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Science, New Series, Vol. 250, No. 4987, Dec. 14, 1990


Previous Issue: New Series, Vol. 250, No. 4986, Dec. 7, 1990
Next Issue: New Series, Vol. 250, No. 4988, Dec. 21, 1990


Front Matter (16 pp.)
Incorporation of New Science Into Risk Assessment, p. 1497
Philip H. Abelson


Letters
When Kin Correlations Are Not Squared, p. 1498
Thomas J. Bouchard, Jr.; David T. Lykken; Matthew McGue; Nancy L. Segal; Auke Tellegen
Frazil Ice, p. 1498
Steven F. Daly
Imprisoned in Sudan, p. 1498
H. Brinnel; M. Cabanac; R. Hales; E. Nadel; T. Nagasaka
Carcinogenesis Debate, pp. 1498-1499
Bruce N. Ames; Lois S. Gold
Primate Research Institute: AIDS Research Program, p. 1499
Preston A. Marx; Karen Wright


News and Comment
Europe: Betting Heavily on Fusion, pp. 1500+1502
Jeremy Cherfas
U. S. Fusion Program: Struggling to Stay in the Game, p. 1501
Mark Crawford
Third Strike for NCI Breast Cancer Study, pp. 1503-1504
Eliot Marshall
Deficits Trip U.K. Science Funding Agencies, pp. 1504-1505
Jeremy Cherfas
Parallel Track: Where Should It Intersect Science?, pp. 1505-1506
P. J. Skerrett
NIH Panel: Bovine Hormone Gets the Nod, p. 1506
Ann Gibbons
Cold Fusion at Texas A&M: Problems, but No Fraud, pp. 1507-1508
Robert Pool
Brown Gets Science Committee Post, p. 1508
Joseph Palca
William Happer to Be DOE Research Chief?, p. 1508
Mark Crawford


Research News
Human Brain Disease Recreated In Mice, pp. 1509-1510
Jean Marx
Viewing the Universe as a Coat of Chain Mail, pp. 1510-1511
M. Mitchell Waldrop
Introns Pop up in New Places-What Does It Mean?, p. 1512
Marcia Barinaga
Nitrogenase Structure Revealed, p. 1513
Anne Simon Moffat


Briefings
Virology Dead, Says Duesberg, p. 1514
Constance Holden
Cyanide in Them Thar Hills?, p. 1514
Constance Holden
Hopeful News for CF Pilot Studies, pp. 1514-1515
Constance Holden
No Conflict on Conflict of Interest, p. 1515
Constance Holden
Paradigm Wars, p. 1515
Constance Holden
NEA Dumps on Science Art, p. 1515
Constance Holden


New Physicians: A Natural Experiment in Market Organization, pp. 1524-1528
Alvin E. Roth

Astrophysics and Cosmology Closing in on Neutrino Masses, pp. 1529-1533
Arnon Dar

A View of Interphase Chromosomes, pp. 1533-1540
Laura Manuelidis


Research Article
Interfacial Catalysis: The Mechanism of Phospholipase A2, pp. 1541-1546
David L. Scott; Steven P. White; Zbyszek Otwinowski; Wei Yuan; Michael H. Gelb; Paul B. Sigler


