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Science, New Series, Vol. 261, No. 5117, Jul. 2, 1993


Previous Issue: New Series, Vol. 260, No. 5116, Jun. 25, 1993
Next Issue: New Series, Vol. 261, No. 5118, Jul. 9, 1993


Front Matter (12 pp.)
Editorial: Simplicity and Complexity in Conflict of Interest, p. 11
Daniel E. Koshland, Jr.


Letters
DNA Evidence, p. 13
Rockne P. Harmon
Dioxin's Effects, p. 13
Ulf G. Ahlborg
Alvin and Deep Ocean Research, pp. 13-14
Paul J. Fox; Craig E. Dorman
The Future of IBM Research, p. 14
David D. Awschalom
Strangers in the Woodpile, pp. 14-15
W. J. Mathey; Marvin T. Smith
A Path Not Taken, p. 15
Dorothy Odell Teasley


Corrections and Clarifications: New Altzheimer's Therapy Suggested, p. 15


Policy Forums
NIH Funding Mechanisms Need Appraisal, pp. 16+112
Donald D. Brown
NIH Funding Mechanisms Need Little Defense, pp. 17+113
Lawrence M. Lichtenstein


ScienceScope, p. 19
Richard Stone


News and Comment
Donna Shalala and the Future of NIH, pp. 20-21
Jeffrey Mervis
Supreme Court to Judges: Start Thinking Like Scientists, p. 22
Jeffrey Mervis
Strategic Plan Meets the Bureaucracy, p. 23
Jon Cohen
Universities on Alert After Bomb Attacks, pp. 23-24
Christopher Anderson
Joining Forces to Probe Environment-Health Links, pp. 24-25
Michael Balter


Random Samples, pp. 26-27
Christopher Anderson


Research News
The Life History of Galaxy Clusters, pp. 28-30
Ann Finkbeiner
Nocturnal Researchers Tune Their Ears to Our Ancestors, pp. 30-31
Elizabeth Culotta
Satellite Data Rocket Disease Control Efforts Into Orbit, pp. 31-32
Marcia Barinaga
Fermat's Last Theorem Finally Yields, pp. 32-33
Barry Cipra


Perspectives
Foreign Invaders, pp. 34-35
Joel W. Hedgpeth
Molecular Muscle, pp. 35-36
Edwin W. Taylor


Achieving Acceptable Air Quality: Some Reflections on Controlling Vehicle Emissions, pp. 37-45
J. G. Calvert; J. B. Heywood; R. F. Sawyer; J. H. Seinfeld

Geophysical Investigations of the Tectonic Boundary Between East and West Antarctica, pp. 45-50
U. S. ten Brink; S. Bannister; B. C. Beaudoin; T. A. Stern


Research Articles
Three-Dimensional Structure of Myosin Subfragment-1: A Molecular Motor, pp. 50-58
Ivan Rayment; Wojciech R. Rypniewski; Karen Schmidt-Bäse; Robert Smith; Diana R. Tomchick; Matthew M. Benning; Donald A. Winkelmann; Gary Wesenberg; Hazel M. Holden
Structure of the Actin-Myosin Complex and Its Implications for Muscle Contraction, pp. 58-65
Ivan Rayment; Hazel M. Holden; Michael Whittaker; Christopher B. Yohn; Michael Lorenz; Kenneth C. Holmes; Ronald A. Milligan


Reports
Diamonds, Eclogites, and the Oxidation State of the Earth's Mantle, pp. 66-68
Robert W. Luth
Paleozoic Atmospheric CO2: Importance of Solar Radiation and Plant Evolution, pp. 68-70
Robert A. Berner
Detection of Interstellar Pick-Up Hydrogen in the Solar System, pp. 70-73
G. Gloeckler; J. Geiss; H. Balsiger; L. A. Fisk; A. B. Galvin; F. M. Ipavich; K. W. Ogilvie; R. von Steiger; B. Wilken
Directionally Aligned Helical Peptides on Surfaces, pp. 73-76
James K. Whitesell; Hye Kyung Chang
Quantification of the Influence of Surface Structure on C-H Bond Activation by Iridium and Platinum, pp. 76-78
Dale F. Johnson; W. Henry Weinberg
Ecological Roulette: The Global Transport of Nonindigenous Marine Organisms, pp. 78-82
James T. Carlton; Jonathan B. Geller
Regulation of Lymphoid-Specific Immunoglobulin μ Heavy Chain Gene Enhancer by ETS-Domain Proteins, pp. 82-86
Barbara Nelsen; Gang Tian; Batu Erman; Jacqueline Gregoire; Richard Maki; Barbara Graves; Ranjan Sen
Increased Activity of L-Type Ca 2+ Channels Exposed to Serum from Patients with Type I Diabetes, pp. 86-90
Lisa Juntti-Berggren; Olof Larsson; Patrik Rorsman; Carina Ämmälä; Krister Bokvist; Karin Wåhlander; Pierluigi Nicotera; Jeanette Dypbukt; Sten Orrenius; Anders Hallberg; Per-Olof Berggren
Resistance of MHC Class I-Deficient Mice to Experimental Systemic Lupus Erythematosus, pp. 91-93
Edna Mozes; Leonard D. Kohn; Fran Hakim; Dinah S. Singer
Interleukin-7: A Cofactor for V(D)J Rearrangement of the T Cell Receptor β Gene, pp. 93-95
K. Muegge; M. P. Vila; S. K. Durum
Chemorepulsion of Axons in the Developing Mammalian Central Nervous System, pp. 95-98
Adrian Pini
A Processing Stream in Mammalian Visual Cortex Neurons for Non-Fourier Responses, pp. 98-101
Yi-Xiong Zhou; Curtis L. Baker, Jr.
G Protein-Coupled Signal Transduction Pathways for Interleukin-8, pp. 101-103
Dianqing Wu; Gregory J. LaRosa; Melvin I. Simon
Enhancement by Histamine of NMDA-Mediated Synaptic Transmission in the Hippocampus, pp. 104-106
John M. Bekkers
A Transglutaminase that Converts Interleukin-2 into a Factor Cytotoxic to Oligodendrocytes, pp. 106-108
Shoshana Eitan; Michal Schwartz
Commitment of Cell Fate in the Early Zebrafish Embryo, pp. 109-111
Robert K. Ho; Charles B. Kimmel


Book Reviews
A Giant in Geochemistry, pp. 114-115
Victor Moritz Goldschmidt. Father of Modern Geochemistry.
Brian Mason
Review author[s]: Lawrence Grossman
From Plant to Planet, pp. 115-117
Scaling Physiological Processes. Leaf to Globe.
James R. Ehleringer; Christopher B. Field
Review author[s]: Thomas J. Givnish
The Binary Zoo, p. 117
The Realm of Interacting Binary Stars.
J. Sahade; G. E. McCluskey, Jr.; Y. Kondo
Review author[s]: Richard H. Durisen
NMR for Beginners, pp. 117-118
Fundamentals of Nuclear Magnetic Resonance.
Jacek W. Hennel; Jacek Klinowski
Review author[s]: Neil S. Sullivan
Books Received, p. 118


Back Matter (14 pp.)

Previous Issue: New Series, Vol. 260, No. 5116, Jun. 25, 1993
Next Issue: New Series, Vol. 261, No. 5118, Jul. 9, 1993



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