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Science, New Series, Vol. 274, No. 5287, Genome Issue, Oct. 25, 1996


Previous Issue: New Series, Vol. 274, No. 5286, Oct. 18, 1996
Next Issue: New Series, Vol. 274, No. 5288, Nov. 1, 1996


Front Matter (51 pp.)
Editorial: Landing on the Genome, p. 479
Jean Weissenbach


Letters
Tritium Production, pp. 481-483
W. B. Herrmannsfeldt; Gustave K. Kohn; John C. Browne; Darrell R. Fisher; Kenneth D. Dobbin; Alan R. Waltar; Charles W. Lindenmeier; Peter J. Price
Science for Nonmajors...and Majors, pp. 483-484
Robert L. Lichter
Hippocampal Neurodegeneration in Aging, pp. 484-485
Michela Gallagher; Philip W. Landfield; Bruce McEwen; Michael J. Meaney; Peter R. Rapp; Robert Sapolsky; Mark J. West
Earth's Carrying Capacity, p. 485
Paul E. Waggoner


Corrections and Clarifications: Universities step up to the challenge, p. 485
Corrections and Clarifications: The Secreted Product of Xenopus Gene Lunatic Fringe, a Vertebrate Signaling Molecule, p. 485
ScienceScope, p. 487
Jocelyn Kaiser


News and Comment
The Genome Program's Conscience, pp. 488-490
Eliot Marshall
Research 'Summit' Ponders Health Funding Shortfall, pp. 491-492
Jon Cohen
A 'Reforestation Plan' for Biomedical Research, p. 492
Wayne Kondro
Wayward Grizzlies Spark Debate, p. 493
Bernice Wuethrich
Livermore Settles Audit for $2.7 Million, pp. 493-494
Andrew Lawler
Treaty Draft Raises Scientific Hackles, p. 494
Andrew Lawler
NASA Slices Biology Program on Station, p. 495
Andrew Lawler
Plantes Galore, But No Place Like Home, p. 495
Govert Schilling


Research News
Coming to Grips With Genes and Risk, pp. 496-498
Patricia Kahn
Ice Rhythms: Core Reveals a Plethora of Climate Cycles, pp. 499-500
Richard A. Kerr
Mutant Mice and Worms Help Solve Mysteries of Olfaction, pp. 500-501
Marcia Barinaga
Investigators Detail HIV's Fatal Handshake, p. 502
Jon Cohen
Linker Histones, DNA's Protein Custodians, Gain New Respect, pp. 503-504
Elizabeth Pennisi
To Send Data, Physicists Resort to Quantum Voodoo, pp. 504-505
Gary Taubes


Random Samples, p. 507
Constance Holden


Book Reviews
Conditions of Science, p. 521
Science and Dissent in Post-Mao China. The Politics of Knowledge.
H. Lyman Miller
Review author[s]: Merle Goldman
Brain Structures, pp. 521-522
Comparative Vertebrate Neuroanatomy. Evolution and Adaptation.
Ann B. Butler; William Hoods
Review author[s]: Edward G. Jones
Papers in Physics, pp. 522-523
Particle Physics. One Hundred Years of Discoveries. An Annotated Chronological Bibliography.
V. V. Exhela
Review author[s]: Paul Forman


Perspectives
Duality in Perspective, pp. 524-525
S. M. Girvin
Animal Origins, pp. 525-526
Geerat J. Vermeij
Out, Damned CLIP! Out, I Say!, pp. 526-527
Paul A. Roche
One plus one is not two, p. 527
David Voss


Genomes


Policy Forums
Genomic Sequence Information Should Be Released Immediately and Freely in the Public Domain, pp. 533-534
David R. Bentley
Should Non-Peer-Reviewed Raw DNA Sequence Data Release be Forced on the Scientific Community?, pp. 534-536
Mark D. Adams; J. Craig Venter
The New Genomics: Global Views of Biology, pp. 536-539
Eric S. Lander

