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Science, New Series, Vol. 286, No. 5440, Oct. 22, 1999


Previous Issue: New Series, Vol. 286, No. 5439, Oct. 15, 1999
Next Issue: New Series, Vol. 286, No. 5441, Oct. 29, 1999


Front Matter (44 pp.)
Netwatch, p. 639
Laura Helmuth


News


News of the Week
Enzymes Point Way to Potential Alzheimer's Therapies, pp. 650-651
Elizabeth Pennisi
Science Supporter John Porter to Leave Congress, p. 651
Eliot Marshall
Massive Hiring Plan Aimed at 'Brain Gain', pp. 651+653
Wayne Kondro
ScienceScope, pp. 653+655
Secret of Soviet-Era Nuclear Blast Revealed, pp. 653-654
Vladimir Pokrovsky
On the Track of Ebola's Hideout?, pp. 654-655
Michael Hagmann
PNAS to Join PubMed Central-On Condition, pp. 655-656
Eliot Marshall
The Lancet Scolded Over Pusztai Paper, p. 656
Martin Enserink
Did One California Jolt Bring on Another, pp. 656-657
Richard A. Kerr
New Questions About Ancient American Site, pp. 657+659
Heather Pringle
Scientists Strike Back Against Creationism, p. 659
Bernice Wuethrich


News Focus
Prions: A Lone Killer or a Vital Accomplice?, pp. 660-662
Michael Balter
A Surprising Tale of Life in the City, p. 663
Keith Kloor
Do Mitochondrial Mutations Dim the Fire of Life?, p. 664
Elizabeth Pennisi
A New Blocker for the TGF-β Pathway, p. 665
Gretchen Vogel
Colleagues Say 'Amen' to This Year's Choices, pp. 666-667+669
Michael Hagmann; Alexander Hellemans; Robert F. Service; Mark Sincell


Random Samples, p. 671
Richard Stone


Science's Compass


Editorial
New Online Tools for Scholars: 3, p. 679
Floyd E. Bloom


Letters
Science and Scripture, p. 681
John W. Moore; Fred Whitehead; Gayle Brosnan-Watters
Postdoc Servitude in the Academic-Industrial Alliance, pp. 681-682
Leonard John Deftos
Don't Try This at Home, p. 682
Sanjay Magavi
Foreign-Born Scientists, pp. 682-684
Alan Chodos; Robert M. Chandler-Burns; Norma P. Martinez de Guzman; Armando Guzman; Sharon G. Levin; Paula E. Stephan
Documenting Speciation, p. 684
John S. Knox
Corrections and Clarifications: Ethical Loophole Closing up for Stem Cell Researchers, p. 684
Corrections and Clarifications: Water Vapor Absorption in Arthropods by Accumulation of Myoinositol and Glucose, p. 684
Corrections and Clarifications: Effect on the Biosphere of Elevated Atmospheric CO2, p. 684
Corrections and Clarifications: Redesigning Evolution?, p. 684


Policy Forum
International Ecosystem Assessment, pp. 685-686
Edward Ayensu; Daniel van R. Claasen; Mark Collins; Andrew Dearing; Louise Fresco; Madhav Gadgil; Habiba Gitay; Gisbert Glaser; Calestous Juma; John Krebs; Robert Lenton; Jane Lubchenco; Jeffrey A. McNeely; Harold A. Mooney; Per Pinstrup-Andersen; Mario Ramos; Peter Raven; Walter V. Reid; Cristian Samper; José Sarukhán; Peter Schei; José Galízia Tundisi; Robert T. Watson; Xu Guanhua; A. H. Zakri


Books et al.
Complex Facets of a Strong Interactor, p. 687
Strange Beauty. Murray Gell-Mann and the Revolution in Twentieth-Century Physics.
George Johnson
Review author[s]: Mary K. Gaillard


Perspectives
Cranking It Up a Notch, pp. 689-690
Anjen Chenn; Christopher A. Walsh
Do Proteins Predate DNA?, pp. 690-692
Stephen J. Freeland; Robin D. Knight; Laura F. Landweber
Mapping Mantle Melting, pp. 692-693
Roger Buck
From Gamma-Ray Bursts to Supernovae, pp. 693+695
Jan van Paradijs


Olfaction
Making Sense of Scents, p. 703
Peter Stern; Jean Marx


News
Following the Scent of Avian Olfaction, pp. 704-705
David Malakoff
Salmon Follow Watery Odors Home, pp. 705-706
Marcia Barinaga


