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Science, New Series, Vol. 264, No. 5167, Jun. 24, 1994


Previous Issue: New Series, Vol. 264, No. 5166, Jun. 17, 1994
Next Issue: New Series, Vol. 265, No. 5168, Jul. 1, 1994


Front Matter (25 pp.)
Editorial: Progress in Parasitology, p. 1827
Richard B. Gallagher; Jean Marx; Pamela J. Hines


Letters
Sedimentology of the K-T Boundary, p. 1829
H. Edward Clifton; R. H. Dott Jr.
Dioxin Effects, pp. 1829-1830
G. M. Reggiani
Quantum Uncertainty Principle: No Loopholes, pp. 1830-1831
Julian Schwinger
History Lesson, p. 1831
Carolyn A. Carr


Corrections and Clarifications: Animal Tests Take Back Seat to Clinical Data, p. 1831
Corrections and Clarifications: Rules for α-Helix Termination by Glycine, p. 1831
ScienceScope, p. 1835
Richard Stone


News and Comment
NSF Eyes New South Pole Station, pp. 1836+1837-1838
Jeffrey Mervis
A Design for Life in the Freezer, p. 1837
Christopher Anderson
U.S. Panel Votes to Delay Real-World Vaccine Trials, p. 1839
Jon Cohen
In Midst of a Freeze, Science Minister Calls for Expansion, pp. 1840+1841
Michael Balter
Quantity No Longer Counts in Britain, p. 1840
Claire O'Brien
Misconduct Panel Sets Ambitious Agenda, p. 1841
Christopher Anderson
Crane Experiment Finally Perches in Washington State, p. 1842
Virginia Morell


Research News
The Inner Sanctum of the Proton, pp. 1843-1844
Faye Flam
Lucky Break for Kidney Disease Gene, p. 1844
Claire O'Brien
A Dark Matter Recipe is Tested-And Found Wanting, p. 1845
Ray Jayawardhana
A Challenge to p16 Gene as a Major Tumor Suppressor, p. 1846
Jean Marx
A New Test Gives Early Warning of a Growing Killer, pp. 1847-1848
Rachel Nowak
Genome Initiatives Tackle Developing World's Big Killers, pp. 1848-1849
Peter Aldhous


Random Samples, pp. 1850-1851
Lisa Seachrist


Parasitology


News Reports
Fighting Parasites on a Shoestring, pp. 1857-1859
Peter Aldhous
Finding 'Sustainable' Ways to Prevent Parasitic Diseases, pp. 1859-1861
Rebecca Kolberg
Models Aid Understanding, Help Control Parasites, pp. 1862-1863
Billy Goodman


Policy Forums
Fighting the Parasites of Poverty: Public Research, Private Industry, and Tropical Diseases, pp. 1864-1866
Tore Godal
Economics and the Argument for Parasitic Disease Control, pp. 1866-1867
David B. Evans; Dean T. Jamison


Perspectives
Unusual Strategies of Gene Expression and Control in Parasites, pp. 1868-1869
Timothy W. Nilsen
RNA Editing and the Evolution of Parasites, pp. 1870-1871
Larry Simpson; Dmitri A. Maslov
Antigenic Variation in African Trypanosomes, pp. 1872-1873
Piet Borst; Gloria Rudenko
Vector Biology and the Control of Malaria in Africa, pp. 1874-1875
Frank H. Collins; Nora J. Besansky
Immunoglobulin E and Effector Cells in Schistosomiasis, pp. 1876-1877
Monique Capron; André Capron

Malaria Pathogenesis, pp. 1878-1883
Louis H. Miller; Michael F. Good; Geneviève Milon
Mathematical Studies of Parasitic Infection and Immunity, pp. 1884-1886
Roy M. Anderson


Low-Barrier Hydrogen Bonds and Enzymic Catalysis, pp. 1887-1890
W. W. Cleland; Maurice M. Kreevoy


Research Article
Structures of Ternary Complexes of Rat DNA Polymerase β, a DNA Template-Primer, and ddCTP, pp. 1891-1903
Huguette Pelletier; Michael R. Sawaya; Amalendra Kumar; Samuel H. Wilson; Joseph Kraut


