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Science, New Series, Vol. 254, No. 5028, Special Issue: Instrumentation, Oct. 4, 1991


Previous Issue: New Series, Vol. 253, No. 5027, Sep. 27, 1991
Next Issue: New Series, Vol. 254, No. 5029, Genome Issue: Maps and Database, Oct. 11, 1991


Front Matter (30 pp.)
Instrumentation, p. 9
John I. Brauman


Letters
Brain Tumor Incidence at Los Alamos, p. 11
S. S. Hecker
Peer Review and Patent Rights, p. 11
Barbara R. Greenberg
Volcanoes: How Dangerous?, p. 11
Danny J. Boggs


Correction: Isolation of a rel-Related Human cDNA That Potentially Encodes the 65-kD Subunit of NF-κB, p. 11
S. M. Ruben; P. J. Dillon; R. Schreck; T. Henkel; C.-H. Chen; M. Maher; P. A. Baeuerle; C. A. Rosen

ScienceScope, p. 19
David P. Hamilton


News and Comment
A Is for Apple, Alar, and...Alarmist?, pp. 20-22
Eliot Marshall
Free Speech and Clinical Trials, p. 23
Marcia Barinaga
Emphasizing the Health in NIH, pp. 23-24
Joseph Palca
Glenn Uncovers the Great Pizza Scandal, p. 24
Eliot Marshall
Reproductive Toxicity: Regs Slow to Change, p. 25
Ann Gibbons
East Germany: Science in the Disservice of the State, pp. 26-27
Steven Dickman


Briefings
Whistleblowing for Fun and Profit, p. 28
Constance Holden
The Hunt for Drugs From Nature, p. 28
Constance Holden
Creme de la Creme, p. 28
Constance Holden
GOES-NEXT to Wait Out Next Round, pp. 28-29
Constance Holden
U.S. Still Balks at Greenhouse Talks, p. 29
Constance Holden
No Quick Fixes for Learning, p. 29
Constance Holden
Water Couldn't Dash This BBQ, p. 29
Constance Holden


Research News
Doing Chemistry in the Round, pp. 30-31
Ivan Amato
A Long Look in the Extreme Ultraviolet, p. 32
Ken Croswell
A Hand on the Bird-And One on the Bush, pp. 33-34
Virginia Morell
Gamma-Ray Observatory: Bursting with New Results, pp. 34-35
Faye Flam
Transgenic Animals May Be Down on the Pharm, pp. 35-36
Anne Simon Moffat
A First Investment in a Kaon Factory, pp. 36-37
Faye Flam
Some Would KO KAON, p. 37
Douglas Powell


Echo-Planar Imaging: Magnetic Resonance Imaging in a Fraction of a Second, pp. 43-50
Michael K. Stehling; Robert Turner; Peter Mansfield

Determination of Macromolecular Structures from Anomalous Diffraction of Synchrotron Radiation, pp. 51-58
Wayne A. Hendrickson

Large-Scale and Automated DNA Sequence Determination, pp. 59-67
T. Hunkapiller; R. J. Kaiser; B. F. Koop; L. Hood

Chemical Imaging of Surfaces with the Scanning Electrochemical Microscope, pp. 68-74
Allen J. Bard; Fu-Ren F. Fan; David T. Pierce; Patrick R. Unwin; David O. Wipf; Feimeng Zhou

Chemical Microsensors, pp. 74-80
R. C. Hughes; A. J. Ricco; M. A. Butler; S. J. Martin


Research Article
Detection of Somatic DNA Recombination in the Transgenic Mouse Brain, pp. 81-86
Masao Matsuoka; Fumikiyo Nagawa; Kenji Okazaki; Linda Kingsbury; Kazuya Yoshida; Urs Müller; David T. Larue; Jeffery A. Winer; Hitoshi Sakano


Reports
Energy Transfer Between Two Peptides Bound to One MHC Class II Molecule, pp. 87-89
Robert Tampé; Brian R. Clark; Harden M. McConnell
Periodic Hot-Spot Distribution on Io, pp. 89-91
Atsushi Yamaji
Early Cretaceous Uplift in the Ellsworth Mountains of West Antarctica, pp. 92-94
Paul G. Fitzgerald; Edmund Stump
A Dominant Negative Form of Transcription Activator mTFE3 Created by Differential Splicing, pp. 94-97
Christopher Roman; Lauren Cohn; Kathryn Calame
A Mutation in the Amyloid Precursor Protein Associated with Hereditary Alzheimer's Disease, pp. 97-99
Jill Murrell; Martin Farlow; Bernardino Ghetti; Merrill D. Benson
Regulation of Transendothelial Neutrophil Migration by Endogenous Interleukin-8, pp. 99-102
Andreas R. Huber; Steven L. Kunkel; Robert F. Todd; Stephen J. Weiss
Suppression of the Immune Response by a Soluble Complement Receptor of B Lymphocytes, pp. 102-105
Thomas Hebell; Joseph M. Ahearn; Douglas T. Fearon
Neutralization of Divergent HIV-1 Isolates by Conformation-Dependent Human Antibodies to Gp120, pp. 105-108
Kathelyn S. Steimer; Carl J. Scandella; Paul V. Skiles; Nancy L. Haigwood
A Bacterial System for Investigating Transport Effects of Cystic Fibrosis- Associated Mutations, pp. 109-111
Amy L. Gibson; Lois M. Wagner; Francis S. Collins; Dale L. Oxender
Molecular Cloning of an Invertebrate Glutamate Receptor Subunit Expressed in Drosophila Muscle, pp. 112-114
Christoph M. Schuster; Andreas Ultsch; Patrick Schloss; Jane A. Cox; Bertram Schmitt; Heinrich Betz
Functional Modulation of Brain Sodium Channels by Protein Kinase C Phosphorylation, pp. 115-118
Randal Numann; William A. Catterall; Todd Scheuer
Establishment of the Mesoderm-Neuroectoderm Boundary in the Drosophila Embryo, pp. 118-122
David Kosman; Y. Tony Ip; Michael Levine; Kavita Arora


Technical Comment
Mathematical Analysis of a Model of the Mitotic Clock, pp. 122-123
C. D. Thron


Book Reviews
Thinking About Food, p. 133
Plants, Power, and Profit. Social, Economic, and Ethical Consequences of the New Biotechnologies.
Lawrence Busch; William B. Lacy; Jeffrey Burkhardt; Laura R. Lacy
Review author[s]: Robert J. Thomas
Delayed Cures, pp. 133-134
A Simple Matter of Salt. An Ethnography of Nutritional Deficiency in Spain.
Renate Lellep Fernandez
Review author[s]: Ann V. Millard
Evolutionary Disentanglement, pp. 134-136
The Comparative Method in Evolutionary Biology.
Paul H. Harvey; Mark D. Pagel
Review author[s]: Donald B. Miles


Back Matter (28 pp.)

Previous Issue: New Series, Vol. 253, No. 5027, Sep. 27, 1991
Next Issue: New Series, Vol. 254, No. 5029, Genome Issue: Maps and Database, Oct. 11, 1991



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