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Science, New Series, Vol. 258, No. 5080, Oct. 9, 1992


Previous Issue: New Series, Vol. 258, No. 5079, Genome Issue, Oct. 2, 1992
Next Issue: New Series, Vol. 258, No. 5081, Oct. 16, 1992


Front Matter (45 pp.)
Editorial: The Dimensions of the Brain, p. 199
Daniel E. Koshland, Jr.


Policy Forum
Rational Science, Irrational Reality: A Congressional Perspective on Basic Research and Society, pp. 200-201
George E. Brown, Jr.


Letters
Drugs from Third World Plants: The Future, pp. 203-204
Carl Djerassi
Space Station Freedom, pp. 204-205
Robert W. Phillips
Landsats Old and New, p. 205
Alden P. Colvocoresses


Corrections and Clarifications: Block of Ca 2+ wave Ca 2+ Oscillation by Antibody to the Inositol 1,4,5-Trisphosphate Receptor in Fertilized Hamster Eggs, p. 205
ScienceScope, p. 207
David P. Hamilton


News and Comment
R&D Budget Collides With the Deficit, pp. 208-209
Eliot Marshall; David P. Hamilton
Top HHS Lawyer Seeks to Block NIH, pp. 209-210
Leslie Roberts
Did Political Clout Win Vaccine Trial for MicroGeneSys?, p. 211
Jon Cohen
HHS `Violence Initiative' Caught in a Crossfire, pp. 212-213
Richard Stone
Violence Epidemiologists Test The Hazards of Gun Ownership, pp. 213-215
Gary Taubes


Research News
The Brain Remaps Its Own Contours, pp. 216-218
Marcia Barinaga
New Optimism Blooms for Developing Treatments, pp. 218-220
John Travis
A Revisionist Timetable for The Ice Ages, pp. 220-221
Richard A. Kerr
Deep-Living Microbes Mount A Relentless Attack on Rock, p. 222
Tim Appenzeller


Random Samples, p. 223
Constance Holden


Perspectives: Focus on Neuroscience
Dividing Up the Neocortex, pp. 237-238
Carla J. Shatz
Circadian Clock Genes Are Ticking, pp. 238-240
Joseph S. Takahashi
Ion Channel Structure and Function, pp. 240-241
Christopher Miller
Bench to Bedside: The Glutamate Connection, pp. 241-243
Dennis W. Choi
Are Adult Learning Mechanisms Also Used for Development?, pp. 243-245
Eric R. Kandel; Thomas J. O'Dell
The Physiology of Memory: Recordings of Things Past, pp. 245-246
Robert Desimone


Continuous 500,000-Year Climate Record from Vein Calcite in Devils Hole, Nevada, pp. 255-260
Isaac J. Winograd; Tyler B. Coplen; Jurate M. Landwehr; Alan C. Riggs; Kenneth R. Ludwig; Barney J. Szabo; Peter T. Kolesar; Kinga M. Revesz

Rodent Carcinogens: Setting Priorities, pp. 261-265
Lois Swirsky Gold; Thomas H. Slone; Bonnie R. Stern; Neela B. Manley; Bruce N. Ames


