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Science, New Series, Vol. 258, No. 5082, Oct. 23, 1992


Previous Issue: New Series, Vol. 258, No. 5081, Oct. 16, 1992
Next Issue: New Series, Vol. 258, No. 5083, Oct. 30, 1992


Front Matter (24 pp.)
Editorial: Science in Japan, p. 527
Daniel E. Koshland, Jr.


Letters
The Readers' NIH, pp. 529-532
Donald D. Brown; John H. Barton; Barbara Hatch Rosenberg; C. Paul Bianchi; Ian Stevenson; Thomas C. K. Chan; Alan Peter Rudell; Charles A. Gardner; Denis Pelli; George M. Malacinski; Sebastian Doniach; Tom Frederick; Kevin Jon Williams; Alan F. Hofmann; Ajit Varki


ScienceScope, p. 535
David P. Hamilton


News and Comment
Lobbying for an AIDS Trial, pp. 536-539
Jon Cohen
IOM Weighs in on Microbial Threat, p. 540
Richard Stone
Shakeup Splits Space Science, p. 540
Eliot Marshall
Outcry Shoots Down Funding Reform, p. 541
Eliot Marshall
Study Flunks Science and Math Tests, p. 541
Constance Holden
U.S. Researchers Gather A Bumper Crop of Laurels, pp. 542-545
Jean Marx; Tim Appenzeller; Ivan Amato; Anne Simon Moffat
Biology: There's Honor Outside Stockholm, p. 545
John Travis


Research News
Measles Battle Loses Potent Weapon, pp. 546-547
Rick Weiss
Theoreticians Are Putting a New Spin on the Planets, p. 548
Richard A. Kerr
Found: Messengers From The Interstellar Medium, p. 549
Faye Flam
Familial Alzheimer's Linked To Chromosome 14 Gene, p. 550
Jean Marx


Random Samples, p. 551
Constance Holden


Science In Japan


News Reports
The Scientific Geography of Japan, pp. 562-563
Japanese Academics Bemoan The Cost of Years of Neglect, pp. 564-565+567-569
Alun Anderson
Women Scientists: It's Lonely at the Top, p. 566
Fred Myers
Industry Steps in to Fill the Gap in Basic Research, pp. 570-571
David P. Hamilton
Has Tsukuba Put Its Worst Days Behind It?, p. 572
David P. Hamilton
Diversity Flourishes in Japan's Research Labs, pp. 573-576
A. A.; D. P. H.; F. M.
Bright Dreams Despite a Legacy of Hits and Misses, p. 577
Alun Anderson; David P. Hamilton


Historical Viewpoint
Early Cultivators of Science in Japan, pp. 578-580
Akihito


Perspectives
The Real World Computing Program: MITI's Next Computer Research Initiative, pp. 581-582
Akinori Yonezawa
Public and Private Support of Basic Research in Japan, pp. 582-583
Yukihiro Hirano
Organic Synthesis: Current Status in Japan, pp. 584-585
Ryoji Noyori
Has Japan Begun to Move Toward Atomic Level Material Processing?, pp. 586-587
M. Aono
Astronomy in Japan, pp. 587-588
Yasuo Tanaka
The Challenge of Joint Research in Japan, pp. 589-590
Kenkichiro Koizumi
Underfunding of Basic Science in Japan, pp. 590-591
Akito Arima
Seppuku and Autoimmunity, pp. 591-592
Tasuku Honjo

Interleukin-6 and Its Receptor: A Paradigm for Cytokines, pp. 593-597
Tadamitsu Kishimoto; Shizuo Akira; Tetsuya Taga
Molecular Diversity of Glutamate Receptors and Implications for Brain Function, pp. 597-603
Shigetada Nakanishi
Multistep Carcinogenes: A 1992 Perspective, pp. 603-607
Takashi Sugimura
Intracellular Signaling by Hydrolysis of Phospholipids and Activation of Protein Kinase C, pp. 607-614
Yasutomi Nishizuka
The Economics of Health Care in Japan, pp. 614-618
Naoki Ikegami
The Yohkoh Mission for High-Energy Solar Physics, pp. 618-625
L. Acton; S. Tsuneta; Y. Ogawara; R. Bentley; M. Bruner; R. Canfield; L. Culhane; G. Doschek; E. Hiei; T. Hirayama; H. Hudson; T. Kosugi; J. Lang; J. Lemen; J. Nishimura; K. Makishima; Y. Uchida; T. Watanabe
Seismic Tomogram of the Earth's Mantle: Geodynamic Implications, pp. 625-630
Yoshio Fukao


