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Science, New Series, Vol. 260, No. 5116, Jun. 25, 1993


Previous Issue: New Series, Vol. 260, No. 5115, Jun. 18, 1993
Next Issue: New Series, Vol. 261, No. 5117, Jul. 2, 1993


Volume Information (10 pp.)
Front Matter (33 pp.)
Editorial: Pathological Growth of Regulations, p. 1859
Philip H. Abelson


Letters
Speaking Out, p. 1861
Carl Sagan; Edward O. Wilson; Daniel E. Koshland, Jr.
The LIGO Controversy, p. 1862
Charles F. Kennel
A Competitive Education, pp. 1862-1863
Arnold Grobman
The Science and Policy of Risk, p. 1863
Daniel M. Kammen; Richard Wilson


ScienceScope, p. 1867
Richard Stone


News and Comment
The High Cost of Biodiversity, pp. 1868-1871
Charles C. Mann; Mark L. Plummer
Academy Recommends Global Yardstick, p. 1871
Jeffrey Mervis
Scripps Backs Down on Controversial Sandoz Deal, pp. 1872-1873
Christopher Anderson
Clinton Backs SSC, Space Station, p. 1873
Eliot Marshall


Research News
Physicists Explore the Driplines, pp. 1874-1876
Gary Taubes
Making Modular Memories, p. 1876
Robert F. Service
Novel Anticancer Agents Move Closer to Reality, pp. 1877-1878
John Travis
Astronomers Watch the Stars Come Out in Berkeley, pp. 1878-1879
Faye Flam


Random Samples, pp. 1880-1881
Constance Holden


Environment and the Economy
Protecting the Environment with the Power of the Market, pp. 1884-1885
Joe Alper
Is Environmental Technology a Key to a Healthy Economy?, pp. 1886-1888
Eliot Marshall
A New Life for a National Clean Technology Workshop, pp. 1889-1890
Ivan Amato
Wetlands Trading is a Loser's Game, Say Ecologists, pp. 1890-1892
Leslie Roberts
Can Sustainable Farming Win the Battle of the Bottom Line?, pp. 1893-1895
Bob Holmes
How to Make the Forests of the World Pay Their Way, pp. 1895-1896
Joe Alper


Policy Forums
A Second Environmental Science: Human-Environment Interactions, pp. 1897-1899
Paul C. Stern
Biodiversity and Biotechnology, pp. 1900-1901
Dan L. Burk; Kenneth Barovsky; Gladys H. Monroy


Perspectives
Chaperones: Helpers Along the Pathways to Protein Folding, pp. 1902-1903
Elizabeth A. Craig
To Fold or Not to Fold..., pp. 1903-1904
David A. Agard


Tropical Deforestation and Habitat Fragmentation in the Amazon: Satellite Data from 1978 to 1988, pp. 1905-1910
David Skole; Compton Tucker


Research Article
Arrestin Function in Inactivation of G Protein-Coupled Receptor Rhodopsin in Vivo, pp. 1910-1916
Patrick J. Dolph; Rama Ranganathan; Nansi J. Colley; Robert W. Hardy; Michael Socolich; Charles S. Zuker