Reports
Asymmetric Phase Effects and Mantle Convection Patterns, pp. 1904-1907
Mian Liu
African Homo erectus: Old Radiometric Ages and Young Oldowan Assemblages in the Middle Awash Valley, Ethiopia, pp. 1907-1910
J. D. Clark; J. de Heinzelin; K. D. Schick; W. K. Hart; T. D. White; G. WoldeGabriel; R. C. Walter; G. Suwa; B. Asfaw; E. Vrba; Y. H.-Selassie
MCM-22: A Molecular Sieve with Two Independent Multidimensional Channel Systems, pp. 1910-1913
Michael E. Leonowicz; Jeffrey A. Lawton; Stephen L. Lawton; Mae K. Rubin
Time-Resolved Imaging of Translucent Droplets in Highly Scattering Turbid Media, pp. 1913-1915
R. R. Alfano; X. Liang; L. Wang; P. P. Ho
The X-Ray Surface Forces Apparatus: Structure of a Thin Smectic Liquid Crystal Film Under Confinement, pp. 1915-1918
Stefan H. J. Idziak; Cyrus R. Safinya; Robert S. Hill; Keith E. Kraiser; Marina Ruths; Heidi E. Warriner; Suzi Steinberg; Keng S. Liang; Jacob N. Israelachvili
Functional Role of Type I and Type II Interferons in Antiviral Defense, pp. 1918-1921
Ulrike Müller; Ulrich Steinhoff; Luiz F. L. Reis; Silvio Hemmi; Jovan Pavlovic; Rolf M. Zinkernagel; Michel Aguet
Involvement of the IRF-1 Transcription Factor in Antiviral Responses to Interferons, pp. 1921-1924
Tohru Kimura; Katsutoshi Nakayama; Josef Penninger; Motoo Kitagawa; Hisashi Harada; Toshifumi Matsuyama; Nobuyuki Tanaka; Ryutaro Kamijo; Jan Vilček; Tak W. Mak; Tadatsugu Taniguchi
Expanding the Scope of RNA Catalysis, pp. 1924-1927
James R. Prudent; Tetsuo Uno; Peter G. Schultz
A Low-Barrier Hydrogen Bond in the Catalytic Triad of Serine Proteases, pp. 1927-1930
Perry A. Frey; Sean A. Whitt; John B. Tobin
Crystal Structure of Rat DNA Polymerase β: Evidence for a Common Polymerase Mechanism, pp. 1930-1935
Michael R. Sawaya; Huguette Pelletier; Amalendra Kumar; Samuel H. Wilson; Joseph Kraut
Maternal Rescue of Transforming Growth Factor-β1 Null Mice, pp. 1936-1938
John J. Letterio; Andrew G. Geiser; Ashok B. Kulkarni; Nanette S. Roche; Michael B. Sporn; Anita B. Roberts
Implications of FRA16A Structure for the Mechanism of Chromosomal Fragile Site Genesis, pp. 1938-1941
J. K. Nancarrow; E. Kremer; K. Holman; H. Eyre; N. A. Doggett; D. Le Paslier; D. F. Callen; G. R. Sutherland; R. I. Richards
Receptor and Ligand Domains for Invasion of Erythrocytes by Plasmodium falciparum, pp. 1941-1944
B. K. L. Sim; C. E. Chitnis; K. Wasniowska; T. J. Hadley; L. H. Miller
Structure of the RGD Protein Decorsin: Conserved Motif and Distinct Function in Leech Proteins That Affect Blood Clotting, pp. 1944-1947
Andrzej M. Krezel; Gerhard Wagner; Jana Seymour-Ulmer; Robert A. Lazarus
Sequestration of GPI-Anchored Proteins in Caveolae Triggered by Cross-Linking, pp. 1948-1951
Satyajit Mayor; Karen G. Rothberg; Frederick R. Maxfield


Book Reviews
A View of the Particle World, p. 1952
Conceptual Foundations of Modern Particle Physics.
Robert E. Marshak
Review author[s]: Chris Quigg
∼2.71828, pp. 1952-1953
e. The Story of a Number.
Eli Maor
Review author[s]: Peter Borwein
Mammalian Evolution, pp. 1953-1954
Morphological Change in Quaternary Mammals of North America.
Robert A. Martin; Anthony D. Barnosky
Review author[s]: Ernest L. Lundelius Jr.
How RNA Makes DNA, pp. 1954-1955
Reverse Transcriptase.
Anna Marie Skalka; Stephen P. Goff
Review author[s]: Robin A. Weiss
Books Received, p. 1955


Inside AAAS, pp. 1962-1965
Diana Pabst

Back Matter (27 pp.)

Previous Issue: New Series, Vol. 264, No. 5166, Jun. 17, 1994
Next Issue: New Series, Vol. 265, No. 5168, Jul. 1, 1994



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