Science, New Series, Vol. 263, No. 5143, Jan. 7, 1994

Previous Issue: New Series, Vol. 262, No. 5142, Dec. 24, 1993
Next Issue: New Series, Vol. 263, No. 5144, Jan. 14, 1994

Front Matter (22 pp.)
Editorial: High-Energy Astrophysics, p. 11

David Lindley

Letters

Frog Endangerment, p. 13

Marshall P. Jones

Smallpox Virus Stocks, p. 13

David Baltimore

The Importance of Restaurants in Superconductivity Research, pp. 13-14

Bernard Raveau

Is Dioxin a Human Carcinogen?, p. 14

Alex Apostolou; Ann Gibbons

Accelerator Power Plants, pp. 14-15

Charles D. Bowman

Basic Research and Weather Prediction, p. 15

Peter V. Hobbs

Corrections and Clarifications: Carbon Monoxide: A Putative Neural Messenger, p. 15
Corrections and Clarifications: The Drift of Saturn's North Polar Spot Observed by the Hubble Space Telescope, p. 15
ScienceScope, p. 19

Richard Stone

News and Comment

The Aftermath of the Gallo Case, pp. 20-22

Christopher Anderson

Members Seek More Active Role, p. 23

Robert Langreth

German Geneticists Get Some Relief, pp. 23-24

Michael Simm

A Hearty Endorsement for Aspirin, p. 24

Peter Aldhous

Scientists Count a Rising Tide of Whales in the Seas, pp. 25-26

Karen Schmidt

Random Samples, p. 27

Constance Holden

Research News

Neutrino Watchers Go to Extremes, pp. 28-30

Gary Taubes

Cell Biologists Get the Message in New Orleans, pp. 30-31

Rachel Nowak

Genes Point to a New Identity For Pacific Pioneers, pp. 32-33

Ann Gibbons

High-Energy Astrophysics

Perspectives

Seeing the Nuclei of Active Galaxies, pp. 40-42

Anne L. Kinney

Recent Advances of X-ray Astronomy, pp. 42-44

Yasuo Tanaka

The Case of the Blue Stragglers, pp. 44-45

Charles Bailyn

Geminga and the Astronomy of Isolated Neutron Stars, pp. 46-47

Giovanni F. Bignami

Taking Stock of Gamma Ray Bursts, pp. 47-49

Dieter H. Hartmann

Astrophysical Opacity, pp. 50-55

Forrest J. Rogers; Carlos A. Iglesias

Astronomy and the Extreme Ultraviolet Explorer Satellite, pp. 55-59

Stuart Bowyer

Reports

Patterned Condensation Figures as Optical Diffraction Gratings, pp. 60-62

Amit Kumar; George M. Whitesides

Fluorescent X-ray Interference from a Protein Monolayer, pp. 62-64

Yuji C. Sasaki; Yoshio Suzuki; Tadashi Ishibashi

New Light on the Heart of Darkness of the Solar Chromosphere, pp. 64-66

S. K. Solanki; W. Livingston; T. Ayres

Void Structure in Colloidal Dispersions, pp. 66-68

Kensaku Ito; Hiroshi Yoshida; Norio Ise

Synthesis and Characterization of Molybdenum Carbide Clusters Mo_nC _4n (n = 1 to 4), pp. 68-71

Changming Jin; R. E. Haufler; R. L. Hettich; C. M. Barshick; R. N. Compton; A. A. Puretzky; A. V. Dem'yanenko; A. A. Tuinman

Do Hydrofluorocarbons Destroy Stratospheric Ozone?, pp. 71-75

A. R. Ravishankara; Andrew A. Turnipseed; Niels R. Jensen; Stephen Barone; Michael Mills; Carleton J. Howard; Susan Solomon

Target of the Transcriptional Activation Function of Phage λ cl Protein, pp. 75-77

Mei Li; Henry Moyle; Miriam M. Susskind

Catalytic Activity of an RNA Domain Derived from the U6-U4 RNA Complex, pp. 77-81

Jing-Hua Yang; Robert Cedergren; Bernardo Nadal-Ginard

Mitotic Repression of RNA Polymerase III Transcription in Vitro Mediated by Phosphorylation of a TFIIIB Component, pp. 81-84

Joel M. Gottesfeld; Veronica J. Wolf; Tam Dang; Douglass J. Forbes; Philippe Hartl

Location of cAMP-Dependent Protein Kinase Type I with the TCR-CD3 Complex, pp. 84-87

Bjørn S. Skålhegg; Kjetil Taskén; Vidar Hansson; Henrik S. Huitfeldt; Tore Jahnsen; Tor Lea

A Transforming Growth Factor β Type I Receptor That Signals to Activate Gene Expression, pp. 87-89

Craig H. Bassing; Jonathan M. Yingling; David J. Howe; Tongwen Wang; Wei Wu He; Michael L. Gustafson; Paresh Shah; Patricia K. Donahoe; Xiao-Fan Wang

Association of Transcription Factor APRF and Protein Kinase Jak1 with the Interleukin-6 Signal Transducer gp130, pp. 89-92

Claudia Lütticken; Ursula M. Wegenka; Juping Yuan; Jan Buschmann; Chris Schindler; Andrew Ziemiecki; Ailsa G. Harpur; Andrew F. Wilks; Kiyoshi Yasukawa; Tetsuya Taga; Tadamitsu Kishimoto; Giovanna Barbieri; Sandra Pellegrini; Michael Sendtner; Peter C. Heinrich; Friedemann Horn

Association and Activation of Jak-Tyk Kinases by CNTF-LIF-OSM-IL-6 β Receptor Components, pp. 92-95

Neil Stahl; Teri G. Boulton; Thomas Farruggella; Nancy Y. Ip; Sam Davis; Bruce A. Witthuhn; Frederick W. Quelle; Olli Silvennoinen; Giovanna Barbieri; Sandra Pellegrini; James N. Ihle; George D. Yancopoulos

Targeting of Gα _i2 to the Golgi by Alternative Spliced Carboxyl-Terminal Region, pp. 95-98

Jean-Pierre Montmayeur; Emiliana Borrelli

The Met Proto-Oncogene Mesenchymal to Epithelial Cell Conversion, pp. 98-101

Ilan Tsarfaty; Sing Rong; James H. Resau; Shen Rulong; Pedro Pinto da Silva; George F. Vande Woude

Technical Comments

Theory, Experiment, and the H + D₂ Reaction, p. 102

M. J. D'Mello; D. E. Manolopoulos; R. E. Wyatt; David W. Chandler

Book Reviews

Cold Fusion Revisited, pp. 105-106

Bad Science. The Short Life and Weird Times of Cold Fusion.

Gary Taubes

Review author[s]: Richard M. Crooks

Telescope Builders, pp. 106-107

Pauper and Prince. Ritchey, Hale, and Big American Telescopes.

Donald E. Osterbrock

Review author[s]: Gregory A. Good

Inbreeding and Evolution, pp. 107-108

The Natural History of Inbreeding and Outbreeding. Theoretical and Empirical Perspectives.

Nancy Wilmsen Thornhill

Review author[s]: Phil Hedrick

Auditory Cognition, pp. 108-109

Thinking in Sound. The Cognitive Psychology of Human Audition.

Stephen McAdams; Emmanuel Bigand

Review author[s]: William Yost

Books Received, p. 109

Back Matter (35 pp.)

Previous Issue: New Series, Vol. 262, No. 5142, Dec. 24, 1993
Next Issue: New Series, Vol. 263, No. 5144, Jan. 14, 1994

Science, New Series, Vol. 263, No. 5144, Jan. 14, 1994

Previous Issue: New Series, Vol. 263, No. 5143, Jan. 7, 1994
Next Issue: New Series, Vol. 263, No. 5145, Jan. 21, 1994

Front Matter (27 pp.)
Editorial: The Perversity of Inanimate Objects, p. 155

Daniel E. Koshland Jr.

Letters

Health Care Costs, pp. 157-159

A. R. Martin; Richard D. Krugman; Vincent A. Fulginiti; Michael E. DeBakey; Gordon H. Deckert

Corrections and Clarifications: Hearing Process Proves a Challenge for ORI, p. 159
Corrections and Clarifications: Single Molecules Observed by Near-Field Scanning Optical Microscopy, p. 159
ScienceScope, p. 163

Richard Stone

News and Comment

R&D Budget: More Wins Than Losses, pp. 164-165

Jeffrey Mervis; Christopher Anderson; Eliot Marshall

OSTP Plans a Blueprint for Research, pp. 165-166

Jeffrey Mervis

Battle Expands Over Shrinking Budget, p. 166

Andrey Allakhverdov

A Scheme for a High-Flying Scope, p. 167

Ann Finkbeiner

Management Faulted in Postmortem, pp. 167-168

John Travis

Academic Biotech Deals Offer More Promise Than Product, pp. 168-169

Lori Valigra

DOE Finds Physics Archives May Be Too Hot to Handle, p. 170

Christopher Anderson

Research News

Rise and Fall of the Y Chromosome, pp. 171-172

Virginia Morell

Unveiling a Tuberculosis Drug Target, p. 172

John Travis

Ancient Tropical Climates Warm San Francisco Gathering, pp. 173-175

Richard A. Kerr

A Family Tree of European Bears, p. 175

Alexander Dorozynski

Random Samples, pp. 176-177

Constance Holden

Perspectives

What is a Whale?, pp. 180-181

Annalisa Berta

What Are We? Where Did We Come From? Where Are We Going?, pp. 181-183

Luke O'Neill; Michael Murphy; Richard B. Gallagher

Surprising Signals in Plant Cells, pp. 183-184

Alan M. Jones

Carbon Pools and Flux of Global Forest Ecosystems, pp. 185-190

R. K. Dixon; S. Brown; R. A. Houghton; A. M. Solomon; M. C. Trexler; J. Wisniewski

The Transfer RNA Identity Problem: A Search for Rules, pp. 191-197

Margaret E. Saks; Jeffrey R. Sampson; John N. Abelson

Reports

Observed Impact of Snow Cover on the Heat Balance and the Rise of Continental Spring Temperatures, pp. 198-200

Pavel Ya. Groisman; Thomas R. Karl; Richard W. Knight

Nanometer Spatial Resolution Achieved in Hard X-Ray Imaging and Laue Diffraction Experiments, pp. 201-203

Donald H. Bilderback; Stephen A. Hoffman; Daniel J. Thiel

Free-Radical Side-Chain Bromination of Alkylaromatics in Supercritical Carbon Dioxide, pp. 203-205

James M. Tanko; Joseph F. Blackert

Quantum Yield for Production of CH₃NC in the Photolysis of CH₃NCS, pp. 205-207

Ramón A. Alvarez; C. Bradley Moore

Structure of Solidified Colloidal Array Laser Filters Studied by Cryogenic Transmission Electron Microscopy, pp. 207-210

Eduardo A. Kamenetzky; Lino G. Magliocco; Hans P. Panzer

Fossil Evidence for the Origin of Aquatic Locomotion in Archaeocete Whales, pp. 210-212

J. G. M. Thewissen; S. T. Hussain; M. Arif

An Inverted Double Seismic Zone in Chile: Evidence of Phase Transformation in the Subducted Slab, pp. 212-215

Diana Comte; Gerardo Suárez

Modes of Tilting During Extensional Core Complex Development, pp. 215-218

Drew S. Coleman; J. Douglas Walker

Turbulent Mixing Under Drifting Pack Ice in the Weddell Sea, pp. 218-221

Miles G. McPhee; Douglas G. Martinson

Root-Knot Nematode-Directed Expression of a Plant Root-Specific Gene, pp. 221-223

Charles H. Opperman; Christopher G. Taylor; Mark A. Conkling

Crystal Structure of the DNA Binding Domain of the Heat Shock Transcription Factor, pp. 224-227

Celia J. Harrison; A. Andrew Bohm; Hillary C. M. Nelson

inhA, a Gene Encoding a Target for Isoniazid and Ethionamide in Mycobacterium tuberculosis, pp. 227-230

Asesh Banerjee; Eugenie Dubnau; Annaik Quemard; V. Balasubramanian; Kyung Sun Um; Theresa Wilson; Des Collins; Geoffrey de Lisle; William R. Jacobs Jr.

Degeneration of a Nonrecombining Chromosome, pp. 230-232

William R. Rice

Innervation of the Heart and Its Central Medullary Origin Defined by Viral Tracing, pp. 232-234

Amelia Standish; Lynn W. Enquist; James S. Schwaber

The Adjuvant Effect of Interleukin-12 in a Vaccine Against Leishmania major, pp. 235-237

Luis C. C. Afonso; Tanya M. Scharton; Leda Q. Vieira; Maria Wysocka; Giorgio Trinchieri; Phillip Scott

Phase Shifting of the Circadian Clock by Induction of the Drosophila period Protein, pp. 237-240

Isaac Edery; Joan E. Rutila; Michael Rosbash

Book Reviews

Embattled Values, p. 252

Science and Anti-Science.

Gerald Holton

Review author[s]: David A. Hollinger

Questions of Enslavement, pp. 252-253

Visions of Caliban. On Chimpanzees and People.

Dale Peterson; Jane Goodall

Review author[s]: Matt Cartmill

Chemical Entrepreneur, pp. 253-254

Alfred Nobel. A Biography.

Alfred Nobel; Kenne Fant

Review author[s]: Anthony S. Travis

Quantum Mysteries, pp. 254-255

The Quantum Theory of Motion. An Account of the de Broglie-Bohm Causal Interpretation of Quantum Mechanics.

Peter R. Holland

Review author[s]: Sheldon Goldstein

The New Genetics, pp. 255-256

Human Gene Mutation.

David N. Cooper; Michael Krawczak

Review author[s]: Haig H. Kazazian Jr.

Books Received, pp. 256-257

Back Matter (35 pp.)

