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Science, New Series, Vol. 254, No. 5039, Dec. 20, 1991


Previous Issue: New Series, Vol. 254, No. 5038, Dec. 13, 1991
Next Issue: New Series, Vol. 255, No. 5040, Jan. 3, 1992


Volume Information (11 pp.)
Front Matter (14 pp.)
Molecule of the Year, p. 1705
Daniel E. Koshland Jr.

Buckyballs: Wide Open Playing Field for Chemists, pp. 1706-1709
Elizabeth Culotta; Daniel E. Koshland, Jr.


Letters
The Human Genome Project and Patents, pp. 1710+1712
Hubert Curien
Respect for Vitamin C, p. 1712
Linus Pauling; Gladys Block


ScienceScope, p. 1715
David P. Hamilton


News and Comment
Soviet Science: A Struggle for Survival, pp. 1716-1719
Steven Dickman
Breast Cancer: Stalemate In the War on Cancer, pp. 1719-1720
Eliot Marshall
Canadian Biotech Regs Under Fire, p. 1720
Douglas Powell
Fight Erupts Over DNA Fingerprinting, pp. 1721-1723
Leslie Roberts


Briefings
Britannica in the Doghouse, p. 1724
Constance Holden
Beryllium Disease, p. 1724
Constance Holden
Accounting for the Environment, p. 1724
Constance Holden
Radar Gun Hazards, pp. 1724-1725
Constance Holden
Computer Moguls Slam Data Plan, p. 1725
Constance Holden
More on Vitamin C, p. 1725
Constance Holden
Seal Tests, p. 1725
Constance Holden


Research News
On the Track of an Elusive Disease, pp. 1726-1728
Joseph Palca
A "Jumping Gene" Caught in the Act, pp. 1728-1729
David Holzman
HIV Risk Higher for First-Born Twins, p. 1729
Joseph Palca
Feverish Materialism in Snowy Boston, pp. 1730-1731
Ivan Amato
A Lofty Idea for Atmospheric Research, p. 1732
Richard Stone


Perspective
The Utility of DNA Typing in Forensic Work, pp. 1735-1739
Ranajit Chakraborty; Kenneth K. Kidd


Foreign Direct Investment in the United States and U.S. Interests, pp. 1740-1745
Edward M. Graham

Population Genetics in Forensic DNA Typing, pp. 1745-1750
R. C. Lewontin; Daniel L. Hartl

Oscillatory Kinetics and Spatio-Temporal Self-Organization in Reactions at Solid Surfaces, pp. 1750-1755
Gerhard Ertl

Linkage of Faulty Major Histocompatibility Complex Class I to Autoimmune Diabetes, pp. 1756-1761
Denise Faustman; Xiangping Li; Herbert Y. Lin; Yineng Fu; George Eisenbarth; Joseph Avruch; Jane Guo

Characterization of a Cofactor That Regulates Dimerization of a Mammalian Homeodomain Protein, pp. 1762-1767
Dirk B. Mendel; Paul A. Khavari; Pamela B. Conley; Mary K. Graves; Linda P. Hansen; Arie Admon; Gerald R. Crabtree


