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Science, New Series, Vol. 250, No. 4988, Dec. 21, 1990


Previous Issue: New Series, Vol. 250, No. 4987, Dec. 14, 1990
Next Issue: New Series, Vol. 251, No. 4989, Jan. 4, 1991


Volume Information (10 pp.)
Front Matter (14 pp.)
The Molecular of the Year, p. 1637
Daniel E. Koshland, Jr.

Diamond: Glittering Prize for Materials Science, pp. 1640-1643
Ruth Levy Guyer; Daniel E. Koshland, Jr.


Letters
Carcinogens and Human Health: Part 1, pp. 1644-1646
Frederica P. Perera; Bruce N. Ames; Lois S. Gold
The Avocado Illusion, p. 1646
Paul E. Sandorff


Erratum: Biology Goes to the Movies, p. 1646
Erratum: Mapping Terra Incognita (Humani Corporis), p. 1646


News and Comment
Choosing Detectors for the SSC, pp. 1648-1650
Robert Crease
Stanford Sails Into a Storm, p. 1651
Marcia Barinaga
A Rare View of the Moon, p. 1651
Richard Kerr
Biomedical Funding: The Eternal "Crisis", pp. 1652-1653
Barbara J. Culliton
Space Program: Blueprint for Ambiguity?, p. 1654
David Hamilton


Research News
Slow Going for Blood Substitutes, pp. 1655-1656
Robert Pool
Immune Mystery Revealed: How MHC Meets Antigen, pp. 1657-1658
Marcia Barinaga
Astro-1: From the Jaws of Defeat, p. 1658
Ann Gibbons
Breast Cancer: Two Steps Closer to Understanding, p. 1659
Karen Wright
Volcanoes: Old, New, and-Perhaps-Yet to Be, pp. 1660-1661
Richard A. Kerr


Briefings
NSF Watchdog Plays Up Misconduct, p. 1662
David P. Hamilton
Gazing Through a Gravitational Lens, p. 1662
David P. Hamilton
Natchez Man Gets Younger, p. 1662
David P. Hamilton
What Next for the Energy Labs?, pp. 1662-1663
David P. Hamilton
Brown Ousts Staffer from Committee, p. 1663
David P. Hamilton
Pinning Down Sequencing Costs, p. 1663
David P. Hamilton
GAO Finds Weapons Labs Vulnerable..., p. 1663
David P. Hamilton
Ulysses: All Shook Up, p. 1663
David P. Hamilton


A Mechanism for Social Selection and Successful Altruism, pp. 1665-1668
Herbert A. Simon

Biomass Burning in the Tropics: Impact on Atmospheric Chemistry and Biogeochemical Cycles, pp. 1669-1678
Paul J. Crutzen; Meinrat O. Andreae

Mechanisms in the Cycle of Violence, pp. 1678-1683
Kenneth A. Dodge; John E. Bates; Gregory S. Pettit


Research Articles
Linkage of Early-Onset Familial Breast Cancer to Chromosome 17q21, pp. 1684-1689
Jeff M. Hall; Ming K. Lee; Beth Newman; Jan E. Morrow; Lee A. Anderson; Bing Huey; Mary-Claire King
Cloning and Expression of a Developmentally Regulated Protein that Induces Mitogenic and Neurite Outgrowth Activity, pp. 1690-1694
Yue-Sheng Li; Peter G. Milner; Anil K. Chauhan; Mark A. Watson; Ruth M. Hoffman; Charles M. Kodner; Jeffrey Milbrandt; Thomas F. Deuel
Targeting the E1 Replication Protein to the Papillomavirus Origin of Replication by Complex Formation with the E2 Transactivator, pp. 1694-1699
Ian J. Mohr; Robin Clark; Shaw Sun; Elliot J. Androphy; Paul MacPherson; Michael R. Botchan