Previous Issue: New Series, Vol. 263, No. 5143, Jan. 7, 1994
Next Issue: New Series, Vol. 263, No. 5145, Jan. 21, 1994

Science, New Series, Vol. 263, No. 5145, Jan. 21, 1994

Previous Issue: New Series, Vol. 263, No. 5144, Jan. 14, 1994
Next Issue: New Series, Vol. 263, No. 5146, Jan. 28, 1994

Front Matter (28 pp.)
Editorial: U.S. Petroleum: Past and Future, p. 303

Philip H. Abelson

Letters

Italy's Role in EMBL, p. 305

Vittorio Sgaramella

Environmental Management, pp. 305-306

William R. Jordan III

Michigan Support for Faculty Member, p. 306

Walter Harrison

Trot and Pace, pp. 306-307

Robert Haas

Not Huxley's Student, pp. 307-308

David L. Hull

Good Songs, p. 308

Eugenie C. Scott; Edward F. Hawkins

Corrections and Clarifications: A Prize for Patient Listening, p. 308
ScienceScope, p. 311

Richard Stone

News and Comment

Can Carol Browner Reform EPA?, pp. 312-315

Richard Stone

Italy Throws EMBL Into Turmoil, p. 315

Peter Aldhous

Environmental R&D Shakeup Rattles the National Labs, p. 316

Richard Sietmann

Easy-to-Alter Digital Images Raise Fears of Tampering, pp. 317-318

Christopher Anderson

Technology for Turning Seeing Into Believing, p. 318

Gary Taubes

Research News

How Cells Cycle Toward Cancer, pp. 319-321

Jean Marx

Researchers Try to Build Time Machines for Microwaves, pp. 321-322

James Glanz

In Ancient Climate, Orbital Chaos?, p. 323

Larry Krumenaker

New Images Highlight Hubble Fix, p. 323

Faye Flam

Boning Up: Newly Isolated Proteins Heal Bad Breaks, pp. 324-325

Joseph Alper

Random Samples, pp. 326-327

Constance Holden

Perspectives

Lasers Without Inversion, pp. 337-338

Marlan O. Scully; Michael Fleischhauer

Polyketide Biosynthesis: Molecular Recognition or Genetic Programming?, pp. 338-340

David E. Cane

Detecting Climatic Change Signals: Are There Any "Fingerprints"?, pp. 341-347

Stephen H. Schneider

Research Article

Hin Recombinase Bound to DNA: The Origin of Specificity in Major and Minor Groove Interactions, pp. 348-355

Jin-An Feng; Reid C. Johnson; Richard E. Dickerson

Reports

Crystal Structure of the High-Pressure Phase of Solid CO₂, pp. 356-358

K. Aoki; H. Yamawaki; M. Sakashita; Y. Gotoh; K. Takemura

Wind Streaks on Venus: Clues to Atmospheric Circulation, pp. 358-361

Ronald Greeley; Gerald Schubert; Daniel Limonadi; Kelly C. Bender; William I. Newman; Peggy E. Thomas; Catherine M. Weitz; Stephen D. Wall

500,000-Year Stable Carbon Isotopic Record from Devils Hole, Nevada, pp. 361-365

Tyler B. Coplen; Isaac J. Winograd; Jurate M. Landwehr; Alan C. Riggs

Distinguishing the Direct and Indirect Products of a Gas-Surface Reaction, pp. 365-367

Charles T. Rettner; Daniel J. Auerbach

High-Performance Photorefractive Polymers, pp. 367-369

Martin Liphardt; Arosha Goonesekera; Brian E. Jones; Stephen Ducharme; James M. Takacs; Lei Zhang

Built for Jumping: The Design of the Frog Muscular System, pp. 370-372

Gordon J. Lutz; Lawrence C. Rome

Benefit to male Sailfin Mollies of Mating with Heterospecific Females, pp. 373-374

Ingo Schlupp; Cathy Marler; Michael J. Ryan

Structure of the Catalytic Domain of Fibroblast Collagenase Complexed with an Inhibitor, pp. 375-377

Brett Lovejoy; Anne Cleasby; Anne M. Hassell; Kelly Longley; Michael A. Luthe; Debra Weigl; Gerard McGeehan; Andrew B. McElroy; David Drewry; Millard H. Lambert; Steven R. Jordan

Stereospecific Acyl Transfers on the Erythromycin-Producing Polyketide Synthase, pp. 378-380

Andrew F. A. Marsden; Patrick Caffrey; Jesus F. Aparicio; Mark S. Loughran; James Staunton; Peter F. Leadlay

Rational Design of Potent, Bioavailable, Nonpeptide Cyclic Ureas as HIV Protease Inhibitors, pp. 380-384

Patrick Y. S. Lam; Prabhakar K. Jahdav; Charles J. Eyermann; C. Nicholas Hodge; Yu Ru; Lee T. Bacheler; James L. Meek; Michael J. Otto; Marlene M. Rayner; Y. Nancy Wong; Chong-Hwan Chang; Patricia C. Weber; David A. Jackson; Thomas R. Sharpe; Susan Erickson-Viitanen

Regulation of MHC Class I Transport by the Molecular Chaperone, Calnexin (p88, IP90), pp. 384-387

Michael R. Jackson; Myrna F. Cohen-Doyle; Per A. Peterson; David B. Williams

Retention of Unassembled Components of Integral Membrane Proteins by Calnexin, pp. 387-390

Sumati Rajagopalan; Yuhui Xu; Michael B. Brenner

Cell Membrane Resealing by a Vesicular Mechanism Similar to Neurotransmitter Release, pp. 390-393

Richard A. Steinhardt; Guoqiang Bi; Janet M. Alderton

Book Reviews

Microbial Servants, p. 400

The Clostridia and Biotechnology.

D. R. Woods

Review author[s]: Eva R. Kashket

Life in Harsh Habitats, pp. 401-402

Antarctic Microbiology.

E. Imre Friedmann; Anne B. Thistle

Review author[s]: Edward F. DeLong

Recipes for Disaster, pp. 402-403

Volcanoes. A Planetary Perspective.

Peter Francis

Review author[s]: Jonathan Fink

Radio Days, pp. 403-404

Beyond Southern Skies. Radio Astronomy and the Parkes Telescope.

Peter Robertson

Review author[s]: R. D. Davies

Books Received, pp. 404-405

Back Matter (35 pp.)

Previous Issue: New Series, Vol. 263, No. 5144, Jan. 14, 1994
Next Issue: New Series, Vol. 263, No. 5146, Jan. 28, 1994

Science, New Series, Vol. 263, No. 5146, Jan. 28, 1994

Previous Issue: New Series, Vol. 263, No. 5145, Jan. 21, 1994
Next Issue: New Series, Vol. 263, No. 5147, Feb. 4, 1994

Front Matter (30 pp.)
Editorial: Earthquakes and Collective Action, p. 451

Daniel E. Koshland Jr.; Brooks Hanson

Letters

Minnesota Drug Sales, p. 453

Kathryn C. Zoon; Nils Hasselmo

Heavy Ion Drivers, pp. 453-454

Burton Richter

ApoE, Amyloid, and Alzheimer's Disease, pp. 454-455

John Hardy

Academic Decision-Making, p. 455

Troy Shinbrot

For the Record, p. 455

Stephen L. Mayo; Robert L. Baldwin

Corrections and Clarifications: A Link between Cyclin A Expression and Adhesion-Dependent Cell Cycle Progression, p. 455
ScienceScope, p. 459

Richard Stone

News

How Many More After Northridge?, pp. 460-461

Richard A. Kerr

Letters Provoke Unintended Response, p. 461

Michael Balter

Japan's H-II Rocket to Bolster Remote Sensing Projects, p. 462

Dennis Normile

Peer Review Triumphs Over Lobbying, p. 463

Jon Cohen

Researchers Nervous About Bioethics Bill, pp. 463-464

Michael Balter

Another Shakeup at LBL Genome Center, p. 464

Christopher Anderson

New Randon Study: No Smoking Gun, p. 465

Richard Stone

Expected Increase Becomes a Cut, p. 465

Michael Simm

Learning by Diffusion: Nitric Oxide May Spread Memories, p. 466

Marcia Barinaga

Hubble Repair and More Wins Astronomers' Acclaim, pp. 467-468

John Travis

Random Samples, p. 469

Constance Holden

Special News Report

Radiation: Balancing the Record, pp. 470-472+473

Charles C. Mann

Political Fallout: A National Bioethics Board?, p. 473

Eliot Marshall

Policy Forum

Ecological and Genetic Factors in Conservation: A Cautionary Tale, pp. 485-486

T. M. Caro; M. Karen Laurenson

Perspectives

Molecular Geometry and Nonlinear Optics, pp. 487-488

J. L. Brédas

α-Helical Coiled Coils: More Facts and Better Predictions, pp. 488-489

Carolyn Cohen; David A. D. Parry

Molecular Dynamics in Liquids: Spin-Lattice Relaxation of Nitroxide Spin Labels, pp. 490-493

Bruce H. Robinson; Duncan A. Haas; Colin Mailer

Research Article

Life on Land in the Precambrian, pp. 494-498

Robert J. Horodyski; L. Paul Knauth

Reports

Dynamics Affecting the Primary Charge Transfer in Photosynthesis, pp. 499-502

John N. Gehlen; Massimo Marchi; David Chandler

Decomposition of the Modulated Waves in a Rotating Couette System, pp. 502-505

Yasushi Takeda; Walter E. Fischer; Jun Sakakibara

Constraints on Transport and Kinetics in Hydrothermal Systems from Zoned Garnet Crystals, pp. 505-508

Bjorn Jamtveit; Richard L. Hervig

Glacial-Interglacial Changes in Moisture Sources for Greenland: Influences on the Ice Core Record of Climate, pp. 508-511

C. D. Charles; D. Rind; J. Jouzel; R. D. Koster; R. G. Fairbanks

Large First Hyperpolarizabilities in Push-Pull Polyenes by Tuning of the Bond Length Alternation and Aromaticity, pp. 511-514

Seth R. Marder; Lap-Tak Cheng; Bruce G. Tiemann; Andrienne C. Friedli; Mireille Blanchard-Desce; Joseph W. Perry; Jørgen Skindhøj

Meiosis-Induced Double-Strand Break Sites Determined by Yeast Chromatin Structure, pp. 515-518

Tzu-Chen Wu; Michael Lichten

Effective Tumor Vaccine Generated by Fusion of Hepatoma Cells with Activated B Cells, pp. 518-520

Yajun Guo; Mengchao Wu; Hen Chen; Xiaoning Wang; Guangluo Liu; Guanglo Li; Jing Ma; Man-Sun Sy

Parallel Neuronal Mechanisms for Short-Term Memory, pp. 520-522

Earl K. Miller; Robert Desimone

Phospholipase D: A Downstream Effector of ARF in Granulocytes, pp. 523-526

Shamshad Cockcroft; Geraint M. H. Thomas; Amanda Fensome; Blandine Geny; Emer Cunningham; Ivan Gout; Ian Hiles; Nicholas F. Totty; Oanh Truong; J. Justin Hsuan

Maspin, a Serpin with Tumor-Suppressing Activity in Human Mammary Epithelial Cells, pp. 526-529

Zhiqiang Zou; Anthony Anisowicz; Mary J. C. Hendrix; Ann Thor; Mark Neveu; Shijie Sheng; Kristina Rafidi; Elisabeth Seftor; Ruth Sager

Visualization of Quantal Synaptic Transmission by Dendritic Calcium Imaging, pp. 529-532

Timothy H. Murphy; Jay M. Baraban; W. Gil Wier; Lothar A. Blatter

Locally Distributed Synaptic Potentiation in the Hippocampus, pp. 532-536

Erin M. Schuman; Daniel V. Madison

Technical Comments

Experimental Support for the "Hydrophobic Zipper" Hypothesis, p. 536

Angela M. Gronenborn; G. Marius Clore

Alzheimer's Disease and Possible Gene Interaction, p. 537

P. St George-Hyslop; D. Crapper McLachlan; T. Tuda; E. Rogaev; H. Karlinsky; C. F. Lippa; D. Pollen; M. A. Pericak-Vance; E. H. Corder; A. M. Saunders; P. C. Gaskill; W. J. Strittmatter; A. D. Roses; D. E. Schmechel; G. W. Small; J. L. Haines

Book Reviews

Arrangements for Advanced Training, pp. 543-544

The Research Foundations of Graduate Education. Germany, Britain, France, United States, Japan.

Burton R. Clark

Review author[s]: Olga Amsterdamska

Acaropathology, pp. 544-545

Ecology and Environmental Management of Lyme Disease.

Howard S. Ginsberg

Review author[s]: James H. Oliver Jr.

Photosynthesis, pp. 545-546

The Photosynthetic Reaction Center.

Johann Deisenhofer; James R. Norris

Review author[s]: Wim F. J. Vermaas

The Gram-Positive World, pp. 546-548

Bacillus subtilis and Other Gram-Positive Bacteria. Biochemistry, Physiology, and Molecular Genetics.

Abraham L. Sonenshein; James A. Hoch; Richard Losick

Review author[s]: Kenneth F. Bott

Books Received, p. 548

Inside AAAS, pp. 549-551

Diana Pabst

Back Matter (29 pp.)

Previous Issue: New Series, Vol. 263, No. 5145, Jan. 21, 1994
Next Issue: New Series, Vol. 263, No. 5147, Feb. 4, 1994

Science, New Series, Vol. 263, No. 5147, Feb. 4, 1994

Previous Issue: New Series, Vol. 263, No. 5146, Jan. 28, 1994
Next Issue: New Series, Vol. 263, No. 5148, Feb. 11, 1994

Front Matter (18 pp.)
Editorial: Reflections on the Environment, p. 591

Philip H. Abelson

Letters

ORI and Misconduct Investigations, p. 593

Lyle W. Bivens

Incorporating Minorities in Science, pp. 593-595

David L. Brautigan; Martin Gellert; Robert M. Hoyte; Thomas D. Landefeld; Thomas Cameron

Triple Repeat DNA as a Highly Mutable Regulatory Mechanism, pp. 595-596

David G. King

Genetics and Violent Crime, p. 596

I. Tinoco Jr.

Corrections and Clarifications: DNA Sequence Determination by Hybridization: A Strategy for Efficient Largescale Sequencing, p. 596
ScienceScope, p. 599

Richard Stone

News and Comment

New Fight Over Fetal Tissue Grafts, pp. 600-601

Jon Cohen

Fetal Tissue Research on the Rebound, p. 601

Larry Thompson

New Law Brings Affirmative Action to Clinical Research, p. 602

Eliot Marshall

Panel Proposes Guidelines for Industry, p. 603

Christopher Anderson

ERATO Grows Beyond Its Borders, pp. 603-604

Dennis Normile

A Strategic Message From Mikulski, p. 604

Jeffrey Mervis

A Costly Settlement Ends Whistle-Blower Suit, p. 605

Gary Taubes

Random Samples, pp. 606-607

Constance Holden

Research News

Mining Treasures from 'Junk DNA', pp. 608-610

Rachel Nowak

Watching New Developments-Live, p. 610

John Travis

Did Early Humans Reach Siberia 500,000 Years Ago?, pp. 611-612

Virginia Morell

Inertia: Does Empty Space Put Up the Resistance?, pp. 612-613

Robert Matthews

Math Attendees Find There's Life After Fermat Proof, pp. 614-615

Barry Cipra

Science After the Cold War

[Introduction], p. 619

Researchers Sift the Ashes of SDI, pp. 620-623

Eliot Marshall

Ex-Defense Scientists Come in From the Cold, pp. 623-624

Faye Flam

The Defense Department Declassifies the Earth-Slowly, pp. 625-626

Richard A. Kerr

Nonproliferation Boom Gives A Lift to the National Labs, pp. 627-629

Christopher Anderson

No Easy Way to Shackle The Nuclear Demon, pp. 629-631

Gary Taubes

Policy Forum

Nuclear Test Ban Monitoring: New Requirements, New Resources, pp. 634-635

Gregory E. van der Vink; Jeffrey Park

Perspectives

Toward New Multi-Property Materials, pp. 636-637

Jean-François Nicoud

Remodeling Schemes of Intracellular Pathogens, pp. 637-639

Pamela L. C. Small; Lalita Ramakrishnan; Stanley Falkow

DNA Replication Origins in Animal Cells: A Question of Context?, pp. 639-640

William C. Burhans; Joel A. Huberman

Verification, Validation, and Confirmation of Numerical Models in the Earth Sciences, pp. 641-646

Naomi Oreskes; Kristin Shrader-Frechette; Kenneth Belitz

Research Article

Routes to Catalysis: Structure of a Catalytic Antibody and Comparison with Its Natural Counterpart, pp. 646-652

Matthew R. Haynes; Enrico A. Stura; Donald Hilvert; Ian A. Wilson

Reports

A Magnetohydrodynamic Model of Solar Wind Interaction with Asteroid Gaspra, pp. 653-655

