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Science, New Series, Vol. 275, No. 5298, Jan. 17, 1997


Previous Issue: New Series, Vol. 275, No. 5297, Jan. 10, 1997
Next Issue: New Series, Vol. 275, No. 5299, Jan. 24, 1997


Front Matter (24 pp.)
Editorial: Financial Interests Constrain Drug Development, p. 287
Silvio Garattini


Letters
ITER Forecasts, pp. 289-292
David E. Baldwin; Richard D. Hazeltine; Ronald C. Davidson; Miklos Porkolab; Marshall N. Rosenbluth; D. C. Robinson; Edmund J. Synakowski; W. Dorland; M. Kotschenreuther; G. W. Hammett
Balkanization by Internet?, p. 293
Massimo Battaglia; Christopher Weed


Corrections and Clarifications: Turbulance May Sink Titanic Reactor, p. 293
ScienceScope, p. 295
Jocelyn Kaiser


News and Comment
Selling Science: At What Price?, pp. 296-297
Andrew Lawler
Judgment Pries Open Expert Panel, p. 297
Jocelyn Kaiser
The Media's Love Affair with AIDS Research: Hope vs. Hype, pp. 298-299
Jon Cohen
African Malaria Studies Draw Attention, p. 299
Eliot Marshall
NSF Prepares to Dish Up Millimeter Array Project, pp. 300-301
Jeffrey Mervis
How to Get Databases Talking the Same Language, pp. 301-302
Nigel Williams
SINQ Quickens Pulse to Cool Its Beams, p. 302
Alexander Hellemans


Research News
Making Single Electrons Compute, pp. 303-304
Robert F. Service
Integrating the Biological Sciences in New Mexico, pp. 305-306
Elizabeth Pennisi
New "Guiding" Protein Discovered, p. 306
Jocelyn Kaiser
Putting a Quantum Computer to Work in a Cup of Coffee, pp. 307-309
Gary Taubes
Yangtze Seen as Earliest Rice Site, p. 309
Dennis Normile
Center Seeks Synthesis to Make Ecology More Useful, pp. 310-311
Yvonne Baskin


Random Samples, p. 313
Constance Holden


Book Reviews
The AIDS Engagement, p. 320
Impure Science. AIDS, Activism, and the Politics of Knowledge.
Steven Epstein
Review author[s]: Ronald Bayer
A Technical Alliance, p. 321
Top Secret Exchange. The Tizard Mission and the Scientific War.
David Zimmerman
Review author[s]: Louis Brown
Martian Substances, p. 321
Water on Mars.
Michael H. Carr
Review author[s]: Fraser Fanale


Perspectives
Polymorphic Phase Transitions in Liquids and Glasses, pp. 322-323
Peter H. Poole; Tor Grande; C. Austen Angell; Paul F. McMillan
Chaotic Beetles, pp. 323-324
Charles Godfray; Michael Hassell
Synapse Elimination: For Nerves It's All or Nothing, pp. 324-325
Eric Frank


Bioinformatics
Information Retrieval in Digital Libraries: Bringing Search to the Net, pp. 327-334
Bruce R. Schatz
Mathematical and Computational Challenges in Population Biology and Ecosystems Science, pp. 334-343
Simon A. Levin; Bryan Grenfell; Alan Hastings; Alan S. Perelson
An Information-Intensive Approach to the Molecular Pharmacology of Cancer, pp. 343-349
John N. Weinstein; Timothy G. Myers; Patrick M. O'Connor; Stephen H. Friend; Albert J. Fornace Jr.; Kurt W. Kohn; Tito Fojo; Susan E. Bates; Lawrence V. Rubinstein; N. Leigh Anderson; John K. Buolamwini; William W. van Osdol; Anne P. Monks; Dominic A. Scudiero; Edward A. Sausville; Daniel W. Zaharevitz; Barry Bunow; Vellarkad N. Viswanadhan; George S. Johnson; Robert E. Wittes; Kenneth D. Paull


Research Articles
Bulk Spin-Resonance Quantum Computation, pp. 350-356
Neil A. Gershenfeld; Isaac L. Chuang
Alterations in Synaptic Strength Preceding Axon Withdrawal, pp. 356-361
H. Colman; J. Nabekura; J. W. Lichtman