Reports
Compositional Trends in Rock-Forming Elements of Comet Halley Dust, pp. 266-269
M. N. Fomenkova; J. F. Kerridge; K. Marti; L.-A. McFadden
X-ray Laser Microscopy of Rat Sperm Nuclei, pp. 269-271
L. B. Da Silva; J. E. Trebes; R. Balhorn; S. Mrowka; E. Anderson; D. T. Attwood; T. W. Barbee, Jr.; J. Brase; M. Corzett; J. Gray; J. A. Koch; C. Lee; D. Kern; R. A. London; B. J. MacGowan; D. L. Matthews; G. Stone
Room-Temperature, Electric Field-Induced Creation of Stable Devices in CulnSe2 Crystals, pp. 271-274
David Cahen; Jean-Marc Gilet; Claus Schmitz; Leonid Chernyak; Konstantin Gartsman; Abram Jakubowicz
Observations of the Liquid-Crystal Analog of the Abrikosov Phase, pp. 275-278
K. J. Ihn; J. A. N. Zasadzinski; R. Pindak; A. J. Slaney; J. Goodby
Microbial Control of Silicate Weathering in Organic-Rich Ground Water, pp. 278-281
Franz K. Hiebert; Philip C. Bennett
Fault Zone Connectivity: Slip Rates on Faults in the San Francisco Bay Area, California, pp. 281-284
Roger Bilham; Paul Bodin
Mass-Spectrometric 230 Th- 234 U- 238 U Dating of the Devils Hole Calcite Vein, pp. 284-287
Kenneth R. Ludwig; Kathleen R. Simmons; Barney J. Szabo; Isaac J. Winograd; Jurate M. Landwehr; Alan C. Riggs; Ray J. Hoffman
Regulation of the Amount of Starch in Plant Tissues by ADP Glucose Purophosphorylase, pp. 287-292
David M. Stark; Kurt P. Timmerman; Gerard F. Barry; Jack Preiss; Ganesh M. Kishore
Intercellular Propagation of Calcium Waves Mediated by Inositol Trisphosphate, pp. 292-295
Scott Boitano; Ellen R. Dirksen; Michael J. Sanderson
Inhibition of Neutrophil Chemokinesis on Vitronectin by Inhibitors of Calcineurin, pp. 296-299
Bill Hendey; Claude B. Klee; Frederick R. Maxfield
Diverse Migratory Pathways in the Developing Cerebral Cortex, pp. 299-302
Nancy A. O'Rourke; Michael E. Dailey; Stephen J. Smith; Susan K. McConnell
Prevention of Programmed Cell Death of Sympathetic Neurons by the bcl-2 Proto-Oncogene, pp. 302-304
Irène Garcia; Isabelle Martinou; Yoshihide Tsujimoto; Jean-Claude Martinou
Release of Alzheimer Amyloid Precursor Derivatives Stimulated by Activation of Muscarinic Acetylcholine Receptors, pp. 304-307
Roger M. Nitsch; Barbara E. Slack; Richard J. Wurtman; John H. Growdon
Acetylcholine Receptor Channel Structure Probed in Cysteine-Substitution Mutants, pp. 307-310
Myles H. Akabas; David A. Stauffer; Ming Xu; Arthur Karlin
Calcium Channels Coupled to Glutamate Release Identified by ω-Aga-IVA, pp. 310-313
Timothy J. Turner; Michael E. Adams; Kathleen Dunlap
Effects of Kinesin Mutations on Neuronal Functions, pp. 313-316
M. Gho; K. McDonald; B. Ganetzky; W. M. Saxton


Technical Comments
The Dispersion of Neuronal Clones Across the Cerebral Cortex, pp. 317-320
Thomas B. L. Kirkwood; Jack Price; Elizabeth A. Grove; Christopher Walsh; Constance L. Cepko; Elizabeth F. Ryder; George M. Church; Cliff Tabin


Book Reviews
A Publicist for Pragmatism, pp. 333-334
A Scientist's Voice in American Culture. Simon Newcomb and the Rhetoric of Scientific Method.
Albert E. Moyer
Review author[s]: Timothy L. Alborn
Medicalizations, pp. 334-335
Framing Disease. Studies in Cultural History.
Charles E. Rosenberg; Janet Golden
Review author[s]: Peter Conrad
Cosmic Backgrounds, p. 335
The Early Observable Universe from Diffuse Backgrounds.
B. Rocca-Volmerange; J. M. Deharveng; J. Tran Thanh Van
Review author[s]: Grant J. Mathews
The Smectic C* Phase, pp. 335-336
Ferroelectric Liquid Crystals. Principles, Properties, and Applications.
J. W. Goodby; Robert Blinc; Noel A. Clark; Sven T. Lagerwall; M. A. Osipov; S. A. Pikin; Takao Sakurai; Katsumi Yoshino; Boštjan Žekš
Review author[s]: Harald Pleiner
Books Received, pp. 336-337


Back Matter (31 pp.)

Previous Issue: New Series, Vol. 258, No. 5079, Genome Issue, Oct. 2, 1992
Next Issue: New Series, Vol. 258, No. 5081, Oct. 16, 1992



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