Klaus Baumgärtel; Konrad Sauer; Alexander Bogdanov

Electric Field-Induced Concentration Gradients in Lipid Monolayers, pp. 655-658

Ka Yee C. Lee; Jürgen F. Klingler; Harden M. McConnell

Stilbazolium-MPS₃ Nanocomposites with Large Second-Order Optical Nonlinearity and Permanent Magnetization, pp. 658-660

Pascal G. Lacroix; René Clément; Keitaro Nakatani; Joseph Zyss; Isabelle Ledoux

Paleoindians in Beringia: Evidence from Arctic Alaska, pp. 660-662

Michael L. Kunz; Richard E. Reanier

Tropical Temperature Variations Since 20,000 Years Ago: Modulating Interhemispheric Climate Change, pp. 663-665

Thomas P. Guilderson; Richard G. Fairbanks; James L. Rubenstone

Lake-Atmosphere Feedbacks Associated with Paleolakes Bonneville and Lahontan, pp. 665-668

S. W. Hostetler; F. Giorgi; G. T. Bates; P. J. Bartlein

Mortality Rates in a Genetically Heterogeneous Population of Caenorhabditis elegans, pp. 668-671

Anne Brooks; Gordon J. Lithgow; Thomas E. Johnson

Zinc Finger Phage: Affinity Selection of Fingers with New DNA-Binding Specificities, pp. 671-673

Edward J. Rebar; Carl O. Pabo

Levels of Peripheral T Cell Tolerance Induced by Different Doses of Tolerogen, pp. 674-676

Iris Ferber; Günther Schönrich; Johannes Schenkel; Andrew L. Mellor; Günter J. Hämmerling; Bernd Arnold

Natural Vertical Transmission of Western Equine Encephalomyelitis Virus in Mosquitoes, pp. 676-678

C. F. Fulhorst; J. L. Hardy; B. F. Eldridge; S. B. Presser; W. C. Reeves

Lack of Acidification in Mycobacterium Phagosomes Produced by Exclusion of the Vesicular Proton-ATPase, pp. 678-681

Sheila Sturgill-Koszycki; Paul H. Schlesinger; Prasanta Chakraborty; Pryce L. Haddix; Helen L. Collins; Agnes K. Fok; Richard D. Allen; Stephen L. Gluck; John Heuser; David G. Russell

Magnetic Resonance Microscopy of Embryonic Cell Lineages and Movements, pp. 681-684

Russell E. Jacobs; Scott E. Fraser

Disruption of PDGF Receptor Trafficking by Mutation of Its PI-3 Kinase Binding Sites, pp. 684-687

Marguerite Joly; Andrius Kazlauskas; Fredric S. Fay; Silvia Corvera

Nitric Oxide Activation of Poly(ADP-Ribose) Synthetase in Neurotoxicity, pp. 687-689

Jie Zhang; Valina L. Dawson; Ted M. Dawson; Solomon H. Snyder

Adenosine Inhibition of Mesopontine Cholinergic Neurons: Implications for EEG Arousal, pp. 689-692

Donald G. Rainnie; Heinz C. R. Grunze; Robert W. McCarley; Robert W. Greene

Associative Odor Learning in Drosophila Abolished by Chemical Ablation of Mushroom Bodies, pp. 692-695

J. Steven de Belle; Martin Heisenberg

Technical Comment

Envisioning a Quantum Supercomputer, p. 695

Seth Lloyd

Book Reviews

An Envisioning of Consciousness, p. 696

The Astonishing Hypothesis. The Scientific Search for the Soul.

Francis Crick

Review author[s]: J. J. Hopfield

"Spandrels" Dissected, p. 697

Understanding Scientific Prose.

Jack Selzer

Review author[s]: Keith Stewart Thomson

Biomedical Progenitor, pp. 697-698

Archibald Garrod and the Individuality of Man.

Alexander G. Bearn

Review author[s]: James V. Neel

Quantum Technology, p. 699

Quantum Well Lasers.

Peter S. Zory, Jr.

Review author[s]: Kerry Vahala

Reprints of Books Previously Reviewed, p. 699

Books Received, pp. 699-701

Back Matter (23 pp.)

Previous Issue: New Series, Vol. 263, No. 5146, Jan. 28, 1994
Next Issue: New Series, Vol. 263, No. 5148, Feb. 11, 1994

Science, New Series, Vol. 263, No. 5148, Feb. 11, 1994

Previous Issue: New Series, Vol. 263, No. 5147, Feb. 4, 1994
Next Issue: New Series, Vol. 263, No. 5149, Feb. 18, 1994

Front Matter (30 pp.)
Editorial: The Path to Research Prioritization, p. 735

Daniel E. Koshland Jr.

Letters

NIH Neural Transplantation Funding, p. 737

Håkan Widner

Alloimmunization to Prevent AIDS?, pp. 737-738

Dobri D. Kiprov; Haynes W. Sheppard; Carl V. Hanson

Astronomy: Fundamental Value, pp. 738-739

Mark E. Bailey

Corrections and Clarifications: "Involvement of U6 snRNA in 5' splice site selection., p. 739

Corrections and Clarifications: The Deadly Latur Earthquake, p. 739

Corrections and Clarifications: The U5 and U6 small Nuclear RNAs as active site components of the Spliceosome, p. 739

ScienceScope, p. 743

Richard Stone

News and Comment

R&D Budget: Growth in Hard Times, pp. 744-746

Jeffrey Mervis

Hughes to Add 49 New Investigators, p. 746

Eliot Marshall

Researchers Sue to Get Reviewer Names, p. 747

Eliot Marshall

Academy Warns Against Slipping Ethics, p. 747

Christopher Anderson

Safety Concerns Halt U. K. Study, p. 748

Sharon Kingman

National Labs Under Review, Again, p. 748

Christopher Anderson

Physicists Struggle for Consensus About the Future, p. 749

Faye Flam

Inside Look Confirms More Radiation, p. 750

John Travis

Gloomy Picture for Photo Astronomers, pp. 750-751

John Travis

Methane Increase Put on Pause, p. 751

Richard A. Kerr

U.S. Research Forum Fails To Find a Common Front, p. 752

Jeffrey Mervis

Random Samples, p. 753

Constance Holden

Research News

Cell Suicide: By ICE, Not Fire, pp. 754-756

Marcia Barinaga

Solar Physicists Peer Into a Mysterious Furnace, pp. 756-757

James Glanz

Will Molecular Data Set The Stage for a Synthesis?, p. 758

Jon Cohen

A New Portrait of Venus: Thick-Skinned and Decrepit, pp. 759-760

Richard A. Kerr

Perspective

Protein-DNA Recognition: New Perspectives and Underlying Themes, pp. 769-770

Peter H. von Hippel

Population Policy Options in the Developing World, pp. 771-776

John Bongaarts

Research Article

Coupling of Local Folding to Site-Specific Binding of Proteins to DNA, pp. 777-784

Ruth S. Spolar; M. Thomas Record Jr.

Reports

Destruction Rate of H₃⁺ by Low-Energy Electrons Measured in a Storage-Ring Experiment, pp. 785-787

G. Sundström; J. R. Mowat; H. Danared; S. Datz; L. Broström; A. Filevich; A. Källberg; S. Mannervik; K. G. Rensfelt; P. Sigray; M. af Ugglas; M. Larsson

Hubble Space Telescope Observations of Comet P/Shoemaker-Levy 9 (1993e), pp. 787-791

H. A. Weaver; P. D. Feldman; M. F. A'Hearn; C. Arpigny; R. A. Brown; E. F. Helin; D. H. Levy; B. G. Marsden; K. J. Meech; S. M. Larson; K. S. Noll; J. V. Scotti; Z. Sekanina; C. S. Shoemaker; E. M. Shoemaker; T. E. Smith; A. D. Storrs; D. K. Yeomans; B. Zellner

Theoretical Evidence for a C ₆₀ "Window" Mechanism, pp. 791-793

Robert L. Murry; Gustavo E. Scuseria

Suppression of Rupture in Thin, Nonwetting Liquid Films, pp. 793-795

Rachel Yerushalmi-Rozen; Jacob Klein; Lewis J. Fetters

The Timing of High Sea Levels Over the Past 200,000 Years, pp. 796-800

Christina D. Gallup; R. Lawrence Edwards; Robert G. Johnson

Nanowire Array Composites, pp. 800-802

C. A. Huber; T. E. Huber; M. Sadoqi; J. A. Lubin; S. Manalis; C. B. Prater

Green Fluorescent Protein as a Marker for Gene Expression, pp. 802-805

Martin Chalfie; Yuan Tu; Ghia Euskirchen; William W. Ward; Douglas C. Prasher

RNA Polymerase II Initiation Factor Interactions and Transcription Start Site Selection, pp. 805-807

Yang Li; Peter M. Flanagan; Herbert Tschochner; Roger D. Kornberg

Transcriptional Activation Modulated by Homopolymeric Glutamine and Proline Stretches, pp. 808-811

Hans-Peter Gerber; Katja Seipel; Oleg Georgiev; Manuela Höfferer; Martin Hug; Sandro Rusconi; Walter Schaffner

Promoter-Selective Transcriptional Defect in Cell Cycle Mutant ts13 Rescued by hTAF_II 250, pp. 811-814

Edith H. Wang; Robert Tjian

Mapping the Lectin-Like Activity of Tumor Necrosis Factor, pp. 814-817

Rudolf Lucas; Stefan Magez; Robert De Leys; Lucie Fransen; Jean-Pierre Scheerlinck; Murielle Rampelberg; Erwin Sablon; Patrick De Baetselier

Mesodermal Patterning by a Gradient of the Vertebrate Homeobox Gene goosecoid, pp. 817-820

Christof Niehrs; Herbert Steinbeisser; Eddy M. De Robertis

Neuronal Activity During Different Behaviors in Aplysia: A Distributed Organization?, pp. 820-823

Jian-Young Wu; Lawrence B. Cohen; Chun Xiao Falk

In Vivo Ca ²⁺ Dynamics in a Cricket Auditory Neuron: An Example of Chemical Computation, pp. 823-826

Erik C. Sobel; David W. Tank

Prevention of Vertebrate Neuronal Death by the crmA Gene, pp. 826-828

Valeria Gagliardini; Pierre-Alain Fernandez; Robert K. K. Lee; Hannes C. A. Drexler; Rocco J. Rotello; Mark C. Fishman; Junying Yuan

Book Reviews

Science by Worst Cases, pp. 837-838

The Golem. What Everyone Should Know About Science.

Harry Collins; Trevor Pinch

Review author[s]: Ullica Segerstråle

American Plants, pp. 838-839

Flora of North America North of Mexico. Flora of North America Editorial Committee. Vols. 1 and 2.

Review author[s]: Robert Ornduff

Plasmid Transfer, pp. 839-841

Bacterial Conjugation.

Don B. Clewell

Review author[s]: James A. Shapiro

The Dyslexic Brain, pp. 841-842

Dyslexia and Development. Neurobiological Aspects of Extra-Ordinary Brains.

Albert M. Galaburda

Review author[s]: George W. Hynd

Books Received, p. 842

Back Matter (46 pp.)

Previous Issue: New Series, Vol. 263, No. 5147, Feb. 4, 1994
Next Issue: New Series, Vol. 263, No. 5149, Feb. 18, 1994

Science, New Series, Vol. 263, No. 5149, Feb. 18, 1994

Previous Issue: New Series, Vol. 263, No. 5148, Feb. 11, 1994
Next Issue: New Series, Vol. 263, No. 5150, Feb. 25, 1994

Front Matter (28 pp.)
Editorial: Science in the National Interest, p. 899

Philip H. Abelson

Letters

Psychiatry at UCSF, p. 901

Robert S. Wallerstein; Herbert Weiner; Marcia Barinaga

Truth in Super Collider Criticism, pp. 902-903

Robert N. Cahn; J. David Jackson; Chris Quigg; David F. Voss; Daniel E. Koshland Jr.

Mathematical Development and Language, p. 903

David C. Geary; Robert S. Siegler

Smallpox Virus Stocks: More Votes, pp. 903-904

William J. Turner; Parker A. Small Jr.

Corrections and Clarifications: HHMI Cuts Cardiologist Loose, p. 904
Corrections and Clarifications: Alzheimer's Disease and Possible Gene Interaction, p. 904
Corrections and Clarifications: Processing the New Coke Fiasco, p. 904
ScienceScope, p. 907

Richard Stone

News and Comment

The Coming Crunch for Space Science, pp. 908-909

Christopher Anderson

NIH Drops Bid for Gene Patents, pp. 909-910

Christopher Anderson

Restating the Risks of Tamoxifen, pp. 910-911

Lisa Seachrist

Race to Synthesize Taxol Ends in a Tie, p. 911

Faye Flam

California's Disposal Plan Goes Nowhere Fast, p. 912

Jon Cohen

Molecular Biology With a Strong Southern Accent, pp. 913+915

Peter Aldhous

The Trials and Tribulations of Building a Lab in the South, p. 914

Patricia Kahn

Research News

Beam Me Up to the New Physics!, pp. 916+918

Faye Flam

First Stop on the Neutrino Roadshow: CERN, p. 917

Daniel Clery

Is Marine Biodiversity At Risk?, pp. 918-920

Elizabeth Culotta

All Strung Out at the Synapse, pp. 920-921

Rachel Nowak

Recreating the Universe's Fateful Flaws, p. 921

Tim Appenzeller

Random Samples, pp. 922-923

Constance Holden

Perspective

Tropical Diversity and Global Change, pp. 933-934

Stuart L. Pimm; Andrew M. Sugden

An Empirical Test of Recruitment Limitation in a Coral Reef Fish, pp. 935-939

Peter Doherty; Tony Fowler

Reports

Shape of Asteroid 4769 Castalia (1989 PB) from Inversion of Radar Images, pp. 940-943

R. Scott Hudson; Steven J. Ostro

The Cosmological Kibble Mechanism in the Laboratory: String Formation in Liquid Crystals, pp. 943-945

Mark J. Bowick; L. Chandar; E. A. Schiff; Ajit M. Srivastava

Laser-Based Analysis of Carbon Isotope Ratios, pp. 945-947

D. E. Murnick; B. J. Peer

The Dependence of Electron Transfer Efficiency on the Conformational Order in Organic Monolayers, pp. 948-950

Avner Haran; David H. Waldeck; Ron Naaman; Ellen Moons; David Cahen

Crystal Structure, Bonding, and Phase Transition of the Superconducting Na₂CsC ₆₀ Fulleride, pp. 950-954

Kosmas Prassides; Christos Christides; Ian M. Thomas; Junichiro Mizuki; Katsumi Tanigaki; Ichiro Hirosawa; Thomas W. Ebbesen

Increasing Turnover Through Time in Tropical Forests, pp. 954-958

O. L. Phillips; A. H. Gentry

Magnetic Field Effects on B ₁₂ Ethanolamine Ammonia Lyase: Evidence for a Radical Mechanism, pp. 958-960

Timothy T. Harkins; Charles B. Grissom

Antigenic Diversity and the Transmission Dynamics of Plasmodium falciparum, pp. 961-963

Sunetra Gupta; Katharine Trenholme; Roy M. Anderson; Karen P. Day

Diverse Essential Functions Revealed by Complementing Yeast Calmodulin Mutants, pp. 963-966

Yoshikazu Ohya; David Botstein

Agmatine: An Endogenous Clonidine-Displacing Substance in the Brain, pp. 966-969

Gen Li; S. Regunathan; Colin J. Barrow; Jamshid Eshraghi; Raymond Cooper; Donald J. Reis

Reduction in Viscosity of Cystic Fibrosis Sputum in Vitro by Gelsolin, pp. 969-971

Carol A. Vasconcellos; Philip G. Allen; Mary Ellen Wohl; Jeffrey M. Drazen; Paul A. Janmey; Thomas P. Stossel

Kinetics of Molecular Chaperone Action, pp. 971-973

Daniel Schmid; Antonio Baici; Heinz Gehring; Philipp Christen

Role of NO Production in NMDA Receptor-Mediated Neurotransmitter Release in Cerebral Cortex, pp. 973-977

P. Read Montague; Carolyn D. Gancayco; Mark J. Winn; Richard B. Marchase; Michael J. Friedlander

Paralysis and Early Death in Cysteine String Protein Mutants of Drosophila, pp. 977-980

Konrad E. Zinsmaier; Kai K. Eberle; Erich Buchner; Niklaus Walter; Seymour Benzer

Cysteine String Proteins: A Potential Link Between Synaptic Vesicles and Presynaptic Ca ²⁺ Channels, pp. 981-982

Alessandro Mastrogiacomo; Stanley M. Parsons; Guido A. Zampighi; Donald J. Jenden; Joy A. Umbach; Cameron B. Gundersen

Technical Comments

Triethylsilyl Cations, pp. 983-986

Linus Pauling; George A. Olah; Golam Rasul; Xing-ya Li; Herwig A. Buchholz; Graham Sandford; G. K. Surya Prakash; Joseph B. Lambert; Shizhong Zhang; Christopher A. Reed; Zuowei Xie

Ca ²⁺ -Induced Ca ²⁺ Release in Response to Flash Photolysis, pp. 986-988

G. D. Lamb; M. W. Fryer; D. G. Stephenson; Sandor Györke; Michael Fill

Fertilization and Ion Channels, p. 988

Richard Nuccitelli; James E. Ferguson; Daphne Atlas; Yuval Kupitz

Book Reviews

The Ecology of Coexistence, pp. 995-996

Species Diversity in Ecological Communities. Historical and Geographical Perspectives.

