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Science, New Series, Vol. 264, No. 5157, Apr. 15, 1994


Previous Issue: New Series, Vol. 264, No. 5156, Apr. 8, 1994
Next Issue: New Series, Vol. 264, No. 5158, Apr. 22, 1994


Front Matter (28 pp.)
Editorial: The Biological Warfare of the Future, p. 327
Daniel E. Koshland Jr.


Letters
Ice Age "Venuses", p. 329
Alexander Marshack; L. R. Caswell
The Meaning of Models, pp. 329-331
John D. Sterman; Edward J. Rykiel Jr.; Naomi Oreskes; Kenneth Belitz; Kristin Shrader-Frechette


Corrections and Clarifications: Venuses Reappear, p. 331
ScienceScope, p. 335
Richard Stone


News and Comment
Livermore Faces Forces of Change, pp. 336-338
Christopher Anderson
Rising Yen Threatens Key Cancer Study, p. 338
Eliot Marshall
ATOC Delayed as Report Laments Research Gaps, pp. 339-340
Karen Schmidt
Disparities Detailed in NCI Division, p. 340
Lisa Seachrist
'Secretary Snafu' May Cost Researchers, Universities, p. 341
Jon Cohen


Random Samples, pp. 342-343
Constance Holden


Research News
New Tumor Suppressor May Rival p53, pp. 344-345
Jean Marx
A Supergiant Dies in the Whirlpool, p. 345
Ray Jayawardhana
The Keck Scopes Out the Legacy of the Big Bang, p. 346
Ray Jayawardhana
Alaska Sites Contend as Native Americans' First Stop, p. 347
Lisa Busch
New Instruments Shed Light On Astronomy's Future, pp. 348-349
John Travis
Anthropologists Take the Measure of Humanity, pp. 350-351
Ann Gibbons


Frontiers in Biotechnology: Resistance to Antibiotics
[Introduction], p. 359
Gilbert J. Chin; Jean Marx


News Reports
Reviving the Antibiotic Miracle?, pp. 360-362
John Travis
Funding Crunch Hobbles Antibiotic Resistance Research, pp. 362-363
Elizabeth Culotta
Resistance a European Problem, Too, pp. 363+364-365
Sharon Kingman
Hungary Sees an Improvement in Penicillin Resistance, p. 364
Rachel Nowak
Search for Sepsis Drugs Goes On Despite Past Failures, pp. 365-367
Richard Stone


Policy Forum
Infectious Disease Surveillance: A Crumbling Foundation, pp. 368-370
Ruth L. Berkelman; Ralph T. Bryan; Michael T. Osterholm; James W. LeDuc; James M. Hughes


Perspectives
Human Mycoses: Drugs and Targets for Emerging Pathogens, pp. 371-373
Nafsika H. Georgopapadakou; Thomas J. Walsh
Ubiquitous Natural Antibiotics, pp. 373-374
Joelle E. Gabay

Inactivation of Antibiotics and the Dissemination of Resistance Genes, pp. 375-382
Julian Davies
Prevention of Drug Access to Bacterial Targets: Permeability Barriers and Active Efflux, pp. 382-388
Hiroshi Nikaido
Resistance to Antibiotics Mediated by Target Alterations, pp. 388-393
Brian G. Spratt


Reports
Synthesis, Isolation, and Equilibration of 1,9- and 7,8-C 70 H2, pp. 397-399
Craig C. Henderson; Celeste McMichael Rohlfing; Kenneth T. Gillen; Paul A. Cahill
A Mass Spectrometric Solution to the Address Problem of Combinatorial Libraries, pp. 399-402
Christopher L. Brummel; Irene N. W. Lee; Ying Zhou; Stephen J. Benkovic; Nicholas Winograd
Antiferromagnetic Ordering and Paramagnetic Behavior of Ferromagnetic Cu6 and Cu 18 Clusters in BaCuO 2+x, pp. 402-404
Z.-R. Wang; X.-L. Wang; J. A. Fernandez-Baca; D. C. Johnston; D. Vaknin
Temperatures in Earth's Core Based on Melting and Phase Transformation Experiments on Iron, pp. 405-407
S. K. Saxena; G. Shen; P. Lazor
Topographic Forcing of the Atmosphere and a Rapid Change in the Length of Day, pp. 407-409
David A. Salstein; Richard D. Rosen
Anisotropy and Coherent Vortex Structures in Planetary Turbulence, pp. 410-413
James C. McWilliams; Jeffrey B. Weiss; Irad Yavneh
Thousandfold Change in Resistivity in Magnetoresistive La-Ca-Mn-O Films, pp. 413-415
S. Jin; T. H. Tiefel; M. McCormack; R. A. Fastnacht; R. Ramesh; L. H. Chen
Adhesion Forces Between Individual Ligand-Receptor Pairs, pp. 415-417
Ernst-Ludwig Florin; Vincent T. Moy; Hermann E. Gaub
Structure of the Tet Repressor-Tetracycline Complex and Regulation of Antibiotic Resistance, pp. 418-420
Winfried Hinrichs; Caroline Kisker; Martina Düvel; Alexander Müller; Karlheinz Tovar; Wolfgang Hillen; Wolfram Saenger
Stomatal Size in Fossil Plants: Evidence for Polyploidy in Majority of Angiosperms, pp. 421-424
Jane Masterson
Differential Complementation of Bcr-Abl Point Mutants with c-Myc, pp. 424-426
Daniel E. H. Afar; Andrei Goga; Jami McLaughlin; Owen N. Witte; Charles L. Sawyers
A Dual Embryonic Origin for Vertebrate Mechanoreceptors, pp. 426-430
Andres Collazo; Scott E. Fraser; Paula M. Mabee
Association of Intestinal Peptide Transport with a Protein Related to the Cadherin Superfamily, pp. 430-433
Anne H. Dantzig; JoAnn Hoskins; Linda B. Tabas; Stuart Bright; Robert L. Shepard; Ivan L. Jenkins; Dale C. Duckworth; J. Richard Sportsman; Daniel Mackensen; Paul R. Rosteck, Jr.; Paul L. Skatrud
Association of Poly(CA)·Poly(TG) DNA Fragments Into Four-Stranded Complexes Bound by HMG1 and 2, pp. 433-436
Claire Gaillard; François Strauss
A Cell Cycle Regulator Potentially Involved in Genesis of Many Tumor Types, pp. 436-440
Alexander Kamb; Nelleke A. Gruis; Jane Weaver-Feldhaus; Qingyun Liu; Keith Harshman; Sean V. Tavtigian; Elisabeth Stockert; Rufus S. Day III; Bruce E. Johnson; Mark H. Skolnick


Book Reviews
Fly Culture, pp. 445-446
Lords of the Fly. Drosophila Genetics and Experimental Practice.
Robert E. Kohler
Review author[s]: Philip J. Pauly
Fatal Disharmonies, pp. 446-447
The Ghost of the Executed Engineer. Technology and the Fall of the Soviet Union.
Loren R. Graham
Review author[s]: David Holloway
A Theory of Perception, pp. 447-448
Information, Sensation, and Perception.
Kenneth H. Norwich
Review author[s]: John C. Baird
"Organic Technology", p. 448
Molecular Nonlinear Optics. Materials, Physics, and Devices.
Joseph Zyss
Review author[s]: Nicolaas Bloembergen
Books Received, pp. 448-449


Back Matter (27 pp.)

Previous Issue: New Series, Vol. 264, No. 5156, Apr. 8, 1994
Next Issue: New Series, Vol. 264, No. 5158, Apr. 22, 1994



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