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Science, New Series, Vol. 265, No. 5177, Sep. 2, 1994


Previous Issue: New Series, Vol. 265, No. 5176, Aug. 26, 1994
Next Issue: New Series, Vol. 265, No. 5178, Sep. 9, 1994


Front Matter (18 pp.)
Editorial: Vaccines: A Study in Contrasts, p. 1343
Paula A. Kiberstis; John M. Benditt; Daniel E. Koshland Jr.


Letters
Embryo Research Guidelines, p. 1345
Harold Varmus
Primates and New Viruses, pp. 1345-1346
Jonathan S. Allan
The Sobering D2 Story, pp. 1346-1347
Kenneth Blum; Ernest P. Noble; Constance Holden
Machine-Written Summary: Missed Opportunity?, p. 1348
Norman R. Olsen
Correction: Ferricyanide and Pattern Formation, p. 1348
Kyoung-Jin Lee; William D. McCormick; Qi Ouyang; Harry L. Swinney


Corrections and Clarifications: Pulling Hair from the Ground, p. 1348
Corrections and Clarifications: Orphan Chimps Won't Go Back to Nature, p. 1348
ScienceScope, p. 1351
Richard Stone


News and Comment
Forensic DNA Goes to Court With O.J., pp. 1352-1354
Rachel Nowak
German Lab Points the Way In Hunt for 'Hot' Plutonium, pp. 1355-1356
Richard Stone
Scopes and Squirrels Return to Court, p. 1356
John Travis
Bromley Memoirs Take Off the Gloves, p. 1357
Jeffrey Mervis
Buckyballs and Kin Are Still on a Roll, p. 1357
Jocelyn Kaiser


Random Samples, pp. 1358-1359
Constance Holden


Research News
The Solar System's New Diversity, pp. 1360-1362
Richard A. Kerr
Micro-Quasars Found in Our Galaxy, pp. 1362-1363
Ray Jayawardhana
Making Molecular Filters More Reactive, p. 1363
Robert F. Service
Link to Hereditary Melanoma Brightens Mood for p16 Gene, pp. 1364-1365
Jean Marx
Alzheimer's: Could There Be a Zinc Link?, p. 1365
Jocelyn Kaiser


Frontiers In Medicine: Vaccines


News Reports
Bumps on the Vaccine Road, pp. 1371-1373
Jon Cohen
Are Researchers Racing Toward Success, or Crawling?, pp. 1373-1375
Jon Cohen
U.S. National Program is Going Nowhere Fast, pp. 1375-1376
Rachel Nowak
Childrens' Vaccine Initiative Stumbles, pp. 1376-1377
Ann Gibbons


Policy Forum
The United States Needs a National Vaccine Authority, pp. 1378-1380
Barry R. Bloom


Perspectives
Malaria Vaccines: Multiple Targets, pp. 1381-1383
Ruth S. Nussenzweig; Carole A. Long
Vaccines for Varicella-Zoster Virus and Cytomegalovirus: Recent Progress, pp. 1383-1385
Stanley A. Plotkin
Pneumococcal Disease: Prospects for a New Generation of Vaccines, pp. 1385-1387
George R. Siber
Cholera Vaccines: Fighting an Ancient Scourge, pp. 1387-1389
John J. Mekalanos; Jerald C. Sadoff
Rotavirus Vaccines: Success by Reassortment?, pp. 1389-1391
Roger I. Glass; Jon Gentsch; Jean C. Smith
Measles Vaccine: Do We Need New Vaccines or New Programs?, pp. 1391-1392
Samuel L. Katz; Bruce G. Gellin
Prospects for a Respiratory Syncytial Virus Vaccine, pp. 1393-1394
Caroline Breese Hall
Lymphocyte Life-Span and Memory, pp. 1395-1400
Jonathan Sprent; David F. Tough

Vaccine Technologies: View to the Future, pp. 1401-1404
N. Regina Rabinovich; Pamela McInnes; David L. Klein; B. Fenton Hall


Research Article
Structures of Active Conformations of G iα1 and the Mechanism of GTP Hydrolysis, pp. 1405-1412
David E. Coleman; Albert M. Berghuis; Ethan Lee; Maurine E. Linder; Alfred G. Gilman; Stephen R. Sprang