Robert E. Ricklefs; Dolph Schluter

Review author[s]: James H. Brown

Days in Rome and Berkeley, pp. 996-997

A Mind Always in Motion. The Autobiography of EMILIO SEGRÈ.

Emilio Segrè

Review author[s]: Giovanni Battimelli

Home Life of a Hero, pp. 997-998

The Private Lives of Albert Einstein.

Roger Highfield; Paul Carter

Review author[s]: David Cassidy

Respiratory Physiology, pp. 998-999

Oxygen Transport in Biological Systems. Modelling of Pathways from Environment to Cell.

S. Egginton; H. F. Ross

Review author[s]: Robert E. Forster II

Books Received, p. 999

Back Matter (61 pp.)

Previous Issue: New Series, Vol. 263, No. 5148, Feb. 11, 1994
Next Issue: New Series, Vol. 263, No. 5150, Feb. 25, 1994

Science, New Series, Vol. 263, No. 5150, Feb. 25, 1994

Previous Issue: New Series, Vol. 263, No. 5149, Feb. 18, 1994
Next Issue: New Series, Vol. 263, No. 5151, Mar. 4, 1994

Front Matter (22 pp.)
Editorial: Strategic Goals on an NIH Model, p. 1071

Daniel E. Koshland, Jr.

Letters

Animal Rights and Radical Politics, pp. 1073-1075

Adrian R. Morrison; Harold Herzog

Pork Barrel Funding an Embarrassment, pp. 1075-1076

George E. Laramore; Christopher Anderson

Safety in Quarks?, p. 1076

Arnold Kramish

Corrections and Clarifications: Cure of Xenografted Human Carcinomas by BR96-Doxorubicin Immunoconjugates, p. 1076
Corrections and Clarifications: Gene Future: The Promise and Perils of the New Biology, p. 1076
ScienceScope, p. 1079

Richard Stone

News and Comment

Measuring What Works in Health Care, pp. 1080+1082

Christopher Anderson

Academic Medicine's Stake in Health Care Reform, p. 1081

Eliot Marshall

Russia Seen Poised to Drop Prosecution of Chemist, pp. 1083-1084

Richard Stone

Losing Friends and Influencing Policy, p. 1084

Jon Cohen

Lane Holds to the Middle in Debate Over NSF's Future, pp. 1085-1086

Jeffrey Mervis

Phosphorus Fingered as Coral Killer, p. 1086

Maria Burke

Research News

Rewriting-and Redating-Prehistory, pp. 1087-1088

Ann Gibbons

A Glimmer of Hope for Coastal Migration, pp. 1088-1089

Lisa Busch

Iron Fertilization: A Tonic, but No Cure for the Greenhouse, pp. 1089-1090

Richard A. Kerr

Theoretical Ecology: Winning Its Spurs in the Real World, pp. 1090-1092

Anne Simon Moffat

Atom Beams Split by Gentle Persuasion, p. 1092

Robert Pool

Researchers Find New Role for Cell Cycle Proteins, p. 1093

Jean Marx

Random Samples, pp. 1094-1095

Constance Holden

Perspectives

Thinking About Prozac, pp. 1102-1103

Samuel H. Barondes

Duality of TBP, the Universal Transcription Factor, pp. 1103-1104

Kevin Struhl

Trench-Parallel Flow Beneath the Nazca Plate from Seismic Anisotropy, pp. 1105-1111

R. M. Russo; P. G. Silver

Reports

Spatially Resolved Observation of Static Magnetic Flux States in YBa₂Cu₃O _7-δ Grain Boundary Josephson Junctions, pp. 1112-1114

G. M. Fischer; B. Mayer; R. Gross; T. Nissel; K.-D. Husemann; R. P. Huebener; T. Freltoft; Y. Shen; P. Vase

Making Ceramics "Ductile", pp. 1114-1116

Brian R. Lawn; Nitin P. Padture; Hongda Cai; Fernando Guiberteau

Double Seismic Zone for Deep Earthquakes in the Izu-Bonin Subduction Zone, pp. 1116-1118

Takashi Iidaka; Yoshitsugu Furukawa

Age of the Earliest Known Hominids in Java, Indonesia, pp. 1118-1121

C. C. Swisher; G. H. Curtis; T. Jacob; A. G. Getty; A. Suprijo; Widiasmoro

A Molecular Organic Carbon Isotope Record of Miocene Climate Changes, pp. 1122-1125

M. Schoell; S. Schouten; J. S. Sinninghe Damsté; J. W. de Leeuw; R. E. Summons

Deep, Zonal Subequatorial Currents, pp. 1125-1128

Lynne D. Talley; Gregory C. Johnson

Extension of Life-Span by Overexpression of Superoxide Dismutase and Catalase in Drosophila melanogaster, pp. 1128-1130

William C. Orr; Rajindar S. Sohal

Requirement for CD8 β Chain in Positive Selection of CD8-Lineage T Cells, pp. 1131-1133

Kei-ichi Nakayama; Keiko Nakayama; Izumi Negishi; Keisuke Kuida; Marjorie C. Louie; Osami Kanagawa; Hiromitsu Nakauchi; Dennis Y. Loh

Persistence of Transients in Spatially Structured Ecological Models, pp. 1133-1136

Alan Hastings; Kevin Higgins

Sequential Interactions of the TCR with Two Distinct Cytoplasmic Tyrosine Kinases, pp. 1136-1139

Makio Iwashima; Bryan A. Irving; Nicolai S. C. van Oers; Andrew C. Chan; Arthur Weiss

T Cell Deletion in High Antigen Dose Therapy of Autoimmune Encephalomyelitis, pp. 1139-1143

Jeffrey M. Critchfield; Michael K. Racke; Juan Carlos Zúñiga-Pflücker; Barbara Cannella; Cedric S. Raine; Joan Goverman; Michael J. Lenardo

Premature p34 ^cdc2 Activation Required for Apoptosis, pp. 1143-1145

Lianfa Shi; Walter K. Nishioka; John Th'ng; E. Morton Bradbury; David W. Litchfield; Arnold H. Greenberg

Protein-Protein Interactions Contributing to the Specificity of Intracellular Vesicular Trafficking, pp. 1146-1149

Nicole Calakos; Mark K. Bennett; Karen E. Peterson; Richard H. Scheller

Replacement of Diseased Mouse Liver by Hepatic Cell Transplantation, pp. 1149-1152

Jonathan A. Rhim; Eric P. Sandgren; Jay L. Degen; Richard D. Palmiter; Ralph L. Brinster

Phosphorylation of the Transcription Factor PHO4 by a Cyclin-CDK Complex, PHO80-PHO85, pp. 1153-1156

Arie Kaffman; Ira Herskowitz; Robert Tjian; Erin K. O'Shea

Technical Comments

Gene Flow or Heterozygote Advantage?, pp. 1157-1158

David Berrigan; Jay Evans; David Holway; Lucia Jacobs; Miriam Richards; Jon Seger; Laurent Keller; Kenneth G. Ross; D. K. Schwartz; R. Viswanathan; J. A. Zasadzinski

Examining Langmuir-Blodgett Films with Atomic Force Microscopy, pp. 1158-1159

L. Bourdieu; O. Ronsin; D. Chatenay

Book Reviews

Widespread Likings, pp. 1161-1162

The Biophilia Hypothesis.

Stephen R. Kellert; Edward O. Wilson

Review author[s]: Claude S. Fischer

Atomic Science, pp. 1162-1163

Critical Assembly. A Technical History of Los Alamos During the Oppenheimer Years, 1943-1945.

Lillian Hoddeson; Paul W. Henriksen; Roger A. Meade; Catherine Westfall; Gordon Baym

Review author[s]: Rudolf Peierls

Protecting Plants, pp. 1163-1164

Biotechnology in Plant Disease Control.

Ilan Chet

Review author[s]: Neal K. Van Alfen

Growth and Division, pp. 1164-1165

The Cell Cycle. An Introduction.

Andrew Murray; Tim Hunt

Review author[s]: Frederick R. Cross; Kristi Levine

Books Received, p. 1165

Inside AAAS, pp. 1168-1169

Diana Pabst

Back Matter (23 pp.)

Previous Issue: New Series, Vol. 263, No. 5149, Feb. 18, 1994
Next Issue: New Series, Vol. 263, No. 5151, Mar. 4, 1994

Science, New Series, Vol. 263, No. 5151, Mar. 4, 1994

Previous Issue: New Series, Vol. 263, No. 5150, Feb. 25, 1994
Next Issue: New Series, Vol. 263, No. 5152, Mar. 11, 1994

Front Matter (27 pp.)
Editorial: Science, Technology, and Congress, p. 1203

Philip H. Abelson

Letters

Volunteers and the NBS, p. 1205

Terry L. Root; Peter Alpert

Research on Chemical Demilitarization, pp. 1205-1206

Joseph F. Bunnett

Lung Cancer Risk for Female Smokers, pp. 1206-1208

Harvey A. Risch; Geoffrey R. Howe; Meera Jain; J. David Burch; Eric J. Holowaty; Anthony B. Miller

Indirect Costs of Pesticide Use, p. 1208

Petr Karlovsky

ScienceScope, p. 1211

Richard Stone

News and Comment

NIH Tunes Up Peer Review, pp. 1212-1213

Eliot Marshall

The Window of Opportunity Is Closing Fast at CERN, pp. 1214-1215

Robert P. Crease

U. K. Panel Floats a Plan, p. 1215

Sharon Kingman

KAON Out, Space Station Squeezed, p. 1216

Douglas Powell

Panel Backs Pregnant Women in Trials, p. 1216

Christopher Anderson

Chronobiologists Out of Sync Over Light Therapy Patents, pp. 1217-1218

Rachel Nowak

Program Gives Some States a Head Start in Bid for Grants, pp. 1218-1219

Richard Stone

Random Samples, p. 1220

Constance Holden

Research News

Molecular Imprints Make a Mark, pp. 1221-1222

Faye Flam

A Game of Molecular Tennis, Anyone?, pp. 1222-1223

David Bradley

Dialing Up Undersea Data-Long Distance, pp. 1223-1224

John Travis

AAAs Provides Its Own San Francisco Quake, pp. 1225-1227

Marcia Barinaga; Jon Cohen; Faye Flam; Christine Mlot

Policy Forum

Active Intervention and Conservation: Africa's Pachyderm Problem, pp. 1241-1242

Joel Berger; Carol Cunningham

Perspectives

Fires, Atmospheric Chemistry, and the Ozone Layer, pp. 1243-1244

Ralph J. Cicerone

Precise Development from Imprecise Rules, pp. 1244-1245

Michael P. Stryker

Paleomagnetic Tests of Pacific Plate Reconstructions and Implications for Motion Between Hotspots, pp. 1246-1254

Gary D. Acton; Richard G. Gordon

Reports

Emission of Methyl Bromide from Biomass Burning, pp. 1255-1257

Stein Manö; Meinrat O. Andreae

Retention of Solar Helium and Neon in IDPs in Deep Sea Sediment, pp. 1257-1259

Hajime Hiyagon

Superconducting Mercury-Based Cuprate Films with a Zero-Resistance Transition Temperature of 124 Kelvin, pp. 1259-1261

C. C. Tsuei; A. Gupta; G. Trafas; D. Mitzi

Atomic Force Microscopy of the Electrochemical Nucleation and Growth of Molecular Crystals, pp. 1261-1264

Andrew C. Hillier; Michael D. Ward

Crystal and Molecular Structures of Rhenium Heptafluoride, pp. 1265-1267

T. Vogt; A. N. Fitch; J. K. Cockcroft

Encapsulation of Methane and Other Small Molecules in a Self-Assembling Superstructure, pp. 1267-1268

N. Branda; R. Wyler; J. Rebek, Jr.

Selection of Guide Sequences That Direct Efficient Cleavage of mRNA by Human Ribonuclease P, pp. 1269-1273

Yan Yuan; Sidney Altman

Heat-Inducible Degron: A Method for Constructing Temperature-Sensitive Mutants, pp. 1273-1276

R. Jürgen Dohmen; Peipei Wu; Alexander Varshavsky

Open "Back Door" in a Molecular Dynamics Simulation of Acetylcholinesterase, pp. 1276-1278

M. K. Gilson; T. P. Straatsma; J. A. McCammon; D. R. Ripoll; C. H. Faerman; P. H. Axelsen; I. Silman; J. L. Sussman

Suppression of Ras-Induced Transformation of NIH 3T3 Cells by Activated Gα_s, pp. 1278-1281

Jianghao Chen; Ravi Iyengar

Fusion of a Kinase Gene, ALK, to a Nucleolar Protein Gene, NPM, in Non-Hodgkin's Lymphoma, pp. 1281-1284

Stephan W. Morris; Mark N. Kirstein; Marcus B. Valentine; Kristopher G. Dittmer; David N. Shapiro; David L. Saltman; A. Thomas Look

Diversity of Endogenous Epitopes Bound to MHC Class II Molecules Limited by Invariant Chain, pp. 1284-1286

Helen Bodmer; Stéphane Viville; Christophe Benoist; Diane Mathis

Modulation of Cortical Motor Output Maps During Development of Implicit and Explicit Knowledge, pp. 1287-1289

Alvaro Pascual-Leone; Jordan Grafman; Mark Hallett

Neuronal Plasticity that Underlies Improvement in Perceptual Performance, pp. 1289-1292

Ehud Zohary; Simona Celebrini; Kenneth H. Britten; William T. Newsome

Global Form and Singularity: Modeling the Blind Spot's Role in Lateral Geniculate Morphogenesis, pp. 1292-1294

Daeyeol Lee; Joseph G. Malpeli

Technical Comments

Measuring Synaptic Interactions, pp. 1295-1297

E. E. Fetz; L. E. Shupe; A. P. Georgopoulos; M. Taira; A. V. Lukashin

Book Reviews

The Entrepreneurial Twist, p. 1299

The Billion-Dollar Molecule. One Company's Quest for the Perfect Drug.

