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Science, New Series, Vol. 292, No. 5517, Apr. 27, 2001


Previous Issue: New Series, Vol. 292, No. 5516, Apr. 20, 2001
Next Issue: New Series, Vol. 292, No. 5518, May 4, 2001


Front Matter (33 pp.)
Editorial: Disappearing Stem Cells, Disappearing Science, p. 601
Irving L. Weissman; David Baltimore

Editors' Choice, pp. 603+605
Gilbert Chin

Netwatch, p. 607
Jocelyn Kaiser


News


News of the Week
Universities, NIH Hear the Price Isn't Right on Essential Drugs, pp. 614-615
Eliot Marshall
Disputed AIDS Theory Dies Its Final Death, p. 615
Jon Cohen
Stem Cells Are Coaxed to Produce Insulin, pp. 615+617
Gretchen Vogel
ScienceScope, pp. 617+619
David Malakoff; Andrew Lawler; Jocelyn Kaiser
Images and Model Catch Planets as They Form, p. 618
Mark Muro
Critics of 'Halo Matter' Outrace the Presses, pp. 618-619
Mark Sincell
Two Pledges Boost SESAME Project, pp. 619-620
Robert Koenig
Reforms Could Threaten Facility Spending Hike, p. 620
Dennis Normile
New Gene May Be Key to Sweet Tooth, pp. 620-621
R. John Davenport
The First Urban Center in the Americas, pp. 621+623
Heather Pringle
How the Brain Understands Music, p. 623
Constance Holden


News Focus
The Mitochondrion: Is It Central to Apoptosis?, pp. 624-626
Elizabeth Finkel
Studying Humans: And Their Cousins and Parasites, pp. 627-629
Ann Gibbons
Bulmahn Is Bullish on Science Reforms, pp. 629-630
Robert Koenig; Gretchen Vogel
New Trips through the Back Alleys of Agriculture, pp. 631+633
Kathryn Brown
Random Samples, p. 635
Constance Holden


Science's Compass


Letters
GM Crops and Patterns of Pesticide Use, pp. 637-638
Janet Carpenter; L. LaReesa Wolfenbarger; Paul R. Phifer
Risk Assessment Data for GM Crops, pp. 638-639
Peter Gregory; Klaus von Grebmer; Orlo Ehart; L. LaReesa Wolfenbarger; Paul R. Phifer
Conflicts of Interest, p. 639
David Korn
Human Cloning: Not If, but When, p. 639
Geeta Chougule; Charlie Murtaugh


Corrections and Clarifications: Front Matter, p. 639
Corrections and Clarifications: A Sperm Cytoskeletal Protein That Signals Oocyte Meiotic Maturation and Ovulation, p. 639


Science's Compass


Policy Forum
Sustainability Science, pp. 641-642
Robert W. Kates; William C. Clark; Robert Corell; J. Michael Hall; Carlo C. Jaeger; Ian Lowe; James J. McCarthy; Hans Joachim Schellnhuber; Bert Bolin; Nancy M. Dickson; Sylvie Faucheux; Gilberto C. Gallopin; Arnulf Grübler; Brian Huntley; Jill Jäger; Narpat S. Jodha; Roger E. Kasperson; Akin Mabogunje; Pamela Matson; Harold Mooney; Berrien Moore III; Timothy O'Riordan; Uno Svedin


Books et al.
Not "A Piece of Cake"!, pp. 643-644
No Apparent Danger: The True Story of Volcanic Disaster at Galeras and Nevado del Ruiz
Victoria Bruce
Surviving Galeras
Stanley Williams; Fen Montaigne
Review author[s]: Haraldur Sigurdsson
The Shadow of Droughts' Deaths, pp. 644-645
Late Victorian Holocausts: El Niño Famines and the Making of the Third World
Mike Davis
Review author[s]: Vaclav Smil
More Than a Mass of Incandescent Gas, p. 645
The Sun from Space
Kenneth R. Lang
Review author[s]: J. R. Jokipii


Perspectives
Fighting Anthrax with a Mutant Toxin, pp. 647-648
Sjur Olsnes; Jørgen Wesche
Keeping Reactions under Quantum Control, pp. 648-649
Sean M. Hurley; A. Welford Castleman Jr.
Burn and Interrogate, pp. 650-651
Mildred S. Dresselhaus
Oxygenase Pathways: Oxo, Peroxo, and Superoxo, pp. 651-653
Lawrence Que Jr.; Yoshihito Watanabe
Pulling on Hair(pins), pp. 653-654
J. M. Fernandez; S. Chu; A. F. Oberhauser


Paleoclimate
Earth's Variable Climatic Past, p. 657
Jesse Smith; Julia Uppenbrink


News
Myriad Ways to Reconstruct past Climate, pp. 658-659
Erik Stokstad
The Tropics Return to the Climate System, pp. 660-661
Richard A. Kerr