Reports
Iridium Profile for 10 Million Years Across the Cretaceous-Tertiary Boundary at Gubbio (Italy), pp. 1700-1702
Walter Alvarez; Frank Asaro; Alessandro Montanari
Kinematics of Late Paleozoic Continental Collision Between Laurentia and Gondwana, pp. 1702-1705
Paul E. Sacks; Donald T. Secor, Jr.
Control of a Desert-Grassland Transition by a Keystone Rodent Guild, pp. 1705-1707
James H. Brown; Edward J. Heske
Characterization of "Peak E," a Novel Amino Acid Associated with Eosinophilia-Myalgia Syndrome, pp. 1707-1708
Arthur N. Mayeno; Feng Lin; Christopher S. Foote; David A. Loegering; Matthew M. Ames; Craig W. Hedberg; Gerald J. Gleich
Zinc Mediation of the Binding of Human Growth Hormone to the Human Prolactin Receptor, pp. 1709-1712
Brian C. Cunningham; Steven Bass; Germaine Fuh; James A. Wells
Stable, Monomeric Variants of λ Cro Obtained by Insertion of a Designed β-Hairpin Sequence, pp. 1712-1715
Michael C. Mossing; Robert T. Sauer
Inheritance of Proliferative Breast Disease in Breast Cancer Kindreds, pp. 1715-1720
Mark H. Skolnick; Lisa A. Cannon-Albright; David E. Goldgar; John H. Ward; C. Jay Marshall; G. Berry Schumann; Hugh Hogle; William P. McWhorter; Eileen C. Wright; Thao D. Tran; D. Timothy Bishop; James P. Kushner; Harmon J. Eyre
Induction by Antigen of Intrathymic Apoptosis of CD4+CD8+ TCR lo Thymocytes in Vivo, pp. 1720-1723
Kenneth M. Murphy; Amy B. Heimberger; Dennis Y. Loh
Transport Protein Genes in the Murine MHC: Possible Implications for Antigen Processing, pp. 1723-1726
John J. Monaco; Sungae Cho; Michelle Attaya
Peripheral Clonal Elimination of Functional T Cells, pp. 1726-1729
Lori A. Jones; L. Thomas Chin; Dan L. Longo; Ada M. Kruisbeek
Hemolin: An Insect-Immune Protein Belonging to the Immunoglobulin Superfamily, pp. 1729-1732
Shao-Cong Sun; Ingrid Lindström; Hans G. Boman; Ingrid Faye; Otto Schmidt
Dominant Negative Regulation of the Mouse α-Fetoprotein Gene in Adult Liver, pp. 1732-1735
Jean Vacher; Shirley M. Tilghman
Calcium-Sensitive Inactivation in the Gating of Single Calcium Channels, pp. 1735-1738
David T. Yue; Peter H. Backx; John P. Imredy
A New Arbovirus from Aedes albopictus, an Asian Mosquito Established in the United States, pp. 1738-1740
D. B. Francy; N. Karabatsos; D. M. Wesson; C. G. Moore, Jr.; J. S. Lazuick; M. L. Niebylski; T. F. Tsai; G. B. Craig, Jr.
Regulation of Progesterone Receptor-Mediated Transcription by Phosphorylation, pp. 1740-1743
Larry A. Denner; Nancy L. Weigel; Beth L. Maxwell; William T. Schrader; Bert W. O'Malley
Early Enhancement of Calcium Currents by H-ras Oncoproteins Injected into Hermissenda Neurons, pp. 1743-1745
Carlos Collin; Alex G. Papageorge; Douglas R. Lowy; Daniel L. Alkon
Hot Spots for Growth Hormone Gene Deletions in Homologous Regions Outside of Alu Repeats, pp. 1745-1748
Cindy L. Vnencak-Jones; John A. Phillips III


Technical Comments
Type 1 Neurofibromatosis Gene: Correction, p. 1749
Margaret R. Wallace; Douglas A. Marchuk; Lone B. Andersen; Francis S. Collins; Gary R. Skuse


Inside AAAS, pp. 1750-1753
Cynthia Lollar


Book Reviews
Head Starts, pp. 1754-1755
The High-Status Track. Studies of Elite Schools and Stratification.
Paul William Kingston; Lionel S. Lewis
Review author[s]: David Karen
The Two-Year Colleges, pp. 1755-1756
The Diverted Dream. Community Colleges and the Promise of Educational Opportunity in America, 1900-1985.
Steven Brint; Jerome Karabel
Review author[s]: Harold S. Wechsler
Cosmic Ray Days, pp. 1756-1757
Moments in the Life of a Scientist.
Bruno Rossi
Review author[s]: Michael W. Friedlander
Kinetostatics, pp. 1757-1758
Freedom in Machinery. Vol. 2, Screw Theory Exemplified.
Jack Phillips
Review author[s]: Joseph Duffy; Michael Griffis
The Universe Updated, p. 1758
The Astronomer's Universe. Stars, Galaxies, and Cosmos.
Herbert Friedman
Review author[s]: Katherine Bracher
Earthquakes, pp. 1758-1759
The Mechanics of Earthquakes and Faulting.
Christopher H. Scholz
Review author[s]: Ronald L. Bruhn
Books Received, p. 1759


Back Matter (29 pp.)

Previous Issue: New Series, Vol. 250, No. 4987, Dec. 14, 1990
Next Issue: New Series, Vol. 251, No. 4989, Jan. 4, 1991



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