Barry Werth

Review author[s]: Sandra Panem

Genomic Odyssey, pp. 1299-1300

Travelling Around the Human Genome. An In situ Investigation.

Bertrand Jordan

Voyage Autour du Génome. Le Tour du Monde en 80 Labos.

Bertrand Jordan

Review author[s]: Ian W. Craig

The Structure of Memory, pp. 1300-1302

Memory, Amnesia, and the Hippocampal System.

Neal J. Cohen; Howard Eichenbaum

Review author[s]: Daniel P. Kimble

Promising Polymers, pp. 1302-1303

Liquid Crystalline Polymers.

A. M. Donald; A. H. Windle

Review author[s]: Samuel I. Stupp

Correction and Updating: Home Life of a Hero, p. 1303

Books Received, p. 1303

Back Matter (41 pp.)

Previous Issue: New Series, Vol. 263, No. 5150, Feb. 25, 1994
Next Issue: New Series, Vol. 263, No. 5152, Mar. 11, 1994

Science, New Series, Vol. 263, No. 5152, Mar. 11, 1994

Previous Issue: New Series, Vol. 263, No. 5151, Mar. 4, 1994
Next Issue: New Series, Vol. 263, No. 5153, Mar. 18, 1994

Front Matter (45 pp.)
Editorial: Women in Science, p. 1355

Daniel E. Koshland Jr.

Letters

Women in Biomedicine: Encouragement, pp. 1357-1358

Sharon R. Long; Virginia Zakian

Shamans and Patent Lawyers, p. 1358

Philip L. Bereano

Corrections and Clarifications: NIH Biodiversity Grants Could Benefit Shamans, p. 1359
Corrections and Clarifications: New Test Catches Drug-Resistant TB in the Spotlight, p. 1359
Corrections and Clarifications: Boning Up: Newly Isolated Proteins Heal Bad Breaks, p. 1359
Corrections and Clarifications: Lack of Acidification in Mycobacterium Phagosomes Produced by Exclusion of the Vesicular Proton-ATPase, p. 1359
ScienceScope, p. 1363

Richard Stone

News and Comment

New AIDS Chief Takes Charge, pp. 1364-1366

Jon Cohen

LIGO Director Out in Shakeup, p. 1366

Christopher Anderson

A Bold New Program at Berkeley Runs Into Trouble, pp. 1367-1368

Marcia Barinaga

Biosphere 2 Makes a New Bid for Scientific Credibility, pp. 1368-1369

Tim Appenzeller

Random Samples, p. 1370

Constance Holden

Research News

Testing an Ancient Impact's Punch, pp. 1371-1372

Richard A. Kerr

Taking a First Look at a Tyrosine Phosphatase, p. 1373

Jean Marx

Slow DNA Repair Implicated in Mutations Found in Tumors, p. 1374

Robert Service

War of Words Continues in Violence Research, p. 1375

Charles C. Mann

Heisenberg's Heirs Exploit Loopholes in His Law, pp. 1376-1377

Gary Taubes

Policy Forums

Status and Prospects of Women in Science in Europe, pp. 1389-1391

Mary Osborn

Interventions to Increase the Participation of Women in Physics, pp. 1392-1393

Mildred S. Dresselhaus; Judy R. Franz; Bunny C. Clark

Perspectives

The Quantum Optical Repeater, pp. 1394-1395

Yoshihisa Yamamoto

Will Transgenic Crops Generate New Viruses and New Diseases?, pp. 1395-1396

Bryce W. Falk; George Bruening

Research Articles

Crystal Structure of Human Protein Tyrosine Phosphatase 1B, pp. 1397-1404

David Barford; Andrew J. Flint; Nicholas K. Tonks

The 2.9 A Crystal Structure of T. thermophilus Seryl-tRNA Synthetase Complexed with tRNA ^Ser, pp. 1404-1410

Valérie Biou; Anna Yaremchuk; Michael Tukalo; Stephen Cusack

Reports

Chain Pullout and Mobility Effects in Friction and Lubrication, pp. 1411-1413

H. R. Brown

Differential Adhesion of Cells to Enantiomorphous Crystal Surfaces, pp. 1413-1416

Dorit Hanein; Benjamin Geiger; Lia Addadi

Direct Observation of Microscopic Inhomogeneities with Energy-Dispersive Diffraction of Synchrotron-Produced X-rays, pp. 1416-1418

E. F. Skelton; A. R. Drews; M. S. Osofsky; S. B. Qadri; J. Z. Hu; T. A. Vanderah; J. L. Peng; R. L. Greene

Cytosolic pH Gradients Associated with Tip Growth, pp. 1419-1421

Bryan C. Gibbon; Darryl L. Kropf

Cell Fate Determination by the Cell Wall in Early Fucus Development, pp. 1421-1423

Frederic Berger; Alison Taylor; Colin Brownlee

Recombination Between Viral RNA and Transgenic Plant Transcripts, pp. 1423-1425

Ann E. Greene; Richard F. Allison

High-Resolution Molecular Discrimination by RNA, pp. 1425-1429

Robert D. Jenison; Stanley C. Gill; Arthur Pardi; Barry Polisky

Channel-Like Function of the Na,K Pump Probed at Microsecond Resolution in Giant Membrane Patches, pp. 1429-1432

Donald W. Hilgemann

Crystal Structures at 2.5 Angstrom Resolution of Seryl-tRNA Synthetase Complexed with Two Analogs of Seryl Adenylate, pp. 1432-1436

Hassan Belrhali; Anna Yaremchuk; Michael Tukalo; Kjeld Larsen; Carmen Berthet-Colominas; Reuben Leberman; Barbro Beijer; Brian Sproat; Jens Als-Nielsen; Gerhard Grübel; Jean-François Legrand; Mogens Lehmann; Stephen Cusack

Slow Repair of Pyrimidine Dimers at p53 Mutation Hotspots in Skin Cancer, pp. 1436-1438

Silvia Tornaletti; Gerd P. Pfeifer

DNA Repair Rates Mapped Along the Human PGK1 Gene at Nucleotide Resolution, pp. 1438-1440

Shuwei Gao; Régen Drouin; Gerald P. Holmquist

Coding of Hemolysins Within the Ribosomal RNA Repeat on A Plasmid in Entamoeba histolytica, pp. 1440-1443

Åslög Jansson; Frances Gillin; Ulrika Kagardt; Per Hagblom

Regulation of Melanin Biosynthesis in the Human Epidermis by Tetrahydrobiopterin, pp. 1444-1446

Karin U. Schallreuter; John M. Wood; Mark R. Pittelkow; Markus Gütlich; K. Regina Lemke; Wolfgang Rödl; Norma N. Swanson; Karen Hitzemann; Irmgard Ziegler

Dependence on p75 for Innervation of Some Sympathetic Targets, pp. 1447-1449

Kuo-Fen Lee; Kathy Bachman; Story Landis; Rudolf Jaenisch

Autonomy and Nonautonomy in Cell Fate Specification of Muscle in the Caenorhabditis elegans Embryo: A Reciprocal Induction, pp. 1449-1452

Ralf Schnabel

Functional Participation of the IL-2 Receptor γ Chain in IL-7 Receptor Complexes, pp. 1453-1454

Motonari Kondo; Toshikazu Takeshita; Masaya Higuchi; Masataka Nakamura; Tetsuo Sudo; Shin-Ichi Nishikawa; Kazuo Sugamura

Book Reviews

Cosmological Quest, pp. 1455-1456

Wrinkles in Time.

George Smoot; Keay Davidson

Ripples in the Cosmos. A View Behind the Scenes of the New Cosmology.

Michael Rowan-Robinson

Review author[s]: William H. Press

Anatomy of Addiction, pp. 1456-1457

Biological Basis of Substance Abuse.

Stanley G. Korenman; Jack D. Barchas

Review author[s]: Ellen M. Unterwald

Women in Science: Some Books of the Year, pp. 1458-1459

A Matter of Choices. Memoirs of a Female Physicist.

Fay Ajzenberg-Selove

Women in Chemistry and Physics. A Biobibliographic Sourcebook.

Louise S. Grinstein; Rose K. Rose; Miriam H. Rafailovich

Women Physiologists. An Anniversary Celebration of Their Contributions to British Physiology.

Lynn Bindman; Alison Brading; Tilli Tansey

The History of Women and Science, Health, and Technology. A Bibliographic Guide to the Professions and the Disciplines.

Phyllis Holman; Rima D. Apple

History of Women in Science for Young People.

Vivian Sheldon Epstein

Review author[s]: Katherine Livingston

Books Received, pp. 1459-1460

Women in Science '94: Comparisons Across Cultures

[Introduction], p. 1467

John Beditt

Surprises Across the Cultural Divide, pp. 1468-1469+1472

Marcia Barinaga

Germany: The Backbreaking Work of Scientist-Homemakers, pp. 1475-1477+1480

Peter Aldhous

Italy: Warm Climate for Women on the Mediterranean, pp. 1480-1481

Faye Flam

Sweden: Leveling the Playing Field in Stockholm, p. 1482

Peter Aldhous

Turkey: A Prominent Role on a Stage Set by History, pp. 1487-1488

Patricia Kahn

The Philippines: Fighting the Patriarchy in Growing Numbers, pp. 1491-1492

Marites D. Vitug

India: Is Overcoming 'Diffidence' the Route to Success?, pp. 1495-1496

Kalpana Sharma

Back Matter (36 pp.)

Previous Issue: New Series, Vol. 263, No. 5151, Mar. 4, 1994
Next Issue: New Series, Vol. 263, No. 5153, Mar. 18, 1994

Science, New Series, Vol. 263, No. 5153, Mar. 18, 1994

Previous Issue: New Series, Vol. 263, No. 5152, Mar. 11, 1994
Next Issue: New Series, Vol. 263, No. 5154, Mar. 25, 1994

Front Matter (15 pp.)
Editorial: Need for Enhanced Nuclear Safeguards, p. 1543

Philip H. Abelson

Letters

Reacting to Gasoline Additives, p. 1545

John P. Middaugh

Is Dioxin a Human Carcinogen? (Continued), pp. 1545-1546

Stephen S. Sternberg

Cell Transplantation and Research Design, p. 1546

David L. Felten

An Inclusive Budget Process, p. 1548

David Lightfoot

Superconductor Radiation Damage After Doping, pp. 1548-1549

R. L. Fleischer; Gary Taubes

ScienceScope, p. 1551

Richard Stone

News and Comment

French Gene Mappers at Crossroads, pp. 1552-1554

Peter Aldhous

Nicotine Scrutinized as FDA Seeks to Regulate Cigarettes, pp. 1555-1556

Rachel Nowak

Professor Slams MIT Over Center Closure, p. 1556

John Travis

India Expands Electronic Research Network, pp. 1557-1558

Bhupesh Mangla

Public Health Agency Shakeup Opposed, p. 1558

Michael Simm

Research News

Stalking the Start of Colon Cancer, pp. 1559-1560

Robert F. Service

Fire Ants Parlay Their Queens Into a Threat to Biodiversity, pp. 1560-1561

Charles C. Mann

Did Pinatubo Send Climate-Warming Gases Into a Dither?, p. 1562

Richard A. Kerr

Molecule Makers Learn the Rules of a Crooked Game, pp. 1563-1564

Faye Flam

'Long PCR' Leaps Into Larger DNA Sequences, pp. 1564-1565

Jon Cohen

Random Samples, pp. 1566-1567

Constance Holden

Perspectives

Spatiotemporal Chaos, pp. 1569-1570

M. C. Cross; P. C. Hohenberg

Time Is the Essence: Molecular Analysis of the Biological Clock, pp. 1570-1572

Terry L. Page

Why Snakes Have Forked Tongues, pp. 1573-1577

Kurt Schwenk

Research Article

Negative Feedback Defining a Circadian Clock: Autoregulation of the Clock Gene Frequency, pp. 1578-1584

Benjamin D. Aronson; Keith A. Johnson; Jennifer J. Loros; Jay C. Dunlap

Reports

5-Coordinate Si Compounds as Intermediates in the Synthesis of Silicates in Nonaqueous Media, pp. 1585-1587

Bruno Herreros; Stuart W. Carr; Jacek Klinowski

Recent Changes in Atmospheric Carbon Monoxide, pp. 1587-1590

Paul C. Novelli; Ken A. Masarie; Pieter P. Tans; Patricia M. Lang

Sound Velocities in Dense Hydrogen and the Interior of Jupiter, pp. 1590-1593

Thomas S. Duffy; Willem L. Vos; Chang-Sheng Zha; Russell J. Hemley; Ho-Kwang Mao

Short-Lived Chemical Heterogeneities in the Archean Mantle with Implications for Mantle Convection, pp. 1593-1596

Janne Blichert-Toft; Francis Albarède

Growth of Diamond from Atomic Hydrogen and a Supersonic Free Jet of Methyl Radicals, pp. 1596-1598

Szetsen Steven Lee; David W. Minsek; Daniel J. Vestyck; Peter Chen

An in Vitro System for Adhesion and Fusion of Maize Gametes, pp. 1598-1600

J.-E. Faure; C. Digonnet; C. Dumas

Biodegradable Long-Circulating Polymeric Nanospheres, pp. 1600-1603

Ruxandra Gref; Yoshiharu Minamitake; Maria Teresa Peracchia; Vladimir Trubetskoy; Vladimir Torchilin; Robert Langer

Loss of Circadian Behavioral Rhythms and per RNA Oscillations in the Drosophila Mutant timeless, pp. 1603-1606

Amita Sehgal; Jeffrey L. Price; Bernice Man; Michael W. Young

Block in Nuclear Localization of period Protein by a Second Clock Mutation, timeless, pp. 1606-1609

Leslie B. Vosshall; Jeffrey L. Price; Amita Sehgal; Lino Saez; Michael W. Young

Activation of Phosphatidylinositol-3′ Kinase by Src-Family Kinase SH3 Binding to the p85 Subunit, pp. 1609-1612

Christopher M. Pleiman; W. Marc Hertz; John C. Cambier

Requirement for Transcription Factor IRF-1 in NO Synthase Induction in Macrophages, pp. 1612-1615

R. Kamijo; H. Harada; T. Matsuyama; M. Bosland; J. Gerecitano; D. Shapiro; J. Le; S. I. Koh; T. Kimura; S. J. Green; T. W. Mak; T. Taniguchi; J. Vilček

Positive and Negative Thymocyte Selection Induced by Different Concentrations of a Single Peptide, pp. 1615-1618

Eric Sebzda; Valerie A. Wallace; John Mayer; Rae S. M. Yeung; Tak W. Mak; Pamela S. Ohashi

Requirement for BDNF in Activity-Dependent Survival of Cortical Neurons, pp. 1618-1623

Anirvan Ghosh; Josette Carnahan; Michael E. Greenberg

Long-Range Cis Preference in DNA Homology Search Over the Length of a Drosophila Chromosome, pp. 1623-1625

William R. Engels; Christine R. Preston; Dena M. Johnson-Schlitz

Mutation of a mutL Homolog in Hereditary Colon Cancer, pp. 1625-1629

Nickolas Papadopoulos; Nicholas C. Nicolaides; Ying-Fei Wei; Steven M. Ruben; Kenneth C. Carter; Craig A. Rosen; William A. Haseltine; Robert D. Fleischmann; Claire M. Fraser; Mark D. Adams; J. Craig Venter; Stanley R. Hamilton; Gloria M. Petersen; Patrice Watson; Henry T. Lynch; Päivi Peltomäki; Jukka-Pekka Mecklin; Albert de la Chapelle; Kenneth W. Kinzler; Bert Vogelstein

Coatomer Interaction with Di-Lysine Endoplasmic Reticulum Retention Motifs, pp. 1629-1631

Pierre Cosson; François Letourneur

Book Reviews

The Swedish Scene, pp. 1633-1635

Center on the Periphery. Historical Aspects of 20th-Century Swedish Physics.

