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Science, New Series, Vol. 258, No. 5081, Oct. 16, 1992


Previous Issue: New Series, Vol. 258, No. 5080, Oct. 9, 1992
Next Issue: New Series, Vol. 258, No. 5082, Oct. 23, 1992


Front Matter (20 pp.)
Editorial: Concerning the Future of the NSF, p. 379
F. Albert Cotton


Letters
Understanding Chemistry, p. 381
Herbert D. Thier
Use of Animal Drugs, p. 381
Gerald B. Guest
Hydrogen Bonding, pp. 381-382
Bruce C. Faust; G. A. Blake
Carbon Budget Estimates, pp. 382-383
Edward B. Rastetter; R. A. Houghton; Pekka E. Kauppi; Kari Mielikäinen; Kullervo Kuusela


Corrections and Clarifications: DNA Fingerprinting: Academy Reports, p. 383


Policy Forum
Science Policy: The Candidates' Response, pp. 384-385+492-493


ScienceScope, p. 387
Richard Stone


News and Comment
Searching for Markers on the AIDS Trail, pp. 388-390
Jon Cohen
Dustup in the Bone Pile: Academics V. Collectors, pp. 391-392
Virginia Morell
Peering Through a Lens, Sharply, p. 393
Faye Flam
Who's Who Among Science Advisers, p. 393
David P. Hamilton
Study Casts Doubt on Hiroshima Data, p. 394
Eliot Marshall
NASA Urged to Pump Up Its First 'A', pp. 394-395
Ivan Amato
Pinatubo Fails to Deepen the Ozone Hole, p. 395
Richard A. Kerr


Random Samples, pp. 396-397
Constance Holden


Research News
Mortality: Overturning Received Wisdom, pp. 398-399
Marcia Barinaga
Chemists Cluster in Chicago to Confer on Cagey Compounds, pp. 400-401
Anne Simon Moffat
An Everyman's Free-Electron Laser?, p. 401
Ivan Amato
Dictyostelium Researchers Expect Gene Bonanza, pp. 402-403
Jean Marx
Earth Gains a Retinue of Mini-Asteroids, p. 403
Richard A. Kerr


Perspective
New Ideas for Guiding the Evolution of a Quantum System, pp. 412-413
Stuart A. Rice


Macroscopic Quantum Effects in Nanometer-Scale Magnets, pp. 414-421
David D. Awschalom; David P. DiVincenzo; Joseph F. Smyth

The Age and Size of the Universe, pp. 421-424
Sidney van den Bergh

E2F: A Link Between the Rb Tumor Suppressor Protein and Viral Oncoproteins, pp. 424-429
Joseph R. Nevins


Research Articles
An Instability in Neutron Stars at Birth, pp. 430-434
Adam Burrows; Bruce A. Fryxell
Atomic Structure of the DNA Repair [4Fe-4S] Enzyme Endonuclease III, pp. 434-440
Che-Fu Kuo; Duncan E. McRee; Cindy L. Fisher; Suzanne F. O'Handley; Richard P. Cunningham; John A. Tainer


