimensions, pp. 500-501
Marcia Barinaga

First Ticks of a Super Atom Clock, p. 501
David Kestenbaum

Earth's Unbounded Beetlemania Explained, pp. 501+503
Virginia Morell

How Plants Pick Their Mates, p. 503
Evelyn Strauss

News Focus

Coming to Grips with the World's Greenhouse Gases, pp. 504-506
Karen Schmidt

New Network Aims to Take the World's CO₂ Pulse, pp. 506-507
Jocelyn Kaiser

New Gene Tied to Common Form of Alzheimer's, pp. 507+509
Jean Marx

Random Samples, p. 511
Constance Holden

Essays on Science and Society

Popular Culture and the Threat to Rational Inquiry, pp. 512-513
Douglas R. Hofstadter

Science's Compass

Editorial

French Strategy for Science Education, p. 515
Claude Allègre

Letters

Patenting Genes, p. 517
Allan H. Fried; Marilou E. Watson; Michael A. Heller; Rebecca S. Eisenberg

The End of Public Higher Education, pp. 517-518
Brewster C. Denny

Elevated Atmospheric CO₂ and Soil Biota, p. 518
Shuijin Hu; Mary K. Firestone; F. Stuart Chapin III

Geomagnetic Reversals, pp. 518-519
A. K. Baksi; John Peck

Policy

Toward Safe and Effective Medical Abortion, pp. 520-521
Wendy R. Ewart; Beverly Winikoff

Books and New Media

Still Stimulating After All These Years, pp. 522-523
The Expression of the Emotions in Man and Animals.
Charles Darwin

Review author[s]: Steven Pinker

Focusing Cell Biology, pp. 523-524
Picture Control. The Electron Microscope and the Transformation of Biology in America, 1940-1960.
Nicolas Rasmussen

Review author[s]: Peter Satir

Perspectives

The Challenge of Gamma Ray Burst Observations, pp. 525-526
Peter J. T. Leonard

Kondo Effect in Quantum Dots, pp. 526-527
Takeshi Inoshita

Translating Affinity into Response, pp. 528-529
Bernard Malissen

Softening Support for Macintoshes, p. 529
Kevin Ahern

Research

Reports

Rotation of a Single Molecule Within a Supramolecular Bearing, pp. 531-533
J. K. Gimzewski; C. Joachim; R. R. Schlittler; V. Langlais; H. Tang; I. Johannsen

Exploiting Chemical Libraries, Structure, and Genomics in the Search for Kinase Inhibitors, pp. 533-538
Nathanael S. Gray; Lisa Wodicka; Andy-Mark W. H. Thunnissen; Thea C. Norman; Soojin Kwon; F. Hernan Espinoza; David O. Morgan; Georjana Barnes; Sophie LeClerc; Laurent Meijer; Sung-Hou Kim; David J. Lockhart; Peter G. Schultz

Synthesis of Macroporous Minerals with Highly Ordered Three-Dimensional Arrays of Spheroidal Voids, pp. 538-540
Brian T. Holland; Christopher F. Blanford; Andreas Stein

A Tunable Kondo Effect in Quantum Dots, pp. 540-544
Sara M. Cronenwett; Tjerk H. Oosterkamp; Leo P. Kouwenhoven

Mass-Independent Oxygen Isotope Fractionation in Atmospheric CO as a Result of the Reaction CO + OH, pp. 544-546
T. Röckmann; C. A. M. Brenninkmeijer; G. Saueressig; P. Bergamaschi; J. N. Crowley; H. Fischer; P. J. Crutzen

A Correlation between Ultra-Low Basal Velocities in the Mantle and Hot Spots, pp. 546-549
Q. Williams; J. Revenaugh; E. Garnero

Fast Recession of a West Antarctic Glacier, pp. 549-551
E. J. Rignot

Distance Modulation of Neural Activity in the Visual Cortex, pp. 552-555
Allan C. Dobbins; Richard M. Jeo; József Fiser; John M. Allman

"Inordinate Fondness" Explained: Why are There so Many Beetles?, pp. 555-559
Brian D. Farrell

Activity-Dependent Cortical Target Selection by Thalamic Axons, pp. 559-562
Susan M. Catalano; Carla J. Shatz

A Viral Mechanism for Inhibition of the Cellular Phosphatase Calcineurin, pp. 562-565
James E. Miskin; Charles C. Abrams; Lynnette C. Goatley; Linda K. Dixon

Delivery of Epitopes by the Salmonella Type III Secretion System for Vaccine Development, pp. 565-568
Holger Rüssmann; Homayoun Shams; Fernando Poblete; Yixin Fu; Jorge E. Galán; Ruben O. Donis

An Unusual Mechanism for Ligand Antagonism, pp. 568-572
Chikako Torigoe; John K. Inman; Henry Metzger

Fidelity of T Cell Activation Through Multistep T Cell Receptor ζ Phosphorylation, pp. 572-575
Ellen Neumeister Kersh; Andrey S. Shaw; Paul M. Allen

Inactivation of a Serotonin-Gated Ion Channel by a Polypeptide Toxin from Marine Snails, pp. 575-578
Laura J. England; Julita Imperial; Richard Jacobsen; A. Grey Craig; Joseph Gulyas; Mateen Akhtar; Jean Rivier; David Julius; Baldomero M. Olivera

Back Matter (30 pp.)

Previous Issue: New Series, Vol. 281, No. 5375, Jul. 17, 1998
Next Issue: New Series, Vol. 281, No. 5377, Jul. 31, 1998

Previous Issue: New Series, Vol. 281, No. 5376, Jul. 24, 1998
Next Issue: New Series, Vol. 281, No. 5378, Aug. 7, 1998

Front Matter (21 pp.)
NetWatch, p. 615
Jocelyn Kaiser

News

News of the Week

New Study Points to Eurasian Ape as Great Ape Ancestor, pp. 622-623
Ann Gibbons

Clinton's R&D Chiefs Waiting on Sidelines, p. 623
Andrew Lawler

U.S., Ukraine Launch New Chernobyl Lab, pp. 623+625
Richard Stone

Outside Insider Named to Head EPA Research, pp. 625-626
Jocelyn Kaiser

ScienceScope, pp. 625+627
Eliot Marshall; Susan Biggin; Pallava Bagla; Richard Stone

Vanishing Pools Taking Species with Them, p. 626
Kathryn S. Brown

Did Twisty Starlight Set Stage for Life?, pp. 626-627
Robert Irion

A Sulfurous Start for Protein Synthesis?, pp. 627+629
Gretchen Vogel

Molecular Imaging Beats Limits of Light, p. 629
Rob van den Berg

News Focus

A Shadow Falls on Hepatitis B Vaccination Effort, pp. 630-631
Eliot Marshall

Possible Cause Found for Lyme Arthritis, pp. 631-632
Steven Dickman

Field Emitters Finding Home in Electronics, pp. 632-633
Dennis Normile

The Sahara is Not Marching Southward, pp. 633-634
Richard A. Kerr

Sphere Does Elegant Gymnastics in New Video, pp. 634-635
Dana Mackenzie

Physicist-Turned-Politician Seeks Middle Ground, pp. 635-636
Andrew Lawler

Gravity Teases Details from Ancient Cosmic Birthplaces, p. 637
James Glanz

Random Samples, p. 639
Constance Holden

Essays on Science and Society

The Challenge of Faust, pp. 640-641
Hans Christoph Binswanger

Science's Compass

Editorial

Training for Today's Marketplace, p. 645
Elizabeth Marincola; Frank Solomon

Letters

Scientific Literacy, p. 647
Richard L. Hinman

That Corner Office, p. 647
Frank Selker

The Plight of Postdocs, p. 647
Trevor M. Penning

Strategies for Carbon Reduction, pp. 647-649
Ronald J. Sutherland; Joseph Romm; Mark Levine; Marilyn Brown; Eric Petersen

Policy Forum

ART into Science: Regulation of Fertility Techniques, pp. 651-652
ISLAT Working Group

Books and New Media

A Piece of Your Mind, pp. 653-654
How the Mind Works.
Steven Pinker

Review author[s]: Melvin Konner

Boundaries in Blood, p. 654
Drawing Blood. Technology and Disease Identity in Twentieth-Century America.
Keith Wailoo

Review author[s]: John T. Truman

Perspectives

Two Views of the Deep Mantle, pp. 655-656
Jeroen Tromp; Adam M. Dziewonski

Buried Spins in Slow Motion, pp. 656-657
J. M. Kikkawa; D. D. Awschalom

Genetic Medicine-When Will it Come to the Drugstore?, pp. 657-658
Pernilla Wittung-Stafshede

All You Need is RNA, pp. 658-659
Paul Schimmel; Rebecca Alexander

Review

An Integrated Model of the Transcription Complex in Elongation, Termination, and Editing, pp. 660-665
Peter H. von Hippel

Research

Research Article

Reconstitution of Peptide Bond Formation with Escherichia coli 23S Ribosomal RNA Domains, pp. 666-669
Itaru Nitta; Yoshie Kamada; Hiroe Noda; Takuya Ueda; Kimitsuna Watanabe

Reports

Peptides by Activation of Amino Acids with CO on (Ni,Fe)S Surfaces: Implications for the Origin of Life, pp. 670-672
Claudia Huber; Günter Wächtershäuser

Circular Polarization in Star-Formation Regions: Implications for Biomolecular Homochirality, pp. 672-674
Jeremy Bailey; Antonio Chrysostomou; J. H. Hough; T. M. Gledhill; Alan McCall; Stuart Clark; François Ménard; Motohide Tamura

Elastic Moduli of Wadsleyite (b-Mg₂SiO₄) to 7 Gigapascals and 873 Kelvin, pp. 675-677
Baosheng Li; Robert C. Liebermann; Donald J. Weidner

Ultrasonic Shear Wave Velocities of MgSiO₃ Perovskite at 8 GPa and 800 K and Lower Mantle Composition, pp. 677-679
Yegor D. Sinelnikov; Ganglin Chen; Daniel R. Neuville; Michael T. Vaughan; Robert C. Liebermann

Multi-Atom Resonant Photoemission: A Method for Determining Near-Neighbor Atomic Identities and Bonding, pp. 679-683
A. Kay; E. Arenholz; S. Mun; F. J. García de Abajo; C. S. Fadley; R. Denecke; Z. Hussain; M. A. Van Hove

Visualization of Three-Dimensional Chaos, pp. 683-686
G. O. Fountain; D. V. Khakhar; J. M. Ottino

Ultraslow Electron Spin Dynamics in GaAs Quantum Wells Probed by Optically Pumped NMR, pp. 686-690
N. N. Kuzma; P. Khandelwal; S. E. Barrett; L. N. Pfeiffer; K. W. West

Near Extinction of a Large, Widely Distributed Fish, pp. 690-692
Jill M. Casey; Ransom A. Myers

Regulation of a Transcription Factor Network Required for Differentiation and Metabolism, pp. 692-695
Stephen A. Duncan; M. Angeles Navas; Daniel Dufort; Janet Rossant; Markus Stoffel

Impact of a Catastrophic Hurricane on Island Populations, pp. 695-697
David A. Spiller; Jonathan B. Losos; Thomas W. Schoener

Nucleation of COPII Vesicular Coat Complex by Endoplasmic Reticulum to Golgi Vesicle SNAREs, pp. 698-700
Sebastian Springer; Randy Schekman

Functional Reconstitution of Ypt7p GTPase and a Purified Vacuole SNARE Complex, pp. 700-702
Ken Sato; William Wickner

Identification of LFA-1 as a Candidate Autoantigen in Treatment-Resistant Lyme Arthritis, pp. 703-706
Dawn M. Gross; Thomas Forsthuber; Magdalena Tary-Lehmann; Carey Etling; Kouichi Ito; Zoltan A. Nagy; Jodie A. Field; Allen C. Steere; Brigitte T. Huber

Pioneer Axon Guidance by UNC-129, a C. elegans TGF-β, pp. 706-709
Antonio Colavita; Srikant Krishna; Hong Zheng; Richard W. Padgett; Joseph G. Culotti

Concerted Evolution in an Egg Receptor for a Rapidly Evolving Abalone Sperm Protein, pp. 710-712
Willie J. Swanson; Victor D. Vacquier

AAAS News and Notes, pp. 714-715
Tiffany Ayers

Back Matter (25 pp.)

Previous Issue: New Series, Vol. 281, No. 5376, Jul. 24, 1998
Next Issue: New Series, Vol. 281, No. 5378, Aug. 7, 1998

Previous Issue: New Series, Vol. 281, No. 5377, Jul. 31, 1998
Next Issue: New Series, Vol. 281, No. 5379, Aug. 14, 1998

Front Matter (23 pp.)
Netwatch, p. 747
Jocelyn Kaiser

News

News of the Week

Practical Tests for an 'Untestable' Theory of Everything?, pp. 758-759
David Kestenbaum

Physicist Named Japan's Education Minister, pp. 759+761
Dennis Normile

Fusion Facility Faces Fall Deadline, pp. 761-762
Andrew Lawler

ScienceScope, pp. 761+763
Computer Experts Urge New Federal Initiative, p. 762
Jennifer Couzin

Gravity Measurements Ride the Atom Wave, pp. 762-763
Robert F. Service

A Two-Piece Protein Assembles Itself, pp. 763-764
Gretchen Vogel

Accelerator Gets Set to Explore Cosmic Bias, pp. 764-765
Andrew Watson

Engineers Dream of Practical Star Flight, pp. 765+767
James Glanz

Paving the Way for British Xenotransplants, p. 767
Nigel Williams

USGS Nominee Breaks Ground, p. 767
Jocelyn Kaiser

News Focus

Agricultural Biotech Faces Backlash in Europe, pp. 768-771
Nigel Williams

China Hopes to Move FAST on Largest Telescope, pp. 771+773
Li Hui

Fight Erupts Over Rights to Profits from Holdings, pp. 773-774
Richard Stone

New Views of the Origins of Mammals, pp. 774-775
Dennis Normile

Random Samples, p. 777
Constance Holden

Essays on Science and Society

Closing the Knowledge Gap between Scientist and Nonscientist, pp. 778-779
Takashi Tachibana

Science's Compass

Editorial

Korean Science and Technology, p. 781
Chang-Hee Kang

Letters

The New Look, p. 783
Nicholas A. Halasz; Pat Mail; Susan Rabitan; Janet Rubin; Len Stephan; Bret Cooper; Dominic Eisinger

Making the Case for Science, p. 783
Mary Woolley

Dangerous Mixture, pp. 783-784
John C. Angus; Yadong Li

The Advanced Tokamak, p. 784
Richard D. Hazeltine; Gerald A. Navratil; William M. Nevins; Miklos Porkolab; Ned R. Sauthoff; Thomas C. Simonen; Weston M. Stacey

Indian Science, pp. 784-785
T. Balakrishna Reddy; G. Padmanaban

Arsenic-Laced Water in Chile, p. 785
Mary Lou Biggs; Reina Haque; Lee Moore; Allan Smith; Catterina Ferreccio; Claudia Hopenhayn-Rich

Household Antibiotic Storage, p. 785
Xavier Bosch; Rosamund J. Williams

Policy Forum

Database Protection and Access to Information, pp. 786-787
William Gardner; Joseph Rosenbaum

Books and New Media

Beyond the Null Hypothesis, p. 788
The Ecological Detective. Confronting Models with Data.
Ray Hilborn; Marc Mangel

Review author[s]: Thomas E. Miller; Gretchen LeBuhn

Neural Nets for Novices, p. 789
Neuroshell Easy: Predictor Classifier Run-Time.
Ward Systems Group

Review author[s]: John Wass

Perspectives

Coordinated Feet and the Dance of Ryanodine Receptors, pp. 790-791
Donald M. Bers; Michael Fill

A Complex Field, pp. 791-792
Rob van der Voo

Beyond Factorization and Search, pp. 792-794
Lov K. Grover

Choline, a Vital Amine, pp. 794-795
Jan Krzysztof Blusztajn

Research

Reports

The Magnetic Stability of Spin-Dependent Tunneling Devices, pp. 797-799
S. Gider; B.-U. Runge; A. C. Marley; S. S. P. Parkin

Evidence of Soft-Mode Quantum Phase Transitions in Electron Double Layers, pp. 799-802
Vittorio Pellegrini; Aron Pinczuk; Brian S. Dennis; Annette S. Plaut; Loren N. Pfeiffer; Ken W. West

Preparation of Photonic Crystals Made of Air Spheres in Titania, pp. 802-804
Judith E. G. J. Wijnhoven; Willem L. Vos

Diffusion Kinetics of Samarium and Neodymium in Garnet, and a Method for Determining Cooling Rates of Rocks, pp. 805-807
J. Ganguly; M. Tirone; R. L. Hervig

Decoupled Temporal Patterns of Evolution and Ecology in Two Post-Paleozoic Clades, pp. 807-809
Frank K. McKinney; Scott Lidgard; J. John Sepkoski Jr.; Paul D. Taylor

In situ Observations of a High-Pressure Phase of H₂O Ice, pp. 809-812
I-Ming Chou; Jennifer G. Blank; Alexander F. Goncharov; Ho-kwang Mao; Russell J. Hemley

Evidence Against a Significant Younger Dryas Cooling Event in New Zealand, pp. 812-814
Christiane Singer; James Shulmeister; Bill McLea

Callosal Window between Prefrontal Cortices: Cognitive Interaction to Retrieve Long-Term Memory, pp. 814-818
Isao Hasegawa; Tetsuya Fukushima; Takeshi Ihara; Yasushi Miyashita

Coupled Gating between Individual Skeletal Muscle Ca ²⁺ Release Channels (Ryanodine Receptors), pp. 818-821
Steven O. Marx; Karol Ondrias; Andrew R. Marks

Role of Phosphorylation in Regulation of the Assembly of Endocytic Coat Complexes, pp. 821-824
Vladimir I. Slepnev; Gian-Carlo Ochoa; Margaret H. Butler; Detlev Grabs; Pietro de Camilli

How Temperature Changes Reset a Circadian Oscillator, pp. 825-829
Yi Liu; Martha Merrow; Jennifer J. Loros; Jay C. Dunlap

RNA-Mediated Trans-Activation of Transcription from a Viral RNA, pp. 829-832
Tim L. Sit; Andrew A. Vaewhongs; Steven A. Lommel

Role of IQGAP1, a Target of the Small GTPases Cdc42 and Rac1, in Regulation of E-Cadherin-Mediated Cell-Cell Adhesion, pp. 832-835
Shinya Kuroda; Masaki Fukata; Masato Nakagawa; Katsuhiko Fujii; Tomoko Nakamura; Tadashi Ookubo; Ichiro Izawa; Takahiro Nagase; Nobuo Nomura; Hideki Tani; Ikuo Shoji; Yoshiharu Matsuura; Shin Yonehara; Kozo Kaibuchi

Positive Selection Through a Motif in the αβ T Cell Receptor, pp. 835-838
B. Thomas Bäckström; Urs Müller; Barbara Hausmann; Ed Palmer

DARPP-32: Regulator of the Efficacy of Dopaminergic Neurotransmission, pp. 838-842
A. A. Fienberg; N. Hiroi; P. G. Mermelstein; W.-J. Song; G. L. Snyder; A. Nishi; A. Cheramy; J. P. O'Callaghan; D. B. Miller; D. G. Cole; R. Corbett; C. N. Haile; D. C. Cooper; S. P. Onn; A. A. Grace; C. C. Ouimet; F. J. White; S. E. Hyman; D. J. Surmeier; J.-A. Girault; E. J. Nestler; P. Greengard

Back Matter (30 pp.)