Svante Lindqvist; Marika Hedin; Thomas Kaiserfeld

Review author[s]: Finn Aaserud

Psychology via Physiology, pp. 1635-1636

The Neuroscience of Animal Intelligence. From the Seahare to the Seahorse.

Euan M. Macphail

Review author[s]: M. E. Bitterman

Living Landscapes, pp. 1636-1637

The Desert's Past. A Natural Prehistory of the Great Basin.

Donald K. Grayson

Review author[s]: David P. Adam

Books Received, p. 1637

Back Matter (19 pp.)

Previous Issue: New Series, Vol. 263, No. 5152, Mar. 11, 1994
Next Issue: New Series, Vol. 263, No. 5154, Mar. 25, 1994

Science, New Series, Vol. 263, No. 5154, Mar. 25, 1994

Previous Issue: New Series, Vol. 263, No. 5153, Mar. 18, 1994
Next Issue: New Series, Vol. 264, No. 5155, Apr. 1, 1994

Front Matter (28 pp.)
Editorial: Materials Science, p. 1667

John I. Brauman

Letters

Renovating Italian Science, p. 1669

Donato Romagnolo; Ornella Selmin

Quality of EPA Research, pp. 1669-1670

Michael W. Golay; Henry I. Miller; Richard N. L. Andrews

Memoires of Uranium, p. 1670

Malcolm C. Bourne

The Odds of Retirement, pp. 1670-1671

Stephen M. Stigler

Corrections and Clarifications: Learning How to Suppress Cancer, p. 1671
ScienceScope, p. 1675

Christopher Anderson

News and Comment

Defense Conversion Comes to Campus, pp. 1676-1678

Jeffrey Mervis

Report Calls for Smaller Clinical Center, p. 1678

Jon Cohen

How Not to Publicize a Misconduct Finding, p. 1679

Christopher Anderson

Two New Graduate Schools Break the Japanese Mold, pp. 1680-1681

Dennis Normile

A New Problem: Too Much Money, p. 1681

Christopher Anderson

Research News

Microwave Mappers Sweat Details, pp. 1682-1684

Gary Taubes

Cosmic Structures Fill Southern Sky, p. 1684

John Travis

IL-12 Holds Promise Against Cancer, Glimmer of AIDS Hope, pp. 1685-1686

Stephen S. Hall

Mummy Settles TB Antiquity Debate, pp. 1686-1687

Virginia Morell

Random Samples, pp. 1688-1689

Constance Holden

Materials Science

News

The Smallest Chemical Plants, pp. 1698-1699

Robert Pool

After Years in the Dark, Electric Plastic Finally Shines, pp. 1700-1702

Daniel Clery

Building Bridges to the Nanoworld, pp. 1702-1703

John Travis

Perspectives

Computer Simulations of Fracture at the Atomic Level, pp. 1704-1705

Ruth M. Lynden-Bell

Nonlinear Optical Polymers: Discovery to Market in 10 Years?, pp. 1706-1707

Seth R. Marder; Joseph W. Perry

Metallic Corrosion, pp. 1708-1709

Roger C. Newman; Karl Sieradzki

Functional Polymers and Dendrimers: Reactivity, Molecular Architecture, and Interfacial Energy, pp. 1710-1715

Jean M. J. Fréchet

New Challenges in Biomaterials, pp. 1715-1720

Nicholas A. Peppas; Robert Langer

Adhesion: Molecules and Mechanics, pp. 1720-1725

Kevin Kendall

Langmuir-Blodgett Films, pp. 1726-1733

J. A. Zasadzinski; R. Viswanthan; L. Madsen; J. Garnaes; D. K. Schwartz

Reports

Following Ion Diffusion in Solution, pp. 1739-1741

S. Rondot; J. Cazaux; O. Aaboubi; J. P. Chopart; A. Olivier

From Static to Kinetic Friction in Confined Liquid Films, pp. 1741-1744

Günter Reiter; A. Levent Demirel; Steve Granick

Defects in Carbon Nanostructures, pp. 1744-1747

O. Zhou; R. M. Fleming; D. W. Murphy; C. H. Chen; R. C. Haddon; A. P. Ramirez; S. H. Glarum

Changes in Atmospheric Circulation and Ocean Ice Cover over the North Atlantic During the Last 41,000 Years, pp. 1747-1751

P. A. Mayewski; L. D. Meeker; S. Whitlow; M. S. Twickler; M. C. Morrison; P. Bloomfield; G. C. Bond; R. B. Alley; A. J. Gow; P. M. Grootes; D. A. Meese; M. Ram; K. C. Taylor; W. Wumkes

Gallium Arsenide Transistors: Realization Through a Molecularly Designed Insulator, pp. 1751-1753

Phillip P. Jenkins; Andrew N. MacInnes; Massood Tabib-Azar; Andrew R. Barron

Diamond Coating of Titanium Alloys, pp. 1753-1755

M. D. Drory; J. W. Hutchinson

The Drosophila saxophone Gene: A Serine-Threonine Kinase Receptor of the TGF-β Superfamily, pp. 1756-1759

Ting Xie; Alyce L. Finelli; Richard W. Padgett

Protection from Fas-Mediated Apoptosis by a Soluble Form of the Fas Molecule, pp. 1759-1762

Jianhua Cheng; Tong Zhou; Changdan Liu; John P. Shapiro; Matthew J. Brauer; Michael C. Kiefer; Philip J. Barr; John D. Mountz

High-Resolution Solution Structure of the β Chemokine hMIP-1β by Multidimensional NMR, pp. 1762-1767

Patricia J. Lodi; Daniel S. Garrett; John Kuszewski; Monica L.-S. Tsang; James A. Weatherbee; Warren J. Leonard; Angela M. Gronenborn; G. Marius Clore

Direct Signaling from Astrocytes to Neurons in Cultures of Mammalian Brain Cells, pp. 1768-1771

Maiken Nedergaard

Genetic Mapping of Quantitative Trait Loci for Growth and Fatness in Pigs, pp. 1771-1774

Leif Andersson; Chris S. Haley; Hans Ellegren; Sara A. Knott; Maria Johansson; Kjell Andersson; Lena Andersson-Eklund; Inter Edfors-Lilja; Marete Fredholm; Ingemar Hansson; Jan Håkansson; Kerstin Lundström

A Subset of CD4⁺ Thymocytes Selected by MHC Class I Molecules, pp. 1774-1778

Albert Bendelac; Nigel Killeen; Dan R. Littman; Ronald H. Schwartz

Book Reviews

Craniology: Getting a Head, pp. 1779-1780

The Skull: Vol. 1, Development.

James Hanken; Brian K. Hall

The Skull: Vol. 2, Patterns of Structural and Systematic Diversity.

James Hanken; Brian K. Hall

The Skull: Vol. 3, Functional and Evolutionary Mechanisms.

James Hanken; Brian K. Hall

Review author[s]: Kurt Schwenk

Visual Recognition, pp. 1780-1781

Selective Attention in Vision.

A. H. C. van der Heijden

Review author[s]: James E. Hoffman

Autonomous Systems, pp. 1781-1782

Intelligent Behavior in Animals and Robots.

David McFarland; Thomas Bösser

Review author[s]: Randall D. Beer

Quantitative Cell Biology, p. 1782

Receptors. Models for Binding, Trafficking, and Signaling.

Douglas A. Lauffenburger; Jennifer J. Linderman

Review author[s]: Alan L. Schwartz

Books Received, pp. 1782-1783

Inside AAAS, p. 1785

Diana Pabst

Back Matter (19 pp.)

Previous Issue: New Series, Vol. 263, No. 5153, Mar. 18, 1994
Next Issue: New Series, Vol. 264, No. 5155, Apr. 1, 1994

Science, New Series, Vol. 264, No. 5155, Apr. 1, 1994

Previous Issue: New Series, Vol. 263, No. 5154, Mar. 25, 1994
Next Issue: New Series, Vol. 264, No. 5156, Apr. 8, 1994

Volume Information (11 pp.)
Front Matter (24 pp.)
Editorial: A Milk-Free Zone, p. 11

Daniel E. Koshland, Jr.

Letters

Colon Cancer Screening, pp. 13-14

David M. Danks; Francis S. Collins

Plutonium's Existence, p. 14

C. R. Richmond

Fusion Confusion, pp. 14-15

Rolf M. Sinclair

Beef Quality, p. 15

Michael L. Thonney

Future Energy Supplies, pp. 15-16

Mary E. Clark; Philip S. Brumbaugh

Consciousness: In Whose Hands?, p. 16

John W. Fowler

Corrections and Clarifications: p53 Sweeps Through Cancer Research, p. 16
Corrections and Clarifications: Dynamics of the Hippocampal Ensemble Code for Space, p. 16
Corrections and Clarifications: Selective and ATP-Dependent Translocation of Peptides by the MHC-Encoded Peptide Transporter, p. 16
ScienceScope, p. 19

Richard Stone

News and Comment

An Anthropological Culture Shift, pp. 20-22

Virginia Morell

Young Physicists Hear Wall Street Calling, p. 22

Gary Taubes

Richard Leakey Quits Post, Charges 'Smear Campaign', p. 23

Virginia Morell

Model Programs Take Aim at HIV Rates in Indonesia, pp. 24-25

Jane E. Stevens

NASA Told Belt-Tightening Won't Work, p. 25

Christopher Anderson

Random Samples, pp. 26-27

Constance Holden

Research News

A Dusty Road for Space Physics, pp. 28-30

James Glanz

Study Implicates Second-Hand Smoke, p. 30

Richard Stone

New Cell Transplants May Mend a Broken Heart, p. 31

Rachel Nowak

Chemists Get a Taste of Life At Gathering in San Diego, pp. 32-33

Faye Flam

'Lucy,' Crucial Early Human Ancestor, Finally Gets a Head, pp. 34-35

James Shreeve

An Asteroidal Family Adds a Little One, p. 35

Richard A. Kerr

Perspective

Giant Hawaiian Underwater Landslides, pp. 46-47

James G. Moore; William R. Normark; Robin T. Holcomb

Ceramic Thin-Film Formation on Functionalized Interfaces Through Biomimetic Processing, pp. 48-55

B. C. Bunker; P. C. Rieke; B. J. Tarasevich; A. A. Campbell; G. E. Fryxell; G. L. Graff; L. Song; J. Liu; J. W. Virden; G. L. McVay

Reports

The 1990 to 1991 Sudan Earthquake Sequence and the Extent of the East African Rift System, pp. 67-70

R. W. Girdler; D. A. McConnell

El Niño on the Devil's Staircase: Annual Subharmonic Steps to Chaos, pp. 70-72

Fei-Fei Jin; J. David Neelin; Michael Ghil

El Niño Chaos: Overlapping of Resonances Between the Seasonal Cycle and the Pacific Ocean-Atmosphere Oscillator, pp. 72-74

Eli Tziperman; Lewi Stone; Mark A. Cane; Hans Jarosh

Growth of Continental-Scale Metro-Agro-Plexes, Regional Ozone Pollution, and World Food Production, pp. 74-77

W. L. Chameides; P. S. Kasibhatla; J. Yienger; H. Levy II

Unexpected Square Symmetry Seen by Atomic Force Microscopy in Bilayer Films of Disk-Like Molecules, pp. 77-79

Nicholas C. Maliszewskyj; Paul A. Heiney; Jack Y. Josefowicz; John P. McCauley Jr.; Amos B. Smith III

Effects of Boundaries on Pattern Formation: Catalytic Oxidation of CO on Platinum, pp. 80-82

M. D. Graham; Ioannis G. Kevrekidis; K. Asakura; J. Lauterbach; K. Krischer; H.-H. Rotermund; G. Ertl

Crystal Structure of the Principal Neutralization Site of HIV-1, pp. 82-85

Jayant B. Ghiara; Enrico A. Stura; Robyn L. Stanfield; Albert T. Profy; Ian A. Wilson

Structure of an Electron Transfer Complex: Methylamine Dehydrogenase, Amicyanin, and Cytochrome c _551i, pp. 86-90

Longyin Chen; Rosemary C. E. Durley; F. Scott Mathews; Victor L. Davidson

Neutrophil Activation by Monomeric Interleukin-8, pp. 90-92

Krishnakumar Rajarathnam; Brian D. Sykes; Cyril M. Kay; Beatrice Dewald; Thomas Geiser; Marco Baggiolini; Ian Clark-Lewis

Requirement of Human Renal Water Channel Aquaporin-2 for Vasopressin-Dependent Concentration of Urine, pp. 92-95

Peter M. T. Deen; Marian A. J. Verdijk; Nine V. A. M. Knoers; Bé Wieringa; Leo A. H. Monnens; Carel H. van Os; Bernard A. van Oost

Stat3: A STAT Family Member Activated by Tyrosine Phosphorylation in Response to Epidermal Growth Factor and Interleukin-6, pp. 95-98

Zhong Zhong; Zilong Wen; James E. Darnell Jr.

Formation of Nascent Intercalated Disks Between Grafted Fetal Cardiomyocytes and Host Myocardium, pp. 98-101

Mark H. Soonpaa; Gou Young Koh; Michael G. Klug; Loren J. Field

Characterization of Type I Receptors for Transforming Growth Factor-β and Activin, pp. 101-104

Peter ten Dijke; Hidetoshi Yamashita; Hidenori Ichijo; Petra Franzén; Marikki Laiho; Kohei Miyazono; Carl-Henrik Heldin

FGF-2: Apical Ectodermal Ridge Growth Signal for Chick Limb Development, pp. 104-107

John F. Fallon; Alric López; Maria A. Ros; Mary P. Savage; Bradley B. Olwin; B. Kay Simandl

Roles of N-Type and Q-Type Ca ²⁺ Channels in Supporting Hippocampal Synaptic Transmission, pp. 107-111

David B. Wheeler; Andrew Randall; Richard W. Tsien

Technical Comments

Solid Friction and Polymer Relaxation in Gel Electrophoresis, pp. 112-113

Jean-Louis Viovy; Thomas Duke; Sergei Burlatsky; John Deutch

Book Reviews

Atmospheric Interplay, p. 115

Aerosol-Cloud-Climate Interactions.

Peter V. Hobbs

Review author[s]: Richard C. J. Somerville

The Acquisition of Sex, p. 116

Molecular Genetics of Sex Determination.

Stephen S. Wachtel

Review author[s]: Lee M. Silver

Biological Patterns, pp. 116-117

Life History Invariants. Some Explorations of Symmetry in Evolutionary Biology.

