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Science, New Series, Vol. 262, No. 5130, Genome Issue, Oct. 1, 1993


Previous Issue: New Series, Vol. 261, No. 5129, Sep. 24, 1993
Next Issue: New Series, Vol. 262, No. 5131, Oct. 8, 1993


Front Matter (30 pp.)
Editorial: Pushing at the Envelope, p. 11
Barbara R. Jasny


Letters
Synchroton X-Rays from a B Factory, p. 13
Boris W. Batterman; Donald H. Bilderback; Karl Berkelman
Biodiversity Entreaty, pp. 13-14
John E. Tobin; Rebecca Goldburg; D. Douglas Hopkins
Science and Restoration, pp. 14-15
Roger C. Anderson; Edith B. Allen; M. Rebecca Anderson; James S. Fralish; R. Michael Miller; William A. Niering
The Chlorine Controversy, pp. 15-16
Gary M. Williams; T. S. Benedict Yen


Corrections and Clarifications: Cornell Leads Battle of the B Factories, p. 16
Corrections and Clarifications: Potassium Selectivity in Proteins: Oxygen Cage or π in the Face?, p. 16
ScienceScope, p. 19
Richard Stone


News and Comment
Taking Stock of the Genome Project, pp. 20-22
Leslie Roberts
Michigan Gets an Expensive Lesson, p. 23
Christopher Anderson
NIH Told to Reconsider Crime Meeting, pp. 23-24
Eliot Marshall
Young Scientists' Network Shakes Up the Establishment, pp. 24-25
David H. Freedman
Peer Review Goes Under the Microscope, pp. 25-26
Gary Taubes


Research News
Pleistocene Population Explosions, pp. 27-28
Ann Gibbons
A First Step Toward Gene Therapy for Hemophilia B?, pp. 29-30
Jean Marx
Are Dark Stars the Silent Majority?, pp. 30-31
Faye Flam
High-Tc Superconductors Get Squeezed, p. 31
Ivan Amato
Hope for a Magic Bullet That Moves at the Speed of Light, pp. 32-33
Ivan Amato
Galileo Reveals a Badly Battered Ida, p. 33
Richard A. Kerr


Random Samples, pp. 34-35
Constance Holden


Genomes


Policy Forum
A New Five-Year Plan for the U.S. Human Genome Project, pp. 43-46
Francis Collins; David Galas


Perspectives
Managing All Those Bytes: The Human Genome Project, pp. 47-48
A. Jamie Cuticchia; Michael A. Chipperfield; Christopher J. Porter; William Kearns; Peter L. Pearson
Presymptomatic Diagnosis: A First Step Toward Genetic Health Care, pp. 48-49
C. Thomas Caskey

A Genetic Linkage Map of the Mouse: Current Applications and Future Prospects, pp. 57-66
Neal G. Copeland; Nancy A. Jenkins; Debra J. Gilbert; Janan T. Eppig; Lois J. Maltais; Joyce C. Miller; William F. Dietrich; Alix Weaver; Stephen E. Lincoln; Robert G. Steen; Lincoln D. Stein; Joseph H. Nadeau; Eric S. Lander


Genome
Genome Map IV. The Mouse, pp. 67-82
Neal G. Copeland; Debra J. Gilbert; Nancy A. Jenkins; Joseph H. Nadeau; Janan T. Eppig; Lois J. Maltais; Joyce C. Miller; William F Dietrich; Robert G. Steen; Stephen E. Lincoln; Alix Weaver; Diane C. Joyce; Mark Merchant; Michael Wessel; Hillary Katz; Lincoln D. Stein; Mary Pat Reeve; Mark J. Daly; Robert D. Dredge; Andre Marquis; Nathan Goodman; Eric S. Lander