Reports
Stereoselective Bimolecular Phenoxy Radical Coupling by an Auxiliary (Dirigent) Protein Without an Active Center, pp. 362-366
Laurence B. Davin; Huai-Bin Wang; Anastasia L. Crowell; Diana L. Bedgar; Diane M. Martin; Simo Sarkanen; Norman G. Lewis
Reconstruction of Current Flow and Imaging of Current-Limiting Defects in Polycrystalline Superconducting Films, pp. 367-369
A. E. Pashitski; A. Gurevich; A. A. Polyanskii; D. C. Larbalestier; A. Goyal; E. D. Specht; D. M. Kroeger; J. A. DeLuca; J. E. Tkaczyk
Hillslope Evolution by Bedrock Landslides, pp. 369-372
Alexander L. Densmore; Robert S. Anderson; Brian G. McAdoo; Michael A. Ellis
An Explanation for Earth's Long-Term Rotational Stability, pp. 372-375
Mark A. Richards; Yannick Ricard; Carolina Lithgow-Bertelloni; Giorgio Spada; Roberto Sabadini
Depletion of the Outer Asteroid Belt, pp. 375-377
Jer-Chyi Liou; Renu Malhotra
Kinetic Measurement of the Step Size of DNA Unwinding by Escherichia coli UvrD Helicase, pp. 377-380
Janid A. Ali; Timothy M. Lohman
Receptor and βγ Binding Sites in the α Subunit of the Retinal G Protein Transducin, pp. 381-384
René Onrust; Paul Herzmark; Patty Chi; Pablo D. Garcia; Olivier Lichtarge; Chris Kingsley; Henry R. Bourne
Consumer Versus Resource Control in Freshwater Pelagic Food Webs, pp. 384-386
Michael T. Brett; Charles R. Goldman
Functional Specificity among Hsp70 Molecular Chaperones, pp. 387-389
Philip James; Christine Pfund; Elizabeth A. Craig
Chaotic Dynamics in an Insect Population, pp. 389-391
R. F. Costantino; R. A. Desharnais; J. M. Cushing; Brian Dennis
A Mouse Model with Features of Familial Combined Hyperlipidemia, pp. 391-394
Lori Masucci-Magoulas; Ira J. Goldberg; Charles L. Bisgaier; Humaira Serajuddin; Omar L. Francone; Jan L. Breslow; Alan R. Tall
Linkage of G Protein-Coupled Receptors to the MAPK Signaling Pathway Through PI 3-Kinase γ, pp. 394-397
Marco Lopez-Llasaca; Piero Crespo; P. Giuseppe Pellici; J. Silvio Gutkind; Reinhard Wetzker
Uniting Two General Patterns in the Distribution of Species, pp. 397-400
Iikka Hanski; Mats Gyllenberg
Reduced Ubiquitin-Dependent Degradation of c-Jun After Phosphorylation by MAP Kinases, pp. 400-402
Anna Maria Musti; Mathias Treier; Dirk Bohmann
Transmission of the BSE Agent to Mice in the Absence of Detectable Abnormal Prion Protein, pp. 402-405
Corinne I. Lasmézas; Jean-Philippe Deslys; Olivier Robain; Alexandre Jaegly; Vincent Beringue; Jean-Michel Peyrin; Jean-Guy Fournier; Jean-Jacques Hauw; Jean Rossier; Dominique Dormont


Technical Comments
Potency of Combined Estrogenic Pesticides, pp. 405-406
Kavita Ramamoorthy; Fan Wang; I-Chen Chen; Stephen Safe; John D. Norris; Donald P. McDonnell; Kevin W. Gaido; Wayne P. Bocchinfuso; Kenneth S. Korach; John A. McLachlan; Steven F. Arnold; Diane M. Klotz; Bridgette M. Collins; Peter M. Vonier; Louis J. Guillette
Redox Stabilization of the Atmosphere and Oceans and Marine Productivity, pp. 406-408
Albert S. Colman; Fred T. Mackenzie; Heinrich D. Holland; P. Van Cappellen; E. D. Ingall
Polyalanine Expansion in Synpolydactyly Might Result from Unequal Crossing- Over of HOXD13, pp. 408-409
Stephen T. Warren; Yasuteru Muragaki; Stefan Mundlos; Joseph Upton; Bjorn R. Olsen


Back Matter (35 pp.)

Previous Issue: New Series, Vol. 275, No. 5297, Jan. 10, 1997
Next Issue: New Series, Vol. 275, No. 5299, Jan. 24, 1997



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