Reports
Molecular Recognition by Self-Assembled Monolayers of Cavitand Receptors, pp. 1413-1415
K. D. Schierbaum; T. Weiss; E. U. Thoden van Velzen; J. F. J. Engbersen; D. N. Reinhoudt; W. Göpel
Nanocatalysis by the Tip of a Scanning Tunneling Microscope Operating Inside a Reactor Cell, pp. 1415-1418
B. J. McIntyre; M. Salmeron; G. A. Somorjai
A Redox Fuel Cell That Operates with Methane as Fuel at 120°C, pp. 1418-1420
Steven H. Bergens; Christopher B. Gorman; G. Tayhas R. Palmore; George M. Whitesides
A Spectroscopic Measurement of the Coronal Density of Procyon, pp. 1420-1422
J. H. M. M. Schmitt; B. M. Haisch; J. J. Drake
Morphology and Ionization of the Interstellar Cloud Surrounding the Solar System, pp. 1423-1427
Priscilla C. Frisch
Chemical Sequence Control of β-Sheet Assembly in Macromolecular Crystals of Periodic Polypeptides, pp. 1427-1432
Mark T. Krejchi; Edward D. T. Atkins; Alan J. Waddon; Maurille J. Fournier; Thomas L. Mason; David A. Tirrell
Stress Triggering of the 1994 M = 6.7 Northridge, California, Earthquake by Its Predecessors, pp. 1432-1435
Ross S. Stein; Geoffrey C. P. King; Jian Lin
Seismic Evidence for a Lower-Crustal Detachment Beneath San Francisco Bay, California, pp. 1436-1439
Thomas M. Brocher; Jill McCarthy; Patrick E. Hart; W. Steven Holbrook; Kevin P. Furlong; Thomas V. McEvilly; John A. Hole; Simon L. Klemperer
Redistribution of Intracellular Ca 2+ Stores During Phagocytosis in Human Neutrophils, pp. 1439-1441
Olle Stendahl; Karl-Heinz Krause; Joachim Krischer; Petra Jerström; Jean-Marc Theler; Robert A. Clark; Jean-Louis Carpentier; Daniel P. Lew
Ku80: Product of the XRCC5 Gene and Its Role in DNA Repair and V(D)J Recombination, pp. 1442-1445
Guillermo E. Taccioli; Tanya M. Gottlieb; Tracy Blunt; Anne Priestley; Jocelyne Demengeot; Ryushin Mizuta; Alan R. Lehmann; Frederick W. Alt; Stephen P. Jackson; Penny A. Jeggo
Thrombocytopenia in c-mpl-Deficient Mice, pp. 1445-1447
Austin L. Gurney; Karen Carver-Moore; Frederic J. de Sauvage; Mark W. Moore
Engineering Poliovirus as a Vaccine Vector for the Expression of Diverse Antigens, pp. 1448-1451
Raul Andino; Deborah Silvera; Shelley D. Suggett; Philip L. Achacoso; Christopher J. Miller; David Baltimore; Mark B. Feinberg
Prophylactic Vaccines, Risk Behavior Change, and the Probability of Eradicating HIV in San Francisco, pp. 1451-1454
S. M. Blower; A. R. McLean
Degradation of Gα by the N-End Rule Pathway, pp. 1454-1458
Kiran Madura; Alexander Varshavsky
Ras-Dependent Growth Factor Regulation of MEK Kinase in PC12 Cells, pp. 1458-1461
Carol A. Lange-Carter; Gary L. Johnson
Genetics of a Pheromonal Difference Contributing to Reproductive Isolation in Drosophila, pp. 1461-1464
Jerry A. Coyne; Anne P. Crittenden; Katherine Mah
Rapid Induction of Alzheimer Aβ Amyloid Formation by Zinc, pp. 1464-1467
Ashley I. Bush; Warren H. Pettingell; Gerd Multhaup; Marc d. Paradis; Jean-Paul Vonsattel; James F. Gusella; Konrad Beyreuther; Colin L. Masters; Rudolph E. Tanzi


Book Reviews
Owen as Strategist, pp. 1468-1469
Richard Owen. Victorian Naturalist.
Nicolaas A. Rupke
Review author[s]: Camille Limoges
Parasites on the Move, pp. 1469-1470
Evolution of Infectious Diseases.
Paul W. Ewald
Review author[s]: J. J. Bull; Bruce R. Levin
Planetary Surface Studies, pp. 1470-1471
Remote Geochemical Analysis. Elemental and Mineralogical Composition.
Carle M. Peters; Peter A. J. Englert
Review author[s]: Bruce M. Jakosky
Books Received, p. 1471


Back Matter (25 pp.)

Previous Issue: New Series, Vol. 265, No. 5176, Aug. 26, 1994
Next Issue: New Series, Vol. 265, No. 5178, Sep. 9, 1994



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