Previous Issue: New Series, Vol. 281, No. 5377, Jul. 31, 1998
Next Issue: New Series, Vol. 281, No. 5379, Aug. 14, 1998

Previous Issue: New Series, Vol. 281, No. 5378, Aug. 7, 1998
Next Issue: New Series, Vol. 281, No. 5380, Aug. 21, 1998

Front Matter (34 pp.)
Netwatch, p. 879
Jocelyn Kaiser

News

News of the Week

Physicians Wary of Scheme to Pool Icelanders' Genetic Data, pp. 890-891
Martin Enserink

Hopes Rise After SOHO Calls Home, p. 891
James Glanz

Ultraenergetic Particles Slip Past Cosmic Cutoff, pp. 891+893
Dennis Normile

ScienceScope, pp. 893+895
Andrew Lawler; David Malakoff; Jocelyn Kaiser

IBM Puts Fast Chips on a New Footing, pp. 893-894
Robert F. Service

Asteroid Searchers Streak Ahead, pp. 894-895
Robert Irion

Tobacco Consultants Find Letters Lucrative, pp. 895+897
Jocelyn Kaiser

Albanians Vie for Control of Site, p. 897
Richard Stone

News Focus

The (Political) Science of Salt, pp. 898-901+903-907
Gary Taubes

Random Samples, p. 909
Robert F. Service

Essays on Science and Society

Living on the Edge, pp. 910-911
Helen Anderson

Science's Compass

Editorial

Scientific Literacy, p. 917
Jane Maienschein

Letters

UFOs and the Scientific Method, p. 919
Stuart Appelle

Henneman's Size Principle: The Right Name, p. 919
Andrew J. Fuglevand; Marc D. Binder

Division on the Internet?, pp. 919+921-923
Joachim Krueger; Joseph L. Graves Jr.; Philip L. Bereano; Adam Clayton Powell III; Al Globus; Hal J. Daniel III; Donna L. Hoffman; Thomas P. Novak

Corrections and Clarifications: Dangerous Mixture, p. 923
Corrections and Clarifications: Infl̈ections: A Cause of Artery-Clogging Plaques?, p. 923
Corrections and Clarifications: How Calcium Enhances Plant Salt Tolerance, p. 923
Corrections and Clarifications: Memory and Awareness, p. 923
Corrections and Clarifications: Skeletal Muscle Regeneration by Bone Marrow-Derived Myogenic Progenitors, p. 923

Science's Compass

Policy

Genomics and the World's Economy, pp. 925-926
Juan Enríquez

Books and New Media

Finding Purpose in Life, p. 927
Nature's Purposes. Analyses of Function and Design in Biology.
Colin Allen; Marc Bekoff; George Lauder

Review author[s]: R. McN. Alexander

Perspectives

Choosing a Place to Begin, pp. 929-930
Joel A. Huberman

Global Climate Data and Models: A Reconciliation, pp. 930-932
James E. Hansen; Makiko Sato; Reto Ruedy; Andrew Lacis; Jay Glascoe

Protostars and Planets, pp. 932-933
Sara S. Russell; Alan P. Boss

Diet and Blood Pressure-the Paradigm Shift, pp. 933-934
David A. McCarron

Control and Use of Defects in Materials

[Introduction], p. 939
Phil Szuromi; Daniel Clery

News

Superstrong Nanotubes Show They are Smart, Too, pp. 940-942
Robert F. Service

Cracks: More Than Just a Clean Break, pp. 943-944
Alexander Hellemans

Review

Defects in Semiconductors: Some Fatal, Some Vital, pp. 945-950
Hans J. Queisser; Eugene E. Haller

Making Nonmagnetic Semiconductors Ferromagnetic, pp. 951-956
H. Ohno

The Roles of Structural Imperfections in InGaN-Based Blue Light-Emitting Diodes and Laser Diodes, pp. 956-961
Shuji Nakamura

Effects of Random Perturbations in Plastic Optical Fibers, pp. 962-967
A. F. Garito; J. Wang; R. Gao

Research

Reports

Imperfect Oriented Attachment: Dislocation Generation in Defect-Free Nanocrystals, pp. 969-971
R. Lee Penn; Jillian F. Banfield

Tetravalent Uranium in Calcite, pp. 971-973
N. C. Sturchio; M. R. Antonio; L. Soderholm; S. R. Sutton; J. C. Brannon

Coaxial Nanocable: Silicon Carbide and Silicon Oxide Sheathed with Boron Nitride and Carbon, pp. 973-975
Y. Zhang; K. Suenaga; C. Colliex; S. Iijima

Evidence Against Hydrogen-Based Microbial Ecosystems in Basalt Aquifers, pp. 976-977
Robert T. Anderson; Francis H. Chapelle; Derek R. Lovley

Alteration of Oceanic Volcanic Glass: Textural Evidence of Microbial Activity, pp. 978-980
Martin R. Fisk; Stephen J. Giovannoni; Ingunn H. Thorseth

A 3000-Year Climatic Record from Biogenic Silica Oxygen Isotopes in an Equatorial High-Altitude Lake, pp. 980-982
M. Rietti-Shati; A. Shemesh; W. Karlen

Magnetic Field Effect on Picosecond Electron Transfer, pp. 982-984
P. Gilch; F. Pöllinger-Dammer; C. Musewald; M. E. Michel-Beyerle; U. E. Steiner

Cholinergic Switching Within Neocortical Inhibitory Networks, pp. 985-988
Zixiu Xiang; John R. Huguenard; David A. Prince

Neural Crest Specification Regulated by the Helix-Loop-Helix Repressor Id2, pp. 988-991
Brad J. Martinsen; Marianne Bronner-Fraser

Crystal Structure of Hemolin: A Horseshoe Shape with Implications for Homophilic Adhesion, pp. 991-995
Xiao-Dong Su; Louis N. Gastinel; Daniel E. Vaughn; Ingrid Faye; Pak Poon; Pamela J. Bjorkman

Dual Modes of Aging in Mediterranean Fruit Fly Females, pp. 996-998
James R. Carey; Pablo Liedo; Hans-Georg Müller; Jane-Ling Wang; James W. Vaupel

IEX-1L, an Apoptosis Inhibitor Involved in NF-κB-Mediated Cell Survival, pp. 998-1001
Mei X. Wu; Zhaohui Ao; K. V. S. Prasad; Ruilian Wu; Stuart F. Schlossman

Feedback Inhibition of Macrophage Tumor Necrosis Factor-α Production by Tristetraprolin, pp. 1001-1005
Ester Carballo; Wi S. Lai; Perry J. Blackshear

Genetic Dissection of a Mammalian Replicator in the Human β-Globin Locus, pp. 1005-1009
Mirit I. Aladjem; Luo Wei Rodewald; John L. Kolman; Geoffrey M. Wahl

BRCA1 Required for Transcription-Coupled Repair of Oxidative DNA Damage, pp. 1009-1012
Lori C. Gowen; Anna V. Avrutskaya; Anne M. Latour; Beverly H. Koller; Steven A. Leadon

Back Matter (88 pp.)

Previous Issue: New Series, Vol. 281, No. 5378, Aug. 7, 1998
Next Issue: New Series, Vol. 281, No. 5380, Aug. 21, 1998

Science, New Series, Vol. 281, No. 5380, Aug. 21, 1998

Previous Issue: New Series, Vol. 281, No. 5379, Aug. 14, 1998
Next Issue: New Series, Vol. 281, No. 5381, Aug. 28, 1998

Front Matter (22 pp.)

Netwatch, p. 1107

Jocelyn Kaiser

News

News of the Week

Geneticists Debate Eugenics and China's Infant Health Law, pp. 1118-1119

Dennis Normile

Doubled Genes May Explain Fish Diversity, pp. 1119+1121

Gretchen Vogel

A Second Private Genome Project, p. 1121

Eliot Marshall

ScienceScope, pp. 1121+1123

DNA Chips Survey an Entire Genome, p. 1122

Robert F. Service

How Embryos May Avoid Immune Attack, pp. 1122-1124

Trisha Gura

Neptune's Hasty Moon Poses Celestial Puzzle, p. 1124

Govert Schilling

Institute Copes with Genetic Hot Potato, pp. 1124-1125

Martin Enserink

Report Urges U.S. to Take the Long View, p. 1125

David Malakoff

London, Cambridge Lead Europe in Output, p. 1127

Daniel Clery

News Focus

The Next Oil Crisis Looms Large-and Perhaps Close, pp. 1128-1131

Richard A. Kerr

How the Genome Readies Itself for Evolution, pp. 1131+1133-1134

Elizabeth Pennisi

Under Pressure, Deuterium Gets into Quite a State, p. 1135

David Kestenbaum

Random Samples, p. 1137

Constance Holden

Essays on Science and Society

Opportunity Knocks!, pp. 1138-1139

Melvyn Bragg

Science's Compass

Editorial

U.K. Science Funding Increase, p. 1141

Tony Blair

Letters

Apple Corps, p. 1143

Randy M. Wadkins; Kevin Ahern

Journal Proliferation, p. 1143

Peter T. Shepherd

R_x for WHO, pp. 1143-1144

Rodney W. Nichols

Oceans and Climate Shifts, p. 1144

Hisashi Nakamura; Toshio Yamagata

Microelectromechanics, p. 1145

John C. Angus; Uziel Landau; George M. Whitesides

Federal Research Priorities, pp. 1145-1146

N. Richard Werthamer; Matthew Diehl

A Vision of the Pore, p. 1146

Tilly Bakker-Grunwald

Corrections and Clarifications: Toward Safe and Effective Medical Abortion, p. 1146

Corrections and Clarifications: Kenyan Wildlife Conservation, p. 1146

Corrections and Clarifications: Monie a Mickle Maks a Muckle, p. 1146

Corrections and Clarifications: Ecology's Catch of the Day, p. 1146

Corrections and Clarifications: Visualization of the Local Insulator-Metal Transition in Pr _0.7 Ca _0.3 MnO₃, p. 1146

Science's Compass

Policy Forum

State Policy and Pasture Degradation in Inner Asia, pp. 1147-1148

David Sneath

Books and New Media

Lack of Attention from Loss of Time, pp. 1149-1150

ADHD and the Nature of Self Control.

Russell A. Barkley

Review author[s]: Philip W. Gold

Bowfins and the Revenge of Comparative Biology, p. 1150

A Comprehensive Phylogenetic Study of Amiid Fishes (Amiidae) Based in Comparative Skeletal Anatomy. An Empirical Search for Interconnected Patterns of Natural History.

Lance Grande; William E. Bemis

Review author[s]: Philippe Janvier

Perspectives

Memories are Made of This, pp. 1151-1152

Michael D. Rugg

Just Add Water Vapor, pp. 1152-1153

David Rind

Electroweak Reconciliation, pp. 1153-1155

Michael E. Peskin

Electronic Confinement in Organic Metals, pp. 1155-1156

Claude Bourbonnais; Denis Jérome

Review

Biotic Transitions in Global Marine Diversity, pp. 1157-1160

Arnold I. Miller

Tech.Sight

Sustained Delivery of Proteins for Novel Therapeutic Products, pp. 1161-1162

Raymond T. Bartus; Mark A. Tracy; Dwaine F. Emerich; Stephen E. Zale

Tissue Cork Borer, p. 1163

Richard Peters; Robert Sikorski

A Frankenstein Experiment, pp. 1163-1164

Robert Sikorski; Richard Peters

XML is Hatching, p. 1164

Robert Sikorski; Richard Peters

Research

Reports

C, N, and Noble Gas Isotopes in Grain Size Separates of Presolar Diamonds from Efremovka, pp. 1165-1168

A. B. Verchovsky; A. V. Fisenko; L. F. Semjonova; I. P. Wright; M. R. Lee; C. T. Pillinger

Biogeochemical Evidence for Dinoflagellate Ancestors in the Early Cambrian, pp. 1168-1170

J. Michael Moldowan; Nina M. Talyzina

Moho Offset Across the Northern Margin of the Tibetan Plateau, pp. 1170-1172

Lupei Zhu; Donald V. Helmberger

Cambrian Burgess Shale Animals Replicated in Clay Minerals, pp. 1173-1175

Patrick J. Orr; Derek E. G. Briggs; Stuart L. Kearns

Variation of Interplate Fault Zone Properties with Depth in the Japan Subduction Zone, pp. 1175-1178

Susan L. Bilek; Thorne Lay

Measurements of the Equation of State of Deuterium at the Fluid Insulator- Metal Transition, pp. 1178-1181

G. W. Collins; L. B. da Silva; P. Celliers; D. M. Gold; M. E. Foord; R. J. Wallace; A. Ng; S. V. Weber; K. S. Budil; R. Cauble

Dimensionality-Driven Insulator-to-Metal Transition in the Bechgaard Salts, pp. 1181-1184

V. Vescoli; L. Degiorgi; W. Henderson; G. Grüner; K. P. Starkey; L. K. Montgomery

Making Memories: Brain Activity that Predicts How Well Visual Experience Will be Remembered, pp. 1185-1187

James B. Brewer; Zuo Zhao; John E. Desmond; Gary H. Glover; John D. E. Gabrieli

Building Memories: Remembering and Forgetting of Verbal Experiences as Predicted by Brain Activity, pp. 1188-1191

Anthony D. Wagner; Daniel L. Schacter; Michael Rotte; Wilma Koutstaal; Anat Maril; Anders M. Dale; Bruce R. Rosen; Randy L. Buckner

Prevention of Allogeneic Fetal Rejection by Tryptophan Catabolism, pp. 1191-1193

David H. Munn; Min Zhou; John T. Attwood; Igor Bondarev; Simon J. Conway; Brendan Marshall; Corrie Brown; Andrew L. Mellor

Direct Allelic Variation Scanning of the Yeast Genome, pp. 1194-1197

Elizabeth A. Winzeler; Dan R. Richards; Andrew R. Conway; Alan L. Goldstein; Sue Kalman; Michael J. McCullough; John H. McCusker; David A. Stevens; Lisa Wodicka; David J. Lockhart; Ronald W. Davis

Prototype of a Heme Chaperone Essential for Cytochrome c Maturation, pp. 1197-1200

Henk Schulz; Hauke Hennecke; Linda Thöny-Meyer

Determinants of Kinesin Motor Polarity, pp. 1200-1202

Sharyn A. Endow; Kimberly W. Waligora

Characterization of an Ammonium Transport Protein from the Peribacteroid Membrane of Soybean Nodules, pp. 1202-1206

Brent N. Kaiser; Patrick M. Finnegan; Stephen D. Tyerman; Lynne F. Whitehead; Fraser J. Bergersen; David A. Day; Michael K. Udvardi

Back Matter (34 pp.)

Previous Issue: New Series, Vol. 281, No. 5379, Aug. 14, 1998
Next Issue: New Series, Vol. 281, No. 5381, Aug. 28, 1998

Previous Issue: New Series, Vol. 281, No. 5380, Aug. 21, 1998
Next Issue: New Series, Vol. 281, No. 5382, Sep. 4, 1998

Front Matter (29 pp.)
Netwatch, p. 1247
Jennifer Couzin

News

News of the Week

Medical School Caught Up in Pennsylvania Hospital Debacle, pp. 1258-1259
Constance Holden

Did an Ancient Deep Freeze Nearly Doom Life?, pp. 1259+1261
Richard A. Kerr

NIH, DuPont Declare Truce in Mouse War, pp. 1261-1262
Eliot Marshall

ScienceScope, pp. 1261+1263
David Malakoff; Pallava Bagla; Wayne Kondro

Small Businesses Get Extra Boost from NSF, p. 1262
Jeffrey Mervis

Los Alamos Magnet Leads the Field, pp. 1262-1264
Robert F. Service

A New Route to Treating Schizophrenia?, pp. 1264-1265
Ingrid Wickelgren

Top Honors Go to Math with a Physics Flavor, pp. 1265+1267
Allyn Jackson

Packing Challenge Mastered at Last, p. 1267
Barry Cipra

News Focus

Wanted: A Better Way to Boost Numbers of Minority Ph.D.s, pp. 1268-1270
Jeffrey Mervis

NIH Concocts a Booster Shot for HIV Vaccines, pp. 1270-1271+1273
Jon Cohen

Botanical Gardens Cope with Bioprospecting Loophole, p. 1273
Alan Dove

Tracking Vanishing Mammals and Elusive Nitrogen, pp. 1274-1275
Jocelyn Kaiser; Kathryn S. Brown

Random Samples, p. 1277
Constance Holden

Essays on Science and Society

The Black Ribbon, pp. 1278-1279
Margaret J. Geller

Science's Compass

Editorial

Cell Death in Us and Others, p. 1283
Pierre Golstein

Letters

Retro-Laser, p. 1285
Ann Schaeffer

Neural Net Wizard, p. 1285
Review author[s]: Steven A. Ward

Beetle Juice, p. 1285
Frank R. Denton III; Jerrold Meinwald; Thomas Eisner; Frank Schröoder

Melting, Maybe, pp. 1285-1286
C. J. van der Veen

Learning from Others, p. 1286
Frank X. Sutman

A "Humouse" Project, pp. 1286-1287
Francis Galibert

DRD2 Gene and Alcoholism, pp. 1287-1288
Ernest P. Noble

Testing for Alzheimer's, pp. 1288-1289
Jon F. Merz; Mildred K. Cho; Debra D. G. B. Leonard

Haeckel's Embryos, Continued, p. 1289
Michael K. Richardson

Corrections and Clarifications: First Images Show Monkey Brains at Work, p. 1289
Corrections and Clarifications: New Clues to Alcoholism Risk, p. 1289

Science's Compass

Policy Forum

Food Production, Population Growth, and the Environment, pp. 1291-1292
Gretchen Daily; Partha Dasgupta; Bert Bolin; Pierre Crosson; Jacques du Guerny; Paul Ehrlich; Carl Folke; Ann Mari Jansson; Bengt-Owe Jansson; Nils Kautsky; Ann Kinzig; Simon Levin; Karl-Göran Mäler; Per Pinstrup-Andersen; Domenico Siniscalco; Brian Walker

Books and New Media

A Broad Look at Future Worlds, p. 1293
Which World? Scenarios for the 21st Century.
Allen Hammond

Review author[s]: Carl Folke

Atomic Philosophies, pp. 1293-1294
The Atom in the History of Human Thought.
Bernard Pullman; Axel Reisinger

Review author[s]: Diana Barkan

An Uneasy Marriage, p. 1294
Origin 5.0.
Microcal Software Inc.

Review author[s]: Bruce McCallum

Perspectives

Tropical Forests-Log 'em or Leave 'em?, pp. 1295-1296
Robin L. Chazdon

Superconductivity in a Grain of Salt, pp. 1296-1297
Russell J. Hemley

Faster is Better, pp. 1297-1298
Kenneth L. Verosub

Death by Crowd Control, pp. 1298-1299
Michael Hengartner

Apoptosis

[Introduction], p. 1301
Linda J. Miller; Jean Marx

News

Stroke-Damaged Neurons May Commit Cellular Suicide, pp. 1302-1303
Marcia Barinaga

Is Apoptosis Key in Alzheimer's Disease?, pp. 1303-1304
Marcia Barinaga

Reviews

Death Receptors: Signaling and Modulation, pp. 1305-1308
Avi Ashkenazi; Vishva M. Dixit

Mitochondria and Apoptosis, pp. 1309-1312
Douglas R. Green; John C. Reed

Caspases: Enemies Within, pp. 1312-1316
Nancy A. Thornberry; Yuri Lazebnik

A Matter of Life and Cell Death, pp. 1317-1322
Gerard Evan; Trevor Littlewood

The Bcl-2 Protein Family: Arbiters of Cell Survival, pp. 1322-1326
Jerry M. Adams; Suzanne Cory

Research

Research Article

Ocean Climate Change: Comparison of Acoustic Tomography, Satellite Altimetry, and Modeling, pp. 1327-1332
ATOC Consortium

Reports

Metallic Csl at Pressures of Up to 220 Gigapascals, pp. 1333-1335
M. I. Eremets; K. Shimizu; T. C. Kobayashi; K. Amaya

Response of Flexible Polymers to a Sudden Elongational Flow, pp. 1335-1340
Douglas E. Smith; Steven Chu

Three-Dimensional Deformation Measured in an Alaskan Glacier, pp. 1340-1342
Joel T. Harper; Neil F. Humphrey; W. Tad Pfeffer

A Neoproterozoic Snowball Earth, pp. 1342-1346
Paul F. Hoffman; Alan J. Kaufman; Galen P. Halverson; Daniel P. Schrag

Photofragment Helicity Caused by Matter-Wave Interference from Multiple Dissociative States, pp. 1346-1349
T. Peter Rakitzis; S. Alex Kandel; Andrew J. Alexander; Zee Hwan Kim; Richard N. Zare

Reversal of Phencyclidine Effects by a Group II Metabotropic Glutamate Receptor Agonist in Rats, pp. 1349-1352
Bita Moghaddam; Barbara W. Adams

Independent and Epigenetic Regulation of the Interleukin-4 Alleles in CD4⁺ T Cells, pp. 1352-1354
Mark Bix; Richard M. Locksley

Essential Role of CED-4 Oligomerization in CED-3 Activation and Apoptosis, pp. 1355-1357
Xiaolu Yang; Howard Y. Chang; David Baltimore

Structure and Asn-Pro-Phe Binding Pocket of the Eps15 Homology Domain, pp. 1357-1360
Tonny de Beer; Royston E. Carter; Katherine E. Lobel-Rice; Alexander Sorkin; Michael Overduin

Direct Phosphorylation of IκB by IKKα and IKKβ: Discrimination Between Free and NF-κB-Bound Substrate, pp. 1360-1363
Ebrahim Zandi; Yi Chen; Michael Karin

Optimizing Gaze Control in Three Dimensions, pp. 1363-1366
Douglas Tweed; Thomas Haslwanter; Michael Fetter

Tree Species Diversity in Commercially Logged Bornean Rainforest, pp. 1366-1368
Charles H. Cannon; David R. Peart; Mark Leighton

AAAS News and Notes, pp. 1372-1373
Tiffany Ayers

Back Matter (31 pp.)

Previous Issue: New Series, Vol. 281, No. 5380, Aug. 21, 1998
Next Issue: New Series, Vol. 281, No. 5382, Sep. 4, 1998

Previous Issue: New Series, Vol. 281, No. 5381, Aug. 28, 1998
Next Issue: New Series, Vol. 281, No. 5383, Sep. 11, 1998

Front Matter (32 pp.)
Netwatch, p. 1411
Jocelyn Kaiser

News

News of the Week

Britain Hunts Down CJD Epidemic in Removed Appendixes, pp. 1422-1423
Nigel Williams

Lunar Prospector Probes Moon's Core Mysteries, pp. 1423+1425
Robert Irion

New Hiv Strain Could Pose Health Threat, pp. 1425-1426
Michael Balter

ScienceScope, pp. 1425+1427
Study Finds 10% of Tree Species Under Threat, p. 1426
Nigel Williams

Theory Debate Gets Literary, and Ugly, p. 1427
Peter Rodgers

Proposed Scope Takes Mirror Size to the Max, p. 1428
Robert Irion

Galaxy's Oldest Stars Shed Light on Big Bang, pp. 1428-1429
Alexander Hellemans

New Timepiece has a Familiar Ring, pp. 1429+1431
Marcia Barinaga

Breathalyzer Device Sniffs for Disease, p. 1431
Robert F. Service

News Focus

Which of Our Genes Make Us Human?, pp. 1432-1434
Ann Gibbons

Vocal Critic Gets Chance to Put His Ideas into Practice, pp. 1435-1436
Dennis Normile

Legislators Get Creative with New Crop of Earmarks, pp. 1436-1438
David Malakoff

Big Bucks for Big Sky Country, p. 1437
Andrew Lawler

How a Growth Control Path Takes a Wrong Turn to Cancer, pp. 1438-1439+1441
Elizabeth Pennisi

Random Samples, p. 1443
Constance Holden

Essays on Science and Society

Fossils and the Social Future of Science, pp. 1444-1445
Geerat J. Vermeij

Science's Compass

Editorial

The Rightness of Copyright, p. 1451
Floyd E. Bloom

Letters

Logging On in the Rain Forest, pp. 1453-1457
Claude Gascon; Rita Mesquita; Niro Higuchi; Bruce J. Cabarle; Gary S. Hartshorn; Ian A. Bowles; Richard E. Rice; Russell A. Mittermeier; Gustavo A. B. da Fonseca

Errors in Genome Reviews, p. 1457
Nikos C. Kyrpides; Christos A. Ouzounis

Policy Forum

Who Should Own Scientific Papers?, pp. 1459-1460
Steven Bachrach; R. Stephen Berry; Martin Blume; Thomas von Foerster; Alexander Fowler; Paul Ginsparg; Stephen Heller; Neil Kestner; Andrew Odlyzko; Ann Okerson; Ron Wigington; Anne Moffat

Books and New Media

Libraries in the Digital Future, pp. 1461-1462
Books, Bricks, and Bytes. Libraries in the Twenty-First Century.
Stephen R. Graubard; Paul LeClerc

Review author[s]: Michael A. Keller

The World Between Crust and Core, pp. 1462-1463
The Earth's Mantle. Composition, Structure, and Evolution.
Ian Jackson

Review author[s]: David J. Stevenson

Virtual Valet, pp. 1463-1464
Gene Construction Kit 2.
Texto Inc.