Reports
Melting of Diamond at High Pressure, pp. 1547-1549
Giulia Galli; Richard M. Martin; Roberto Car; Michele Parrinello
Stable Isotopic Evidence for a Pedogenic Origin of Carbonates in Trench 14 Near Yucca Mountain, Nevada, pp. 1549-1552
Jay Quade; Thure E. Cerling
The Kangmar Dome: A Metamorphic Core Complex in Southern Xizang (Tibet), pp. 1552-1556
Z. Chen; Y. Liu; K. V. Hodges; B. C. Burchfiel; L. H. Royden; C. Deng
Evolution of a Balanced Sex Ratio by Frequency-Dependent Selection in a Fish, pp. 1556-1558
David O. Conover; David A. Van Voorhees
Acetylcholine Binding by a Synthetic Receptor: Implications for Biological Recognition, pp. 1558-1560
Dennis A. Dougherty; David A. Stauffer
Crystal Structure of Cobra-Venom Phospholipase A2 in a Complex with a Transition-State Analogue, pp. 1560-1563
Steven P. White; David L. Scott; Zbyszek Otwinowski; Michael H. Gelb; Paul B. Sigler
Crystal Structure of Bee-Venom Phospholipase A2 in a Complex with a Transition-State Analogue, pp. 1563-1566
David L. Scott; Zbyszek Otwinowski; Michael H. Gelb; Paul B. Sigler
Bacterial Origin of a Chloroplast Intron: Conserved Self-Splicing Group I Introns in Cyanobacteria, pp. 1566-1570
Ming-Qun Xu; Scott D. Kathe; Heidi Goodrich-Blair; Sandra A. Nierzwicki-Bauer; David A. Shub
An Ancient Group I Intron Shared by Eubacteria and Chloroplasts, pp. 1570-1573
Maria G. Kuhsel; Roderick Strickland; Jeffrey D. Palmer
Complementation of the Mitotic Activator, p80 cdc25 , by a Human Protein-Tyrosine Phosphatase, pp. 1573-1576
Kathleen L. Gould; Sergio Moreno; Nicholas K. Tonks; Paul Nurse
Genetic Mechanisms of Tumor Suppression by the Human p53 Gene, pp. 1576-1580
Phang-Lang Chen; Yumay Chen; Robert Bookstein; Wen-Hwa Lee
Norwalk Virus Genome Cloning and Characterization, pp. 1580-1583
Xi Jiang; David Y. Graham; Kening Wang; Mary K. Estes
Homologous Recombination and Stable Transfection in the Parasitic Protozoan Trypanosoma brucei, pp. 1583-1587
Mary Gwo-Shu Lee; Lex H. T. Van Der Ploeg
Spontaneous Neurodegeneration in Transgenic Mice with Mutant Prion Protein, pp. 1587-1590
Karen K. Hsiao; Michael Scott; Dallas Foster; Darlene F. Groth; Stephen J. DeArmond; Stanley B. Prusiner
Broadly Neutralizing Antibodies Elicited by the Hypervariable Neutralizing Determinant of HIV-1, pp. 1590-1593
Kashi Javaherian; Alphonse J. Langlois; Greg J. LaRosa; Albert T. Profy; Dani P. Bolognesi; Walter C. Herlihy; Scott D. Putney; Thomas J. Matthews
Secretion of Neurotoxins by Mononuclear Phagocytes Infected with HIV-1, pp. 1593-1596
Dana Giulian; Ken Vaca; Christine A. Noonan
Poliovirus Mutants Resistant to Neutralization with Soluble Cell Receptors, pp. 1596-1599
Gerardo Kaplan; David Peters; Vincent R. Racaniello


Book Reviews
New Turnings, pp. 1600-1601
Reappraisals of the Scientific Revolution.
David C. Lindberg; Robert S. Westman
Review author[s]: Alan E. Shapiro
Lives of Chemists, pp. 1601-1602
From Cologne to Chapel Hill.
Ernest L. Eliel
The Right Place at the Right Time.
John D. Roberts
From Design to Discovery.
Donald J. Cram
Review author[s]: Joseph F. Bunnett
Storage Ecology, pp. 1602-1603
Food Hoarding in Animals.
Stephen B. Vander Wall
Review author[s]: David F. Sherry
Atoms and Laser Light, p. 1603
The Theory of Coherent Atomic Excitation.
Bruce W. Shore
Review author[s]: Kazimierz Rzazewski
Books Received, pp. 1603-1604


Back Matter (24 pp.)

Previous Issue: New Series, Vol. 250, No. 4986, Dec. 7, 1990
Next Issue: New Series, Vol. 250, No. 4988, Dec. 21, 1990



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