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Science, New Series, Vol. 260, No. 5110, May 14, 1993


Previous Issue: New Series, Vol. 260, No. 5109, May 7, 1993
Next Issue: New Series, Vol. 260, No. 5111, May 21, 1993


Front Matter (35 pp.)
Editorial: The Human Cornucopia, p. 875
Barbara R. Jasny; Linda J. Miller


Letters
"MegaYAC" Library, p. 877
Glen A. Evans
Interdisciplinary Symposia, p. 877
Ben Zuckerman
Funding for Gene Therapy, pp. 877-878
Bruce A. Chabner; Ronald Levy
Biosphere 2: A New Kind of Science, pp. 878-879
Eugene P. Odum
Judging Science, p. 879
Jay A. Gold; Miles J. Zaremski; Elaine Rappaport Lev; Deborah H. Shefrin; Shanna H. Swan
Multidrug Resistance-Associated Protein: Sequence Correction, p. 879
Susan P. C. Cole; Roger G. Deeley
Knowing It All, p. 879
Ronald N. Bracewell


Corrections and Clarifications: Keystone's Blunt Message: 'It's the Virus Stupid', p. 879


Policy Forum
The Stalemate in Food and Agricultural Research, Teaching, and Extension, pp. 881+1007
James H. Meyer


ScienceScope, p. 883
Richard Stone


News and Comment
Measure for Measure in Science, pp. 884-886
Gary Taubes
Research Community Swats Grasshopper Control Trial, p. 887
Billy Goodman
Glossy Strategic Plan Hits the Streets, p. 888
Jon Cohen
Task Force: Level the Playing Field, pp. 888-889
Traci Watson
Yet Another Science Minister for Germany, p. 889
Peter Aldhous


Research News
How Ice Age Climate Got the Shakes, pp. 890-892
Richard A. Kerr
Old Feuds, New Finds Mark Anthropologists' Meeting, pp. 892-893
Elizabeth Culotta
The Remembrance of Blinks Past, p. 894
Marcia Barinaga
Botanical Witness for the Prosecution, pp. 894-895
Carol Kaesuk Yoon
Pons and Fleischmann Redux?, p. 895
Ivan Amato


Random Samples, pp. 896-897
Constance Holden


Frontiers in Biotechnology


News Reports
Biotech Gets a Grip on Cell Adhesion, pp. 906-908
John Travis
Biotech Sails Into Heavy Financial Seas, pp. 908-910
Richard Stone
Going Back to the Future With Small Synthetic Compounds, pp. 910-912
Anne Simon Moffat
Stand and Deliver: Getting Peptide Drugs Into the Body, pp. 912-913
Brigid M. Wallace; Jill S. Lasker
New Startups Move in As Gene Therapy Goes Commercial, pp. 914-915
Elizabeth Culotta


Perspectives
Molecular Advances in Cardiovascular Biology, pp. 916-917
Kenneth R. Chien
New Intracellular Targets for Therapeutic Drug Design, pp. 918-919
Joan S. Brugge

Tissue Engineering, pp. 920-926
Robert Langer; Joseph P. Vacanti
The Basic Science of Gene Therapy, pp. 926-932
Richard C. Mulligan
New Challenges in Human in Vitro Fertilization, pp. 932-936
Robert M. L. Winston; Alan H. Handyside
Identifying Strategies for Immune Intervention, pp. 937-944
Antonio Lanzavecchia


Research Article
Regulation of V(D)J Recombination Activator Protein RAG-2 by Phosphorylation, pp. 953-959
Weei-Chin Lin; Stephen Desiderio


Reports
Potassium Channels in Samanea saman Protoplasts Controlled by Phytochrome and the Biological Clock, pp. 960-962
Hak Yong Kim; Gary G. Coté; Richard C. Crain
A Large Drop in Atmospheric 14 C/ 12 C and Reduced Melting in the Younger Dryas, Documented with 230 Th Ages of Corals, pp. 962-968
R. Lawrence Edwards; J. Warren Beck; G. S. Burr; D. J. Donahue; J. M. A. Chappell; A. L. Bloom; E. R. M. Druffel; F. W. Taylor
Beach Cusps as Self-Organized Patterns, pp. 968-971
B. T. Werner; T. M. Fink
Geography of End-Cretaceous Marine Bivalve Extinctions, pp. 971-973
David M. Raup; David Jablonski
Interaction of the San Jacinto and San Andreas Fault Zones, Southern California: Triggered Earthquake Migration and Coupled Recurrence Intervals, pp. 973-976
Christopher O. Sanders
Detection of HIV-1 DNA and Messenger RNA in Individual Cells by PCR-Driven in Situ Hybridization and Flow Cytometry, pp. 976-979
Bruce K. Patterson; Michele Till; Patricia Otto; Charles Goolsby; Manohar R. Furtado; Lincoln J. McBride; Steven M. Wolinsky
Crystal Structure of Domains 3 and 4 of Rat CD4: Relation to the NH2-Terminal Domains, pp. 979-983
R. L. Brady; E. J. Dodson; G. G. Dodson; G. Lange; S. J. Davis; A. F. Williams; A. N. Barclay
Sequestration from Immune CD4+ T Cells of Mycobacteria Growing in Human Macrophages, pp. 984-986
Preeti Pancholi; Asra Mirza; Nina Bhardwaj; Ralph M. Steinman
CD19 of B Cells as a Surrogate Kinase Insert Region to Bind Phosphatidylinositol 3-Kinase, pp. 986-989
David A. Tuveson; Robert H. Carter; Stephen P. Soltoff; Douglas T. Fearon
Localization of a Memory Trace in the Mammalian Brain, pp. 989-991
David J. Krupa; Judith K. Thompson; Richard F. Thompson
Induction of Gα i2 -Specific Antisense RNA in Vivo Inhibits Neonatal Growth, pp. 991-995
Christopher M. Moxham; Yaacov Hod; Craig C. Malbon
Cue-Invariant Shape Selectivity of Macaque Inferior Temporal Neurons, pp. 995-997
Gyula Sáry; Rufin Vogels; Guy A. Orban
Induction of Olfactory Receptor Sensitivity in Mice, pp. 998-1000
Hai-Wei Wang; Charles J. Wysocki; Geoffrey H. Gold


Book Reviews
Paycheck Equity, pp. 1008-1009
Comparable Worth. Theories and Evidence.
Paula England
Review author[s]: Joan Acker
Human Auxology, pp. 1009-1010
Growth, Maturation, and Body Composition. The Fels Longitudinal Study, 1929-1991.
Alex F. Roche
Review author[s]: Robert M. Malina
Looking at Crystals, pp. 1010-1011
Macromolecular Crystallography with Synchrotron Radiation.
John R. Helliwell
Review author[s]: Jenny P. Glusker
Anatomical Beginnings, p. 1011
Morphogenesis. An Analysis of the Development of Biological Form.
Edward F. Rossomando; Stephen Alexander
Review author[s]: Peter B. Armstrong
Books Received, pp. 1011-1012


Back Matter (32 pp.)

Previous Issue: New Series, Vol. 260, No. 5109, May 7, 1993
Next Issue: New Series, Vol. 260, No. 5111, May 21, 1993



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