Review author[s]: Theo Dreher; Daiki Matsuda

Perspectives

Driving the Growth Cone, pp. 1465-1466
Pico Caroni

Duplicating a Tangled Genome, pp. 1466-1467
Peter Cook

Glacial Puzzles, pp. 1467-1468
M. E. Raymo

Laser-Generated Jets and Megagauss Magnetic Fields, p. 1469
John Stamper

Research

Lunar Prospector Reports

Lunar Prospector: Overview, pp. 1475-1476
Alan B. Binder

Improved Gravity Field of the Moon from Lunar Prospector, pp. 1476-1480
A. S. Konopliv; A. B. Binder; L. L. Hood; A. B. Kucinskas; W. L. Sjogren; J. G. Williams

Lunar Surface Magnetic Fields and Their Interaction with the Solar Wind: Results from Lunar Prospector, pp. 1480-1484
R. P. Lin; D. L. Mitchell; D. W. Curtis; K. A. Anderson; C. W. Carlson; J. McFadden; M. H. Acuña; L. L. Hood; A. Binder

Global Elemental Maps of the Moon: The Lunar Prospector Gamma-Ray Spectrometer, pp. 1484-1489
D. J. Lawrence; W. C. Feldman; B. L. Barraclough; A. B. Binder; R. C. Elphic; S. Maurice; D. R. Thomsen

Major Compositional Units of the Moon: Lunar Prospector Thermal and Fast Neutrons, pp. 1489-1493
W. C. Feldman; B. L. Barraclough; S. Maurice; R. C. Elphic; D. J. Lawrence; D. R. Thomsen; A. B. Binder

Lunar Fe and Ti Abundances: Comparison of Lunar Prospector and Clementine Data, pp. 1493-1496
R. C. Elphic; D. J. Lawrence; W. C. Feldman; B. L. Barraclough; S. Maurice; A. B. Binder; P. G. Lucey

Fluxes of Fast and Epithermal Neutrons from Lunar Prospector: Evidence for Water Ice at the Lunar Poles, pp. 1496-1500
W. C. Feldman; S. Maurice; A. B. Binder; B. L. Barraclough; R. C. Elphic; D. J. Lawrence

Reports

Low-Temperature Synthesis of Zintl Compounds with a Single-Source Molecular Precursor, pp. 1500-1501
Michael A. Beswick; Nick Choi; Christopher N. Harmer; Alexander D. Hopkins; Mary McPartlin; Dominic S. Wright

Segregation of Transcription and Replication Sites into Higher Order Domains, pp. 1502-1505
Xiangyun Wei; Jagath Samarabandu; Rakendu S. Devdhar; Alan J. Siegel; Raj Acharya; Ronald Berezney

CBP: A Signal-Regulated Transcriptional Coactivator Controlled by Nuclear Calcium and CaM Kinase IV, pp. 1505-1509
Sangeeta Chawla; Giles E. Hardingham; David R. Quinn; Hilmar Bading

Identification of c-MYC as a Target of the APC Pathway, pp. 1509-1512
Tong-Chuan He; Andrew B. Sparks; Carlo Rago; Heiko Hermeking; Leigh Zawel; Luis T. da Costa; Patrice J. Morin; Bert Vogelstein; Kenneth W. Kinzler

Extrapolating Species Abundance Across Spatial Scales, pp. 1513-1515
William E. Kunin

Conversion of Neuronal Growth Cone Responses from Repulsion to Attraction by Cyclic Nucleotides, pp. 1515-1518
Hong-jun Song; Guo-li Ming; Zhigang He; Maxime Lehmann; Lisa McKerracher; Marc Tessier-Lavigne; Mu-ming Poo

Expression of a Gene Cluster kaiABC as a Circadian Feedback Process in Cyanobacteria, pp. 1519-1523
Masahiro Ishiura; Shinsuke Kutsuna; Setsuyuki Aoki; Hideo Iwasaki; Carol R. Andersson; Akio Tanabe; Susan S. Golden; Carl H. Johnson; Takao Kondo

Back Matter (37 pp.)

Previous Issue: New Series, Vol. 281, No. 5381, Aug. 28, 1998
Next Issue: New Series, Vol. 281, No. 5383, Sep. 11, 1998

Previous Issue: New Series, Vol. 281, No. 5382, Sep. 4, 1998
Next Issue: New Series, Vol. 281, No. 5384, Sep. 18, 1998

Front Matter (40 pp.)
Netwatch, p. 1567
Jocelyn Kaiser

News

News of the Week

Should Engineer Witnesses Meet Same Standards as Scientists?, p. 1578
Jocelyn Kaiser

Cattle Diet Linked to Bacterial Growth, pp. 1578-1579
Jennifer Couzin

Senate Committee Votes Boost for NIH, pp. 1579+1581
Eliot Marshall

RNA-Splicing Machinery Revealed, pp. 1581-1582
Dan Ferber

ScienceScope, p. 1581
Leptin Sparks Blood Vessel Growth, p. 1582
Marcia Barinaga

NSF Draws up Plans for $70 Million Plane, pp. 1583-1584
Jennifer Couzin

Report Paints Grim Outlook for Young Ph.D.s, p. 1584
Constance Holden

Transfer of Protein Data Bank Sparks Concern, pp. 1584-1585
Eliot Marshall

So Far, So Good for SOHO, pp. 1585+1587
Alexander Hellemans

Five Researchers Die in Plane Crash, p. 1587
Michael Balter

Bad Economy is Good News for R&D, p. 1587
Dennis Normile

News Focus

The Cerebellum: The Brain's Engine of Agility, pp. 1588-1590
Ingrid Wickelgren

Multiplying Knowledge of Cell Division, Plant Growth, pp. 1591+1593
Dennis Normile

Early Start for Lumpy Universe, p. 1593
Govert Schilling

Neutrinos Throw Their Weight Around, pp. 1594-1595
David Kestenbaum

Random Samples, p. 1597
Constance Holden

Essays on Science and Society

Women, Science, and Society, pp. 1599-1600
Sandra Harding

Science's Compass

Editorial

Airborne Particulate Matter, p. 1609
Philip H. Abelson

Letters

Quiescence in Nuclear Transfer, p. 1611
Ian Wilmut; Keith H. S. Campbell; James M. Robl; D. Joseph Jerry; Steven Stice; Jose Cibelli

The Future of Long Life, pp. 1611-1615
Leonid A. Gavrilov; Natalia S. Gavrilova; S. Jay Olshansky; Bruce A. Carnes; Christine Cassel; Joseph J. Strout; John R. Wilmoth

Corrections and Clarifications: Beetle Juice, p. 1615
Corrections and Clarifications: London, Cambridge Lead Europe in Output, p. 1615
Corrections and Clarifications: Primal Portraits, p. 1615
Corrections and Clarifications: Green Strategy for Water Flea, p. 1615
Corrections and Clarifications: Elephantine Gift Stirs Museum Debate, p. 1615
Corrections and Clarifications: Antagonism of Central Melanocortin Receptors In vitro and In vivo by Agouti-Related Protein, p. 1615

Policy Forum

The Paradox of Lead Poisoning Prevention, pp. 1617-1618
Bruce P. Lanphear

Books and New Media

Are We Selfish, Are We Nice, or Are We Nice because We Are Selfish?, pp. 1619+1621
Unto Others. The Evolution and Psychology of Unselfish Behavior.
Elliott Sober; David Sloan Wilson

Review author[s]: Leonard Nunney

Perspectives

Tales Told in Lead, pp. 1622-1623
Jerome O. Nriagu

Oceanic Effects on Earth's Rotation Rate, pp. 1623-1624
Clark R. Wilson

Reward for Persistence in Substance P Research, pp. 1624-1625
Claes Wahlestedt

Routing MAP Kinase Cascades, pp. 1625-1626
Elaine A. Elion

Research

Research Articles

History of Atmospheric Lead Deposition Since 12,370 ¹⁴ C yr BP from a Peat Bog, Jura Mountains, Switzerland, pp. 1635-1640
W. Shotyk; D. Weiss; P. G. Appleby; A. K. Cheburkin; R. Frei; M. Gloor; J. D. Kramers; S. Reese; W. O. Van Der Knaap

Distinct Mechanism for Antidepressant Activity by Blockade of Central Substance P Receptors, pp. 1640-1645
Mark S. Kramer; Neal Cutler; John Feighner; Ram Shrivastava; John Carman; John J. Sramek; Scott A. Reines; Guanghan Liu; Duane Snavely; Edwina Wyatt-Knowles; Jeffrey J. Hale; Sander G. Mills; Malcolm MacCoss; Christopher J. Swain; Timothy Harrison; Raymond G. Hill; Franz Hefti; Edward M. Scolnick; Margaret A. Cascieri; Gary G. Chicchi; Sharon Sadowski; Angela R. Williams; Louise Hewson; David Smith; Emma J. Carlson; Richard J. Hargreaves; Nadia M. J. Rupniak

Reports

A "Green" Route to Adipic Acid: Direct Oxidation of Cyclohexenes with 30 Percent Hydrogen Peroxide, pp. 1646-1647
Kazuhiko Sato; Masao Aoki; Ryoji Noyori

Onset of Catalytic Activity of Gold Clusters on Titania with the Appearance of Nonmetallic Properties, pp. 1647-1650
M. Valden; X. Lai; D. W. Goodman

Long-Range Electrostatic Trapping of Single-Protein Molecules at a Liquid- Solid Interface, pp. 1650-1653
Xiao-Hong Nancy Xu; Edward S. Yeung

Design of Organic Molecules with Large Two-Photon Absorption Cross Sections, pp. 1653-1656
Marius Albota; David Beljonne; Jean-Luc Brédas; Jeffrey E. Ehrlich; Jia-Ying Fu; Ahmed A. Heikal; Samuel E. Hess; Thierry Kogej; Michael D. Levin; Seth R. Marder; Dianne McCord-Maughon; Joseph W. Perry; Harald Röckel; Mariacristina Rumi; Girija Subramaniam; Watt W. Webb; Xiang-Li Wu; Chris Xu

Detection and Modeling of NonTidal Oceanic Effects on Earth's Rotation Rate, pp. 1656-1659
Steven L. Marcus; Yi Chao; Jean O. Dickey; Pascal Gegout

Energetics of Amino Acid Synthesis in Hydrothermal Ecosystems, pp. 1659-1662
J. P. Amend; E. L. Shock

Crystal Structure of the Catalytic Domain of Human Plasmin Complexed with Streptokinase, pp. 1662-1665
Xiaoqiang Wang; Xinli Lin; Jeffrey A. Loy; Jordan Tang; Xuejun C. Zhang

Grain Feeding and the Dessemination of Acid-Resistant Escherichia coli from Cattle, pp. 1666-1668
Francisco Diez-Gonzalez; Todd R. Callaway; Menas G. Kizoulis; James B. Russell

MP1: A MEK Binding Partner That Enhances Enzymatic Activation of the MAP Kinase Cascade, pp. 1668-1671
Hans J. Schaeffer; Andrew D. Catling; Scott T. Eblen; Lara S. Collier; Anke Krauss; Michael J. Weber

A Mammalian Scaffold Complex That Selectively Mediates MAP Kinase Activation, pp. 1671-1674
Alan J. Whitmarsh; Julie Cavanagh; Cathy Tournier; Jun Yasuda; Roger J. Davis

Enhanced Phosphorylation of p53 by ATM in Response to DNA Damage, pp. 1674-1677
S. Banin; L. Moyal; S.-Y. Shieh; Y. Taya; C. W. Anderson; L. Chessa; N. I. Smorodinsky; C. Prives; Y. Reiss; Y. Shiloh; Y. Ziv

Activation of the ATM Kinase by Ionizing Radiation and Phosphorylation of p53, pp. 1677-1679
Christine E. Canman; Dae-Sik Lim; Karlene A. Cimprich; Yoichi Taya; Katsuyuki Tamai; Kazuyasu Sakaguchi; Ettore Appella; Michael B. Kastan; Janet D. Siliciano

NF-κB Antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to Suppress Caspase-8 Activation, pp. 1680-1683
Cun-Yu Wang; Marty W. Mayo; Robert G. Korneluk; David V. Goeddel; Albert S. Baldwin Jr.

Biological Action of Leptin as an Angiogenic Factor, pp. 1683-1686
M. Rocio Sierra-Honigmann; Anjali K. Nath; Chiaki Murakami; Guillermo García-Cardeña; Andreas Papapetropoulos; William C. Sessa; Lisa A. Madge; Jeffrey S. Schechner; Michael B. Schwabb; Peter J. Polverini; Jaime R. Flores-Riveros

Disruption of a Neuropeptide Gene, flp-1, Causes Multiple Behavioral Defects in Caenorhabditis elegans, pp. 1686-1690
Laura S. Nelson; Marc L. Rosoff; Chris Li

Prevention of Cardiac Hypertrophy in Mice by Calcineurin Inhibition, pp. 1690-1693
Mark A. Sussman; Hae W. Lim; Natalie Gude; Tyler Taigen; Eric N. Olson; Jeffrey Robbins; Melissa C. Colbert; Antonio Gualberto; David F. Wieczorek; Jeffery D. Molkentin

Back Matter (63 pp.)

Previous Issue: New Series, Vol. 281, No. 5382, Sep. 4, 1998
Next Issue: New Series, Vol. 281, No. 5384, Sep. 18, 1998

Previous Issue: New Series, Vol. 281, No. 5383, Sep. 11, 1998
Next Issue: New Series, Vol. 281, No. 5385, Sep. 25, 1998

Front Matter (27 pp.)
Netwatch, p. 1763
Jocelyn Kaiser

News

News of the Week

NIH to Produce a 'Working Draft' of the Genome by 2001, pp. 1774-1775
Eliot Marshall

Traces of Ancient Mariners Found in Peru, pp. 1775+1777
Heather Pringle

Strict Rules Rile Indian Scientists, pp. 1777-1778
Pallava Bagla

ScienceScope, pp. 1777+1779
Graduate Admissions Down for Minorities, p. 1778
Marcia Barinaga

A Record Grant for College Programs, p. 1779
Jennifer Couzin

China Sets Rules for Foreign Collaboration, pp. 1779-1780
Li Hui

Impact of Primate Losses Estimated, pp. 1780-1781
Jocelyn Kaiser

Fighting Corruption in the Quantum World, p. 1781
Andrew Watson

NRC Seeks Boost for Base, Special Projects, pp. 1781+1783
Wayne Kondro

Fast Chemistry Snares Stray Plutonium Isotope, p. 1783
Robert F. Service

News Focus

Assembling the World's Biggest Library on Your Desktop, pp. 1784-1786
Joseph Alper

A Closer Look at SNPs Suggests Difficulties, pp. 1787-1789
Elizabeth Pennisi

More SNPs on the Way, p. 1788
Ken Garber

Software Helps Australia Manage Forest Debate, pp. 1789+1791
Elizabeth Finkel

From Supermarket Boss to Science Minister, pp. 1792-1793
Nigel Williams

A Sweet Way to Keep Proteins Safe, p. 1793
Carol Potera

Random Samples, p. 1795
Jennifer Couzin

Essays on Science and Society

A Personal Journey Through Genetics and Civil Rights, pp. 1796-1797
David Suzuki

Science's Compass

Editorial

Balancing the Research Portfolio, p. 1803
Wm. A. Wulf

Letters

Patent Income, p. 1805
Allen D. Roses

Solution to a Conservation Problem?, p. 1805
Frank A. von Hippel

Tobacco: Who Pays Whom?, pp. 1805-1806
Steve Milloy; Gio Batta Gori

Estimating the CO₂ Uptake in Europe, p. 1806
Philippe Martin

Big Spenders?, pp. 1806-1807
Eric Arnett; Robert M. May

NRC on Global Change, pp. 1807-1808
G. James Collatz; Yoram Kaufman

Native Coral, pp. 1808-1809
Mac Chapin; Peter R. Jutro

Corrections and Clarifications: New Timepiece has a Familiar Ring, p. 1809
Corrections and Clarifications: How a Growth Control Path Takes a Wrong Turn to Cancer, p. 1809
Corrections and Clarifications: Under Pressure, Deuterium Gets into Quite a State, p. 1809

Policy Forum

The Swiss Vote on Gene Technology, pp. 1810-1811
Gottfried Schatz

Books and New Media

On the Ontology and Origin of Species, pp. 1812-1813
Metaphysics and the Origin of Species.
Michael T. Ghiselin

Review author[s]: Richard M. Burian

Rescued Account of a Vanished People, pp. 1813-1814
Chronicle of the Guayaki Indians.
Pierre Clastres; Paul Auster

Review author[s]: Gustavo Politis

Making Multimedia, p. 1814
Review author[s]: Hamid Ghanadan

Perspectives

Shedding Light on Black Holes, pp. 1815-1816
Mark Reid

Turbulence and Sheared Flow, pp. 1816-1817
Keith H. Burrell

Telomeres-Unsticky Ends, pp. 1818-1819
David Shore

Tech.Sight

Genetic Variation as a Guide to Drug Development, pp. 1820-1821
Patrick W. Kleyn; Elliot S. Vesell

E-Mail Trojan Horses, p. 1822
Richard Peters; Robert Sikorski

Two-Hybridzyme, pp. 1822-1823
Robert Sikorski; Richard Peters

Metastasis in Eggs, p. 1823
Robert Sikorski; Richard Peters

Research

Research Article

Overview and Initial Results of the Very Long Baseline Interferometry Space Observatory Programme, pp. 1825-1829
H. Hirabayashi; H. Hirosawa; H. Kobayashi; Y. Murata; P. G. Edwards; E. B. Fomalont; K. Fujisawa; T. Ichikawa; T. Kii; J. E. J. Lovell; G. A. Moellenbrock; R. Okayasu; M. Inoue; N. Kawaguchi; S. Kameno; K. M. Shibata; Y. Asaki; T. Bushimata; S. Enome; S. Horiuchi; T. Miyaji; T. Umemoto; V. Migenes; K. Wajima; J. Nakajima; M. Morimoto; J. Ellis; D. L. Meier; D. W. Murphy; R. A. Preston; J. G. Smith; S. J. Tingay; D. L. Traub; R. D. Wietfeldt; J. M. Benson; M. J. Claussen; C. Flatters; J. D. Romney; J. S. Ulvestad; L. R. D'Addario; G. I. Langston; A. H. Minter; B. R. Carlson; P. E. Dewdney; D. L. Jauncey; J. E. Reynolds; A. R. Taylor; P. M. McCulloch; W. H. Cannon; L. I. Gurvits; A. J. Mioduszewski; R. T. Schilizzi; R. S. Booth

Reports

Quebrada Jaguay: Early South American Maritime Adaptations, pp. 1830-1832
Daniel H. Sandweiss; Heather McInnis; Richard L. Burger; Asuncion Cano; Bernardino Ojeda; Rolando Paredes; Maria del Carmen Sandweiss; Michael D. Glascock

Early Maritime Economy and El Niño Events at Quebrada Tacahuay, Peru, pp. 1833-1835
David K. Keefer; Susan D. deFrance; Michael E. Moseley; James B. Richardson III; Dennis R. Satterlee; Amy Day-Lewis

Turbulent Transport Reduction by Zonal Flows: Massively Parallel Simulations, pp. 1835-1837
Z. Lin; T. S. Hahm; W. W. Lee; W. M. Tang; R. B. White

Implications of Mars Pathfinder Data for the Accretion History of the Terrestrial Planets, pp. 1838-1840
Constance M. Bertka; Yingwei Fei

Forest Fires: An Example of Self-Organized Critical Behavior, pp. 1840-1842
Bruce D. Malamud; Gleb Morein; Donald L. Turcotte

Molecular Assembly and Encapsulation Directed by Hydrogen-Bonding Preferences and the Filling of Space, pp. 1842-1845
Tomas Martin; Ulrike Obst; Julius Rebek Jr.

Inhibition of Xenoreactive Natural Antibody Production by Retroviral Gene Therapy, pp. 1845-1847
Jennifer L. Bracy; David H. Sachs; John Iacomini

Dendritic Integration and Its Role in Computing Image Velocity, pp. 1848-1850
Sandra Single; Alexander Borst

Aggregation and Motor Neuron Toxicity of an ALS-Linked SOD1 Mutant Independent from Wild-Type SOD1, pp. 1851-1854
Lucie I. Bruijn; Megan K. Houseweart; Shinsuke Kato; Karen L. Anderson; Scott D. Anderson; Eisaku Ohama; Andrew G. Reaume; Rick W. Scott; Don W. Cleveland

Regulation of Meiotic S Phase by Ime2 and a Clb5,6-Associated Kinase in Saccharomyces cerevisiae, pp. 1854-1857
Léon Dirick; Loretta Goetsch; Gustav Ammerer; Breck Byers

Fertilization Defects in Sperm from Mice Lacking Fertilin β, pp. 1857-1859
Chunghee Cho; Donna O'Dell Bunch; Jean-Emmanuel Faure; Eugenia H. Goulding; Edward M. Eddy; Paul Primakoff; Diana G. Myles

Activation of Apoptosis Signal-Regulating Kinase 1 (ASK1) by the Adapter Protein Daxx, pp. 1860-1863
Howard Y. Chang; Hideki Nishitoh; Xiaolu Yang; Hidenori Ichijo; David Baltimore

Promotion of Dendritic Growth by CPG15, an Activity-Induced Signaling Molecule, pp. 1863-1866
Elly Nedivi; Gang-Yi Wu; Hollis T. Cline

Back Matter (46 pp.)