Reviews
The Evolution of Climate over the Last Millennium, pp. 662-667
P. D. Jones; T. J. Osborn; K. R. Briffa
Cultural Responses to Climate Change during the Late Holocene, pp. 667-673
Peter B. deMenocal
Range Shifts and Adaptive Responses to Quaternary Climate Change, pp. 673-679
Margaret B. Davis; Ruth G. Shaw
Sea Level Change through the Last Glacial Cycle, pp. 679-686
Kurt Lambeck; John Chappell
Trends, Rhythms, and Aberrations in Global Climate 65 Ma to Present, pp. 686-693
James Zachos; Mark Pagani; Lisa Sloan; Ellen Thomas; Katharina Billups


Research


Research Articles
Dominant: Negative Mutants of a Toxin Subunit: An Approach to Therapy of Anthrax, pp. 695-697
Bret R. Sellman; Michael Mourez; R. John Collier
Direct Detection of Galactic Halo Dark Matter, pp. 698-702
B. R. Oppenheimer; N. C. Hambly; A. P. Digby; S. T. Hodgkin; D. Saumon


Reports
Energy Gaps in "Metallic" Single-Walled Carbon Nanotubes, pp. 702-705
Min Ouyang; Jin-Lin Huang; Chin Li Cheung; Charles M. Lieber
Engineering Carbon Nanotubes and Nanotube Circuits Using Electrical Breakdown, pp. 706-709
Philip G. Collins; Michael S. Arnold; Phaedon Avouris
Selective Bond Dissociation and Rearrangement with Optimally Tailored, Strong-Field Laser Pulses, pp. 709-713
Robert J. Levis; Getahun M. Menkir; Herschel Rabitz
A Complex Pattern of Mantle Flow in the Lau Backarc, pp. 713-716
Gideon P. Smith; Douglas A. Wiens; Karen M. Fischer; Leroy M. Dorman; Spahr C. Webb; John A. Hildebrand
Detection of Widespread Fluids in the Tibetan Crust by Magnetotelluric Studies, pp. 716-718
Wenbo Wei; Martyn Unsworth; Alan Jones; John Booker; Handong Tan; Doug Nelson; Leshou Chen; Shenghui Li; Kurt Solon; Paul Bedrosian; Sheng Jin; Ming Deng; Juanjo Ledo; David Kay; Brian Roberts
Observations of Ozone Formation in Power Plant Plumes and Implications for Ozone Control Strategies, pp. 719-723
T. B. Ryerson; M. Trainer; J. S. Holloway; D. D. Parrish; L. G. Huey; D. T. Sueper; G. J. Frost; S. G. Donnelly; S. Schauffler; E. L. Atlas; W. C. Kuster; P. D. Goldan; G. Hübler; J. F. Meagher; F. C. Fehsenfeld
Dating Caral, a Preceramic Site in the Supe Valley on the Central Coast of Peru, pp. 723-726
Ruth Shady Solis; Jonathan Haas; Winifred Creamer
Proapoptotic BAX and BAK: A Requisite Gateway to Mitochondrial Dysfunction and Death, pp. 727-730
Michael C. Wei; Wei-Xing Zong; Emily H. -Y. Cheng; Tullia Lindsten; Vily Panoutsakopoulou; Andrea J. Ross; Kevin A. Roth; Grant R. MacGregor; Craig B. Thompson; Stanley J. Korsmeyer
Allosteric Control of RNA Polymerase by a Site That Contacts Nascent RNA Hairpins, pp. 730-733
Innokenti Toulokhonov; Irina Artsimovitch; Robert Landick
Reversible Unfolding of Single RNA Molecules by Mechanical Force, pp. 733-737
Jan Liphardt; Bibiana Onoa; Steven B. Smith; Ignacio Tinoco Jr.; Carlos Bustamante
Switching Repulsion to Attraction: Changing Responses to Slit during Transition in Mesoderm Migration, pp. 737-740
Sunita G. Kramer; Thomas Kidd; Julie H. Simpson; Corey S. Goodman
Differentiation of Embryonic Stem Cell Lines Generated from Adult Somatic Cells by Nuclear Transfer, pp. 740-743
Teruhiko Wakayama; Viviane Tabar; Ivan Rodriguez; Anthony C. F. Perry; Lorenz Studer; Peter Mombaerts
Molecular Analyses of Oral Polio Vaccine Samples, pp. 743-744
Hendrik Poinar; Melanie Kuch; Svante Pääbo
Virus Maturation Involving Large Subunit Rotations and Local Refolding, pp. 744-748
J. F. Conway; W. R. Wikoff; N. Cheng; R. L. Duda; R. W. Hendrix; J. E. Johnson; A. C. Steven


AAAS News and Notes, pp. 751-752
Coimbra Sirica; Becky Ham

Back Matter (44 pp.)

Previous Issue: New Series, Vol. 292, No. 5516, Apr. 20, 2001
Next Issue: New Series, Vol. 292, No. 5518, May 4, 2001



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