Reports
Inclined-Field Structure, Morphology, and Pinning of the Vortex Lattice in Microtwinned YBa2Cu3O7, pp. 83-86
B. Keimer; F. Doğan; I. A. Aksay; R. W. Erwin; J. W. Lynn; M. Sarikaya
Anatomy of the Photodissociation Region in the Orion Bar, pp. 86-89
A. G. G. M. Tielens; M. M. Meixner; P. P. van der Werf; J. Bregman; J. A. Tauber; J. Stutzki; D. Rank
Protein Ladder Sequencing, pp. 89-92
Brian T. Chait; Rong Wang; Ronald C. Beavis; Stephen B. H. Kent
Early Cambrian Ostracode Larvae with a Univalved Carapace, pp. 93-94
Xi-guang Zhang; Brian R. Pratt
Deep and Bottom Water of the Weddell Sea's Western Rim, pp. 95-97
Arnold L. Gordon; Bruce A. Huber; Hartmut H. Hellmer; Amy Ffield
Pressure-Induced Enhancement of Tc Above 150 K in Hg-1223, pp. 97-99
M. Nuñez-Regueiro; J.-L. Tholence; E. V. Antipov; J.-J. Capponi; M. Marezio
Protein Enhancement of Hammerhead Ribozyme Catalysis, pp. 99-102
Zenta Tsuchihashi; Mala Khosla; Daniel Herschlag
Interaction of Mammalian Splicing Factor SF3a with U2 snRNP and Relation of Its 60-kD Subunit to Yeast PRP9, pp. 102-105
Reto Brosi; Karsten Gröning; Sven-Erik Behrens; Reinhard Lührmann; Angela Krämer
Correspondence Between a Mammalian Spliceosome Component and an Essential Yeast Splicing Factor, pp. 105-108
Maria Bennett; Robin Reed
Interaction Between PRP11 and SPP91 Yeast Splicing Factors and Characterization of a PRP9-PRP11-SPP91 Complex, pp. 108-110
Pierre Legrain; Christine Chapon
Ordered Restriction Maps of Saccharomyces cerevisiae Chromosomes Constructed by Optical Mapping, pp. 110-114
David C. Schwartz; Xiaojun Li; Luis I. Hernandez; Satyadarshan P. Ramnarain; Edward J. Huff; Yu-Ker Wang
Erythrocyte P Antigen: Cellular Receptor for B19 Parvovirus, pp. 114-117
Kevin E. Brown; Stacie M. Anderson; Neal S. Young
In Vivo Gene Therapy of Hemophilia B: Sustained Partial Correction in Factor IX-Deficient Dogs, pp. 117-119
Mark A. Kay; Steven Rothenberg; Charles N. Landen; Dwight A. Bellinger; Frances Leland; Carol Toman; Milton Finegold; Arthur R. Thompson; M. S. Read; Kenneth M. Brinkhous; Savio L. C. Woo


Book Reviews
Hot Neologisms, pp. 121-122
The Uses of Life. A History of Biotechnology.
Robert Bud
Review author[s]: Glenn E. Bugos
Post-Gradualism, pp. 122-123
The New Catastrophism. The Importance of the Rare Event in Geological History.
Derek Ager
Review author[s]: Warren D. Allmon
The Birth of Stars, pp. 123-124
Star Formation in Stellar Systems.
G. Tenorio-Tagle; M. Prieto; F. Sánchez
Review author[s]: John S. Gallagher III
Worthy Animals, p. 124
A Functional Biology of Parasitism. Ecological and Evolutionary Implications.
Gerald W. Esch; Jacqueline C. Fernández
Review author[s]: Janice Moore
----------------, pp. 124-125
Centennial History of the Geological Society of Washington, 1893-1993.
Eugene C. Robertson
Review author[s]: Katherine Livingston
----------------, p. 125
Frontiers of Science. Reports from the Final International Session of the Moscow Refusnik Seminar.
Yuri B. Chernyak; Joel L. Lebowitz
Review author[s]: Katherine Livingston
Books Received, p. 125


Back Matter (23 pp.)

Previous Issue: New Series, Vol. 261, No. 5129, Sep. 24, 1993
Next Issue: New Series, Vol. 262, No. 5131, Oct. 8, 1993



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