Previous Issue: New Series, Vol. 281, No. 5383, Sep. 11, 1998
Next Issue: New Series, Vol. 281, No. 5385, Sep. 25, 1998

Previous Issue: New Series, Vol. 281, No. 5384, Sep. 18, 1998
Next Issue: New Series, Vol. 282, No. 5386, Oct. 2, 1998

Front Matter (33 pp.)
NetWatch, p. 1919
Jocelyn Kaiser

News

News of the Week

Raising the Stakes in the Race for New Malaria Drugs, p. 1930
Jocelyn Kaiser

Semiconductor Beacons Light Up Cell Structures, pp. 1930-1931
Robert F. Service

Kenya Parks Chief Ousted-Again, pp. 1931+1933
David Malakoff

Canada to Draw Up Strategic Plans, pp. 1933-1934
Wayne Kondro

ScienceScope, pp. 1933+1935

News

News of the Week

Lasker Awards go to Cancer Researchers, p. 1934
Jennifer Couzin

300-Year-Old RGO Finally to Close, pp. 1934-1935
Nigel Williams

NSF Eyes Biodiversity Monitoring Network, pp. 1935-1936
Jeffrey Mervis

Harvard Tops in Scientific Impact, p. 1936
Amy Adams

A Biomolecule Building Block from Vents, pp. 1936-1937
Robert F. Service

Panel Calls for Science-Savvy Diplomats, pp. 1937+1939
David Malakoff

Size of Indian Blasts Still Disputed, p. 1939
Pallava Bagla; Eliot Marshall

Two More Scientists Died in Swissair Crash, p. 1939

News Focus

Seeking a Snapshot of an Alien World, pp. 1940-1942
Andrew Watson

Fly Development Genes Lead to Immune Find, pp. 1942-1944
Gretchen Vogel

The Biocomplex World of Rita Colwell, pp. 1944-1945+1947
Jeffrey Mervis

Fractals Reemerge in the New Math of the Internet, pp. 1947-1948
Gary Taubes

Among Global Thermometers, Warming Still Wins Out, pp. 1948-1949
Richard A. Kerr

Random Samples, p. 1951
Gretchen Vogel

Essays on Science and Society

Protecting Medicine in the 21st Century, pp. 1952-1953
C. Everett Koop

Science's Compass

Editorial

A Revolution in Evolution, p. 1959
Jim Bull; Holly Wichman

Letters

Telescope Costs, p. 1961
Riccardo Giacconi

Cleaning CJD-Contaminated Instruments, p. 1961
Laura Manuelidis

Salt Wars, pp. 1961-1963
Claude Lenfant; Gary Taubes; Jennifer Reed; Sol Sepsenwol; Matthias Barton; Thomas F. Luscher; Ton J. Rabelink; Abraham Aviv; Jonathan Katz

Quantum Computing, pp. 1963-1964
Amr F. Fahmy; Jonathan A. Jones

Crystallography of a Photocycle Intermediate, p. 1964
T. E. Meyer; G. Tollin; M. A. Cusanovich; Benjamin Perman; Michael Wulff; Klaas Hellingwerf; Keith Moffat

Policy Forum

Monitoring Nuclear Tests, pp. 1967-1968
Brian Barker; Michael Clark; Peter Davis; Mark Fisk; Michael Hedlin; Hans Israelsson; Vitaly Khalturin; Won-Young Kim; Keith McLaughlin; Charles Meade; John Murphy; Robert North; John Orcutt; Chris Powell; Paul G. Richards; Richard Stead; Jeffry Stevens; Frank Vernon; Terry Wallace

Books and New Media

A Skeptic's Sense of Wonder, pp. 1969-1970
Skeptics and True Believers. The Exhilarating Connection between Science and Religion
Chet Raymo

Review author[s]: W. Mark Richardson

Perspectives

How Asteroids Come to Earth, pp. 1971+1973
Richard Greenberg

Quantum Control of the Inevitable, pp. 1973-1974
Marlan O. Scully; Shi-Yao Zhu

Ants, Crops, and History, pp. 1974-1975
Jared Diamond

The Saturation Debate, pp. 1975-1976
T. V. P. Bliss

[Introduction], p. 1979
Pamela Hines; Elizabeth Culotta

Evolution of Sex

News

Why Sex? Putting Theory to the Test, pp. 1980-1982
Bernice Wuethrich

A New Look at Monogamy, pp. 1982-1983
Virginia Morell

A Genomic Battle of the Sexes, pp. 1984-1985
Elizabeth Pennisi

Review

Why Sex and Recombination?, pp. 1986-1990
N. H. Barton; B. Charlesworth

The Evolutionary Dynamics of Sex Determination, pp. 1990-1994
Ignacio Marín; Bruce S. Baker

Evolution of Gamete Recognition Proteins, pp. 1995-1998
Victor D. Vacquier

Sexual Selection, Receiver Biases, and the Evolution of Sex Differences, pp. 1999-2003
Michael J. Ryan

Sex and Conflict, pp. 2003-2008
Linda Partridge; Laurence D. Hurst

Research

Reports

Ancient Mantle in a Modern Arc: Osmium Isotopes in Izu-Bonin-Mariana Forearc Peridotites, pp. 2011-2013
Ian J. Parkinson; Chris J. Hawkesworth; Anthony S. Cohen

Semiconductor Nanocrystals as Fluorescent Biological Labels, pp. 2013-2016
Marcel Bruchez Jr.; Mario Moronne; Peter Gin; Shimon Weiss; A. Paul Alivisatos

Quantum Dot Bioconjugates for Ultrasensitive Nonisotopic Detection, pp. 2016-2018
Warren C. W. Chan; Shuming Nie

Europa's Differentiated Internal Structure: Inferences from Four Galileo Encounters, pp. 2019-2022
J. D. Anderson; G. Schubert; R. A. Jacobson; E. L. Lau; W. B. Moore; W. L. Sjogren

Origin of Multikilometer Earth-and Mars-Crossing Asteroids: A Quantitative Simulation, pp. 2022-2024
Fabio Migliorini; Patrick Michel; Alessandro Morbidelli; David Nesvorný; Vincenzo Zappalà

The Formation of Substellar Objects Induced by the Collision of Protostellar Disks, pp. 2025-2027
D. N. C. Lin; G. Laughlin; P. Bodenheimer; M. Różyczka

Bax and Adenine Nucleotide Translocator Cooperate in the Mitochondrial Control of Apoptosis, pp. 2027-2031
Isabel Marzo; Catherine Brenner; Naoufal Zamzami; Juliane M. Jürgensmeier; Santos A. Susin; Helena L. A. Vieira; Marie-Christine Prévost; Zhihua Xie; Shigemi Matsuyama; John C. Reed; Guido Kroemer

Dorsal-Ventral Signaling in the Drosophila Eye, pp. 2031-2034
Venizelos Papayannopoulos; Andrew Tomlinson; Vladislav M. Panin; Cordelia Rauskolb; Kenneth D. Irvine

The Evolution of Agriculture in Ants, pp. 2034-2038
Ulrich G. Mueller; Stephen A. Rehner; Ted R. Schultz

Impaired Spatial Learning After Saturation of Long-Term Potentiation, pp. 2038-2042
Edvard I. Moser; Kurt A. Krobert; May-Britt Moser; Richard G. M. Morris

Protein Kinase C Isotypes Controlled by Phosphoinositide 3-Kinase Through the Protein Kinase PDK1, pp. 2042-2045
J. Ann Le Good; Wolfgang H. Ziegler; Davey B. Parekh; Dario R. Alessi; Philip Cohen; Peter J. Parker

Metapopulation Dynamics, Abundance, and Distribution in a Microecosystem, pp. 2045-2047
A. Gonzalez; J. H. Lawton; F. S. Gilbert; T. M. Blackburn; I. Evans-Freke

AAAS News and Notes, pp. 2048-2049
Tiffany Ayers

Back Matter (43 pp.)

Previous Issue: New Series, Vol. 281, No. 5384, Sep. 18, 1998
Next Issue: New Series, Vol. 282, No. 5386, Oct. 2, 1998

Previous Issue: New Series, Vol. 281, No. 5385, Sep. 25, 1998
Next Issue: New Series, Vol. 282, No. 5387, Oct. 9, 1998

Front Matter (31 pp.)
NetWatch, p. 7
Jocelyn Kaiser

News

News of the Week

NIH Embraces Citizens' Council to Cool Debate on Priorities, pp. 18-19
Bruce Agnew

Leakey Back as Head of Wildlife Service, p. 19
David Malakoff

Tracks of Billion-Year-Old Animals?, pp. 19+21
Richard A. Kerr

Mexican Fires Charge Up U.S. Clouds, pp. 21-22
Robert Irion

ScienceScope, pp. 21+23

News

News of the Week

Researchers Wary of Red-Green Coalition, pp. 22-23
Robert Koenig

House Report Takes Middle Ground, pp. 23-24
David Malakoff

Distant Star's Radiation Jolts Earth's Atmosphere, p. 24
David Kestenbaum

Japan Urged to Open Up Planning for Lab, pp. 24-25
Dennis Normile

A Gray Day on a Brown Dwarf, pp. 25+27
Govert Schilling

RAC Confronts in Utero Gene Therapy Proposals, p. 27
Jennifer Couzin

News Focus

When Walls Can Talk, Plant Biologists Listen, pp. 28-29
Evelyn Strauss

New Math Speeds the Search for Protein Structures, pp. 30-31
David Kestenbaum

A Bold Plan to Re-Create a Long-Lost Siberian Ecosystem, pp. 31+33-34
Richard Stone

Iridium Accelerates Squeeze on the Spectrum, pp. 34-35
David Malakoff

Leveling the Playing Field for Scientists with Disabilities, pp. 36-37
Constance Holden

Random Samples, p. 39
Gretchen Vogel

Essays on Science and Society

Bioprospecting in an African Context, pp. 41-42
Lydia Makhubu

Science's Compass

Editorial

A Call for More Science in EPA Regulations, p. 45
William J. Madia

Letters

Chimp Research, p. 47
Steven R. Leigh; Oliver A. Ryder

Big Sky Science, p. 47
Conrad Burns

Is Oil Running Out?, pp. 47-49
Michael Toman; Joel Darmstadter; Amory B. Lovins; Richard C. Duncan; Walter Youngquist

"Bow Tie" Correction, pp. 49-50
Claire Gmachl

Cope's Rule, pp. 50-51
Paul D. Polly; John Alroy

Corrections and Clarifications: Strict Rules Rile Indian Scientists, p. 51
Corrections and Clarifications: Graduate Admissions Down for Minorities, p. 51
Corrections and Clarifications: The Paradox of Lead Poisoning Prevention, p. 51
Corrections and Clarifications: Tales Told in Lead, p. 51

Science's Compass

Policy Forum

The Human Genome Project: Reaching the Finish Line, pp. 53-54
R. Waterston; J. E. Sulston

Books and New Media

The New "Great Work", p. 55
Retroviruses.
John M. Coffin; Stephen H. Hughes; Harold E. Varmus

Review author[s]: Simon Wain-Hobson

Beyond Expert Advice, pp. 55-57
HyperNMR 2.0.
Hypercube Inc.

Review author[s]: Larry S. Daley; Kevin Ahern

Perspectives

Separating the Wheat from the Chaff, pp. 57-58
Nancy Kanwisher; Paul Downing

A Role for the Tropical Pacific, pp. 59+61
Mark A. Cane

The Seesaw Effect, pp. 61-62
Thomas F. Stocker

Review

Harnessing the Biosynthetic Code: Combinations, Permutations, and Mutations, pp. 63-68
David E. Cane; Christopher T. Walsh; Chaitan Khosla

Research

Reports

Tomographic Evidence for Localized Lithospheric Shear Along the Altyn Tagh Fault, pp. 74-76
Gérard Wittlinger; Paul Tapponnier; Georges Poupinet; Jiang Mei; Shi Danian; Georges Herquel; Frédéric Masson

Enhanced Positive Cloud-to-Ground Lightning in Thunderstorms Ingesting Smoke from Fires, pp. 77-80
Walter A. Lyons; Thomas E. Nelson; Earle R. Williams; John A. Cramer; Tommy R. Turner

Triploblastic Animals More Than 1 Billion Years Ago: Trace Fossil Evidence from India, pp. 80-83
Adolf Seilacher; Pradip K. Bose; Friedrich Pflüger

ROSAT X-ray Detection of a Young Brown Dwarf in the Chamaeleon I Dark Cloud, pp. 83-85
Ralph Neuhäuser; Fernando Comerón

Measuring the Spin Polarization of a Metal with a Superconducting Point Contact, pp. 85-88
R. J. Soulen Jr.; J. M. Byers; M. S. Osofsky; B. Nadgorny; T. Ambrose; S. F. Cheng; P. R. Broussard; C. T. Tanaka; J. Nowak; J. S. Moodera; A. Barry; J. M. D. Coey

Particle Nucleation in the Tropical Boundary Layer and Its Coupling to Marine Sulfur Sources, pp. 89-92
A. D. Clarke; D. Davis; V. N. Kapustin; F. Eisele; G. Chen; I. Paluch; D. Lenschow; A. R. Bandy; D. Thornton; K. Moore; L. Mauldin; D. Tanner; M. Litchy; M. A. Carroll; J. Collins; G. Albercook

Synchronous Climate Changes in Antarctica and the North Atlantic, pp. 92-95
E. J. Steig; E. J. Brook; J. W. C. White; C. M. Sucher; M. L. Bender; S. J. Lehman; D. L. Morse; E. D. Waddington; G. D. Clow

Solution Properties of Single-Walled Carbon Nanotubes, pp. 95-98
Jian Chen; Mark A. Hamon; Hui Hu; Yongsheng Chen; Apparao M. Rao; Peter C. Eklund; Robert C. Haddon

Ammonia Synthesis at Atmospheric Pressure, pp. 98-100
George Marnellos; Michael Stoukides

An Arabidopsis Mutant Defective in the Plastid General Protein Import Apparatus, pp. 100-103
Paul Jarvis; Lih-Jen Chen; Hsou-min Li; Charles A. Peto; Christian Fankhauser; Joanne Chory

Hepatitis C Viral Dynamics In vivo and the Antiviral Efficacy of Interferon-α Therapy, pp. 103-107
Avidan U. Neumann; Nancy P. Lam; Harel Dahari; David R. Gretch; Thelma E. Wiley; Thomas J. Layden; Alan S. Perelson

Mechanisms of Directed Attention in the Human Extrastriate Cortex as Revealed by Functional MRI, pp. 108-111
Sabine Kastner; Peter de Weerd; Robert Desimone; Leslie G. Ungerleider

A Structural Basis for Recognition of A·T and T·A Base Pairs in the Minor Groove of B-DNA, pp. 111-115
Clara L. Kielkopf; Sarah White; Jason W. Szewczyk; James M. Turner; Eldon E. Baird; Peter B. Dervan; Douglas C. Rees

A Carrot Leucine-Rich-Repeat Protein That Inhibits Ice Recrystallization, pp. 115-117
Dawn Worrall; Luisa Elias; David Ashford; Maggie Smallwood; Chris Sidebottom; Peter Lillford; Julia Telford; Chris Holt; Dianna Bowles

Role for the Target Enzyme in Deactivation of Photoreceptor G Protein In Vivo, pp. 117-121
Stephen H. Tsang; Marie E. Burns; Peter D. Calvert; Peter Gouras; Denis A. Baylor; Stephen P. Goff; Vadim Y. Arshavsky

An Antimicrobial Activity of Cytolytic T Cells Mediated by Granulysin, pp. 121-125
Steffen Stenger; Dennis A. Hanson; Rachel Teitelbaum; Puneet Dewan; Kayvan R. Niazi; Christopher J. Froelich; Tomas Ganz; Sybille Thoma-Uszynski; Agustín Melián; Christian Bogdan; Steven A. Porcelli; Barry R. Bloom; Alan M. Krensky; Robert L. Modlin

Back Matter (63 pp.)

Previous Issue: New Series, Vol. 281, No. 5385, Sep. 25, 1998
Next Issue: New Series, Vol. 282, No. 5387, Oct. 9, 1998

Previous Issue: New Series, Vol. 282, No. 5386, Oct. 2, 1998
Next Issue: New Series, Vol. 282, No. 5388, Oct. 16, 1998

Front Matter (35 pp.)
NetWatch, p. 195
Jocelyn Kaiser

News

News of the Week

NASA to Buy Research Time to Bail Out Russian Agency, pp. 206-207
David Malakoff

Optical Circuits Turn a Corner, p. 207
Andrew Watson

R&D Budget Request Reverses Long Decline, pp. 207+209
Alicia Rivera

Three Spending Bills Bolster Research, pp. 209-210
David Malakoff

ScienceScope, pp. 209+211

News

News of the Week

Geologists See Mars in the Canadian Arctic, pp. 210-211
Robert Irion

Probing the Milky Way's Black Heart, pp. 211-212
Govert Schilling

NSF Spells Out an Electronic Future, p. 212
Jeffrey Mervis

Court Hears Fight Over Safety of Lab, pp. 213+215
Dennis Normile

Cresson Told to Explain Questioned Contracts, p. 215
Nigel Williams

Bug Vanquishes Species, p. 215
Dan Ferber

News Focus

Human Rights Fades as a Cause for Scientists, pp. 216-219
James Glanz

Molecular Methods Fire Up the Hunt for Emerging Pathogens, pp. 219-221
Michael Balter

How Matter Can Melt at Absolute Zero, pp. 221+223-224
David Voss

New Clues to Movement Control and Vision, pp. 224-225
Ingrid Wickelgren

Random Samples, p. 227
Constance Holden

Essays on Science and Society

The Mouse with the Flying Bicycle, pp. 229-230
John Lynch

Science's Compass

Editorial

How to Change the University, p. 237
Michael S. Gazzaniga

Letters

Nature Medicine's Reply Policy, p. 239
Adrian J. Ivinson

Airborne Particulate Matter, p. 239
Forrest M. Mims III

Great Ape Phenome Project?, pp. 239-240
Ajit Varki; Christopher Wills; David Perlmutter; David Woodruff; Fred Gage; James Moore; Katerina Semendeferi; Kurt Benirshke; Robert Katzman; Russell Doolittle; Theodore Bullock

Science Education Reform, pp. 240-242
John A. Moore; Glenn T. Seaborg; Leon M. Lederman; Marjorie G. Bardeen

5200-Year-Old Acupuncture in Central Europe?, pp. 242-243
Leopold Dorfer; Maximilian Moser; Konrad Spindler; Frank Bahr; Eduard Egarter-Vigl; Gottfried Dohr

Maternal Investment in Human Brain Growth, p. 243
Rose E. Frisch

Typographical Error, p. 243
Georg F. Weber; Samy Ashkar; Harvey Cantor; Melvin J. Glimcher

Corrections and Clarifications: A Biomolecule Building Block from Vents, p. 243
Corrections and Clarifications: Assembling the World's Biggest Library on Your Desktop, p. 243
Corrections and Clarifications: Solution to a Conservation Problem?, p. 243
Corrections and Clarifications: Societies Leap Into California Standards Fray, p. 243
Corrections and Clarifications: Populations as 'Species-in-Waiting'?, p. 243

Science's Compass

Policy Forum

Outcomes Research: Measuring the End Results of Health Care, pp. 245-246
Carolyn M. Clancy; John M. Eisenberg

Books and New Media

The Public and the Quake That Wasn't, p. 247
Earthquake Fears, Predictions, and Preparations in Mid-America.
John E. Farley

Review author[s]: Seth Stein

Model Metaorganism, p. 248
Volvox. Molecular-Genetic Origins of Multicellularity and Cellular Differentiation.
David L. Kirk

Review author[s]: Graham Bell

Perspectives

A New Twist, p. 249
Matt Visser

Ribozyme Architectural Diversity Made Visible, pp. 251-252
Eric Westhof; François Michel

A Plant's Dilemma, pp. 252-253
Erwin Grill; Hubert Ziegler

Research

Research Article

A Preorganized Active Site in the Crystal Structure of the Tetrahymena Ribozyme, pp. 259-264
Barbara L. Golden; Anne R. Gooding; Elaine R. Podell; Thomas R. Cech

Reports

The Chemistry of Water on Alumina Surfaces: Reaction Dynamics from First Principles, pp. 265-268
Kenneth C. Hass; William F. Schneider; Alessandro Curioni; Wanda Andreoni

Past Temperatures Directly from the Greenland Ice Sheet, pp. 268-271
D. Dahl-Jensen; K. Mosegaard; N. Gundestrup; G. D. Clow; S. J. Johnsen; A. W. Hansen; N. Balling

Direct Measurement of Femtomoles of Osmium and the ¹⁸⁷ Os/ ¹⁸⁶ Os Ratio in Seawater, pp. 272-274
Sylvain Levasseur; Jean-Louis Birck; Claude J. Allègre

Experimental Demonstration of Guiding and Bending of Electromagnetic Waves in a Photonic Crystal, pp. 274-276
Shawn-Yu Lin; Edmund Chow; Vince Hietala; Pierre R. Villeneuve; J. D. Joannopoulos

Organic Carbon Fluxes and Ecological Recovery from the Cretaceous-Tertiary Mass Extinction, pp. 276-279
Steven D'Hondt; Percy Donaghay; James C. Zachos; Danielle Luttenberg; Matthias Lindinger

Climate Change Record in Subsurface Temperatures: A Global Perspective, pp. 279-281
Henry N. Pollack; Shaopeng Huang; Po-Yu Shen

Isolation of Acidophilic Methane-Oxidizing Bacteria from Northern Peat Wetlands, pp. 281-284
Svetlana N. Dedysh; Nicolai S. Panikov; Werner Liesack; Regine Großkopf; Jizhong Zhou; James M. Tiedje

Alterations of the PPP2R1B Gene in Human Lung and Colon Cancer, pp. 284-287
Steven Siqing Wang; Edward D. Esplin; Jia Ling Li; Liying Huang; Adi Gazdar; John Minna; Glen A. Evans

Role of Farnesyltransferase in ABA Regulation of Guard Cell Anion Channels and Plant Water Loss, pp. 287-290
Zhen-Ming Pei; Majid Ghassemian; Christine M. Kwak; Peter McCourt; Julian I. Schroeder

Cell Surface Trafficking of Fas: A Rapid Mechanism of p53-Mediated Apoptosis, pp. 290-293
Martin Bennett; Kirsty Macdonald; Shiu-Wan Chan; J. Paul Luzio; Robert Simari; Peter Weissberg

Bifurcation of Lipid and Protein Kinase Signals of PI3Kγ to the Protein Kinases PKB and MAPK, pp. 293-296
Tzvetanka Bondeva; Luciano Pirola; Ginette Bulgarelli-Leva; Ignacio Rubio; Reinhard Wetzker; Matthias P. Wymann

Controlling Gene Expression in Living Cells Through Small Molecule-RNA Interactions, pp. 296-298
Geoffrey Werstuck; Michael R. Green

Transition from Moderate to Excessive Drug Intake: Change in Hedonic Set Point, pp. 298-300
S. H. Ahmed; G. F. Koob

Back Matter (68 pp.)