Reports
Polymerization-Induced Epitaxy: Scanning Tunneling Microscopy of a Hydrogen-Bonded Sheet of Polyamide on Graphite, pp. 441-443
Masahito Sano; Darryl Y. Sasaki; Toyoki Kunitake
Small-Angle Synchrotron X-ray Scattering Reveals Distinct Shape Changes of the Myosin Head During Hydrolysis of ATP, pp. 443-447
Katsuzo Wakabayashi; Makio Tokunaga; Izumi Kohno; Yasunobu Sugimoto; Toshiaki Hamanaka; Yasunori Takezawa; Takeyuki Wakabayashi; Yoshiyuki Amemiya
Neural Computing in Cancer Drug Development: Predicting Mechanism of Action, pp. 447-451
John N. Weinstein; Kurt W. Kohn; Michael R. Grever; Vellarkad N. Viswanadhan; Lawrence V. Rubinstein; Anne P. Monks; Dominic A. Scudiero; Lester Welch; Antonis D. Koutsoukos; August J. Chiausa; Kenneth D. Paull
Age and Duration of Weathering by 40 K- 40 Ar and 40 Ar/ 39 Ar Analysis of Potassium-Manganese Oxides, pp. 451-455
Paulo M. Vasconcelos; Tim A. Becker; Paul R. Renne; George H. Brimhall
Some Anthropological Aspects of the Prehistoric Tyrolean Ice Man, pp. 455-457
Horst Seidler; Wolfram Bernhard; Maria Teschler-Nicola; Werner Platzer; Dieter zur Nedden; Rainer Henn; Andreas Oberhauser; Thorstein Sjøvold
Slowing of Mortality Rates at Older Ages in Large Medfly Cohorts, pp. 457-461
James R. Carey; Pablo Liedo; Dina Orozco; James W. Vaupel
Demography of Genotypes: Failure of the Limited Life-Span Paradigm in Drosophila melanogaster, pp. 461-463
James W. Curtsinger; Hidenori H. Fukui; David R. Townsend; James W. Vaupel
Absorption Spectra of the Hybrid Pigments Responsible for Anomalous Color Vision, pp. 464-466
Shannath L. Merbs; Jeremy Nathans
Isomerase and Chaperone Activity of Prolyl Isomerase in the Folding of Carbonic Anhydrase, pp. 466-468
Per-Ola Freskgård; Nils Bergenhem; Bengt-Harald Jonsson; Magdalena Svensson; Uno Carlsson
Spontaneous Hypercholesterolemia and Arterial Lesions in Mice Lacking Apolipoprotein E, pp. 468-471
Sunny H. Zhang; Robert L. Reddick; Jorge A. Piedrahita; Nobuyo Maeda
Formation of a Gated Channel by a Ligand-Specific Transport Protein in the Bacterial Outer Membrane, pp. 471-475
Jeanette M. Rutz; Jun Liu; Jeri Ann Lyons; Joanne Goranson; Sandra K. Armstrong; Mark A. McIntosh; Jimmy B. Feix; Phillip E. Klebba
DNA Polymerase β and DNA Synthesis in Xenopus Oocytes and in a Nuclear Extract, pp. 475-478
Timothy M. Jenkins; Jitendra K. Saxena; Amalendra Kumar; Samuel H. Wilson; Eric J. Ackerman
The Primary Structure of MEK, a Protein Kinase That Phosphorylates the ERK Gene Product, pp. 478-480
Craig M. Crews; Alessandro Alessandrini; Raymond L. Erikson
Removal of Nonhomologous DNA Ends in Double-Strand Break Recombination: The Role of the Yeast Ultraviolet Repair Gene RAD1, pp. 480-484
Jacqueline Fishman-Lobell; James E. Haber
Interaction of the Immunosuppressant Deoxyspergualin with a Member of the Hsp70 Family of Heat Shock Proteins, pp. 484-486
Steven G. Nadler; Mark A. Tepper; Bernice Schacter; Charles E. Mazzucco


Book Reviews
Inside Creationism, pp. 487-488
The Creationists. The Evolution of Scientific Creationism.
Ronald L. Numbers
Review author[s]: J. David Hoeveler, Jr.
Stakeholders in Misfortune, pp. 489-490
The Disability Business. Rehabilitation in America.
Gary L. Albrecht
Review author[s]: Edward D. Berkowitz
A Sometime Specter, p. 490
Dirt and Disease. Polio Before FDR.
Naomi Rogers
Review author[s]: Rima D. Apple
Books Received, pp. 490-491


Back Matter (23 pp.)

Previous Issue: New Series, Vol. 258, No. 5080, Oct. 9, 1992
Next Issue: New Series, Vol. 258, No. 5082, Oct. 23, 1992



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