Eric L. Charnov

Review author[s]: Robert E. Ricklefs

The Next Nets, pp. 117-118

The Neurobiology of Neural Networks.

Daniel Gardner

Review author[s]: Scott L. Hooper

Books Received, pp. 118-120

Back Matter (52 pp.)

Previous Issue: New Series, Vol. 263, No. 5154, Mar. 25, 1994
Next Issue: New Series, Vol. 264, No. 5156, Apr. 8, 1994

Science, New Series, Vol. 264, No. 5156, Apr. 8, 1994

Previous Issue: New Series, Vol. 264, No. 5155, Apr. 1, 1994
Next Issue: New Series, Vol. 264, No. 5157, Apr. 15, 1994

Front Matter (33 pp.)
Editorial: Chemicals: Perceptions Versus Facts, p. 183

Philip H. Abelson

Letters

Misrepresentation and Fantasy, p. 185

Robert N. Cahn; J. David Jackson; Chris Quigg

A National Institute for the Environment, p. 185

Peter D. Saundry

Adaptive Optics in Astronomy, pp. 185-186

Frederick Seitz

Space Science Crunch, pp. 186-187

Jonathan Katz; Harvey Tananbaum

National Protein and Nucleic Acid Databases, p. 187

Elinor Adman; Martin Gellert; Maimon Cohen; Norma M. Allewell; Bruce S. Baker; Joseph Villafranca

Smallpox Virus: Better to Store?, p. 187

Patrick Hess

Elephant Man's Disease, p. 188

Margaret R. Wallace; Rachel Nowak

Phonetics Lesson, p. 188

Ian Hinchliffe

Corrections and Clarifications: Picturing Nature: American Nineteenth-Century Zoological Illustration, p. 188
ScienceScope, p. 191

Richard Stone

News

The Hand on Your Purse Strings, pp. 192-194

Livermore Lab Chief Nuckolls Resigns Under Pressure, p. 195

Ellis Rubinstein

Report: All's Fair in NSF Major Awards, p. 196

John Travis

Key Study Unveiled-11 Years Late, pp. 196-197

Rachel Nowak

SIDS Paper Triggers a Murder Charge, pp. 197-198

Ginger Pinholster

Livermore Physicists Ask for the Sun, p. 198

Faye Flam

Deep-Trench Research Waits on Balky Japanese Submersible, p. 199

Dennis Normile

In Pittsburgh, Physicists Get Down to the Nitty-Gritty, pp. 200-201

Robert Service

Ecologists Dare to Ask: How Much Does Diversity Matter?, pp. 202-203

Yvonne Baskin

Trail of Toxins Leads Through Conference Rooms in Dallas, p. 204

Richard Stone

Random Samples, p. 205

Constance Holden

Special News Report

Leroy Hood: Thinking Big in Seattle, pp. 206-209

Leslie Roberts

Policy Forum

Science in the National Interest, pp. 221-222

Barbara A. Mikulski

Perspectives

Self-Organization in Living Cells, pp. 223-224

Benno Hess; Alexander Mikhailov

The Evolution of Genetic Intelligence, pp. 224-225

David S. Thaler

Modulated Magnetic Phases in Rare Earth Metallic Systems, pp. 226-231

Tapan Chattopadhyay

Research Article

Neural Mechanisms for Forming a Perceptual Decision, pp. 231-237

C. Daniel Salzman; William T. Newsome

Reports

Stellar Luminosity Variations and Global Warming, pp. 238-239

Peter Foukal

Trends in Stomatal Density and ¹³ C/ ¹² C Ratios of Pinus flexilis Needles During Last Glacial-Interglacial Cycle, pp. 239-243

P. K. Van de Water; S. W. Leavitt; J. L. Betancourt

Quantifying Global Warming from the Retreat of Glaciers, pp. 243-245

Johannes Oerlemans

Morphological Bifurcations Involving Reaction-Diffusion Processes During Microtubule Formation, pp. 245-248

James Tabony

Molecular Nanotube Aggregates of β- and γ-Cyclodextrins Linked by Diphenylhexatrienes, pp. 249-251

Guang Li; Linda B. McGown

Binding and Suppression of the Myc Transcriptional Activation Domain by p107, pp. 251-254

Wei Gu; Kishor Bhatia; Ian T. Magrath; Chi V. Dang; Riccardo Dalla-Favera

Related Target Enhancers for Dorsal and NF-κB Signaling Pathways, pp. 255-258

Sergio González-Crespo; Michael Levine

Recombination in Adaptive Mutation, pp. 258-260

Reuben S. Harris; Simonne Longerich; Susan M. Rosenberg

Isolation of S. cerevisiae snRNPs: Comparison of U1 and U4/U6.U5 to Their Human Counterparts, pp. 261-265

Patrizia Fabrizio; Sybille Esser; Berthold Kastner; Reinhard Lührmann

Mutational Isolation of a Sieve for Editing in a Transfer RNA Synthetase, pp. 265-267

Eric Schmidt; Paul Schimmel

Stimulation of Human γδ T Cells by Nonpeptidic Mycobacterial Ligands, pp. 267-270

Patricia Constant; François Davodeau; Marie-Alix Peyrat; Yannick Poquet; Germain Puzo; Marc Bonneville; Jean-Jacques Fournié

Telomere-Led Premeiotic Chromosome Movement in Fission Yeast, pp. 270-273

Yuji Chikashige; Da-Qiao Ding; Hironori Funabiki; Tokuko Haraguchi; Shinro Mashiko; Mitsuhiro Yanagida; Yasushi Hiraoka

Requirement for the Yeast Gene LON in Intramitochondrial Proteolysis and Maintenance of Respiration, pp. 273-276

Carolyn K. Suzuki; Kitaru Suda; Nan Wang; Gottfried Schatz

Soluble b-Amyloid Induction of Alzheimer's Phenotype for Human Fibroblast K⁺ Channels, pp. 276-279

René Etcheberrigaray; Etsuro Ito; Christopher S. Kim; Daniel L. Alkon

Technical Comments

High-Pressure Melting of (Mg,Fe)SiO₃-Perovskite, pp. 279-281

Dion L. Heinz; Elise Knittle; Jeffrey S. Sweeney; Quentin Williams; Raymond Jeanloz; R. Boehler; A. Zerr

Statistical Analyses of Soil Quality, pp. 281-283

David A. Wardle; J. P. Reganold

Book Reviews

Big Systems, pp. 293-294

Choosing Big Technologies.

John Krige

Review author[s]: Robert W. Smith

Thoughtplay, pp. 294-295

Games of Life. Explorations in Ecology, Evolution, and Behaviour.

Karl Sigmund

Review author[s]: Peter Yodzis

Molluscan Dwellings, pp. 295-296

A Natural History of Shells.

Geerat J. Vermeij

Review author[s]: W. Bruce Saunders

Probing Biological Surfaces, p. 296

STM and SFM in Biology.

Othmar Marti; Matthias Amrein

Review author[s]: Carlos Bustamante

Books Received, pp. 296-297

Back Matter (19 pp.)

Previous Issue: New Series, Vol. 264, No. 5155, Apr. 1, 1994
Next Issue: New Series, Vol. 264, No. 5157, Apr. 15, 1994

Science, New Series, Vol. 264, No. 5157, Apr. 15, 1994

Previous Issue: New Series, Vol. 264, No. 5156, Apr. 8, 1994
Next Issue: New Series, Vol. 264, No. 5158, Apr. 22, 1994

Front Matter (28 pp.)
Editorial: The Biological Warfare of the Future, p. 327

Daniel E. Koshland Jr.

Letters

Ice Age "Venuses", p. 329

Alexander Marshack; L. R. Caswell

The Meaning of Models, pp. 329-331

John D. Sterman; Edward J. Rykiel Jr.; Naomi Oreskes; Kenneth Belitz; Kristin Shrader-Frechette

Corrections and Clarifications: Venuses Reappear, p. 331
ScienceScope, p. 335

Richard Stone

News and Comment

Livermore Faces Forces of Change, pp. 336-338

Christopher Anderson

Rising Yen Threatens Key Cancer Study, p. 338

Eliot Marshall

ATOC Delayed as Report Laments Research Gaps, pp. 339-340

Karen Schmidt

Disparities Detailed in NCI Division, p. 340

Lisa Seachrist

'Secretary Snafu' May Cost Researchers, Universities, p. 341

Jon Cohen

Random Samples, pp. 342-343

Constance Holden

Research News

New Tumor Suppressor May Rival p53, pp. 344-345

Jean Marx

A Supergiant Dies in the Whirlpool, p. 345

Ray Jayawardhana

The Keck Scopes Out the Legacy of the Big Bang, p. 346

Ray Jayawardhana

Alaska Sites Contend as Native Americans' First Stop, p. 347

Lisa Busch

New Instruments Shed Light On Astronomy's Future, pp. 348-349

John Travis

Anthropologists Take the Measure of Humanity, pp. 350-351

Ann Gibbons

Frontiers in Biotechnology: Resistance to Antibiotics

[Introduction], p. 359

Gilbert J. Chin; Jean Marx

News Reports

Reviving the Antibiotic Miracle?, pp. 360-362

John Travis

Funding Crunch Hobbles Antibiotic Resistance Research, pp. 362-363

Elizabeth Culotta

Resistance a European Problem, Too, pp. 363+364-365

Sharon Kingman

Hungary Sees an Improvement in Penicillin Resistance, p. 364

Rachel Nowak

Search for Sepsis Drugs Goes On Despite Past Failures, pp. 365-367

Richard Stone

Policy Forum

Infectious Disease Surveillance: A Crumbling Foundation, pp. 368-370

Ruth L. Berkelman; Ralph T. Bryan; Michael T. Osterholm; James W. LeDuc; James M. Hughes

Perspectives

Human Mycoses: Drugs and Targets for Emerging Pathogens, pp. 371-373

Nafsika H. Georgopapadakou; Thomas J. Walsh

Ubiquitous Natural Antibiotics, pp. 373-374

Joelle E. Gabay

Inactivation of Antibiotics and the Dissemination of Resistance Genes, pp. 375-382

Julian Davies

Prevention of Drug Access to Bacterial Targets: Permeability Barriers and Active Efflux, pp. 382-388

Hiroshi Nikaido

Resistance to Antibiotics Mediated by Target Alterations, pp. 388-393

Brian G. Spratt

Reports

Synthesis, Isolation, and Equilibration of 1,9- and 7,8-C ₇₀ H₂, pp. 397-399

Craig C. Henderson; Celeste McMichael Rohlfing; Kenneth T. Gillen; Paul A. Cahill

A Mass Spectrometric Solution to the Address Problem of Combinatorial Libraries, pp. 399-402

Christopher L. Brummel; Irene N. W. Lee; Ying Zhou; Stephen J. Benkovic; Nicholas Winograd

Antiferromagnetic Ordering and Paramagnetic Behavior of Ferromagnetic Cu₆ and Cu ₁₈ Clusters in BaCuO _2+x, pp. 402-404

Z.-R. Wang; X.-L. Wang; J. A. Fernandez-Baca; D. C. Johnston; D. Vaknin

Temperatures in Earth's Core Based on Melting and Phase Transformation Experiments on Iron, pp. 405-407

S. K. Saxena; G. Shen; P. Lazor

Topographic Forcing of the Atmosphere and a Rapid Change in the Length of Day, pp. 407-409

David A. Salstein; Richard D. Rosen

Anisotropy and Coherent Vortex Structures in Planetary Turbulence, pp. 410-413

James C. McWilliams; Jeffrey B. Weiss; Irad Yavneh

Thousandfold Change in Resistivity in Magnetoresistive La-Ca-Mn-O Films, pp. 413-415

S. Jin; T. H. Tiefel; M. McCormack; R. A. Fastnacht; R. Ramesh; L. H. Chen

Adhesion Forces Between Individual Ligand-Receptor Pairs, pp. 415-417

Ernst-Ludwig Florin; Vincent T. Moy; Hermann E. Gaub

Structure of the Tet Repressor-Tetracycline Complex and Regulation of Antibiotic Resistance, pp. 418-420

Winfried Hinrichs; Caroline Kisker; Martina Düvel; Alexander Müller; Karlheinz Tovar; Wolfgang Hillen; Wolfram Saenger

Stomatal Size in Fossil Plants: Evidence for Polyploidy in Majority of Angiosperms, pp. 421-424

Jane Masterson

Differential Complementation of Bcr-Abl Point Mutants with c-Myc, pp. 424-426

Daniel E. H. Afar; Andrei Goga; Jami McLaughlin; Owen N. Witte; Charles L. Sawyers

A Dual Embryonic Origin for Vertebrate Mechanoreceptors, pp. 426-430

Andres Collazo; Scott E. Fraser; Paula M. Mabee

Association of Intestinal Peptide Transport with a Protein Related to the Cadherin Superfamily, pp. 430-433

Anne H. Dantzig; JoAnn Hoskins; Linda B. Tabas; Stuart Bright; Robert L. Shepard; Ivan L. Jenkins; Dale C. Duckworth; J. Richard Sportsman; Daniel Mackensen; Paul R. Rosteck, Jr.; Paul L. Skatrud

Association of Poly(CA)·Poly(TG) DNA Fragments Into Four-Stranded Complexes Bound by HMG1 and 2, pp. 433-436

Claire Gaillard; François Strauss

A Cell Cycle Regulator Potentially Involved in Genesis of Many Tumor Types, pp. 436-440

Alexander Kamb; Nelleke A. Gruis; Jane Weaver-Feldhaus; Qingyun Liu; Keith Harshman; Sean V. Tavtigian; Elisabeth Stockert; Rufus S. Day III; Bruce E. Johnson; Mark H. Skolnick

Book Reviews

Fly Culture, pp. 445-446

Lords of the Fly. Drosophila Genetics and Experimental Practice.

Robert E. Kohler

Review author[s]: Philip J. Pauly

Fatal Disharmonies, pp. 446-447

The Ghost of the Executed Engineer. Technology and the Fall of the Soviet Union.

Loren R. Graham

Review author[s]: David Holloway

A Theory of Perception, pp. 447-448

Information, Sensation, and Perception.

Kenneth H. Norwich

Review author[s]: John C. Baird

"Organic Technology", p. 448

Molecular Nonlinear Optics. Materials, Physics, and Devices.

Joseph Zyss

Review author[s]: Nicolaas Bloembergen

Books Received, pp. 448-449

Back Matter (27 pp.)