Previous Issue: New Series, Vol. 282, No. 5386, Oct. 2, 1998
Next Issue: New Series, Vol. 282, No. 5388, Oct. 16, 1998

Previous Issue: New Series, Vol. 282, No. 5387, Oct. 9, 1998
Next Issue: New Series, Vol. 282, No. 5389, Oct. 23, 1998

Front Matter (26 pp.)
Netwatch, p. 375
Jocelyn Kaiser

News

News of the Week

Possibly Vast Greenhouse Gas Sponge Ignites Controversy, pp. 386-387
Jocelyn Kaiser

California Adopts Controversial Standards, pp. 387+389
Gretchen Vogel

Tight Budget Could Shut Down MIT Accelerator, pp. 389-390
David Malakoff

ScienceScope, pp. 389+391
Sea Otter Declines Blamed on Hungry Killers, pp. 390-391
Jocelyn Kaiser

Deep Chill Triggers Record Ozone Hole, p. 391
Richard A. Kerr

Seeing the Universe's Red Dawn, p. 392
Ann Finkbeiner

1999 Budget: One Step Forward, Two Back, pp. 392-393
Elizabeth Pennisi

Male Mating Blocks New Cuckoo Species, p. 393
Virginia Morell

Recovered SOHO Passes Health Check, pp. 393+395
Alexander Hellemans

Planet Hunters Become Weight Watchers, p. 395
Govert Schilling

News Focus

Microchip Arrays Put DNA on the Spot, pp. 396-399
Robert F. Service

Coming Soon: The Pocket DNA Sequencer, pp. 399-401
Robert F. Service

Fomenting a Revolution, in Miniature, pp. 402-403+405
Ivan Amato

Random Samples, p. 407
Constance Holden

Essays on Science and Society

Alleviating Poverty Through Technology, pp. 409-410
Muhammad Yunus

Science's Compass

Editorial

Regulating Human Cloning, p. 413
Paul Berg; Maxine Singer

Letters

Environmental Decision-Making, p. 415
Peter D. Saundry

Animal Experimentation Rules in India, p. 415
Sandip K. Basu; Satyajit Rath

DOD: A Critical Funder and Risk-Taker, p. 415
Rustum Roy

Standards for Engineer Witnesses, pp. 415-416
Michael D. Green; George W. Pearsall; Norman W. Edmund

The Copyright Issue, pp. 416-417
E. Peter Geiduschek; Jens Bammel

Corrections and Clarifications: Cope's Rule, p. 417
Corrections and Clarifications: Fly Development Genes Lead to Immune Find, p. 417
Corrections and Clarifications: Just Add Water Vapor, p. 417
Corrections and Clarifications: Inactivation of a Serotoningated Ion Channel by a Polypeptide Toxin from Marine Snails, p. 417
Corrections and Clarifications: Henneman's Size Principle: The Right Name, p. 417
Corrections and Clarifications: Tracking Down Mutations that Can Stop the Heart, p. 417
Corrections and Clarifications: Climate-Ocean Variability and Ecosystem Response in the Northeast Pacific, p. 417

Science's Compass

Policy Forum

Demographic Consequences of Declining Fertility, pp. 419-420
John Bongaarts

Books and New Media

Science and Civics, Still Immiscible, p. 421
Science in Public. Communication, Culture, and Credibility.
Jane Gregory; Steve Miller

Review author[s]: Kai N. Lee

A Modest Maker of Modern Physics, p. 422
The Neutron and the Bomb. A Biography of Sir James Chadwick.
Andrew Brown

Review author[s]: Lorna Arnold

Perspectives

Making Sense of Active Galaxies, pp. 423-424
Daniel W. Weedman

Developmental Options, pp. 424-425
Ken Shortman; Eugene Maraskovsky

How to Compact DNA, pp. 425+427
Andrew W. Murray

Future of the West Antarctic Ice Sheet, pp. 428-429
Robert Bindschadler

Tech.Sight

RNAi in C. elegans: Soaking in the Genome Sequence, pp. 430-431
Hiroaki Tabara; Alla Grishok; Craig C. Mello

Turning the Big Five-O, p. 432
Robert Sikorski; Richard Peters

The Art of Bubble Making, pp. 432-433
Richard Peters; Robert Sikorski

Muscular Electronics, p. 433
Richard Peters; Robert Sikorski

Pocket Laboratory, p. 433
Robert Sikorski; Richard Peters

Research

Reports

Carbon Dioxide Emission from European Estuaries, pp. 434-436
Michel Frankignoulle; Gwenaël Abril; Alberto Borges; Isabelle Bourge; Christine Canon; Bruno Delille; Emile Libert; Jean-Marie Théate

A Short Circuit in Thermohaline Circulation: A Cause for Northern Hemisphere Glaciation?, pp. 436-438
N. W. Driscoll; G. H. Haug

Changes in the Carbon Balance of Tropical Forests: Evidence from Long-Term Plots, pp. 439-442
Oliver L. Phillips; Yadvinder Malhi; Niro Higuchi; William F. Laurance; Percy V. Núñez; Rodolfo M. Vásquez; Susan G. Laurance; Leandro V. Ferreira; Margaret Stern; Sandra Brown; John Grace

A Large Terrestrial Carbon Sink in North America Implied by Atmospheric and Oceanic Carbon Dioxide Data and Models, pp. 442-446
S. Fan; M. Gloor; J. Mahlman; S. Pacala; J. Sarmiento; T. Takahashi; P. Tans

North Atlantic Oscillation Dynamics Recorded in Greenland Ice Cores, pp. 446-449
C. Appenzeller; T. F. Stocker; M. Anklin

Two-Dimensional Magnetic Particles, pp. 449-451
C. Stamm; F. Marty; A. Vaterlaus; V. Weich; S. Egger; U. Maier; U. Ramsperger; H. Fuhrmann; D. Pescia

Oxygen Reservoirs in the Early Solar Nebula Inferred from an Allende CAI, pp. 452-455
Edward D. Young; Sara S. Russell

Antarctic Elevation Change from 1992 to 1996, pp. 456-458
Duncan J. Wingham; Andrew J. Ridout; Remko Scharroo; Robert J. Arthern; C. K. Shum

Migration of Fluids Beneath Yellowstone Caldera Inferred from Satellite Radar Interferometry, pp. 458-462
Charles Wicks Jr.; Wayne Thatcher; Daniel Dzurisin

Induced Massive Star Formation in the Trifid Nebula?, pp. 462-465
J. Cernicharo; B. Lefloch; P. Cox; D. Cesarsky; C. Esteban; F. Yusef-Zadeh; D. I. Méndez; J. Acosta-Pulido; R. J. García López; A. Heras

Exceeding 5000-Fold Concentration of Dilute Analytes in Micellar Electrokinetic Chromatography, pp. 465-468
Joselito P. Quirino; Shigeru Terabe

Increased Vascularization in Mice Overexpressing Angiopoietin-1, pp. 468-471
Chitra Suri; Joyce McClain; Gavin Thurston; Donald M. McDonald; Hao Zhou; Eben H. Oldmixon; Thomas N. Sato; George D. Yancopoulos

Host-Race Formation in the Common Cuckoo, pp. 471-472
Karen Marchetti; Hiroshi Nakamura; H. Lisle Gibbs

Killer Whale Predation on Sea Otters Linking Oceanic and Nearshore Ecosystems, pp. 473-476
J. A. Estes; M. T. Tinker; T. M. Williams; D. F. Doak

Induction of Antigen-Specific Cytotoxic T Lymphocytes in Humans by a Malaria DNA Vaccine, pp. 476-480
Ruobing Wang; Denise L. Doolan; Thong P. Le; Richard C. Hedstrom; Kevin M. Coonan; Yupin Charoenvit; Trevor R. Jones; Peter Hobart; Michal Margalith; Jennifer Ng; Walter R. Weiss; Martha Sedegah; Charles de Taisne; Jon A. Norman; Stephen L. Hoffman

Differentiation of Monocytes into Dendritic Cells in a Model of Transendothelial Trafficking, pp. 480-483
Gwendalyn J. Randolph; Sylvie Beaulieu; Serge Lebecque; Ralph M. Steinman; William A. Muller

An Integrated Nanoliter DNA Analysis Device, pp. 484-487
Mark A. Burns; Brian N. Johnson; Sundaresh N. Brahmasandra; Kalyan Handique; James R. Webster; Madhavi Krishnan; Timothy S. Sammarco; Piu M. Man; Darren Jones; Dylan Heldsinger; Carlos H. Mastrangelo; David T. Burke

Phosphorylation and Activation of 13S Condensin by Cdc2 In vitro, pp. 487-490
Keiji Kimura; Michiko Hirano; Ryuji Kobayashi; Tatsuya Hirano

Inhibition of Toxic Epidermal Necrolysis by Blockade of CD95 with Human Intravenous Immunoglobulin, pp. 490-493
Isabelle Viard; Philippe Wehrli; Roberto Bullani; Pascal Schneider; Nils Holler; Denis Salomon; Thomas Hunziker; Jean-Hilaire Saurat; Jürg Tschopp; Lars E. French

Two Modes of Survival of Fission Yeast Without Telomerase, pp. 493-496
Toru M. Nakamura; Julia Promisel Cooper; Thomas R. Cech

Back Matter (84 pp.)

Previous Issue: New Series, Vol. 282, No. 5387, Oct. 9, 1998
Next Issue: New Series, Vol. 282, No. 5389, Oct. 23, 1998

Previous Issue: New Series, Vol. 282, No. 5388, Oct. 16, 1998
Next Issue: New Series, Vol. 282, No. 5390, Oct. 30, 1998

Front Matter (54 pp.)
NetWatch, p. 587
Jocelyn Kaiser

News

News of the Week

NIH Wins Big as Congress Lumps Together Eight Bills, pp. 598-599
David Malakoff; Eliot Marshall

Insect Wings Point to Early Sophistication, pp. 599+601
Gretchen Vogel

Fossils Challenge Age of Billion-Year-Old Animals, pp. 601-602
Richard A. Kerr

ScienceScope, pp. 601+603
Particle Decays Reveal Arrow of Time, pp. 602-603
David Kestenbaum

Young Dinos Grew Up Fast, pp. 603-604
Erik Stokstad

From Fat-Free Mice, the Skinny on Diabetes, p. 604
Trisha Gura

NASA Craft to Take the Controls in Flight, pp. 604-605
Dennis Normile

Quantum Encryption Takes First Step to Orbit, pp. 605+607
Andrew Watson

Researchers Rail Against CNRS Reforms, p. 607
Michael Balter

News Focus

Chemical Industry Rushes Toward Greener Pastures, pp. 608-610
Robert F. Service

Nine Scientists Get the Call to Stockholm, pp. 610-611+613-614
Nigel Williams; Ivan Amato; James Glanz; David Malakoff

Researchers Go Natural in Visual Studies, pp. 614-616
Marcia Barinaga

The Great DOE Land Rush?, pp. 616-617
Kathryn S. Brown

Random Samples, p. 619
Constance Holden

Essays on Science and Society

Supporting Science, pp. 621-622
Nathan Myhrvold

Science's Compass

Editorial

Genomics Research and Human Subjects, p. 625
Henry T. Greely

Letters

Plant Biology and the Nobel Prize, p. 627
Hans Kende

Fossil Discoveries in India, p. 627
R. J. Azmi

Dismissal of Faculty, pp. 627-628
Gerald Soslau; Hagai Rottenberg; Mark Stearns

Scientist-Diplomats, p. 628
Edward McSweegan

Among the Guayaki (Ache), p. 628
Review author[s]: Kim Hill

Fishing Expeditions, pp. 628-629
John N. Weinstein

Attracting Minorities to Science, pp. 629+631
Harold Amos; Alex Small

Let the Market Decide, p. 631
Ken Frazier

Policy Forum

Cocaine Exposure and Children: The Meaning of Subtle Effects, pp. 633-634
Barry M. Lester; Linda L. LaGasse; Ronald Seifer

Books and New Media

How to Make Sense of Sequences, pp. 635-636
Bioinformatics. A Practical Guide to the Analysis of Genes and Proteins.
Andreas D. Baxevanis; B. F. Francis Ouellette

Review author[s]: Carol J. Bult

A Handler for Big Data, p. 636
HiQ.
National Instruments Corporation

Review author[s]: Tony Cass

Perspectives

A Tale of Two Cities, pp. 637-638
Carlton M. Caves

Chlamydia: Old Ideas Crushed, New Mysteries Bared, pp. 638-639
Thomas Hatch

Knowledge of Number: Its Evolution and Ontogeny, pp. 641-642
Susan Carey

A Glimpse of the Holy Grail?, pp. 642-643
Herman J. C. Berendsen

Innocent Inclusions, p. 643
Katrina L. Kelner

A Genome Sampler

[Introduction], p. 651
Barbara R. Jasny; Pamela J. Hines

News

A Bonanza for Plant Genomics, pp. 652-654
Elizabeth Pennisi

DNA Studies Challenge the Meaning of Race, pp. 654-655
Eliot Marshall

Viewpoint

Plant Comparative Genetics After 10 Years, pp. 656-659
M. D. Gale; K. M. Devos

Databases in Genomic Research, pp. 659-661
William M. Gelbart

Arabidopsis thaliana: A Model Plant for Genome Analysis, pp. 662+679-682
David W. Meinke; J. Michael Cherry; Caroline Dean; Steven D. Rounsley; Maarten Koornneef

Genome Maps 9. Arabidopsis thaliana, pp. 671-678
Seung Yon Rhee; Shuai Weng; David Flanders; J. Michael Cherry; Caroline Dean; Clare Lister; Mary Anderson; Maarten Koornneef; David W. Meinke; Todd Nickle; Kelsey Smith; Steven D. Rounsley

A Genome Sampler

Review

New Goals for the U.S. Human Genome Project: 1998-2003, pp. 682-689
Francis S. Collins; Ari Patrinos; Elke Jordan; Aravinda Chakravarti; Raymond Gesteland; LeRoy Walters; Members of the DOE and NIH Planning Groups

Research

Research Articles

The Transcriptional Program of Sporulation in Budding Yeast, pp. 699-705
S. Chu; J. DeRisi; M. Eisen; J. Mulholland; D. Botstein; P. O. Brown; I. Herskowitz

Unconditional Quantum Teleportation, pp. 706-709
A. Furusawa; J. L. Sørensen; S. L. Braunstein; C. A. Fuchs; H. J. Kimble; E. S. Polzik

Reports

Three-Dimensional Structure at the Base of the Mantle Beneath the Central Pacific, pp. 718-720
Ludovic Bréger; Barbara Romanowicz

Pressure-Induced Landau-Type Transition in Stishovite, pp. 720-724
Denis Andrault; Guillaume Fiquet; François Guyot; Michael Hanfland

Thermodynamics of Calcite Growth: Baseline for Understanding Biomineral Formation, pp. 724-727
H. Henry Teng; Patricia M. Dove; Christine A. Orme; James J. de Yoreo

Predictability in the Midst of Chaos: A Scientific Basis for Climate Forecasting, pp. 728-731
J. Shukla

Climate and Groundwater Recharge During the Last Glaciation in an Ice-Covered Region, pp. 731-734
Urs Beyerle; Roland Purtschert; Werner Aeschbach-Hertig; Dieter M. Imboden; Heinz H. Loosli; Rainer Wieler; Rolf Kipfer

Self-Organized Growth of Three-Dimensional Quantum-Dot Crystals with fcc- Like Stacking and a Tunable Lattice Constant, pp. 734-737
G. Springholz; V. Holy; M. Pinczolits; G. Bauer

Rapid Identification of Subtype-Selective Agonists of the Somatostatin Receptor Through Combinatorial Chemistry, pp. 737-740
Susan P. Rohrer; Elizabeth T. Birzin; Ralph T. Mosley; Scott C. Berk; Steven M. Hutchins; Dong-Ming Shen; Yusheng Xiong; Edward C. Hayes; Rupa M. Parmar; Forrest Foor; Sudha W. Mitra; Sylvia J. Degrado; Min Shu; John M. Klopp; Sheng-Jian Cai; Allan Blake; Wanda W. S. Chan; Alex Pasternak; Lihu Yang; Arthur A. Patchett; Roy G. Smith; Kevin T. Chapman; James M. Schaeffer

Pathways to a Protein Folding Intermediate Observed in a 1-Microsecond Simulation in Aqueous Solution, pp. 740-744
Yong Duan; Peter A. Kollman

A Physical Map of 30,000 Human Genes, pp. 744-746
P. Deloukas; G. D. Schuler; G. Gyapay; E. M. Beasley; C. Soderlund; P. Rodriguez-Tomé; L. Hui; T. C. Matise; K. B. McKusick; J. S. Beckmann; S. Bentolila; M.-T. Bihoreau; B. B. Birren; J. Browne; A. Butler; A. B. Castle; N. Chiannilkulchai; C. Clee; P. J. R. Day; A. Dehejia; T. Dibling; N. Drouot; S. Duprat; C. Fizames; S. Fox; S. Gelling; L. Green; P. Harrison; R. Hocking; E. Holloway; S. Hunt; S. Keil; P. Lijnzaad; C. Louis-Dit-Sully; J. Ma; A. Mendis; J. Miller; J. Morissette; D. Muselet; H. C. Nusbaum; A. Peck; S. Rozen; D. Simon; D. K. Slonim; R. Staples; L. D. Stein; E. A. Stewart; M. A. Suchard; T. Thangarajah; N. Vega-Czarny; C. Webber; X. Wu; J. Hudson; C. Auffray; N. Nomura; J. M. Sikela; M. H. Polymeropoulous; M. R. James; E. S. Lander; T. J. Hudson; R. M. Myers; D. R. Cox; J. Weissenbach; M. S. Boguski; D. R. Bentley

Ordering of the Numerosities 1 to 9 by Monkeys, pp. 746-749
Elizabeth M. Brannon; Herbert S. Terrace

Smart Engineering in the Mid-Carboniferous: How Well Could Palaeozoic Dragonflies Fly?, pp. 749-751
R. J. Wootton; J. Kukalova-Peck; D. J. S. Newman; J. Muzón

An MTP Inhibitor that Normalizes Atherogenic Lipoprotein Levels in WHHL Rabbits, pp. 751-754
John R. Wetterau; Richard E. Gregg; Thomas W. Harrity; Cynthia Arbeeny; Michael Cap; Fergal Connolly; Ching-Hsuen Chu; Rocco J. George; David A. Gordon; Haris Jamil; Kern G. Jolibois; Lori K. Kunselman; Shih-Jung Lan; Thomas J. Maccagnan; Beverly Ricci; Mujing Yan; Douglas Young; Ying Chen; Olga M. Fryszman; Janette V. H. Logan; Christa L. Musial; Michael A. Poss; Jeffrey A. Robl; Ligaya M. Simpkins; William A. Slusarchyk; Richard Sulsky; Prakash Taunk; David R. Magnin; Joseph A. Tino; R. Michael Lawrence; John K. Dickson Jr.; Scott A. Biller

Genome Sequence of an Obligate Intracellular Pathogen of Humans: Chlamydia trachomatis, pp. 754-759
Richard S. Stephens; Sue Kalman; Claudia Lammel; Jun Fan; Rekha Marathe; L. Aravind; Wayne Mitchell; Lynn Olinger; Roman L. Tatusov; Qixun Zhao; Eugene V. Koonin; Ronald W. Davis

Attenuation of Virulence by Disruption of the Mycobacterium tuberculosis erp Gene, pp. 759-762
Francois-Xavier Berthet; Micheline Lagranderie; Pierre Gounon; Christine Laurent-Winter; Danielle Ensergueix; Pierre Chavarot; Francoise Thouron; Eddie Maranghi; Vladimir Pelicic; Denis Portnoï; Gilles Marchal; Brigitte Gicquel

Back Matter (70 pp.)