Reviews
Seven-Transmembrane Proteins as Odorant and Chemosensory Receptors, pp. 707-711
Peter Mombaerts
The Olfactory Bulb: Coding and Processing of Odor Molecule Information, pp. 711-715
Kensaku Mori; Hiroshi Nagao; Yoshihiro Yoshihara
The Vomeronasal Organ, pp. 716-720
Eric B. Keverne
Olfactory Reception in Invertebrates, pp. 720-723
Jürgen Krieger; Heinz Breer
A Systems Perspective on Early Olfactory Coding, pp. 723-728
Gilles Laurent


Research


Research Articles
β-Secretase Cleavage of Alzheimer's Amyloid Precursor Protein by the Transmembrane Aspartic Protease BACE, pp. 735-741
Robert Vassar; Brian D. Bennett; Safura Babu-Khan; Steve Kahn; Elizabeth A. Mendiaz; Paul Denis; David B. Teplow; Sandra Ross; Patricia Amarante; Richard Loeloff; Yi Luo; Seth Fisher; Janis Fuller; Steven Edenson; Jackson Lile; Mark A. Jarosinski; Anja Leona Biere; Eileen Curran; Teresa Burgess; Jean-Claude Louis; Frank Collins; James Treanor; Gary Rogers; Martin Citron
Contact-Dependent Inhibition of Cortical Neurite Growth Mediated by Notch Signaling, pp. 741-746
Nenad Šestan; Spyros Artavanis-Tsakonas; Pasko Rakic


Reports
All-Inorganic Field Effect Transistors Fabricated by Printing, pp. 746-749
Brent A. Ridley; Babak Nivi; Joseph M. Jacobson
Bidirectional Semiconductor Laser, pp. 749-752
Claire Gmachl; Alessandro Tredicucci; Deborah L. Sivco; Albert L. Hutchinson; Federico Capasso; Alfred Y. Cho
Asymmetric Electrical Structure in the Mantle Beneath the East Pacific Rise at 17°S, pp. 752-756
R. L. Evans; P. Tarits; A. D. Chave; A. White; G. Heinson; J. H. Filloux; H. Toh; N. Seama; H. Utada; J. R. Booker; M. J. Unsworth
Subtropical North Atlantic Temperatures 60,000 to 30,000 Years Ago, pp. 756-759
Julian P. Sachs; Scott J. Lehman
Evolution of Complexity in Paleozoic Ammonoid Sutures, pp. 760-763
W. B. Saunders; D. M. Work; S. V. Nikolaeva
A Triassic Fauna from Madagascar, Including Early Dinosaurs, pp. 763-765
John J. Flynn; J. Michael Parrish; Berthe Rakotosamimanana; William F. Simpson; Robin L. Whatley; André R. Wyss
Interlocked Feedback Loops Within the Drosophila Circadian Oscillator, pp. 766-768
Nick R. J. Glossop; Lisa C. Lyons; Paul E. Hardin
Light-Independent Role of CRY1 and CRY2 in the Mammalian Circadian Clock, pp. 768-771
Edmund A. Griffin, Jr.; David Staknis; Charles J. Weitz
Negative Feedback Regulation of TGF-β Signaling by the SnoN Oncoprotein, pp. 771-774
Shannon L. Stroschein; Wei Wang; Sharleen Zhou; Qiang Zhou; Kunxin Luo
Aging-Dependent Large Accumulation of Point Mutations in the Human mtDNA Control Region for Replication, pp. 774-779
Yuichi Michikawa; Franca Mazzucchelli; Nereo Bresolin; Guglielmo Scarlato; Giuseppe Attardi
Crystal Structure of the Ectodomain of Human Transferrin Receptor, pp. 779-782
C. Martin Lawrence; Sanjoy Ray; Marina Babyonyshev; Renate Galluser; David W. Borhani; Stephen C. Harrison
Microtubule Disassembly by ATP-Dependent Oligomerization of the AAA Enzyme Katanin, pp. 782-785
James J. Hartman; Ronald D. Vale
Neuronal Activity-Dependent Cell Survival Mediated by Transcription Factor MEF2, pp. 785-790
Zixu Mao; Azad Bonni; Fen Xia; Mireya Nadal-Vicens; Michael E. Greenberg
Apoptosis of T Cells Mediated by Ca 2+ -Induced Release of the Transcription Factor MEF2, pp. 790-793
Hong-Duk Youn; Luo Sun; Ron Prywes; Jun O. Liu


Back Matter (67 pp.)

Previous Issue: New Series, Vol. 286, No. 5439, Oct. 15, 1999
Next Issue: New Series, Vol. 286, No. 5441, Oct. 29, 1999



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