Reports
Crystal Structure of a Silyl Cation with No Coordination to Anion and Distant Coordination to Solvent, pp. 1917-1918
Joseph B. Lambert; Shizhong Zhang; Charlotte L. Stern; John C. Huffman
Optically Active Carbon: Kinetic Resolution of C 76 by Asymmetric Osmylation, pp. 1918-1920
Joel M. Hawkins; Axel Meyer
Evidence from Western North America for Rapid Shifts in Climate During the Last Glacial Maximum, pp. 1920-1923
Bruce D. Allen; Roger Y. Anderson
Spatiotemporal Patterns in the Energy Release of Great Earthquakes, pp. 1923-1926
Barbara Romanowicz
Arabidopsis thaliana DNA Methylation Mutants, pp. 1926-1928
Aurawan Vongs; Tetsuji Kakutani; Robert A. Martienssen; Eric J. Richards
A Mechanism for Virilization of Female Spotted Hyenas in Utero, pp. 1929-1931
Tamer M. Yalcinkaya; Pentti K. Siiteri; Jean-Louis Vigne; Paul Licht; Sushama Pavgi; Laurence G. Frank; Stephen E. Glickman
The Role of TH1 and TH2 Cells in a Rodent Malaria Infection, pp. 1931-1934
Andrew W. Taylor-Robinson; R. Stephen Phillips; Alison Severn; Salvador Moncada; Foo Y. Liew
Selective Inhibition of ras-Dependent Transformation by a Farnesyltransferase Inhibitor, pp. 1934-1937
Nancy E. Kohl; Scott D. Mosser; S. Jane deSolms; Elizabeth A. Giuliani; David L. Pompliano; Samuel L. Graham; Robert L. Smith; Edward M. Scolnick; Allen Oliff; Jackson B. Gibbs
Benzodiazepine Peptidomimetics: Potent Inhibitors of Ras Farnesylation in Animal Cells, pp. 1937-1942
Guy L. James; Joseph L. Goldstein; Michael S. Brown; Thomas E. Rawson; Todd C. Somers; Robert S. McDowell; Craig W. Crowley; Brian K. Lucas; Arthur D. Levinson; James C. Marsters, Jr.
Induction of Type I Diabetes by Interferon-α in Transgenic Mice, pp. 1942-1946
T. A. Stewart; B. Hultgren; X. Huang; S. Pitts-Meek; J. Hully; N. J. MacLachlan
Nitric Oxide and Carbon Monoxide Produce Activity-Dependent Long-Term Synaptic Enhancement in Hippocampus, pp. 1946-1950
Min Zhuo; Scott A. Small; Eric R. Kandel; Robert D. Hawkins
Binding of the Ras Activator Son of Sevenless to Insulin Receptor Substrate-1 Signaling Complexes, pp. 1950-1952
Kurt Baltensperger; Lynn M. Kozma; Andrew D. Cherniack; Jes K. Klarlund; Anil Chawla; Utpal Banerjee; Michael P. Czech
The Function of GRB2 in Linking the Insulin Receptor to Ras Signaling Pathways, pp. 1953-1955
E. Y. Skolnik; A. Batzer; N. Li; C.-H. Lee; E. Lowenstein; M. Mohammadi; B. Margolis; J. Schlessinger
Dissociation of Object and Spatial Processing Domains in Primate Prefrontal Cortex, pp. 1955-1958
Fraser A. W. Wilson; Séamas P. Ó Scalaidhe; Patricia S. Goldman-Rakic


Technical Comments
Unusual Mutational Mechanisms and Evolution, pp. 1958-1960
Paul Rainey; Richard Moxon; David A. Watson; Laurence D. Hurst; Alan Grafen; Richard E. Lenski; John E. Mittler
Evidence of Genetic Heterogeneity in the Long QT Syndrome, pp. 1960-1962
Jesaia Benhorin; Yoram M. Kalman; Aharon Medina; Jeffrey Towbin; Naama Rave-Harel; Thomas D. Dyer; John Blangero; Jean W. MacCluer; Bat sheva Kerem; Mark Keating


Inside AAAS, pp. 1963-1965
Karen Hopkin


Book Reviews
Perspectives on Royalty, pp. 1983-1984
Biology and Conservation of the Monarch Butterfly.
Stephen B. Malcolm; Myron P. Zalucki
Review author[s]: Arthur M. Shapiro
The Neuroglia Mystery, pp. 1984-1985
Astrocytes. Pharmacology and Function.
Sean Murphy
Review author[s]: George G. Somjen
Crystallography Explained, pp. 1985-1986
Fundamentals of Crystallography.
C. Giacovazzo
Review author[s]: William Bassett
Theoretical Physics, p. 1986
Quantum Field Theory.
Lowell S. Brown
Review author[s]: Pierre Ramond
Books Received, p. 1986


Back Matter (28 pp.)

Previous Issue: New Series, Vol. 260, No. 5115, Jun. 18, 1993
Next Issue: New Series, Vol. 261, No. 5117, Jul. 2, 1993



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