Previous Issue: New Series, Vol. 282, No. 5388, Oct. 16, 1998
Next Issue: New Series, Vol. 282, No. 5390, Oct. 30, 1998

Previous Issue: New Series, Vol. 282, No. 5389, Oct. 23, 1998
Next Issue: New Series, Vol. 282, No. 5391, Nov. 6, 1998

Front Matter (31 pp.)
Netwatch, p. 839
Jocelyn Kaiser

News

News of the Week

Seed-Sterilizing 'Terminator Technology' Sows Discord, pp. 850-851
Robert F. Service

HIV Strain Analysis Debuts in Murder Trial, pp. 851+853
Gretchen Vogel

ScienceScope, pp. 853+855
New Journals Launched to Fight Rising Prices, pp. 853-854
David Malakoff

Mutual Nonaggression Pact May Aid Ant Spread, pp. 854-855
Evelyn Strauss

Reforms at Final Stage Under New Minister, pp. 855-856
Susan Biggin

Single Gene Controls Fruit Fly Life-Span, p. 856
Elizabeth Pennisi

U.K. Government Tries to Reassure Wary Public, pp. 856-857
Nigel Williams

Panel Pulls Back Report After NIH Critique, pp. 857+859
Eliot Marshall

Opponents Criticize Iceland's Database, p. 859
Martin Enserink

News Focus

Embargoes: Good, Bad, or 'Necessary Evil'?, pp. 860-863+865-867
Eliot Marshall

Scientific Meetings Produce Clash of Agendas, pp. 867-868
Eliot Marshall

A Media Darling Thrives on Publicity, pp. 868-869
James Glanz

Random Samples, p. 871
Constance Holden

Essays on Science and Society

Inspired Choices, pp. 873-874
Paul Berg; Maxine Singer

Science's Compass

Editorial

Embracing the Embargo, p. 877
Floyd E. Bloom

Letters

Human Rights Workshop, p. 879
Irving A. Lerch

Ecological Science and the Human Predicament, p. 879
Fakhri Bazzaz; Gerardo Ceballos; Margaret Davis; Rodolfo Dirzo; Paul R. Ehrlich; Thomas Eisner; Simon Levin; John H. Lawton; Jane Lubchenco; Pamela A. Matson; Harold A. Mooney; Peter H. Raven; Joan E. Roughgarden; Jose Sarukhan; G. David Tilman; Peter Vitousek; Brian Walker; Diana H. Wall; Edward O. Wilson; George M. Woodwell

The Cerebellum: So Much More, pp. 879-880
Ralph-Axel Müller; Eric Courchesne; Greg Allen

Cosmic Chirality, pp. 880-881
Mark M. Green; Jonathan V. Selinger

Preparing Graduate Students in Biology, pp. 881-882
Andrew J. Gale; Elizabeth Marincola; Frank Solomon

Corrections and Clarifications: Dubious Benefits for Early Computer Use, p. 882
Corrections and Clarifications: The Chemistry of Water on Alumina Surfaces: Reaction Dynamics from First Principles, p. 882
Corrections and Clarifications: Monitoring Nuclear Tests, p. 882
Corrections and Clarifications: A New Look at Monogamy, p. 882

Science's Compass

Policy Forum

Nature's Subsidies to Shrimp and Salmon Farming, pp. 883-884
Rosamond L. Naylor; Rebecca J. Goldburg; Harold Mooney; Malcolm Beveridge; Jason Clay; Carl Folke; Nils Kautsky; Jane Lubchenco; Jurgenne Primavera; Meryl Williams

Books and New Media

Pieces of the Geologic Frame, Assembled, p. 885
Annals of the Former World.
John McPhee

Review author[s]: Gordon P. Eaton

Far from the Finish, p. 886
What Remains to be Discovered.
John Maddox

Review author[s]: David L. Goodstein

Perspectives

Opals in a New Light, pp. 887-888
Alfons van Blaaderen

The Artistic Side of Intermolecular Forces, pp. 888-889
Günter Reiter

The Causes of Haldane's Rule, pp. 889-891
Michael Turelli

How Cyanobacteria Count to 10, pp. 891-892
Robert Haselkorn

Just a Light Squeeze, p. 892
David Voss

Review

Long-Term Agroecosystem Experiments: Assessing Agricultural Sustainability and Global Change, pp. 893-896
Paul E. Rasmussen; Keith W. T. Goulding; James R. Brown; Peter R. Grace; H. Henry Janzen; Martin Körschens

Research

Research Articles

Carbon Structures with Three-Dimensional Periodicity at Optical Wavelengths, pp. 897-901
Anvar A. Zakhidov; Ray H. Baughman; Zafar Iqbal; Changxing Cui; Ilyas Khayrullin; Socrates O. Dantas; Jordi Marti; Victor G. Ralchenko

Force and Velocity Measured for Single Molecules of RNA Polymerase, pp. 902-907
Michelle D. Wang; Mark J. Schnitzer; Hong Yin; Robert Landick; Jeff Gelles; Steven M. Block

Reports

Strong Enhancement of Nonlinear Optical Properties Through Supramolecular Chirality, pp. 913-915
Thierry Verbiest; Sven van Elshocht; Martti Kauranen; Louis Hellemans; Johan Snauwaert; Colin Nuckolls; Thomas J. Katz; André Persoons

Spinodal Dewetting in Liquid Crystal and Liquid Metal Films, pp. 916-919
Stephan Herminghaus; Karin Jacobs; Klaus Mecke; Jörg Bischof; Andreas Fery; Mohammed Ibn-Elhaj; Stefan Schlagowski

Control of Chemical Reactions by Feedback-Optimized Phase-Shaped Femtosecond Laser Pulses, pp. 919-922
A. Assion; T. Baumert; M. Bergt; T. Brixner; B. Kiefer; V. Seyfried; M. Strehle; G. Gerber

The Effect of Alumina on the Electrical Conductivity of Silicate Perovskite, pp. 922-924
Yousheng Xu; Catherine McCammon; Brent T. Poe

Seismic Evidence for an Inner Core Transition Zone, pp. 924-927
Xiaodong Song; Don V. Helmberger

Isotopic Evidence for the Cretaceous-Tertiary Impactor and Its Type, pp. 927-929
A. Shukolyukov; G. W. Lugmair

Isotopic Mass and Lattice Constant: X-Ray Standing Wave Measurements, pp. 930-932
Alexander Kazimirov; Jörg Zegenhagen; Manuel Cardona

Spontaneous Emission Spectrum in Double Quantum Dot Devices, pp. 932-935
Toshimasa Fujisawa; Tjerk H. Oosterkamp; Wilfred G. van der Wiel; Benno W. Broer; Ramón Aguado; Seigo Tarucha; Leo P. Kouwenhoven

Heterocyst Pattern Formation Controlled by a Diffusible Peptide, pp. 935-938
Ho-Sung Yoon; James W. Golden

Binding of Hepatitis C Virus to CD81, pp. 938-941
Piero Pileri; Yasushi Uematsu; Susanna Campagnoli; Giuliano Galli; Fabiana Falugi; Roberto Petracca; Amy J. Weiner; Michael Houghton; Domenico Rosa; Guido Grandi; Sergio Abrignani

TNF-α Induction of CD44-Mediated Leukocyte Adhesion by Sulfation, pp. 941-943
Arpita Maiti; Guitta Maki; Pauline Johnson

Extended Life-Span and Stress Resistance in the Drosophila Mutant methuselah, pp. 943-946
Yi-Jyun Lin; Laurent Seroude; Seymour Benzer

Cardiovascular Failure in Mouse Embryos Deficient in VEGF Receptor-3, pp. 946-949
Daniel J. Dumont; Lotta Jussila; Jussi Taipale; Athina Lymboussaki; Tuija Mustonen; Katri Pajusola; Martin Breitman; Kari Alitalo

Loss of Intraspecific Aggression in the Success of a Widespread Invasive Social Insect, pp. 949-952
David A. Holway; Andrew V. Suarez; Ted J. Case

Haldane's Rule in Taxa Lacking a Hemizygous X, pp. 952-954
Daven C. Presgraves; H. Allen Orr

AAAS News and Notes, pp. 957-959
Tiffany Ayers

Back Matter (37 pp.)

Previous Issue: New Series, Vol. 282, No. 5389, Oct. 23, 1998
Next Issue: New Series, Vol. 282, No. 5391, Nov. 6, 1998

Previous Issue: New Series, Vol. 282, No. 5390, Oct. 30, 1998
Next Issue: New Series, Vol. 282, No. 5392, Nov. 13, 1998

Front Matter (42 pp.)
Netwatch, p. 1003
Jennifer Couzin

News

News of the Week

A Versatile Cell Line Raises Scientific Hopes, Legal Questions, pp. 1014-1015
Eliot Marshall

Life Sciences Win Bulk of Cash Bonanza, pp. 1015+1017-1018
Nigel Williams

ScienceScope, pp. 1017+1019
Low-Calorie Diets May Slow Monkey's Aging, p. 1018
Jennifer Couzin

New Leads to Brain Neuron Regeneration, pp. 1018-1019
Marcia Barinaga

Earliest Animals Old Once More?, p. 1020
Richard A. Kerr

Chemical Accessories Give DNA New Talents, pp. 1020-1021
Robert F. Service

Technique Probes Electrons' Secret Lives, pp. 1021+1023
Meher Antia

Powerful Cosmic Rays Tied to Far-Off Galaxies, p. 1023
Dennis Normile

New Law Could Open Up Lab Books, p. 1023
Jocelyn Kaiser

News Focus

Acid Rain Control: Success on the Cheap, pp. 1024-1027
Richard A. Kerr

Pollution Permits for Greenhouse Gases?, p. 1025
Jocelyn Kaiser

A Surprising Function for the PTEN Tumor Suppressor, pp. 1027+1029-1030
Karen Hopkin

Alzheimer's Treatments that Work Now, pp. 1030-1032
Marcia Barinaga

Meteor Shower Sets Off Scientific Storm, pp. 1032-1033
Andrew Lawler

Random Samples, p. 1035
Constance Holden

Essays on Science and Society

Science and Opportunity, pp. 1037-1038
Kenneth R. Manning

Science's Compass

Editorial

Publishing Controversial Research, p. 1045
Linda J. Miller; Floyd E. Bloom

Letters

Restructuring the University, p. 1047
William E. Cooper; Michael S. Gazzaniga

Human Monogamy, pp. 1047-1048
Geoffrey A. Clark

Net-Wielding Anachronisms?, pp. 1048-1049
Andrew V. Z. Brower; Darlene D. Judd; Robert J. Baker; Terry L. Yates; Holly Wichman; Jim Bull

Lectins: More Than Insecticides, p. 1049
Nathan Sharon; Irwin J. Goldstein

More Salt, Please, pp. 1049-1051
Thomas J. Moore; Lawrence J. Appel; George A. Bray; Laura P. Svetkey; William M. Vollmer; David A. McCarron

The Burning of Yellowstone-Another Perspective, p. 1051
Bill Wattenburg

Corrections and Clarifications: Organic Carbon Fluxes and Ecological Recovery from the Cretaceous-Tertiary Mass Extinction, p. 1051

Science's Compass

Policy Forum

Fossil Fuels Without CO₂ Emissions, pp. 1053-1054
E. A. Parson; D. W. Keith

Books and New Media

Simulating Nerves and Networks, p. 1055
Methods in Neuronal Modeling. From Ions to Networks.
Christof Koch; Idan Segev

Review author[s]: Michael E. Hasselmo

Comprehensive Sequence Analysis, pp. 1057-1058
OMIGA 1.1.
Oxford Molecular Group Inc.

Review author[s]: James P. Calvet

Perspectives

Metallic Reflections, pp. 1058-1059
Jeffrey Quilter

Exciting Times for PIP₂, pp. 1059-1060
Frances M. Ashcroft

New Potential for Human Embryonic Stem Cells, pp. 1061-1062
John Gearhart

Long-Term Change of Mind, pp. 1062-1063
Michael Merzenich

Neurodegeneration

[Introduction], p. 1071
Stella M. Hurtley

Viewpoint

Experimental Therapeutics of Neurodegenerative Disorders: Unmet Needs, pp. 1072-1074
Ira Shoulson

Reviews

Genetic Classification of Primary Neurodegenerative Disease, pp. 1075-1079
John Hardy; Katrina Gwinn-Hardy

Genetic Neurodegenerative Diseases: The Human Illness and Transgenic Models, pp. 1079-1083
Donald L. Price; Sangram S. Sisodia; David R. Borchelt

Research

Research Article

Photorefractive Materials for Nonvolatile Volume Holographic Data Storage, pp. 1089-1094
Lambertus Hesselink; Sergei S. Orlov; Alice Liu; Annapoorna Akella; David Lande; Ratnakar R. Neurgaonkar

Reports

Isolated and Companion Young Brown Dwarfs in the Taurus and Chamaeleon Molecular Clouds, pp. 1095-1097
Motohide Tamura; Yoichi Itoh; Yumiko Oasa; Tadashi Nakajima

Ages of Prehistoric Earthquakes Revealed by Cosmogenic Chlorine-36 in a Bedrock Fault Scarp at Hebgen Lake, pp. 1097-1099
Marek Zreda; Jay S. Noller

Detection of Centimeter-Sized Meteoroid Impact Events in Saturn's F Ring, pp. 1099-1102
Mark R. Showalter

Neptune's Partial Rings: Action of Galatea on Self-Gravitating Arc Particles, pp. 1102-1104
Heikki Salo; Jyrki Hänninen

Synthesis of Large Arrays of Well-Aligned Carbon Nanotubes on Glass, pp. 1105-1107
Z. F. Ren; Z. P. Huang; J. W. Xu; J. H. Wang; P. Bush; M. P. Siegal; P. N. Provencio

Early Central Andean Metalworking from Mina Perdida, Peru, pp. 1108-1111
Richard L. Burger; Robert B. Gordon

Nanoengineering of Inorganic and Hybrid Hollow Spheres by Colloidal Templating, pp. 1111-1114
Frank Caruso; Rachel A. Caruso; Helmuth Möhwald

Auxin-Dependent Cell Expansion Mediated by Overexpressed Auxin-Binding Protein 1, pp. 1114-1117
Alan M. Jones; Kyung-Hoam Im; Michael A. Savka; Ming-Jing Wu; Gregory DeWitt; Raymond Shillito; Andrew N. Binns

Large-Scale Sprouting of Cortical Connections After Peripheral Injury in Adult Macaque Monkeys, pp. 1117-1121
Sherre L. Florence; Hilary B. Taub; John H. Kaas

Thalamic and Brainstem Contributions to Large-Scale Plasticity of Primate Somatosensory Cortex, pp. 1121-1125
Edward G. Jones; Tim P. Pons

Chromosome 2 Sequence of the Human Malaria Parasite Plasmodium falciparum, pp. 1126-1132
Malcolm J. Gardner; Hervé Tettelin; Daniel J. Carucci; Leda M. Cummings; L. Aravind; Eugene V. Koonin; Shamira Shallom; Tanya Mason; Kelly Yu; Claire Fujii; James Pederson; Kun Shen; Junping Jing; Christopher Aston; Zhongwu Lai; David C. Schwartz; Mihaela Pertea; Steven Salzberg; Lixin Zhou; Granger G. Sutton; Rebecca Clayton; Owen White; Hamilton O. Smith; Claire M. Fraser; Mark D. Adams; J. Craig Venter; Stephen L. Hoffman

Evidence that Gene Amplification Underlies Adaptive Mutability of the Bacterial lac Operon, pp. 1133-1135
Dan I. Andersson; E. Susan Slechta; John R. Roth

Transformation of Tooth Type Induced by Inhibition of BMP Signaling, pp. 1136-1138
Abigail S. Tucker; Karen L. Matthews; Paul T. Sharpe

Membrane Phospholipid Control of Nucleotide Sensitivity of K _ATP Channels, pp. 1138-1141
S.-L. Shyng; C. G. Nichols

PIP₂ and PIP as Determinants for ATP Inhibition of K _ATP Channels, pp. 1141-1144
Thomas Baukrowitz; Uwe Schulte; Dominik Oliver; Stefan Herlitze; Tobias Krauter; Stephen J. Tucker; J. Peter Ruppersberg; Bernd Fakler

Embryonic Stem Cell Lines Derived from Human Blastocysts, pp. 1145-1147
James A. Thomson; Joseph Itskovitz-Eldor; Sander S. Shapiro; Michelle A. Waknitz; Jennifer J. Swiergiel; Vivienne S. Marshall; Jeffrey M. Jones

Back Matter (69 pp.)

Previous Issue: New Series, Vol. 282, No. 5390, Oct. 30, 1998
Next Issue: New Series, Vol. 282, No. 5392, Nov. 13, 1998

Previous Issue: New Series, Vol. 282, No. 5391, Nov. 6, 1998
Next Issue: New Series, Vol. 282, No. 5393, Nov. 20, 1998

Front Matter (28 pp.)
Netwatch, p. 1223
Jocelyn Kaiser

News

News of the Week

Democrats Match GOP in Sending a Physicist to Washington, pp. 1234-1235
David Malakoff

Understanding of Ears, Bristles Jumps a Notch, p. 1235
Gretchen Vogel

Microsoft Picks Beijing for New R&D Lab, pp. 1235+1237
Justin Wang

Canada Opens Program to Community Groups, pp. 1237-1238
Wayne Kondro

ScienceScope, pp. 1237+1239
NSF to Send College Students Into Schools, pp. 1238-1239
Jeffrey Mervis

Reaction to Stem Cells: A Tale of the Ticker, p. 1239
David Malakoff

Binaries Answer Riddle of Brown Dwarf Origins, p. 1240
Alexander Hellemans

Cold Spring Harbor to Offer Own Degrees, pp. 1240-1241
Eliot Marshall

Pasteur Recruit Resigns in Battle Over New Unit, pp. 1241+1243
Michael Balter

Genome Links Typhus Bug to Mitochondrion, p. 1243
Elizabeth Pennisi

News Focus

Training Viruses to Attack Cancers, pp. 1244-1246
Elizabeth Pennisi

Popular Interest Fuels a Dinosaur Research Boom, pp. 1246-1247
Erik Stokstad

Does Science Know the Vital Statistics of the Cosmos?, pp. 1247-1248
James Glanz

No Backing Off from the Accelerating Universe, pp. 1249+1251
James Glanz

Ocean Drilling Floats Ambitious Plans for Growth, pp. 1251-1252
Richard A. Kerr; Dennis Normile

Temperate Forests Gain Ground, p. 1253
Anne Simon Moffat

Random Samples, p. 1255
Constance Holden

Essays on Science and Society

Nobel: Always the Winners, Never the Losers, pp. 1256-1257
Elisabeth Crawford

Science's Compass

Editorial

Issues Facing the New FDA Commissioner, p. 1263
Louis Lasagna; Kenneth I. Kaitin

Letters

Fossil Discoveries in India: Continued, p. 1265
Simon Conway Morris; Sören Jensen; Nicholas J. Butterfield

California Standards, p. 1265
Steven B. Oppenheimer

Human Rights: An Issue Among Anthropologists, p. 1265
Tom Greaves

New Niches for Life Scientists, pp. 1265+1267
Elaine Caton; Jennifer Cherrier; Elizabeth Farnsworth; Scott Franklin; Beth Hufnagel; Eric Klopfer; Janet Russell; Ben Sayler

Internet Friendships, p. 1267
Philip Aspden; James E. Katz

Publishers' Honeymoon?, pp. 1267-1268
Louis M. Guenin

Apoptosis and Alzheimer's Disease, pp. 1268-1269
George Perry; Akihiko Nunomura; Paul Lucassen; Hans Lassmann; Mark A. Smith

Genetics of Alcoholism, p. 1269
Howard J. Edenberg; Tatiana Foroud; Alison Goate; John Rice; Theodore Reich; C. Robert Cloninger; John I. Nurnberger Jr.; T.-K. Li; P. M. Conneally; Jay A. Tischfield; Raymond Crowe; Victor Hesselbrock; Marc Schuckit; Bernice Porjesz; Henri Begleiter

Policy Forum

Conservation Targets in South American Temperate Forests, pp. 1271-1272
J. J. Armesto; R. Rozzi; C. Smith-Ramírez; M. T. K. Arroyo

Books and New Media

Innovative History of the Chemical Industry, pp. 1273-1274
Chemicals and Long-Term Economic Growth. Insights from the Chemical Industry.
Ashish Arora; Ralph Landau; Nathan Rosenberg

Review author[s]: Christopher Freeman

Rainforest "Crows" in Fancy Dress, p. 1274
The Birds of Paradise. Paradisaeidae.
Clifford B. Frith; Bruce M. Beehler

Review author[s]: Sherman J. Suter

Perspectives

Toughened Ceramics, p. 1275
William K. Tredway

Spinosaurs as Crocodile Mimics, pp. 1276-1277
Thomas R. Holtz Jr.

Gathering Glycine Receptors at Synapses, pp. 1277-1279
Stanley C. Froehner

A Cellular Striptease Act, pp. 1279-1280
Zena Werb; Yibing Yan

Research

Research Articles

An Essential Role for Ectodomain Shedding in Mammalian Development, pp. 1281-1284
Jacques J. Peschon; Jennifer L. Slack; Pranitha Reddy; Kim L. Stocking; Susan W. Sunnarborg; David C. Lee; William E. Russell; Beverly J. Castner; Richard S. Johnson; Jeffrey N. Fitzner; Rogely W. Boyce; Nicole Nelson; Carl J. Kozlosky; Martin F. Wolfson; Charles T. Rauch; Douglas Pat Cerretti; Raymond J. Paxton; Carl J. March; Roy A. Black

Presolar Corundum and Spinel in Ordinary Chondrites: Origins from AGB Stars and a Supernova, pp. 1284-1289
Byeon-Gak Choi; Gary R. Huss; G. J. Wasserburg; Roberto Gallino

Reports

Direct Observations of Structural Phase Transitions in Planar Crystallized Ion Plasmas, pp. 1290-1293
T. B. Mitchell; J. J. Bollinger; D. H. E. Dubin; X.-P. Huang; W. M. Itano; R. H. Baughman

Controlling Factors for the Brittle-to-Ductile Transition in Tungsten Single Crystals, pp. 1293-1295
Peter Gumbsch; Joachim Riedle; Alexander Hartmaier; Hellmut F. Fischmeister

A Tough, Thermally Conductive Silicon Carbide Composite with High Strength up to 1600°C in Air, pp. 1295-1297
Toshihiro Ishikawa; Shinji Kajii; Kenji Matsunaga; Toshihiko Hogami; Yasuhiko Kohtoku; Toshio Nagasawa

A Long-Snouted Predatory Dinosaur from Africa and the Evolution of Spinosaurids, pp. 1298-1302
Paul C. Sereno; Allison L. Beck; Didier B. Dutheil; Boubacar Gado; Hans C. E. Larsson; Gabrielle H. Lyon; Jonathan D. Marcot; Oliver W. M. Rauhut; Rudyard W. Sadleir; Christian A. Sidor; David D. Varricchio; Gregory P. Wilson; Jeffrey A. Wilson

Ultrastable Mesostructured Silica Vesicles, pp. 1302-1305
Seong Su Kim; Wenzhong Zhang; Thomas J. Pinnavaia

Large-Scale Nitrogen Oxide Plumes in the Tropopause Region and Implications for Ozone, pp. 1305-1309
Dominik Brunner; Johannes Staehelin; Dominique Jeker

Discovery of a Low-Mass Brown Dwarf Companion of the Young Nearby Star G 196-3, pp. 1309-1312
Rafael Rebolo; María R. Zapatero Osorio; Santiago Madruga; Víctor J. S. Béjar; Santiago Arribas; Javier Licandro

Requirement for MAPK Activation for Normal Mitotic Progression in Xenopus Egg Extracts, pp. 1312-1315
Thomas M. Guadagno; James E. Ferrell Jr.

