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Science, New Series, Vol. 262, No. 5140, Dec. 10, 1993


Previous Issue: New Series, Vol. 262, No. 5139, Dec. 3, 1993
Next Issue: New Series, Vol. 262, No. 5141, Dec. 17, 1993


Front Matter (43 pp.)
Editorial: Evolution of Scientific Research, p. 1627
Philip H. Abelson


Letters
Mind and Brain, p. 1629
Victor I. Reus; Daniel E. Koshland Jr.
Scientific Evidence and the Courts, pp. 1629-1631
Thomas G. Field Jr.; Michael D. Green; Rochelle Dreyfuss; Dorothy Nelkin
Transportation Costs, p. 1631
Frank J. Mandriota; Ellis Glazier
Idolizing Wolves, pp. 1631-1632
L. David Mech
Health Care and Life Expectancy, p. 1632
George H. Hitchings


Corrections and Clarifications: A World of Rock, p. 1632
ScienceScope, p. 1635
Richard Stone


News and Comment
At NSF: Fewer, Longer Grants, pp. 1636-1638
Jeffrey Mervis
Psychiatry Chair Ousted Amidst Schism at UCSF, pp. 1639-1640
Marcia Barinaga
German Blood Contamination Found Low, p. 1640
Peter Aldhous
Task Force to Speed Drug Pipeline, p. 1641
Jon Cohen
Failing to Cross the Biology-Culture Gap, pp. 1641-1642
Constance Holden
Expert Panel Criticizes Federal Activities, p. 1642
Jeffrey Mervis


Random Samples, p. 1643
Constance Holden


Research News
How p53 Suppresses Cell Growth, pp. 1644-1645
Jean Marx
Materials Science Comes to Life at Boston Gathering, pp. 1646-1647
John Travis
Can DNA Mimics Improve On the Real Thing?, pp. 1647-1649
Faye Flam
Pattern Emerges in Cosmic Ray Mystery, p. 1649
Gary Taubes


Policy Forum
The Future of the Fetal Tissue Bank, pp. 1663-1665
Cynthia B. Cohen; Albert R. Jonsen


Perspectives
The Deadly Latur Earthquake, pp. 1666-1667
Harsh K. Gupta
Cancer, Catenins, and Cuticle Pattern: A Complex Connection, pp. 1667-1668
Mark Peifer


Lipid Tubules: A Paradigm for Molecularly Engineered Structures, pp. 1669-1676
Joel M. Schnur

Biological Diversity, Soils, and Economics, pp. 1676-1680
Michael Huston


Research Article
Protein Design by Binary Patterning of Polar and Nonpolar Amino Acids, pp. 1680-1685
Satwik Kamtekar; Jarad M. Schiffer; Huayu Xiong; Jennifer M. Babik; Michael H. Hecht


Reports
Manipulating Chlorine Atom Bonding on the Si(100)-(2 × 1) Surface with the STM, pp. 1703-1706
John J. Boland
Attempts to Mimic Docking Processes of the Immune System: Recognition-Induced Formation of Protein Multilayers, pp. 1706-1708
W. Müller; H. Ringsdorf; E. Rump; G. Wildburg; X. Zhang; L. Angermaier; W. Knoll; M. Liley; J. Spinke
Inner Core Anisotropy Due to the Magnetic Field-Induced Preferred Orientation of Iron, pp. 1708-1711
Shun-ichiro Karato
Adhesive Electroless Metallization of Fluoropolymeric Substrates, pp. 1711-1712
Terrence G. Vargo; Joseph A. Gardella, Jr.; Jeffrey M. Calvert; Mu-San Chen
Translocation of Repetitive RNA Sequences with the Germ Plasm in Xenopus Oocytes, pp. 1712-1714
Malgorzata Kloc; Georges Spohr; Laurence D. Etkin
The Role of Backbone Flexibility in the Accommodation of Variants That Repack the Core of T4 Lysozyme, pp. 1715-1718
E. P. Baldwin; O. Hajiseyedjavadi; W. A. Baase; B. W. Matthews
Modulation of Calmodulin Plasticity in Molecular Recognition on the Basis of X-Ray Structures, pp. 1718-1721
William E. Meador; Anthony R. Means; Florante A. Quiocho
Restoration of HIV-Specific Cell-Mediated Immune Responses by Interleukin-12 in Vitro, pp. 1721-1724
Mario Clerici; Daniel R. Lucey; Jay A. Berzofsky; Ligia A. Pinto; Thomas A. Wynn; Stephen P. Blatt; Matthew J. Dolan; Craig W. Hendrix; Stanley F. Wolf; Gene M. Shearer
Dense Nonsymmetrical DNA Methylation Resulting from Repeat-Induced Point Mutation in Neurospora, pp. 1724-1728
Eric U. Selker; Deborah Y. Fritz; Michael J. Singer
Initiation at Closely Spaced Replication Origins in a Yeast Chromosome, pp. 1728-1731
Bonita J. Brewer; Walton L. Fangman
Association of the APC Gene Product with β-Catenin, pp. 1731-1734
Bonnee Rubinfeld; Brian Souza; Iris Albert; Oliver Müller; Scott H. Chamberlain; Frank R. Masiarz; Susan Munemitsu; Paul Polakis
Association of the APC Tumor Suppressor Protein with Catenins, pp. 1734-1737
Li-Kuo Su; Bert Vogelstein; Kenneth W. Kinzler
Abnormal Chromosome Behavior in Neurospora Mutants Defective in DNA Methylation, pp. 1737-1741
Henriette M. Foss; Christopher J. Roberts; Karen M. Claeys; Eric U. Selker
Elements of the Yeast Pheromone Response Pathway Required for Filamentous Growth of Diploids, pp. 1741-1744
Haoping Liu; Cora Ann Styles; Gerald R. Fink
Mutations That Allow Disulfide Bond Formation in the Cytoplasm of Escherichia coli, pp. 1744-1747
Alan I. Derman; William A. Prinz; Dominique Belin; Jon Beckwith
The Learning of Categories: Parallel Brain Systems for Item Memory and Category Knowledge, pp. 1747-1749
Barbara J. Knowlton; Larry R. Squire


Book Reviews
The Matter of Tobacco Use, pp. 1750-1751
Smoking Policy. Law, Politics, and Culture.
Robert L. Rabin; Stephen D. Sugarman
Review author[s]: Philip J. Cook
Culture in the Paleolithic, pp. 1751-1752
Before Lascaux. The Complex Record of the Early Upper Paleolithic.
Heidi Knecht; Anne Pike-Tay; Randall White
Review author[s]: Richard G. Klein
New World Representations, pp. 1752-1754
Picturing Nature. American Nineteenth-Century Zoological Illustration.
Ann Shelby Blum
Review author[s]: William Stanton
Books Received, p. 1754


Back Matter (34 pp.)

Previous Issue: New Series, Vol. 262, No. 5139, Dec. 3, 1993
Next Issue: New Series, Vol. 262, No. 5141, Dec. 17, 1993



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