A Gene Map of the Human Genome, pp. 540-546
G. D. Schuler; M. S. Boguski; E. A. Stewart; L. D. Stein; G. Gyapay; K. Rice; R. E. White; P. Rodriguez-Tomé; A. Aggarwal; E. Bajorek; S. Bentolila; B. B. Birren; A. Butler; A. B. Castle; N. Chiannilkulchai; A. Chu; C. Clee; S. Cowles; P. J. R. Day; T. Dibling; N. Drouot; I. Dunham; S. Duprat; C. East; C. Edwards; J.-B. Fan; N. Fang; C. Fizames; C. Garrett; L. Green; D. Hadley; M. Harris; P. Harrison; S. Brady; A. Hicks; E. Holloway; L. Hui; S. Hussain; C. Louis-Dit-Sully; J. Ma; A. MacGilvery; C. Mader; A. Maratukulam; T. C. Matise; K. B. McKusick; J. Morissette; A. Mungall; D. Muselet; H. C. Nusbaum; D. C. Page; A. Peck; S. Perkins; M. Piercy; F. Qin; J. Quackenbush; S. Ranby; T. Reif; S. Rozen; C. Sanders; X. She; J. Silva; D. K. Slonim; C. Soderlund; W.-L. Sun; P. Tabar; T. Thangarajah; N. Vega-Czarny; D. Vollrath; S. Voyticky; T. Wilmer; X. Wu; M. D. Adams; C. Aufiray; N. A. R. Walter; R. Brandon; A. Dehejia; P. N. Goodfellow; R. Houlgatte; J. R. Hudson Jr.; S. E. Ide; K. R. Iorio; W. Y. Lee; N. Seki; T. Nagase; K. Ishikawa; N. Nomura; C. Phillips; M. H. Polymeropoulos; M. Sandusky; K. Schmitt; R. Berry; K. Swanson; R. Torres; J. C. Venter; J. M. Sikela; J. S. Beckmann; J. Weissenbach; R. M. Myers; D. R. Cox; M. R. James; D. Bentley; P. Deloukas; E. S. Lander; T. J. Hudson
Life with 6000 Genes, pp. 546+563-567
A. Gofieau; B. G. Barrell; H. Bussey; R. W. Davis; B. Dujon; H. Feldmann; F. Galibert; J. D. Hoheisel; C. Jacq; M. Johnston; E. J. Louis; H. W. Mewes; Y. Murakami; P. Philippsen; H. Tettelin; S. G. Oliver
Genome Maps 7: The Human Transcript Map, pp. 551-562
Barbara R. Jasny; G. D. Schuler; M. S. Boguski; T. J. Hudson; L. Hui; J. Ma; A. B. Castle; X. Wu; J. Silva; H. C. Nusbaum; B. B. Birren; D. K. Slonim; S. Rozen; L. D. Stein; D. Page; E. S. Lander; E. A. Stewart; A. Aggarwal; E. Bajorek; S. Brady; A. Chu; N. Fang; D. Hadley; M. Harris; S. Hussain; A. Maratukulam; S. Perkins; M. Piercy; F. Qin; T. Reif; C. Sanders; X. She; W. L. Sun; P. Tabar; S. Voyticky; C. Mader; K. B. McKusick; J. B. Fan; S. Cowles; J. Quackenbush; D. Vollrath; R. M. Myers; D. R. Cox; A. Butler; C. Clee; T. Dibling; C. East; C. Edwards; C. Garrett; L. Green; P. Harrison; A. Hicks; E. Holloway; S. Ranby; A. MacGilvery; A. Mungall; A. Peck; T. Wilmer; C. Soderlund; K. Rice; I. Dunham; D. Bentley; P. Deloukas; G. Gyapay; N. Chiannilkulchai; C. Fizames; S. Bentolila; S. Duprat; N. Vega-Czarny; D. Muselet; N. Drouot; J. Morissette; J. Beckmann; J. Weissenbach.; M. R. James; R. E. White; T. Thangarajah; C. Louis-Dit-Sully; P. J. R. Day; P. N. Goodfellow; K. Schmitt; N. A. R. Walter; R. Berry; K. R. Iorio; J. M. Sikela; M. H. Polymeropoulos; R. Torres; S. S. E. Ide; A. Dehejia; R. Houlgatte; C. Auffray; M. D. Adams; C. Phillips; R. Brandon; M. Sandusky; J. C. Venter; N. Seki; T. Nagase; K. Ishikawa; N. Nomura; P. Rodriguez-Tome; T. C. Matise; W. Y. Lee; K. A. Swanson; J. R. Hudson Jr.