Catalytic Plasticity of Fatty Acid Modification Enzymes Underlying Chemical Diversity of Plant Lipids, pp. 1315-1317
Pierre Broun; John Shanklin; Ed Whittle; Chris Somerville

Regulation of Cell Death Protease Caspase-9 by Phosphorylation, pp. 1318-1321
Michael H. Cardone; Natalie Roy; Henning R. Stennicke; Guy S. Salvesen; Thomas F. Franke; Eric Stanbridge; Steven Frisch; John C. Reed

Dual Requirement for Gephyrin in Glycine Receptor Clustering and Molybdoenzyme Activity, pp. 1321-1324
Guoping Feng; Hartmut Tintrup; Joachim Kirsch; Mia C. Nichol; Jochen Kuhse; Heinrich Betz; Joshua R. Sanes

Structure of Human Methionine Aminopeptidase-2 Complexed with Fumagillin, pp. 1324-1327
Shenping Liu; Joanne Widom; Christopher W. Kemp; Craig M. Crews; Jon Clardy

A Structural Explanation for the Recognition of Tyrosine-Based Endocytotic Signals, pp. 1327-1332
David J. Owen; Philip R. Evans

Reovirus Therapy of Tumors with Activated Ras Pathway, pp. 1332-1334
Matthew C. Coffey; James E. Strong; Peter A. Forsyth; Patrick W. K. Lee

Role for Cingulate Motor Area Cells in Voluntary Movement Selection Based on Reward, pp. 1335-1338
Keisetsu Shima; Jun Tanji

Control of Neonatal Tolerance to Tissue Antigens by Peripheral T Cell Trafficking, pp. 1338-1341
Judith Alferink; Anna Tafuri; Dietmar Vestweber; Rupert Hallmann; Günter J. Hümmerling; Bernd Arnold

Back Matter (31 pp.)

Previous Issue: New Series, Vol. 282, No. 5391, Nov. 6, 1998
Next Issue: New Series, Vol. 282, No. 5393, Nov. 20, 1998

Previous Issue: New Series, Vol. 282, No. 5392, Nov. 13, 1998
Next Issue: New Series, Vol. 282, No. 5394, Nov. 27, 1998

Front Matter (28 pp.)
Netwatch, p. 1379
Jocelyn Kaiser

News

News of the Week

Claim of Human-Cow Embryo Greeted with Skepticism, pp. 1390-1391
Eliot Marshall

Station Launch Hides Lingering Woes, pp. 1391+1393
Richard Stone

Science Gets Share of Stimulus Package, pp. 1393-1394
Dennis Normile

ScienceScope, p. 1393
India Prepares to Join U.S., World Teams, p. 1394
Pallava Bagla

Can IL-2 Smoke Out HIV Reservoirs?, pp. 1394-1395
Nigel Williams

A Possible New Partner for Telomerase, pp. 1395+1397
Elizabeth Pennisi

fMRI Provides New View of Monkey Brains, p. 1397
Marcia Barinaga

News Focus

Requiem for Life on Mars? Support for Microbes Fades, pp. 1398-1400
Richard A. Kerr

Finding Life's Limits, p. 1399
Gretchen Vogel

Buffeted Community Braces for More Change, pp. 1401+1403
Annika Nilsson; Joanna Rose

Brazil's Budget Crunch Crushes Science, pp. 1403-1404
Cássio Leite Vieira

Training a Molecular Gun on Killer E. coli, p. 1404
Richard A. Lovett

A First Step Toward Wiring Up a Quantum Computer, p. 1405
James Glanz

New Ways to Probe the Molecules of Life, pp. 1406-1407
Evelyn Strauss

Random Samples, p. 1409
Constance Holden

Essays on Science and Society

The Impact of Society on Science, pp. 1411-1412
Sydney Brenner

Science's Compass

Editorial

Animal Rights: Reaching the Public, p. 1417
P. Michael Conn; James Parker

Letters

Declining Fertility, p. 1419
Joshua Mitteldorf; Steven W. Mosher

Laboratory Safety, pp. 1419-1420
C. H. Collins; D. A. Kennedy

Patenting Genomic Technologies, pp. 1420-1421
David S. Block; Daniel J. Curran; Rebecca S. Eisenberg; Michael Heller

Corrections and Clarifications: Standards for Engineer Witnesses, p. 1421
Corrections and Clarifications: The Transcriptional Program of Sporulation in Budding Yeast, p. 1421

Science's Compass

Policy Forum

Strengthening the Biological Weapons Convention, p. 1423
Thomas P. Monath; Lance K. Gordon

Books and New Media

Terrible Lizards-Impure Science?, pp. 1424-1425
The Last Dinosaur Book. The Life and Times of a Cultural Icon.
W. J. T. Mitchell

Review author[s]: Peter Dodson

Confirming Antiquity in the Americas, pp. 1425-1426
Monte Verde. A Late Pleistocene Settlement in Chile, Vol. 2: The Archaeological Context and Interpretation.
Tom D. Dillehay

Review author[s]: Donald K. Grayson

Perspectives

The Sulfur Cycle and Atmospheric Oxygen, pp. 1426-1427
Robert A. Berner; Steven T. Petsch

Molecular Origin of Species, pp. 1428-1429
Masatoshi Nei; Jianzhi Zhang

Controlling Artificial Atoms, pp. 1429-1430
François H. Julien; Antigoni Alexandrou

Bringing the Mountain to Mohammed, pp. 1430-1431
Richard Losick; Lucy Shapiro

Review

Experimental Evolution of Parasites, pp. 1432-1435
Dieter Ebert

Tech.Sight

Hidden Models in Biopolymers, pp. 1436-1437
Mor Amitai

Techsightings, pp. 1438-1439
Robert Sikorski; Richard Peters

Archaeology: Transitions in Prehistory

[Introduction], p. 1441
Tim Appenzeller; Daniel Clery; Elizabeth Culotta

News

Why Settle Down? The Mystery of Communities, pp. 1442-1445
Michael Balter

The Slow Birth of Agriculture, pp. 1446-1450
Heather Pringle

Art: Evolution or Revolution?, pp. 1451-1454
Tim Appenzeller

No Last Word on Language Origins, pp. 1455-1458
Constance Holden

Research

Research Articles

Sulfur Isotopic Composition of Cenozoic Seawater Sulfate, pp. 1459-1462
Adina Paytan; Miriam Kastner; Douglas Campbell; Mark H. Thiemens

High-Resolution Protein Design with Backbone Freedom, pp. 1462-1467
Pehr B. Harbury; Joseph J. Plecs; Bruce Tidor; Tom Alber; Peter S. Kim

Reports

Reconstructing Past Ocean pH-Depth Profiles, pp. 1468-1471
M. R. Palmer; P. N. Pearson; S. J. Cobb

Low-Field Electron Emission from Undoped Nanostructured Diamond, pp. 1471-1473
W. Zhu; G. P. Kochanski; S. Jin

Coherent Optical Control of the Quantum State of a Single Quantum Dot, pp. 1473-1476
N. H. Bonadeo; J. Erland; D. Gammon; D. Park; D. S. Katzer; D. G. Steel

Photonic Band Gap Guidance in Optical Fibers, pp. 1476-1478
J. C. Knight; J. Broeng; T. A. Birks; P. St. J. Russell

Direct Demonstration of Milk as an Element of Archaeological Economies, pp. 1478-1481
Stephanie N. Dudd; Richard P. Evershed

Pb Isotopic Variability in Melt Inclusions from Oceanic Island Basalts, Polynesia, pp. 1481-1484
A. E. Saal; S. R. Hart; N. Shimizu; E. H. Hauri; G. D. Layne

Tankyrase, a Poly(ADP-Ribose) Polymerase at Human Telomeres, pp. 1484-1487
Susan Smith; Izabela Giriat; Anja Schmitt; Titia de Lange

Phytochromes and Cryptochromes in the Entrainment of the Arabidopsis Circadian Clock, pp. 1488-1490
David E. Somers; Paul F. Devlin; Steve A. Kay

Role of Mouse Cryptochrome Blue-Light Photoreceptor in Circadian Photoresponses, pp. 1490-1494
Randy J. Thresher; Martha Hotz Vitaterna; Yasuhide Miyamoto; Aleksey Kazantsev; David S. Hsu; Claude Petit; Christopher P. Selby; Lale Dawut; Oliver Smithies; Joseph S. Takahashi; Aziz Sancar

Induction and Evasion of Host Defenses by Type 1-Piliated Uropathogenic Escherichia coli, pp. 1494-1497
Matthew A. Mulvey; Yolanda S. Lopez-Boado; Carole L. Wilson; Robyn Roth; William C. Parks; John Heuser; Scott J. Hultgren

Requirement for p53 and p21 to Sustain G₂ Arrest After DNA Damage, pp. 1497-1501
F. Bunz; A. Dutriaux; C. Lengauer; T. Waldman; S. Zhou; J. P. Brown; J. M. Sedivy; K. W. Kinzler; B. Vogelstein

A Rapidly Evolving Homeobox at the Site of a Hybrid Sterility Gene, pp. 1501-1504
Chau-Ti Ting; Shun-Chern Tsaur; Mao-Lien Wu; Chung-I Wu

Local GABA Circuit Control of Experience-Dependent Plasticity in Developing Visual Cortex, pp. 1504-1508
Takao K. Hensch; Michela Fagiolini; Nobuko Mataga; Michael P. Stryker; Steinunn Baekkeskov; Shera F. Kash

Synaptic Segregation at the Developing Neuromuscular Junction, pp. 1508-1511
Wen-Biao Gan; Jeff W. Lichtman

The Role of Far1p in Linking the Heterotrimeric G Protein to Polarity Establishment Proteins During Yeast Mating, pp. 1511-1516
Anne-Christine Butty; Peter M. Pryciak; Linda S. Huang; Ira Herskowitz; Matthias Peter

Localization of Bacterial DNA Polymerase: Evidence for a Factory Model of Replication, pp. 1516-1519
Katherine P. Lemon; Alan D. Grossman

Back Matter (81 pp.)

Previous Issue: New Series, Vol. 282, No. 5392, Nov. 13, 1998
Next Issue: New Series, Vol. 282, No. 5394, Nov. 27, 1998

Previous Issue: New Series, Vol. 282, No. 5393, Nov. 20, 1998
Next Issue: New Series, Vol. 282, No. 5395, Dec. 4, 1998

Front Matter (41 pp.)
Netwatch, p. 1607
Jocelyn Kaiser

News

News of the Week

DNA Suggests Cultural Traits Affect Whales' Evolution, p. 1616
Gretchen Vogel

Panel Tightens Rules on Mental Disorders, p. 1617
Eliot Marshall

Hairy Mice Offer Hope for Baldness Remedy, pp. 1617+1619
Elizabeth Pennisi

Improving Gene Transfer into Livestock, pp. 1619-1620
Anne Simon Moffat

ScienceScope, pp. 1619+1621
AFMs Wield Parts for Nanoconstruction, pp. 1620-1621
Robert F. Service

Looking South to the Early Universe, pp. 1621-1622
Donald Goldsmith

High Court to Review Standard for Appeal, p. 1622
David Malakoff

Program Luring Foreign Talent Gets a Boost, p. 1623
Richard Stone

Outsmarting HIV Drug Resistance, pp. 1623+1625
Michael Balter

Experiment Stopped After Safety Concerns, p. 1625
David Malakoff

News Focus

Cuba's Billion-Dollar Biotech Gamble, pp. 1626-1628
Jocelyn Kaiser

Clock Photoreceptor Shared by Plants and Animals, pp. 1628-1630
Marcia Barinaga

HIV's Early Home and Inner Life, pp. 1630-1631
Michael Balter

From Solitaire, a Clue to the World of Prime Numbers, pp. 1631+1633
Dana Mackenzie

Random Samples, p. 1635
Constance Holden

Essays on Science and Society

Space-Where Now, and Why?, pp. 1637-1638
Carolyn Shoemaker

Science's Compass

Editorial

Priority Setting: Quixotic or Essential?, p. 1641
Floyd E. Bloom

Letters

Journal Publishing, p. 1643
Peter T. Shepherd; H. K. Lee

ACS Embargo Policy, p. 1643
Denise Graveline

Valuable Skills, pp. 1643-1644
T. J. Murphy

Environmental Health: Nickel-and-Diming It, p. 1644
Bernard Weiss

An Early Snowball Earth?, pp. 1644-1646
Gregory S. Jenkins; Christopher R. Scotese; Paul F. Hoffman; Daniel P. Schrag; Galen P. Halverson; J. Alan Kaufman

Corrections and Clarifications: NetWatch, p. 1646
Corrections and Clarifications: Rapid Identification of Subtype-Selective Agonists of the Somatostatin Receptor Through Combinatorial Chemistry, p. 1646

Science's Compass

Policy Forum

The Science and Technology-Bereft Department of State, pp. 1649-1650
Anne Keatley Solomon

Put Science and Technology Back into Foreign Policy, p. 1650
J. Thomas Ratchford

Books and New Media

Black Hole Horizons, pp. 1651-1652
Black Holes and Relativistic Stars.
Robert M. Wald

Review author[s]: Richard A. Matzner

Statistics, Fast and Easy, p. 1652
InStat 3.0.
GraphPad Software, Inc.

Review author[s]: John Wass

Perspectives

The Abominable Mystery, pp. 1653-1654
William L. Crepet

The When and Where of Floor Plate Induction, pp. 1654-1657
Jane Dodd; Thomas M. Jessell; Marysia Placzek

Go Forth and Multiply, pp. 1657-1658
Keith Burnett

No Need to Isolate Genetics, pp. 1658-1659
Michael E. Soulé; L. Scott Mills

Review

Magnetoelectronics, pp. 1660-1663
Gary A. Prinz

Research

Research Articles

In situ Measurements of Organics, Meteoritic Material, Mercury, and Other Elements in Aerosols at 5 to 19 Kilometers, pp. 1664-1669
D. M. Murphy; D. S. Thomson; M. J. Mahoney

Structure of a Covalently Trapped Catalytic Complex of HIV-1 Reverse Transcriptase: Implications for Drug Resistance, pp. 1669-1675
Huifang Huang; Rajiv Chopra; Gregory L. Verdine; Stephen C. Harrison

Reports

Anthropogenic Influence on the Autocorrelation Structure of Hemispheric- Mean Temperatures, pp. 1676-1679
T. M. L. Wigley; R. L. Smith; B. D. Santer

A Dielectric Omnidirectional Reflector, pp. 1679-1682
Yoel Fink; Joshua N. Winn; Shanhui Fan; Chiping Chen; Jurgen Michel; John D. Joannopoulos; Edwin L. Thomas

Helical Polyacetylene Synthesized with a Chiral Nematic Reaction Field, pp. 1683-1686
K. Akagi; G. Piao; S. Kaneko; K. Sakamaki; H. Shirakawa; M. Kyotani

Macroscopic Quantum Interference from Atomic Tunnel Arrays, pp. 1686-1689
B. P. Anderson; M. A. Kasevich

Viscoelastic Flow in the Lower Crust After the 1992 Landers, California, Earthquake, pp. 1689-1692
Jishu Deng; Michael Gurnis; Hiroo Kanamori; Egill Hauksson

In Search of the First Flower: A Jurassic Angiosperm, Archaefructus, from Northeast China, pp. 1692-1695
Ge Sun; David L. Dilcher; Shaoling Zheng; Zhekun Zhou

Tracking the Long-Term Decline and Recovery of an Isolated Population, pp. 1695-1698
Ronald L. Westemeier; Jeffrey D. Brawn; Scott A. Simpson; Terry L. Esker; Roger W. Jansen; Jeffery W. Walk; Eric L. Kershner; Juan L. Bouzat; Ken N. Paige

Arabidopsis NPH1: A Flavoprotein with the Properties of a Photoreceptor for Phototropism, pp. 1698-1701
John M. Christie; Philippe Reymond; Gary K. Powell; Paul Bernasconi; Andrei A. Raibekas; Emmanuel Liscum; Winslow R. Briggs

Purification and Cloning of a Protein Kinase That Phosphorylates and Activates the Polo-Like Kinase Plx1, pp. 1701-1704
Yue-Wei Qian; Eleanor Erikson; James L. Maller

Regulation of Nerve Growth Mediated by Inositol 1,4,5-Trisphosphate Receptors in Growth Cones, pp. 1705-1708
Kohtaro Takei; Ryong-Moon Shin; Takafumi Inoue; Kunio Kato; Katsuhiko Mikoshiba

Cultural Selection and Genetic Diversity in Matrilineal Whales, pp. 1708-1711
Hal Whitehead

Zebrafish hox Clusters and Vertebrate Genome Evolution, pp. 1711-1714
Angel Amores; Allan Force; Yi-Lin Yan; Lucille Joly; Chris Amemiya; Andreas Fritz; Robert K. Ho; James Langeland; Victoria Prince; Yan-Ling Wang; Monte Westerfield; Marc Ekker; John H. Postlethwait

Regulation of the Proinflammatory Effects of Fas Ligand (CD95L), pp. 1714-1717
Jian-Jun Chen; Yongnian Sun; Gary J. Nabel

Identification of Two Distinct Mechanisms of Phagocytosis Controlled by Different Rho GTPases, pp. 1717-1721
Emmanuelle Caron; Alan Hall

Control of Cyclin Ubiquitination by CDK-Regulated Binding of Hct1 to the Anaphase Promoting Complex, pp. 1721-1724
Wolfgang Zachariae; Michael Schwab; Kim Nasmyth; Wolfgang Seufert

AAAS News and Notes, p. 1742
Tiffany Ayers

Back Matter (30 pp.)

Previous Issue: New Series, Vol. 282, No. 5393, Nov. 20, 1998
Next Issue: New Series, Vol. 282, No. 5395, Dec. 4, 1998

Previous Issue: New Series, Vol. 282, No. 5394, Nov. 27, 1998
Next Issue: New Series, Vol. 282, No. 5396, Dec. 11, 1998

Front Matter (31 pp.)
NetWatch, p. 1779
Jocelyn Kaiser

News

News of the Week

On World AIDS Day, a Shadow Looms Over Southern Africa, pp. 1790-1791
Michael Balter

Songbirds Stressed in Winter Grounds, pp. 1791+1793-1794
Bernice Wuethrich

ScienceScope, pp. 1793+1795
Tabletop Laser Packs a Punch, p. 1794
Alexander Hellemans

Steadying Influence for Neurons Identified, pp. 1794-1795
Marcia Barinaga

Heat Shock Protein Mutes Genetic Changes, p. 1796
Elizabeth Pennisi

Visa Bill Creates NSF Scholarships, pp. 1796-1797
Jeffrey Mervis

Drug May Suppress the Craving for Nicotine, pp. 1797+1799
Ingrid Wickelgren

New Czar Aims to Sharpen France's Effort, p. 1799
Michael Balter

News Focus

Mixed Grades for NSF's Bold Reform of Statewide Education, pp. 1800-1805
Jeffrey Mervis

Starbirth, Gamma Blast Hint at Active Early Universe, p. 1806
James Glanz

Geologists Take a Trip to the Red Planet, pp. 1807+1809
Richard A. Kerr

Random Samples, p. 1811
Constance Holden

Essays on Science and Society

Why Must Scientists become More Ethically Sensitive Than They Used to be?, pp. 1813-1814
John Ziman

Science's Compass

Editorial

Passionate Science, p. 1821
Richard B. Gallagher; Christine Gilbert; Barbara Jasny; Andrew Lawler; Elizabeth Pennisi; Linda R. Rowan; Julia Uppenbrink

Letters

Freedom of Information Requests, p. 1823
William H. Goldwater; Michael Gough

Science, Advocacy, and Credibility, pp. 1823-1824
Warren S. Wooster

Human Cloning, pp. 1824-1825
Claire Nader; Stuart A. Newman

Lead Regulation, pp. 1825-1827
Lynn R. Goldman; Bruce P. Lanphear

Corrections and Clarifications: The Slow Birth of Agriculture, p. 1827
Corrections and Clarifications: NetWatch, p. 1827
Corrections and Clarifications: Chromosome 2 Sequence of the Human Malaria Parasite Plasmodium falciparum, p. 1827
Corrections and Clarifications: Embryonic Stem Cell Lines Derived from Human Blastocysts, p. 1827
Corrections and Clarifications: Genomics Research and Human Subjects, p. 1827
Corrections and Clarifications: Environmental Decision-Making, p. 1827

Science's Compass

Policy Forum

What can We Really Learn from TIMSS?, pp. 1830-1831
William H. Schmidt; Curtis C. McKnight

Books and New Media

Seeking Planetary Systems, p. 1832
Looking for Earths. The Race to Find New Solar Systems.
Alan Boss

Review author[s]: Jack J. Lissauer

Small Sources of Great Affliction, pp. 1832-1833
Viruses, Plagues, and History.
Michael B. A. Oldstone

Review author[s]: Robin A. Weiss

Igneous Petrology, pp. 1834-1835
Melts.
M. S. Ghiorso; R. O. Sack; M. Hirschmann; P. D. Asimow

Review author[s]: Glenn A. Gaetani

Perspectives

Just the Facts of Chromatin Transcription, pp. 1836-1837
Sam John; Jerry L. Workman

The Enigmas of Kaposi's Sarcoma, pp. 1837-1839
Robert C. Gallo

Absolute Ages Aren't Exactly, pp. 1840-1841
Paul R. Renne; Daniel B. Karner; Kenneth R. Ludwig

Mirror on the Wall: You're Omnidirectional after All?, pp. 1841-1842
Jonathan P. Dowling

Biological Hydrogen Production: Not so Elementary, pp. 1842-1843
Michael W. W. Adams; Edward I. Stiefel

