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Science, New Series, Vol. 263, No. 5150, Feb. 25, 1994


Previous Issue: New Series, Vol. 263, No. 5149, Feb. 18, 1994
Next Issue: New Series, Vol. 263, No. 5151, Mar. 4, 1994


Front Matter (22 pp.)
Editorial: Strategic Goals on an NIH Model, p. 1071
Daniel E. Koshland, Jr.


Letters
Animal Rights and Radical Politics, pp. 1073-1075
Adrian R. Morrison; Harold Herzog
Pork Barrel Funding an Embarrassment, pp. 1075-1076
George E. Laramore; Christopher Anderson
Safety in Quarks?, p. 1076
Arnold Kramish


Corrections and Clarifications: Cure of Xenografted Human Carcinomas by BR96-Doxorubicin Immunoconjugates, p. 1076
Corrections and Clarifications: Gene Future: The Promise and Perils of the New Biology, p. 1076
ScienceScope, p. 1079
Richard Stone


News and Comment
Measuring What Works in Health Care, pp. 1080+1082
Christopher Anderson
Academic Medicine's Stake in Health Care Reform, p. 1081
Eliot Marshall
Russia Seen Poised to Drop Prosecution of Chemist, pp. 1083-1084
Richard Stone
Losing Friends and Influencing Policy, p. 1084
Jon Cohen
Lane Holds to the Middle in Debate Over NSF's Future, pp. 1085-1086
Jeffrey Mervis
Phosphorus Fingered as Coral Killer, p. 1086
Maria Burke


Research News
Rewriting-and Redating-Prehistory, pp. 1087-1088
Ann Gibbons
A Glimmer of Hope for Coastal Migration, pp. 1088-1089
Lisa Busch
Iron Fertilization: A Tonic, but No Cure for the Greenhouse, pp. 1089-1090
Richard A. Kerr
Theoretical Ecology: Winning Its Spurs in the Real World, pp. 1090-1092
Anne Simon Moffat
Atom Beams Split by Gentle Persuasion, p. 1092
Robert Pool
Researchers Find New Role for Cell Cycle Proteins, p. 1093
Jean Marx


Random Samples, pp. 1094-1095
Constance Holden


Perspectives
Thinking About Prozac, pp. 1102-1103
Samuel H. Barondes
Duality of TBP, the Universal Transcription Factor, pp. 1103-1104
Kevin Struhl


Trench-Parallel Flow Beneath the Nazca Plate from Seismic Anisotropy, pp. 1105-1111
R. M. Russo; P. G. Silver


Reports
Spatially Resolved Observation of Static Magnetic Flux States in YBa2Cu3O 7-δ Grain Boundary Josephson Junctions, pp. 1112-1114
G. M. Fischer; B. Mayer; R. Gross; T. Nissel; K.-D. Husemann; R. P. Huebener; T. Freltoft; Y. Shen; P. Vase
Making Ceramics "Ductile", pp. 1114-1116
Brian R. Lawn; Nitin P. Padture; Hongda Cai; Fernando Guiberteau
Double Seismic Zone for Deep Earthquakes in the Izu-Bonin Subduction Zone, pp. 1116-1118
Takashi Iidaka; Yoshitsugu Furukawa
Age of the Earliest Known Hominids in Java, Indonesia, pp. 1118-1121
C. C. Swisher; G. H. Curtis; T. Jacob; A. G. Getty; A. Suprijo; Widiasmoro
A Molecular Organic Carbon Isotope Record of Miocene Climate Changes, pp. 1122-1125
M. Schoell; S. Schouten; J. S. Sinninghe Damsté; J. W. de Leeuw; R. E. Summons
Deep, Zonal Subequatorial Currents, pp. 1125-1128
Lynne D. Talley; Gregory C. Johnson
Extension of Life-Span by Overexpression of Superoxide Dismutase and Catalase in Drosophila melanogaster, pp. 1128-1130
William C. Orr; Rajindar S. Sohal
Requirement for CD8 β Chain in Positive Selection of CD8-Lineage T Cells, pp. 1131-1133
Kei-ichi Nakayama; Keiko Nakayama; Izumi Negishi; Keisuke Kuida; Marjorie C. Louie; Osami Kanagawa; Hiromitsu Nakauchi; Dennis Y. Loh
Persistence of Transients in Spatially Structured Ecological Models, pp. 1133-1136
Alan Hastings; Kevin Higgins
Sequential Interactions of the TCR with Two Distinct Cytoplasmic Tyrosine Kinases, pp. 1136-1139
Makio Iwashima; Bryan A. Irving; Nicolai S. C. van Oers; Andrew C. Chan; Arthur Weiss
T Cell Deletion in High Antigen Dose Therapy of Autoimmune Encephalomyelitis, pp. 1139-1143
Jeffrey M. Critchfield; Michael K. Racke; Juan Carlos Zúñiga-Pflücker; Barbara Cannella; Cedric S. Raine; Joan Goverman; Michael J. Lenardo
Premature p34 cdc2 Activation Required for Apoptosis, pp. 1143-1145
Lianfa Shi; Walter K. Nishioka; John Th'ng; E. Morton Bradbury; David W. Litchfield; Arnold H. Greenberg
Protein-Protein Interactions Contributing to the Specificity of Intracellular Vesicular Trafficking, pp. 1146-1149
Nicole Calakos; Mark K. Bennett; Karen E. Peterson; Richard H. Scheller
Replacement of Diseased Mouse Liver by Hepatic Cell Transplantation, pp. 1149-1152
Jonathan A. Rhim; Eric P. Sandgren; Jay L. Degen; Richard D. Palmiter; Ralph L. Brinster
Phosphorylation of the Transcription Factor PHO4 by a Cyclin-CDK Complex, PHO80-PHO85, pp. 1153-1156
Arie Kaffman; Ira Herskowitz; Robert Tjian; Erin K. O'Shea


Technical Comments
Gene Flow or Heterozygote Advantage?, pp. 1157-1158
David Berrigan; Jay Evans; David Holway; Lucia Jacobs; Miriam Richards; Jon Seger; Laurent Keller; Kenneth G. Ross; D. K. Schwartz; R. Viswanathan; J. A. Zasadzinski
Examining Langmuir-Blodgett Films with Atomic Force Microscopy, pp. 1158-1159
L. Bourdieu; O. Ronsin; D. Chatenay


Book Reviews
Widespread Likings, pp. 1161-1162
The Biophilia Hypothesis.
Stephen R. Kellert; Edward O. Wilson
Review author[s]: Claude S. Fischer
Atomic Science, pp. 1162-1163
Critical Assembly. A Technical History of Los Alamos During the Oppenheimer Years, 1943-1945.
Lillian Hoddeson; Paul W. Henriksen; Roger A. Meade; Catherine Westfall; Gordon Baym
Review author[s]: Rudolf Peierls
Protecting Plants, pp. 1163-1164
Biotechnology in Plant Disease Control.
Ilan Chet
Review author[s]: Neal K. Van Alfen
Growth and Division, pp. 1164-1165
The Cell Cycle. An Introduction.
Andrew Murray; Tim Hunt
Review author[s]: Frederick R. Cross; Kristi Levine
Books Received, p. 1165


Inside AAAS, pp. 1168-1169
Diana Pabst

Back Matter (23 pp.)

Previous Issue: New Series, Vol. 263, No. 5149, Feb. 18, 1994
Next Issue: New Series, Vol. 263, No. 5151, Mar. 4, 1994



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