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Science, New Series, Vol. 251, No. 4989, Jan. 4, 1991


Previous Issue: New Series, Vol. 250, No. 4988, Dec. 21, 1990
Next Issue: New Series, Vol. 251, No. 4990, Jan. 11, 1991


Front Matter (17 pp.)
New Year's Resolutions and Future Shock, p. 9
Daniel E. Koshland, Jr.


Letters
Carcinogens and Human Health: Part 2, pp. 10-13
David P. Rall; Bruce N. Ames; Lois S. Gold
Cold Spring Harbor, p. 13
John Cairns


Erratum: Biology Goes to the Movies, p. 13
Erratum: Broadly Neutralizing Antibodies Elicited by the Hypervariable Neutralizing Determinant of HIV-1, p. 13


News and Comment
NSF Centers Rise Above the Storm, pp. 19-22
Joseph Palca
Fight Over Data Disrupts Michigan State Project, pp. 23-24
Eliot Marshall
SSC Detectors: Yes, No, Maybe, p. 24
Robert Crease
Research Papers: Who's Uncited Now?, p. 25
David P. Hamilton
Leroy Hood Says No, p. 25
Leslie Roberts
Will Canada Build on Earlier TRIUMF?, p. 26
Douglas Powell


Briefings
Rehabilitation for Burt?, p. 27
Constance Holden
Science Money Woes in the U.S.S.R., p. 27
Constance Holden
NASA's Wish List, p. 27
Constance Holden


Research News
Making 3-D Movies of the Heart, pp. 28-30
Robert Pool
Cosmologists Begin to Fill in the Blanks, pp. 30-31
M. Mitchell Waldrop
On the Road to Mandelate...Racemase, pp. 31-32
Michelle Hoffman


Perspective
Mechanisms of Alternative Pre-mRNA Splicing, pp. 33-34
Tom Maniatis


Free Radicals Within the Antarctic Vortex: The Role of CFCs in Antarctic Ozone Loss, pp. 39-46
J. G. Anderson; D. W. Toohey; W. H. Brune

The Dynamics of the Stratospheric Polar Vortex and Its Relation to Springtime Ozone Depletions, pp. 46-52
Mark R. Schoeberl; Dennis L. Hartmann

Spot-Scan Imaging in Transmission Electron Microscopy, pp. 53-59
Kenneth H. Downing


Research Article
Atomic Structure of Ferredoxin-NADP$^ $ Reductase: Prototype for a Structurally Novel Flavoenzyme Family, pp. 60-66
P. Andrew Karplus; Mark J. Daniels; Jon R. Herriott


Reports
Observational Evidence for a Possible New Diffusion Path, pp. 67-70
Bradley R. Hacker; John M. Christie
Long-Term Human B Cell Lines Dependent on Interleukin-4 and Antibody to CD40, pp. 70-72
Jacques Banchereau; Paolo De Paoli; Alain Vallé; Eric Garcia; Françoise Rousset
Expression cDNA Cloning of the KGF Receptor by Creation of a Transforming Autocrine Loop, pp. 72-75
Toru Miki; Timothy P. Fleming; Donald P. Bottaro; Jeffrey S. Rubin; Dina Ron; Stuart A. Aaronson
Generation of Calcium Oscillations in Fibroblasts by Positive Feedback Between Calcium and IP3, pp. 75-78
Alec T. Harootunian; Joseph P. Y. Kao; Suman Paranjape; Roger Y. Tsien
Glycosylphosphatidylinositol: A Candidate System for Interleukin-2 Signal Transduction, pp. 78-81
Diane D. Eardley; Marian Elliott Koshland
Whole Animal Cell Sorting of Drosophila Embryos, pp. 81-85
Mark A. Krasnow; Susan Cumberledge; Gerard Manning; Leonard A. Herzenberg; Garry P. Nolan
Inhibition of Morphine Tolerance and Dependence by the NMDA Receptor Antagonist MK-801, pp. 85-87
Keith A. Trujillo; Huda Akil
Critical Structural Elements of the VP16 Transcriptional Activation Domain, pp. 87-90
W. Douglas Cress; Steven J. Triezenberg
Three-Dimensional Structures of Acidic and Basic Fibroblast Growth Factors, pp. 90-93
X. Zhu; H. Komiya; A. Chirino; S. Faham; G. M. Fox; T. Arakawa; B. T. Hsu; D. C. Rees


Technical Comments
Model Simulation of Mid-Cretaceous Ocean Circulation, pp. 94-95
Karl B. Föllmi; M. Delamette; Eric J. Barron; William H. Peterson


Book Reviews
A Case for Listening, pp. 96-97
Making Connections. The Relational Worlds of Adolescent Girls at Emma Willard School.
Carol Gilligan; Nona P. Lyons; Trudy J. Hanmer
Review author[s]: Naomi Gerstel
Condensed Matter, pp. 97-98
The Superfluid Phases of Helium 3.
Dieter Vollhardt; Peter Wölfle
Review author[s]: Joseph W. Serene
Calamar, p. 98
Squid as Experimental Animals.
Daniel L. Gilbert; William J. Adelman, Jr.; John M. Arnold
Review author[s]: William F. Gilly
Books Received, p. 98


Back Matter (34 pp.)

Previous Issue: New Series, Vol. 250, No. 4988, Dec. 21, 1990
Next Issue: New Series, Vol. 251, No. 4990, Jan. 11, 1991



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