Essays on Science and Society

Prize Essay, pp. 1844-1845
Hiroyuki Noji

Review

Consciousness and Complexity, pp. 1846-1851
Giulio Tononi; Gerald M. Edelman

Research

Research Articles

X-ray Crystal Structure of the Fe-Only Hydrogenase (Cpl) from Clostridium pasteurianum to 1.8 Angstrom Resolution, pp. 1853-1858
John W. Peters; William N. Lanzilotta; Brian J. Lemon; Lance C. Seefeldt

A 25,000-Year Tropical Climate History from Bolivian Ice Cores, pp. 1858-1864
L. G. Thompson; M. E. Davis; E. Mosley-Thompson; T. A. Sowers; K. A. Henderson; V. S. Zagorodnov; P.-N. Lin; V. N. Mikhalenko; R. K. Campen; J. F. Bolzan; J. Cole-Dai; B. Francou

Reports

⁵³ Mn- ⁵³ Cr Dating of Fayalite Formation in the CV3 Chondrite Mokoia: Evidence for Asteroidal Alteration, pp. 1865-1867
Ian D. Hutcheon; Alexander N. Krot; Klaus Keil; Douglas L. Phinney; Edward R. D. Scott

Magnetic Microstructure of Magnetotactic Bacteria by Electron Holography, pp. 1868-1870
Rafal E. Dunin-Borkowski; Martha R. McCartney; Richard B. Frankel; Dennis A. Bazylinski; Mihály Pósfai; Peter R. Buseck

Climate and Vegetation History of the Midcontinent from 75 to 25 ka: A Speleothem Record from Crevice Cave, Missouri, USA, pp. 1871-1874
Jeffrey A. Dorale; R. Lawrence Edwards; Emi Ito; Luis A. Gonzalez

Oxygen Isotope Exchange between Refractory Inclusion in Allende and Solar Nebula Gas, pp. 1874-1877
Hisayoshi Yurimoto; Motoo Ito; Hiroshi Nagasawa

Single-Molecule Enzymatic Dynamics, pp. 1877-1882
H. Peter Lu; Luying Xun; X. Sunney Xie

Frequency Tuning of Basilar Membrane and Auditory Nerve Fibers in the Same Cochleae, pp. 1882-1884
S. Shyamla Narayan; Andrei N. Temchin; Alberto Recio; Mario A. Ruggero

Linking Winter and Summer Events in a Migratory Bird by Using Stable-Carbon Isotopes, pp. 1884-1886
Peter P. Marra; Keith A. Hobson; Richard T. Holmes

Coupling of Mitosis to the Completion of S Phase Through Cdc34-Mediated Degradation of Wee1, pp. 1886-1889
W. Matthew Michael; John Newport

KCNQ2 and KCNQ3 Potassium Channel Subunits: Molecular Correlates of the M- Channel, pp. 1890-1893
Hong-Sheng Wang; Zongming Pan; Wenmei Shi; Barry S. Brown; Randy S. Wymore; Ira S. Cohen; Jane E. Dixon; David McKinnon

Linkage of ATM to Cell Cycle Regulation by the Chk2 Protein Kinase, pp. 1893-1897
Shuhei Matsuoka; Mingxia Huang; Stephen J. Elledge

dMi-2, a Hunchback-Interacting Protein That Functions in Polycomb Repression, pp. 1897-1900
Johannes Kehle; Dirk Beuchle; Susanne Treuheit; Bea Christen; James A. Kennison; Mariann Bienz; Jürg Müller

Requirement of RSF and FACT for Transcription of Chromatin Templates in Vitro, pp. 1900-1904
Gary LeRoy; George Orphanides; William S. Lane; Danny Reinberg

Patterning of Cortical Efferent Projections by Semaphorin-Neuropilin Interactions, pp. 1904-1906
Franck Polleux; Roman J. Giger; David D. Ginty; Alex L. Kolodkin; Anirvan Ghosh

Genetic Acceleration of AIDS Progression by a Promoter Variant of CCR5, pp. 1907-1911
Maureen P. Martin; Michael Dean; Michael W. Smith; Cheryl Winkler; Bernard Gerrard; Nelson L. Michael; Benhur Lee; Robert W. Doms; Joseph Margolick; Susan Buchbinder; James J. Goedert; Thomas R. O'Brien; Margaret W. Hilgartner; David Vlahov; Stephen J. O'Brien; Mary Carrington

Role of MEKK1 in Cell Survival and Activation of JNK and ERK Pathways Defined by Targeted Gene Disruption, pp. 1911-1914
Toshiaki Yujiri; Susan Sather; Gary R. Fanger; Gary L. Johnson

Mutation-Specific Functional Impairments in Distinct Tau Isoforms of Hereditary FTDP-17, pp. 1914-1917
Ming Hong; Victoria Zhukareva; Vanessa Vogelsberg-Ragaglia; Zbigniew Wszolek; Lee Reed; Bruce I. Miller; Dan H. Geschwind; Thomas D. Bird; Daniel McKeel; Alison Goate; John C. Morris; Kirk C. Wilhelmsen; Gerard D. Schellenberg; John Q. Trojanowski; Virginia M.-Y. Lee

Back Matter (27 pp.)

Previous Issue: New Series, Vol. 282, No. 5394, Nov. 27, 1998
Next Issue: New Series, Vol. 282, No. 5396, Dec. 11, 1998

Previous Issue: New Series, Vol. 282, No. 5395, Dec. 4, 1998
Next Issue: New Series, Vol. 282, No. 5397, Dec. 18, 1998

Front Matter (38 pp.)
NetWatch, p. 1951
Jocelyn Kaiser

News

News of the Week

Use of Stem Cells Still Legally Murky, but Hearing Offers Hope, pp. 1962-1963
Eliot Marshall

Scientific Panel Clears Breast Implants, pp. 1963+1965
Jocelyn Kaiser

Argentina, and Perhaps Its Life, Took a Hit, pp. 1965-1966
Richard A. Kerr

ScienceScope, pp. 1965+1967
Insulator's Baby Steps to Superconductivity, pp. 1966-1967
Robert F. Service

India Backs Off on Central Control, p. 1967
Pallava Bagla

Extremists Steal Minister's Spotlight, pp. 1967-1968
Robert Koenig

Forest Pact Bypasses Computer Model, pp. 1968-1969
Elizabeth Finkel

Supreme Court Gets Lesson in Enumeration, p. 1969
David Kestenbaum

Sky Survey Racks Up Record-Setting Quasars, pp. 1969+1971
James Glanz

Gates Launches $100 Million Initiative, p. 1971
Dan Ferber

News Focus

Worming Secrets from the C. elegans Genome, pp. 1972-1974
Elizabeth Pennisi

Bid for Better Beef Gives Japan a Leg Up on Cattle, pp. 1975-1976
Dennis Normile

From Army of Hackers, an Upstart Operating System, pp. 1976-1977+1979
Joseph Alper

New Minister Sets Lofty Goals, pp. 1979-1980
Richard Stone

New DOE Research Program to Boost Sagging Industry, pp. 1980-1981
David Malakoff

Random Samples, p. 1983
Constance Holden

Essays on Science and Society

Science and Religion: Lessons from History?, pp. 1985-1986
John Brooke

Science's Compass

Editorial

Staying Afloat on the Seas of Data, p. 1989
Floyd E. Bloom

Letters

Neandertals: Not So Fast, p. 1991
Milford H. Wolpoff

Solving the Acid Rain Problem, pp. 1991-1992
Gene E. Likens; Kathleen C. Weathers; Thomas J. Butler; Donald C. Buso

The Context of Molecular Data, pp. 1992-1993
Brian K. Penney

Icelandic Health Records, p. 1993
Bogi Andersen

Protein Data Bank Deposits, p. 1993
Joel L. Sussman

The Handy-Dandy Kitchen Device, pp. 1993-1994
Paul R. Abramson; Steven D. Pinkerton; Allison M. Welch; Raymond D. Semlitsch; H. Carl Gerhardt

Proprioception and the McGurk Effect, pp. 1994-1995
Jay Moody

Corrections and Clarifications: Overview and Initial Results of the Very Long Baseline Interferometry Space Observatory Programme, p. 1995

Science's Compass

Books and New Media

Edison-the View from Menlo Park, pp. 1997-1998
Edison. A Life of Invention.
Paul Israel

Review author[s]: Bettyann Holtzmann Kevles

The Long Life of a Thoughtful Teacher, p. 1998
Geons, Black Holes, and Quantum Foam. A Life in Physics.
John Archibald Wheeler; Kenneth Ford

Review author[s]: Frank Wilczek

Perspectives

A Welcome Mat for Leprosy and Lassa Fever, pp. 1999-2000
Patricia G. Spear

A New Type of Hydrogen Bond, pp. 2000-2001
Robert H. Crabtree

Jams, Waves, and Clusters, pp. 2001+2003
Dirk Helbing; Martin Treiber

Nuclear Functions Charge Ahead, pp. 2003-2004
Anita K. Hopper

C. elegans: Sequence to Biology

[Introduction], p. 2011
Jonathan Hodgkin; H. Robert Horvitz; Barbara R. Jasny; Judith Kimble

Reviews

Genome Sequence of the Nematode C. elegans: A Platform for Investigating Biology, pp. 2012-2018
The C. elegans Sequencing Consortium

Zinc Fingers in Caenorhabditis elegans: Finding Families and Probing Pathways, pp. 2018-2022
Neil D. Clarke; Jeremy M. Berg

Comparison of the Complete Protein Sets of Worm and Yeast: Orthology and Divergence, pp. 2022-2028
Stephen A. Chervitz; L. Aravind; Gavin Sherlock; Catherine A. Ball; Eugene V. Koonin; Selina S. Dwight; Midori A. Harris; Kara Dolinski; Scott Mohr; Temple Smith; Shuai Weng; J. Michael Cherry; David Botstein

Neurobiology of the Caenorhabditis elegans Genome, pp. 2028-2033
Cornelia I. Bargmann

The Taxonomy of Developmental Control in Caenorhabditis elegans, pp. 2033-2041
Gary Ruvkun; Oliver Hobert

Caenorhabditis elegans is a Nematode, pp. 2041-2046
Mark Blaxter

Research

Research Article

Observations of the North Polar Region of Mars from the Mars Orbiter Laser Altimeter, pp. 2053-2060
Maria T. Zuber; David E. Smith; Sean C. Solomon; James B. Abshire; Robert S. Afzal; Oded Aharonson; Kathryn Fishbaugh; Peter G. Ford; Herbert V. Frey; James B. Garvin; James W. Head; Anton B. Ivanov; Catherine L. Johnson; Duane O. Muhleman; Gregory A. Neumann; Gordon H. Pettengill; Roger J. Phillips; Xiaoli Sun; H. Jay Zwally; W. Bruce Banerdt; Thomas C. Duxbury

Reports

A 3.3-Ma Impact in Argentina and Possible Consequences, pp. 2061-2063
P. H. Schultz; M. Zarate; W. Hames; C. Camilión; J. King

The Dusty Atmosphere of the Brown Dwarf Gliese 229B, pp. 2063-2067
Caitlin A. Griffith; Roger V. Yelle; Mark S. Marley

Photoemission Evidence for a Remnant Fermi Surface and a d-Wave-Like Dispersion in Insulating Ca₂CuO₂Cl₂, pp. 2067-2072
F. Ronning; C. Kim; D. L. Feng; D. S. Marshall; A. G. Loeser; L. L. Miller; J. N. Eckstein; I. Bozovic; Z.-X. Shen

Promotion of Trophoblast Stem Cell Proliferation by FGF4, pp. 2072-2075
Satoshi Tanaka; Tilo Kunath; Anna-Katerina Hadjantonakis; Andras Nagy; Janet Rossant

Role of α-Dystroglycan as a Schwann Cell Receptor for Mycobacterium leprae, pp. 2076-2079
Anura Rambukkana; Hiroki Yamada; George Zanazzi; Todd Mathus; James L. Salzer; Peter D. Yurchenco; Kevin P. Campbell; Vincent A. Fischetti

Identification of α-Dystroglycan as a Receptor for Lymphocytic Choriomeningitis Virus and Lassa Fever Virus, pp. 2079-2081
Wei Cao; Michael D. Henry; Persephone Borrow; Hiroki Yamada; John H. Elder; Eugene V. Ravkov; Stuart T. Nichol; Richard W. Compans; Kevin P. Campbell; Michael B. A. Oldstone

Proofreading and Aminoacylation of tRNAs before Export from the Nucleus, pp. 2082-2085
Elsebet Lund; James E. Dahlberg

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene, pp. 2085-2088
Alexander Poltorak; Xiaolong He; Irina Smirnova; Mu-Ya Liu; Christophe Van Huffel; Xin Du; Dale Birdwell; Erica Alejos; Maria Silva; Chris Galanos; Marina Freudenberg; Paola Ricciardi-Castagnoli; Betsy Layton; Bruce Beutler

Exploiting the Basis of Proline Recognition by SH3 and WW Domains: Design of N-Substituted Inhibitors, pp. 2088-2092
Jack T. Nguyen; Christoph W. Turck; Fred E. Cohen; Ronald N. Zuckerman; Wendell A. Lim

Defective T Cell Differentiation in the Absence of Jnk1, pp. 2092-2095
Chen Dong; Derek D. Yang; Mark Wysk; Alan J. Whitmarsh; Roger J. Davis; Richard A. Flavell

Eight Calves Cloned from Somatic Cells of a Single Adult, pp. 2095-2098
Yoko Kato; Tetsuya Tani; Yusuke Sotomaru; Kazuo Kurokawa; Jun-ya Kato; Hiroshi Doguchi; Hiroshi Yasue; Yukio Tsunoda

Elevating the Vitamin E Content of Plants Through Metabolic Engineering, pp. 2098-2100
David Shintani; Dean DellaPenna

Back Matter (40 pp.)

Previous Issue: New Series, Vol. 282, No. 5395, Dec. 4, 1998
Next Issue: New Series, Vol. 282, No. 5397, Dec. 18, 1998

Previous Issue: New Series, Vol. 282, No. 5396, Dec. 11, 1998
Next Issue: New Series, Vol. 283, No. 5398, Jan. 1, 1999

Front Matter (33 pp.)
NetWatch, p. 2147
Jocelyn Kaiser

Breakthrough of the Year, pp. 2156-2161

News

News of the Week

CNRS Researchers Take Up the Fight Against Allegre's Reforms, pp. 2162-2163
Michael Balter

Birds May Refine Their Songs While Sleeping, pp. 2163+2165
Marcia Barinaga

Panel Proposes Tighter Rules for Tissue Studies, pp. 2165-2166
Eliot Marshall

ScienceScope, pp. 2165+2167
Powerful Pulses Color Thomson Scattering, pp. 2166-2167
Alexander Hellemans

Britain Urged to Expand Embryo Studies, pp. 2167-2168
Eliot Marshall

Interleukin-13's Key Role in Asthma Shown, p. 2168
Gretchen Vogel

Papers Posit Grave Impact of Trawling, pp. 2168-2169
David Malakoff

A Second Hint of Symmetry Violation, pp. 2169+2171
James Glanz

15 New Projects Bolster Basic Research, p. 2171
Xiong Lei

News Focus

Coming to Grips with the Golgi, pp. 2172-2174
Carol Featherstone

Beefed-Up NIH Center Probes Unconventional Therapies, pp. 2175-2176
Jennifer Couzin

Toting Up the Early Harvest of Transgenic Plants, pp. 2176-2178
Anne Simon Moffat

Making Devices Smaller, Brighter, and More Bendy, pp. 2179-2180
Robert F. Service

Gravity Measurements Close in on Big G, pp. 2180-2181
David Kestenbaum

Random Samples, p. 2183
Constance Holden

Essays on Science and Society

Learning from the Chimpanzees: A Message Humans Can Understand, pp. 2184-2185
Jane Goodall

Association Affairs

The AAAS Celebrates Its 150th, pp. 2186-2190
Mildred S. Dresselhaus

Science's Compass

Editorial

Breakthroughs 1998, p. 2193
Floyd E. Bloom

Letters

Biological Weapons Control, p. 2194
Johannes Rath; Bernhard Jank; Otto Doblhoff-Dier; Thomas P. Monath; Lance K. Gordon

Managing Alzheimer's Patients, pp. 2194-2195
Robert P. Friedland; Barbara Krasner

AIDS Vaccine Trials in Chimpanzees, pp. 2195-2196
Alfred M. Prince; Linda Andrus; Norman L. Letvin

Hydrogen Chemistry of Basalt Aquifers, p. 2196
Allan Treiman; Annika Wallendahl; Derek R. Lovley; Robert T. Anderson; Francis H. Chapelle

Corrections and Clarifications: A Glimpse of the Holy Grail?, p. 2196

Science's Compass

Books and New Media

Expressing Freudian Influences, pp. 2197-2198
Sigmund Freud: Conflict and Culture.
Michael S. Roth

Freud: Conflict and Culture. Essays on His Life, Work, and Legacy.
Michael S. Roth

Review author[s]: Julio Licinio

Statistical Buddy, p. 2198
Data Desk 6.0. Data Description Inc.

Review author[s]: Brian R. Shmaefsky

Perspectives

Tropical Paradise at the Cretaceous Poles?, pp. 2199-2200
Brian T. Huber

Auxin Transport: Down and Out and Up Again, pp. 2201-2202
Alan M. Jones

Pumping Iron Through Cell Membranes, pp. 2202-2203
Volkmar Braun

Review

Carbon in the Universe, pp. 2204-2210
Th. Henning; F. Salama

Tech.Sight

Cold Gas Traps for Ice Particle Formation, pp. 2211-2212
S. Bauerecker; B. Neidhart

Techsighting, pp. 2213-2214
Robert Sikorski; Richard Peters

Research

Research Articles

Siderophore-Mediated Iron Transport: Crystal Structure of FhuA with Bound Lipopolysaccharide, pp. 2215-2220
Andrew D. Ferguson; Eckhard Hofmann; James W. Coulton; Kay Diederichs; Wolfram Welte

Structure of the MscL Homolog from Mycobacterium tuberculosis: A Gated Mechanosensitive Ion Channel, pp. 2220-2226
Geoffrey Chang; Robert H. Spencer; Allen T. Lee; Margaret T. Barclay; Douglas C. Rees

Regulation of Polar Auxin Transport by AtPIN1 in Arabidopsis Vascular Tissue, pp. 2226-2230
Leo Gälweiler; Changhui Guan; Andreas Müller; Ellen Wisman; Kurt Mendgen; Alexander Yephremov; Klaus Palme

A Free-Fall Determination of the Newtonian Constant of Gravity, pp. 2230-2234
Joshua P. Schwarz; Douglas S. Robertson; Timothy M. Niebauer; James E. Faller

Reports

Abrupt Climate Oscillations During the Last Deglaciation in Central North America, pp. 2235-2238
Zicheng Yu; Ulrich Eicher

The Percolation Phase Transition in Sea Ice, pp. 2238-2241
K. M. Golden; S. F. Ackley; V. I. Lytle

Evidence for Extreme Climatic Warmth from Late Cretaceous Arctic Vertebrates, pp. 2241-2244
J. A. Tarduno; D. B. Brinkman; P. R. Renne; R. D. Cottrell; H. Scher; P. Castillo

Hierarchically Ordered Oxides, pp. 2244-2246
Peidong Yang; Tao Deng; Dongyuan Zhao; Pingyun Feng; David Pine; Bradley F. Chmelka; George M. Whitesides; Galen D. Stucky

Atomic Contributions to the Optical Rotation Angle as a Quantitative Probe of Molecular Chirality, pp. 2247-2250
Rama K. Kondru; Peter Wipf; David N. Beratan

Behavioral State Modulation of Auditory Activity in a Vocal Motor System, pp. 2250-2254
Amish S. Dave; Albert C. Yu; Daniel Margoliash

Microscale Nutrient Patches in Planktonic Habitats Shown by Chemotactic Bacteria, pp. 2254-2256
Nicholas Blackburn; Tom Fenchel; Jim Mitchell

Prevention of Population Cycles by Parasite Removal, pp. 2256-2258
Peter J. Hudson; Andy P. Dobson; Dave Newborn

Interleukin-13: Central Mediator of Allergic Asthma, pp. 2258-2261
Marsha Wills-Karp; Jackie Luyimbazi; Xueying Xu; Brian Schofield; Tamlyn Y. Neben; Christopher L. Karp; Debra D. Donaldson

Requirement for IL-13 Independently of IL-4 in Experimental Asthma, pp. 2261-2263
Gabriele Grunig; Martha Warnock; Adil E. Wakil; Rajeev Venkayya; Frank Brombacher; Donna M. Rennick; Dean Sheppard; Markus Mohrs; Debra D. Donaldson; Richard M. Locksley; David B. Corry

Molecular Basis of T Cell Inactivation by CTLA-4, pp. 2263-2266
Kyung-Mi Lee; Ellen Chuang; Matthew Griffin; Roli Khattri; David K. Hong; Weiguo Zhang; David Straus; Lawrence E. Samelson; Craig B. Thompson; Jeffrey A. Bluestone

A Receptor/Cytoskeletal Movement Triggered by Costimulation During T Cell Activation, pp. 2266-2269
Christoph Wülfing; Mark M. Davis

p53-Independent Role of MDM2 in TGF-β1 Resistance, pp. 2270-2272
Peiqing Sun; Ping Dong; Kang Dai; Gregory J. Hannon; David Beach

Regulation of Cocaine Reward by CREB, pp. 2272-2275
William A. Carlezon Jr.; Johannes Thome; Valerie G. Olson; Sarah B. Lane-Ladd; Edward S. Brodkin; Noboru Hiroi; Ronald S. Duman; Rachael L. Neve; Eric J. Nestler

A Family of cAMP-Binding Proteins That Directly Activate Rap1, pp. 2275-2279
Hiroaki Kawasaki; Gregory M. Springett; Naoki Mochizuki; Shinichiro Toki; Mie Nakaya; Michiyuki Matsuda; David E. Housman; Ann M. Graybiel

AAAS News and Notes, pp. 2294-2295
Tiffany Ayers

Back Matter (41 pp.)

Previous Issue: New Series, Vol. 282, No. 5396, Dec. 11, 1998
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