Research Article
Molecular Evidence for Deep Precambrian Divergences Among Metazoan Phyla, pp. 568-573
Gregory A. Wray; Jeffrey S. Levinton; Leo H. Shapiro


Reports
Far-Infrared Emission Spectra of Selected Gas-Phase PAHs: Spectroscopic Fingerprints, pp. 582-583
K. Zhang; B. Guo; P. Colarusso; P. F. Bernath
Optical Control of Photogenerated Ion Pair Lifetimes: An Approach to a Molecular Switch, pp. 584-587
Martin P. Debreczeny; Walter A. Svec; Michael R. Wasielewski
Interlayer Tunneling Models of Cuprate Superconductivity: Implication of a Recent Experiment, pp. 587-589
A. J. Leggett
Evidence for Charge-Flux Duality near the Quantum Hall Liquid-to-Insulator Transition, pp. 589-592
D. Shahar; D. C. Tsui; M. Shayegan; E. Shimshoni; S. L. Sondhi
Seismic Evidence for a Low-Velocity Zone in the Upper Crust Beneath Mount Vesuvius, pp. 592-594
A. Zollo; P. Gasparini; J. Virieux; H. le Meur; G. de Natale; G. Biella; E. Boschi; P. Capuano; R. de Franco; P. dell'Aversna; R. de Matteis; I. Guerra; G. Iannaccone; L. Mirabile; G. Vilardo
Presynaptic Calcium Current Modulation by a Metabotropic Glutamate Receptor, pp. 594-597
Tomoyuki Takahashi; Ian D. Forsythe; Tetsuhiro Tsujimoto; Margaret Barnes-Davies; Kayoko Onodera
Identification of an Asymmetrically Localized Sensor Histidine Kinase Responsible for Temporally and Spatially Regulated Transcription, pp. 597-601
James A. Wingrove; James W. Gober
Evidence for Cell-Surface Association Between Fusin and the CD4-gp 120 Complex in Human Cell Lines, pp. 602-605
Cheryl K. Lapham; Jun Ouyang; Bhaskar Chandrasekhar; Nga Y. Nguyen; Dimiter S. Dimitrov; Hana Golding
Tat-SF1: Cofactor for Stimulation of Transcirptional Elongation by HIV-1 Tat, pp. 605-610
Qiang Zhou; Phillip A. Sharp
Accessing Genetic Information with High-Density DNA Arrays, pp. 610-614
Mark Chee; Robert Yang; Earl Hubbell; Anthony Berno; Xiaohua C. Huang; David Stern; Jim Winkler; David J. Lockhart; Macdonald S. Morris; Stephen P. A. Fodor
An Asymmetric Model for the Nucleosome: A Binding Site for Linker Histones Inside the DNA Gyres, pp. 614-617
Dmitry Pruss; Blaine Bartholomew; Jim Persinger; Jeffrey Hayes; Gina Arents; Evangelos N. Moudrianakis; Alan P. Wolffe
Enhanced Dissociation of HLA-DR-Bound Peptides in the Presence of HLA-DM, pp. 618-620
Dominique A. Weber; Brian D. Evavold; Peter E. Jensen
Genetic Discrimination: Perspectives of Consumers, pp. 621-624
E. Virginia Lapham; Chahira Kozma; Joan O. Weiss
Kap 104p: A Karyopherin Involved in the Nuclear Transport of Messenger RNA Binding Proteins, pp. 624-627
John D. Aitchison; Gunter Blobel; Michael P. Rout


Technical Comments
Optical Triggers of Protein Folding, pp. 628-629
Chi-Kin Chan; James Hofrichter; William A. Eaton; Jay R. Winkler; Harry B. Gray
Complementary DNA for 12-Kilodalton B Cell Growth Factor: Misassigned, pp. 629-631
Panu E. Kovanen; Leena Harju; Tuomo Timonen; Ewa Ziȩtkiewicz; Wojciech Makałowski; Grant Mitchell; Damian Labuda; Surendra Sharma; Shashi Mehta; John Morgan; Abby Maizel


AAAS News & Notes, p. 637
Diana Parsell

Back Matter (51 pp.)

Previous Issue: New Series, Vol. 274, No. 5286, Oct. 18, 1996
Next Issue: New Series, Vol. 274, No. 5288, Nov. 1, 1996



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