Reports
A Priori Evaluation of Aqueous Polarization Effects Through Monte Carlo QM-MM Simulations, pp. 631-635
Jiali Gao; Xinfu Xia
Mercury Radar Imaging: Evidence for Polar Ice, pp. 635-640
Martin A. Slade; Bryan J. Butler; Duane O. Muhleman
Radar Mapping of Mercury: Full-Disk Images and Polar Anomalies, pp. 640-643
J. K. Harmon; M. A. Slade
The Thermal Stability of Water Ice at the Poles of Mercury, pp. 643-646
David A. Paige; Stephen E. Wood; Ashwin R. Vasavada
Biological Weighting Function for the Inhibition of Phytoplankton Photosynthesis by Ultraviolet Radiation, pp. 646-650
John J. Cullen; Patrick J. Neale; Michael P. Lesser
Hemoglobin-AGE: A Circulating Marker of Advanced Glycosylation, pp. 651-653
Zenji Makita; Helen Vlassara; Elliot Rayfield; Kenneth Cartwright; Eli Friedman; Roger Rodby; Anthony Cerami; Richard Bucala
Negative Selection of Precursor Thymocytes Before Their Differentiation into CD4+CD8+ Cells, pp. 653-656
Yousuke Takahama; Elizabeth W. Shores; Alfred Singer
Flow-Dependent Cytosolic Acidification of Vascular Endothelial Cells, pp. 656-659
Roy C. Ziegelstein; Linda Cheng; Maurizio C. Capogrossi
Role of Transmembrane Domain Interactions in the Assembly of Class II MHC Molecules, pp. 659-662
Pierre Cosson; Juan S. Bonifacino
Phase Coupling by Synaptic Spread in Chains of Coupled Neuronal Oscillators, pp. 662-665
Thelma L. Williams
Burst Firing in Dopamine Neurons Induced by N-Methyl-d-Aspartate: Role of Electrogenic Sodium Pump, pp. 665-667
Steven W. Johnson; Vincent Seutin; R. Alan North
Genetic Linkage Evidence for a Familial Alzheimer's Disease Locus on Chromosome 14, pp. 668-671
Gerard D. Schellenberg; Thomas D. Bird; Ellen M. Wijsman; Harry T. Orr; Leojean Anderson; Ellen Nemens; June A. White; Lori Bonnycastle; James L. Weber; M. Elisa Alonso; Huntington Potter; Leonard L. Heston; George M. Martin


Technical Comments
Theory and Experiment in High-Temperature Superconductivity, p. 672
J. E. Hirsch; P. W. Anderson


Book Reviews
Technomiracles Revisited, pp. 674-675
Route 128. Lessons from Boston's High-Tech Community.
Susan Rosegrant; David Lampe
Technology in the Garden. Research Parks and Regional Economic Development.
Michael I. Luger; Harvey A. Goldstein
Review author[s]: AnnaLee Saxenian
After the Wall, pp. 675-676
Research and Technology in the Former German Democratic Republic.
Raymond Bentley
Review author[s]: Raymond G. Stokes
An Era of Electro-Optics, pp. 676-678
The Laser in America, 1950-1970.
Joan Lisa Bromberg
Review author[s]: John Whinnery
Books Received, p. 678


Back Matter (34 pp.)

Previous Issue: New Series, Vol. 258, No. 5081, Oct. 16, 1992
Next Issue: New Series, Vol. 258, No. 5083, Oct. 30, 1992



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