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Science, New Series, Vol. 269, No. 5222, Jul. 21, 1995


Previous Issue: New Series, Vol. 269, No. 5221, Jul. 14, 1995
Next Issue: New Series, Vol. 269, No. 5223, Jul. 28, 1995


Front Matter (20 pp.)
Editorial: Big Questions for a Small Planet, p. 283
Richard B. Gallagher; Joshua Fischman; Pamela J. Hines


Letters
"Adaptive Mutation": The Debate Goes On, pp. 285-288
Richard E. Lenski; Paul D. Sniegowski; James A. Shapiro
Adaptive Mutation and Sex, p. 288
John Cairns; J. Pablo Radicella; Maurice S. Fox; Peter U. Park
Mutation Rate of the F Episome, pp. 288-289
François Taddei; Miroslav Radman; Jennifer A. Halliday; Tim Galitski; John Roth


ScienceScope, p. 291
Richard Stone


News and Comment
NIH Escapes the Ax -- For Now, pp. 292-293
Eliot Marshall
AIDS Research: Who Should Hold the Purse Strings?, p. 292
Jon Cohen
FDA Panel OKs Baboon Marrow Transplant, pp. 293-294
Elizabeth Pennisi
Final Rules Put Universities in Charge, p. 294
Jeffrey Mervis
Dana-Farber Death Sends a Warning to Research Hospitals, pp. 295-296
Wade Roush
China Meeting Signals New Commitment, p. 296
Ted Plafker
New Rules Push Researchers Closer to Biotech Industry, pp. 297-298
Ganapati Mudur
Joint Dioxin Research Imperiled, p. 298
Richard Stone


Research News
Pushing the Data Storage Envelope, pp. 299-300
Robert F. Service
How Quasars Make Heavy Metal, p. 300
James Glanz
Protein Proves to Be a Key Link in Innate Immunity, pp. 301-302
Clare Thompson
Plants Proving Their Worth in Toxic Metal Cleanup, pp. 302-303
Anne Simon Moffat
Chernobyl: Life Abounds Without People, p. 304
Nigel Williams
Portuguese Rock Art Gets Younger, p. 304
Joshua Fischman


Random Samples, pp. 305+307
Jocelyn Kaiser


Frontiers in Biology: Ecology


News
When Rigor Meets Reality, pp. 313-315
Wade Roush
Taking a New Look at Life Through a Functional Lens, pp. 316-317
Richard Stone
Filling In Florida's Gaps: Species Protection Done Right?, pp. 318-320
Charles C. Mann
Slow Start for Europe's New Habitat Protection Plan, pp. 320-322
Nigel Williams
In Hawaii, Taking Inventory of A Biological Hot Spot, pp. 322-323
Christine Mlot

Ecosystem Experiments, pp. 324-327
Stephen R. Carpenter; Sallie W. Chisholm; Charles J. Krebs; David W. Schindler; Richard F. Wright
Ecological Experiments with Model Systems, pp. 328-331
John H. Lawton
Landscape Ecology: Spatial Heterogeneity in Ecological Systems, pp. 331-334
S. T. A. Pickett; M. L. Cadenasso
Ecology and Climate: Research Strategies and Implications, pp. 334-341
Terry L. Root; Stephen H. Schneider
Population Growth and Earth's Human Carrying Capacity, pp. 341-346
Joel E. Cohen
The Future of Biodiversity, pp. 347-350
Stuart L. Pimm; Gareth J. Russell; John L. Gittleman; Thomas M. Brooks
Restoring Value to the World's Degraded Lands, pp. 350-354
Gretchen C. Daily
International Public Opinion on the Environment, pp. 354-358
David E. Bloom
Environmental Unknowns, pp. 358-360
Norman Myers


Perspectives
Biological Implications of the Middle Miocene Amazon Seaway, pp. 361-362
S. David Webb
Laminin β2 (S-Laminin): A New Player at the Synapse, pp. 362-363
Zach W. Hall
Obituary: John Marlie (1945-1995), p. 363