Reports
Fullerene Isomerism: Isolation of C 2v -C 78 and D3-C 78, pp. 1768-1770
François Diederich; Robert L. Whetten; Carlo Thilgen; Roland Ettl; Ito Chao; Marcos M. Alvarez
Long-Term Mean Vertical Motion over the Tropical Pacific: Wind-Profiling Doppler Radar Measurements, pp. 1771-1773
K. S. Gage; J. R. McAfee; D. A. Carter; W. L. Ecklund; A. C. Riddle; G. C. Reid; B. B. Balsley
A Fungal Gene for Antibiotic Resistance on a Dispensable ("B") Chromosome, pp. 1773-1776
Vivian P. Miao; Sarah F. Covert; Hans D. VanEtten
Identification and Characterization of Zinc Binding Sites in Protein Kinase C, pp. 1776-1779
Stevan R. Hubbard; W. Robert Bishop; Paul Kirschmeier; Simon J. George; Stephen P. Cramer; Wayne A. Hendrickson
Novel Fold and Putative Receptor Binding Site of Granulocyte-Macrophage Colony-Stimulating Factor, pp. 1779-1782
Kay Diederichs; Tom Boone; P. Andrew Karplus
Maintenance of Normoglycemia in Diabetic Mice by Subcutaneous Xenografts of Encapsulated Islets, pp. 1782-1784
Paul E. Lacy; Orion D. Hegre; Andriani Gerasimidi-Vazeou; Frank T. Gentile; Keith E. Dionne
Regulation of Phagocytosis and [Ca 2+ ]i Flux by Distinct Regions of Receptor, pp. 1785-1788
Joseph A. Odin; Jeffrey C. Edberg; Catherine J. Painter; Robert P. Kimberly; Jay C. Unkeless
Low Affinity Interaction of Peptide-MHC Complexes with T Cell Receptors, pp. 1788-1791
Kiyoshi Matsui; J. Jay Boniface; Philip A. Reay; Hansjörg Schild; Barbara Fazekas De St. Groth; Mark M. Davis
Identification of a Zinc Finger Protein That Inhibits IL-2 Gene Expression, pp. 1791-1794
T. M. Williams; D. Moolten; J. Burlein; J. Romano; R. Bhaerman; A. Godillot; M. Mellon; F. J. Rauscher III; J. A. Kant
Inhibition of Rap1A Binding to Cytochrome b 558 of NADPH Oxidase by Phosphorylation of Rap1A, pp. 1794-1796
Gary M. Bokoch; Lawrence A. Quilliam; Benjamin P. Bohl; Algirdas J. Jesaitis; Mark T. Quinn
Chloride Conductance Expressed by ΔF508 and Other Mutant CFTRs in Xenopus Oocytes, pp. 1797-1799
Mitchell L. Drumm; Daniel J. Wilkinson; Lisa S. Smit; Roger T. Worrell; Theresa V. Strong; Raymond A. Frizzell; David C. Dawson; Francis S. Collins
Inhibition of HIV Replication in Acute and Chronic Infections in Vitro by a Tat Antagonist, pp. 1799-1802
Ming-Chu Hsu; Andrew D. Schutt; Maureen Holly; Lee W. Slice; Michael I. Sherman; Douglas D. Richman; Mary Jane Potash; David J. Volsky
Long-Term Improvement of Hypercholesterolemia After ex Vivo Gene Therapy in LDLR-Deficient Rabbits, pp. 1802-1805
J. Roy Chowdhury; Mariann Grossman; Sanjeev Gupta; N. Roy Chowdhury; James R. Baker, Jr.; James M. Wilson
Isolation of an Active Human Transposable Element, pp. 1805-1808
Beth A. Dombroski; Stephen L. Mathias; Elizabeth Nanthakumar; Alan F. Scott; Haig H. Kazazian, Jr.
Reverse Transcriptase Encoded by a Human Transposable Element, pp. 1808-1810
Stephen L. Mathias; Alan F. Scott; Haig H. Kazazian Jr.; Jef D. Boeke; Abram Gabriel
Pharmacological Dissociation of Modulatory Effects of Serotonin in Aplysia Sensory Neurons, pp. 1811-1813
Alison R. Mercer; Nigel J. Emptage; Thomas J. Carew
Mitotic Phosphorylation of the Oct-1 Homeodomain and Regulation of Oct-1 DNA Binding Activity, pp. 1814-1816
Neil Segil; Susan Boseman Roberts; Nathaniel Heintz


Inside AAAS, pp. 1818-1819
Cynthia Lollar


Book Reviews
Revelations Reassessed, pp. 1820-1821
Manufacturing Knowledge. A History of the Hawthorne Experiments.
Richard Gillespie
Review author[s]: William Finlay
Men at Play, pp. 1821-1823
Southern Hunting in Black and White. Nature, History, and Ritual in a Carolina Community.
Stuart A. Marks
Review author[s]: Peggy F. Barlett
Geoculprit, pp. 1823-1824
The San Andreas Fault System, California.
Robert E. Wallace
Review author[s]: Steven Ward
Reprints of Books Previously Reviewed, p. 1824
Books Received, pp. 1824-1825


Back Matter (24 pp.)

Previous Issue: New Series, Vol. 254, No. 5038, Dec. 13, 1991
Next Issue: New Series, Vol. 255, No. 5040, Jan. 3, 1992



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