Research Article
Structurally Complex and Highly Active RNA Ligases Derived from Random RNA Sequences, pp. 364-370
Eric H. Ekland; Jack W. Szostak; David P. Bartel


Reports
Quantum Point Contact Switches, pp. 371-373
D. P. E. Smith
Ferroelectric Field Effect in Epitaxial Thin Film Oxide SrCuO2/Pb(Zr 0.52 Ti 0.48 )O3 Heterostructures, pp. 373-376
C. H. Ahn; J.-M. Triscone; N. Archibald; M. Decroux; R. H. Hammond; T. H. Geballe; Ø. Fischer; M. R. Beasley
Luminescence Enhancement by the Introduction of Disorder into Poly(p-phenylene vinylene), pp. 376-378
S. Son; A. Dodabalapur; A. J. Lovinger; M. E. Galvin
Cooling of Tropical Brazil (5°C) during the Last Glacial Maximum, pp. 379-383
M. Stute; M. Forster; H. Frischkorn; A. Serejo; J. F. Clark; P. Schlosser; W. S. Broecker; G. Bonani
Primitive Boron Isotope Composition of the Mantle, pp. 383-386
Marc Chaussidon; Bernard Marty
Late Miocene Tidal Deposits in the Amazonian Foreland Basin, pp. 386-390
Matti E. Räsänen; Ari M. Linna; José C. R. Santos; Francisco R. Negri
Female Responses to Ancestral Advertisement Calls in Túngara Frogs, pp. 390-392
Michael J. Ryan; A. Stanley Rand
First-Principles Calculation of the Folding Free Energy of a Three-Helix Bundle Protein, pp. 393-396
Erik M. Boczko; Charles L. Brooks III
Telomerase in Yeast, pp. 396-400
Marita Cohn; Elizabeth H. Blackburn
Simultaneous Identification of Bacterial Virulence Genes by Negative Selection, pp. 400-403
Michael Hensel; Jacqueline E. Shea; Colin Gleeson; Michael D. Jones; Emma Dalton; David W. Holden
Integration of MAP Kinase Signal Transduction Pathways at the Serum Response Element, pp. 403-407
Alan J. Whitmarsh; Paul Shore; Andrew D. Sharrocks; Roger J. Davis
Inactivation of the Mouse Huntington's Disease Gene Homolog Hdh, pp. 407-410
Mabel P. Duyao; Anna B. Auerbach; Angela Ryan; Francesca Persichetti; Glenn T. Barnes; Sandra M. McNeil; Pei Ge; Jean-Paul Vonsattel; James F. Gusella; Alexandra L. Joyner; Marcy E. MacDonald
Permeation Selectivity by Competition in a Delayed Rectifier Potassium Channel, pp. 410-412
Stephen J. Korn; Stephen R. Ikeda
A Synaptic Localization Domain in the Synaptic Cleft Protein Laminin β2 (s-Laminin), pp. 413-416
Paul T. Martin; Audrey J. Ettinger; Joshua R. Sanes


Technical Comments
Targeting Retroviral Vectors to Specific Cells, p. 417
David Kabat; Noriyuki Kasahara; Andrée Dozy; Yuet Wai Kan
Minimal Path Algorithms, p. 418
D. Gareth Williams; O. Steinbock; K. Showalter


Book Reviews
Ongoing Ecology, pp. 421-422
Long-Term Experiments in Agricultural and Ecological Sciences.
R. A. Leigh; A. E. Johnston
Review author[s]: Katherine L. Gross
Environmental Debate, pp. 422-423
Reinventing Nature? Responses to Postmodern Deconstruction.
Michael E. Soulé; Gary Lease
Review author[s]: Jeffrey Hearn
Books Received, p. 423


Back Matter (25 pp.)

Previous Issue: New Series, Vol. 269, No. 5221, Jul. 14, 1995
Next Issue: New Series, Vol. 269, No. 5223, Jul. 28, 1995



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