Previous Issue: New Series, Vol. 264, No. 5156, Apr. 8, 1994
Next Issue: New Series, Vol. 264, No. 5158, Apr. 22, 1994

Science, New Series, Vol. 264, No. 5158, Apr. 22, 1994

Previous Issue: New Series, Vol. 264, No. 5157, Apr. 15, 1994
Next Issue: New Series, Vol. 264, No. 5159, Apr. 29, 1994

Front Matter (37 pp.)
Editorial: Chemical Ecology, p. 487

Philip H. Abelson

Letters

Livermore Lab Head, p. 489

C. Bruce Tarter; Daniel E. Koshland, Jr.

Viral Recombination in Transgenic Plants, pp. 489-490

Margaret Mellon; Jane Rissler; George Bruening; Bryce W. Falk

Adolescent Health Study, p. 490

Duane Alexander

Proposed NSF Violence Center, p. 490

James A. Mercy

Element Naming, p. 491

E. Kenneth Hulet

Inhibition of Rev-Mediated HIV-1 Expression: Retraction, p. 492

Mel Campbell; Barbara K. Felber; Georgios Nasioulas; Elena Afonina; George N. Pavlakis

Corrections and Clarifications: Cosmic Structures Fill Southern Sky, p. 492
Corrections and Clarifications: The Aftermath of the Gallo Case, p. 492
ScienceScope, p. 495

Richard Stone

News and Comment

Dr. Alberts Comes to Washington, pp. 496-498

Jeffrey Mervis

NIH Tightens Clinical Trials Monitoring, p. 499

Lisa Seachrist

Pesticides and Breast Cancer: No Link?, pp. 499-500

Gary Taubes

Beta-Carotene: Helpful or Harmful?, pp. 500-501

Rachel Nowak

Big Science in a Developing Country, pp. 501-502

Ray Jayawardhana

Research News

Vaccines Get a New Twist, pp. 503-505

Jon Cohen

Pulsing Star Confirms More Planets in the Universe, pp. 506-507

John Travis

Gene Transfer to Spark a Failing Heart, pp. 507-508

Lisa Seachrist

A New Laser Promises to Put an End to Band Gap Slavery, pp. 508-509

Gary Taubes

Structure Meets Function at Materials Gathering, pp. 510-511

Robert F. Service

Random Samples, pp. 512-513

Constance Holden

Perspectives

Sulfate Aerosols and Polar Stratospheric Cloud Formation, pp. 527-528

Margaret A. Tolbert

The Prion Connection: Now in Yeast?, pp. 528-530

Charles Weissmann

Structural Clues to Prion Replication, pp. 530-531

Fred E. Cohen; Keh-Ming Pan; Ziwei Huang; Michael Baldwin; Robert J. Fletterick; Stanley B. Prusiner

Diet and Health: What Should We Eat?, pp. 532-537

Walter C. Willett

Research Article

Confirmation of Earth-Mass Planets Orbiting the Millisecond Pulsar PSR B1257+12, pp. 538-542

Alexander Wolszczan

Reports

Antarctic Total Ozone in 1958, pp. 543-546

Paul A. Newman

Strontium Isotopic Composition of Mid-Cretaceous Seawater, pp. 546-550

B. Lynn Ingram; Rodolfo Coccioni; Alessandro Montanari; Frank M. Richter

Origin of Saturn's E Ring: Self-Sustained, Naturally, pp. 550-553

Douglas P. Hamilton; Joseph A. Burns

Quantum Cascade Laser, pp. 553-556

Jerome Faist; Federico Capasso; Deborah L. Sivco; Carlo Sirtori; Albert L. Hutchinson; Alfred Y. Cho

A Mechanism of Lithium Storage in Disordered Carbons, pp. 556-558

Kenji Sato; Minoru Noguchi; Atsushi Demachi; Naohiko Oki; Morinobu Endo

A Putative Role of the Xanthophyll, Zeaxanthin, in Blue Light Photoreception of Corn Coleoptiles, pp. 558-561

Miguel A. Quiñones; Eduardo Zeiger

The Role of Interleukin-6 in Mucosal IgA Antibody Responses in Vivo, pp. 561-563

Alistair J. Ramsay; Alan J. Husband; Ian A. Ramshaw; Shisan Bao; Klaus I. Matthaei; Georges Koehler; Manfred Kopf

Loudness-Coding Mechanisms Inferred from Electric Stimulation of The Human Auditory System, pp. 564-566

Fan-Gang Zeng; Robert V. Shannon

[URE3] as an Altered URE2 Protein: Evidence for a Prion Analog in Saccharomyces cerevisiae, pp. 566-569

Reed B. Wickner

Requirement of Vascular Integrin α_vβ₃ for Angiogenesis, pp. 569-571

Peter C. Brooks; Richard A. F. Clark; David A. Cheresh

Bacillus subtilis SpoIIIE Protein Required for DNA Segregation During Asymmetric Cell Division, pp. 572-575

Ling Juan Wu; Jeffery Errington

A Neurochemically Distinct Third Channel in the Macaque Dorsal Lateral Geniculate Nucleus, pp. 575-577

Stewart H. C. Hendry; Takashi Yoshioka

Gating Current Noise Produced by Elementary Transitions in Shaker Potassium Channels, pp. 578-582

Daniel Sigg; Enrico Stefani; Francisco Bezanilla

Enhanced Myocardial Function in Transgenic Mice Overexpressing the β₂-Adrenergic Receptor, pp. 582-586

C. A. Milano; L. F. Allen; H. A. Rockman; P. C. Dolber; T. R. McMinn; K. R. Chien; T. D. Johnson; R. A. Bond; R. J. Lefkowitz

Technical Comments

Muscle Biochemistry and a Genetic Study of Myotonic Distrophy, pp. 587-588

Allen D. Roses; Y.-H. Fu; J. A. Pearlman; A. Pizzuti; R. G. Fenwick Jr.; D. L. Friedman; M. B. Perryman; S. Richards; R. A. Gibbs; T. Ashizawa; G. Scarlato; C. T. Caskey

A Truncated Erythropoietin Receptor and Cell Death: A Reanalysis, pp. 588-589

Yukio Nakamura; Hiromitsu Nakauchi

Book Reviews

Life in West Gondwana, p. 601

Biological Relationships Between Africa and South America.

Peter Goldblatt

Review author[s]: S. David Webb

Visual Systems Analysis, p. 602

Contrast Sensitivity

Robert Shapley; Dominic Man-Kit Lam

Review author[s]: Lewis O. Harvey, Jr.

A Trans-Specific Agenda, pp. 602-603

The Great Ape Project. Equality Beyond Humanity.

Paola Cavalieri; Peter Singer

Review author[s]: Russell H. Tuttle

Mechanisms of Control, pp. 603-604

Translational Regulation of Gene Expression 2.

Joseph Ilan

Review author[s]: Dixie J. Goss

Books Received, pp. 604-606

Back Matter (22 pp.)

Previous Issue: New Series, Vol. 264, No. 5157, Apr. 15, 1994
Next Issue: New Series, Vol. 264, No. 5159, Apr. 29, 1994

Science, New Series, Vol. 264, No. 5159, Apr. 29, 1994

Previous Issue: New Series, Vol. 264, No. 5158, Apr. 22, 1994
Next Issue: New Series, Vol. 264, No. 5160, May 6, 1994

Front Matter (16 pp.)
Editorial: The Case for Diversity, p. 639

Daniel E. Koshland Jr.

Letters

K-T Boundary Issues, pp. 641-642

Gerta Keller; Norman MacLeod; Richard A. Kerr

Psychopharmacologic Drugs: Mechanisms of Action, pp. 642-644

Paul Bach-y-Rita; Samuel H. Barondes

Corrections and Clarifications: High Performance Photorefractive Polymers, p. 644
Corrections and Clarifications: Molecular Genetics of Neurological Diseases, p. 644
Corrections and Clarifications: The Brain Behind That Happy Faces, p. 644
ScienceScope, p. 647

Richard Stone

News and Comment

Fusion Research at the Crossroads, pp. 648+650-651

Christopher Anderson

Europeans Launch Effort to Extend JET, p. 649

Michael Cross

Fire Threatens Galápagos Tortoises, p. 651

Rachel Nowak

French Scientists Thwart Plan for Research Reforms, pp. 652-653

Michael Balter

Violence Study Hits a Nerve in Germany, p. 653

Michael Simm

Video Conferencing Lets Physicists Go Head To Head, p. 654

Robert P. Crease

Yellowstone Managers Eye Profits From Hot Microbes, p. 655

Michael Milstein

Random Samples, pp. 656-657

Constance Holden

Research News

Taking a Gamble on the Top Quark, pp. 658-659

Faye Flam

Volcanoes With Bad Hearts Are Tumbling Down All Over, p. 660

Richard A. Kerr

Sea Turtles Master Migration With Magnetic Memories, pp. 661-662

Lisa Seachrist

Throttling Back the Great Lava Floods?, pp. 662-663

Richard A. Kerr

X-rays Make a Smooth Move, p. 663

Tim Appenzeller

Perspectives

Unraveling Function in the TNF Ligand and Receptor Families, pp. 667-668

Bruce Beutler; Christophe van Huffel

Cell Death Genes: Drosophila Enters the Field, pp. 668-669

Martin C. Raff

The Entropic Cost of Bound Water in Crystals and Biomolecules, p. 670

Jack D. Dunitz

Application and Accuracy of Molecular Phylogenies, pp. 671-677

David M. Hillis; John P. Huelsenbeck; Clifford W. Cunningham

Research Article

Genetic Control of Programmed Cell Death in Drosophila, pp. 677-683

Kristin White; Megan E. Grether; John M. Abrams; Lynn Young; Kim Farrell; Hermann Steller

Reports

A Catastrophic Death Assemblage and Paleoclimatic Implications of Pliocene Seabirds of Florida, pp. 684-685

Steven D. Emslie; Gary S. Morgan

A Seismotectonic Model for the 300-Kilometer-Long Eastern Tennessee Seismic Zone, pp. 686-688

Christine A. Powell; G. A. Bollinger; Martin C. Chapman; Matthew S. Sibol; Arch C. Johnston; Russell L. Wheeler

Detection of Large Prehistoric Earthquakes in the Pacific Northwest by Microfossil Analysis, pp. 688-691

Rolf W. Mathewes; John J. Clague

The Last Deglaciation Event in the Eastern Central Arctic Ocean, pp. 692-696

Ruediger Stein; Seung-II Nam; Carsten Schubert; Christoph Vogt; Dieter Futterer; Jan Heinemeier

Engineering Cell Shape and Function, pp. 696-698

Rahul Singhvi; Amit Kumar; Gabriel P. Lopez; Gregory N. Stephanopoulos; Daniel I. C. Wang; George M. Whitesides; Donald E. Ingber

A Genetic Linkage Map for the Zebrafish, pp. 699-703

John H. Postlethwait; Stephen L. Johnson; Clare N. Midson; William S. Talbot; Michael Gates; Eric W. Ballinger; Dana Africa; Rebecca Andrews; Tim Carl; Judith S. Eisen; Sally Horne; Charles B. Kimmel; Mark Hutchinson; Michele Johnson; Andre Rodriguez

Abnormal Development of Peripheral Lymphoid Organs in Mice Deficient in Lymphotoxin, pp. 703-707

Pietro De Togni; Joseph Goellner; Nancy H. Ruddle; Philip R. Streeter; Andrea Fick; Sanjeev Mariathasan; Stacy C. Smith; Rebecca Carlson; Laurie P. Shornick; Jena Strauss-Schoenberger; John H. Russell; Robert Karr; David D. Chaplin

A Lymphotoxin-β-Specific Receptor, pp. 707-710

Paul D. Crowe; Todd L. VanArsdale; Barbara N. Walter; Carl F. Ware; Catherine Hession; Barbara Ehrenfels; Jeffrey L. Browning; Wenie S. Din; Raymond G. Goodwin; Craig A. Smith

Effects of Manipulated Diet on Size and Performance of Brachyuran Crab Claws, pp. 710-712

L. David Smith; A. Richard Palmer

Involvement of Granulocyte-Macrophage Colony-Stimulating Factor in Pulmonary Homeostasis, pp. 713-716

Glenn Dranoff; Alexander D. Crawford; Michel Sadelain; Beverly Ream; Asif Rashid; Roderick T. Bronson; G. Richard Dickersin; Cindy J. Bachurski; Eugene L. Mark; Jeffrey A. Whitsett; Richard C. Mulligan

Identification of a Peptide Recognized by Five Melanoma-Specific Human Cytotoxic T Cell Lines, pp. 716-719

Andrea L. Cox; Jonathan Skipper; Ye Chen; Robert A. Henderson; Timothy L. Darrow; Jeffrey Shabanowitz; Victor H. Engelhard; Donald F. Hunt; Craig L. Slingluff Jr.

Mutagenesis and Mapping of a Mouse Gene, Clock, Essential for Circadian Behavior, pp. 719-725

Martha Hotz Vitaterna; David P. King; Anne-Marie Chang; Jon M. Kornhauser; Phillip L. Lowrey; J. David McDonald; William F. Dove; Lawrence H. Pinto; Fred W. Turek; Joseph S. Takahashi

Book Reviews

Ecological Comprehensiveness, pp. 726-727

A History of the Ecosystem Concept in Ecology. More Than the Sum of the Parts.

Frank Benjamin Golley

Review author[s]: Clyde E. Goulden

Intergradations, pp. 727-728

Hybrid Zones and the Evolutionary Process.

Richard G. Harrison

Review author[s]: Jack W. Sites, Jr.

Diamond-Making, pp. 728-729

The New Alchemists. Breaking Through the Barriers of High Pressure.

Robert M. Hazen

Review author[s]: A. Jayaraman

Books Received, p. 729

Inside AAAS, p. 730

Diana Pabst

Back Matter (14 pp.)

Previous Issue: New Series, Vol. 264, No. 5158, Apr. 22, 1994
Next Issue: New Series, Vol. 264, No. 5160, May 6, 1994

Science, New Series, Vol. 264, No. 5160, May 6, 1994

Previous Issue: New Series, Vol. 264, No. 5159, Apr. 29, 1994
Next Issue: New Series, Vol. 264, No. 5161, May 13, 1994

Front Matter (24 pp.)
Editorial: Reorientation of Research Objectives, p. 755

Philip H. Abelson

Letters

Inappropriate Analogy, p. 757

Diana Lane; John Benditt

Black Rhino Conservation, p. 757

Joel Berger; Carol Cunningham

Outcomes Research, pp. 757-759

Anne T. Berg; Barbara G. Vickrey; John E. Wennberg; Michael J. Barry

Population Policy Options, p. 760

Michel Treisman

Corrections and Clarifications: Beyond the Wall: Memoirs of an East and West German Spy, p. 760
ScienceScope, p. 763

Richard Stone

News and Comment

Anxiety Hits Mental Health Institute, pp. 764-765

Eliot Marshall

New Program Funds Genome Technology, p. 766

Christopher Anderson

Was Safer Cigarette Research Snuffed?, pp. 766-767

Rachel Nowak

Scientists Return to the Elementary-School Classroom, pp. 768-769

Joseph Alper

Random Samples, pp. 770-771

Constance Holden

Research News

Neurotrophic Factors Enter the Clinic, pp. 772-774

Marcia Barinaga

Neurons Tap Out a Code That May Help Locate Sounds, p. 775

Marcia Barinaga

Small Army of Code-Breakers Conquers a 129-Digit Giant, pp. 776-777

Gary Taubes

Physicists Find a Double Dose of Magic, p. 777

Michael Simm; Daniel Clery

Microbial Mining Boosts the Environment, Bottom Line, pp. 778-779

Anne Simon Moffat

Policy Forum

Between Prison and Probation: Intermediate Sanctions, pp. 791-793

Patrick A. Langan

Perspectives

Advanced Inorganic Materials: An Open Horizon, pp. 794-795

Anthony K. Cheetham

Selecting the T Cell Receptor Repertoire, pp. 796-797

Michael J. Bevan; Kristin A. Hogquist; Stephen C. Jameson

Global Variations in the Geoid/Topography Admittance of Venus, pp. 798-803

Mark Simons; Bradford H. Hager; Sean C. Solomon

Earthquakes with Non-Double-Couple Mechanisms, pp. 804-809

Cliff Frohlich

Research Article

Dielectric Asymmetry in the Photosynthetic Reaction Center, pp. 810-816

Martin A. Steffen; Kaiqin Lao; Steven G. Boxer

Reports

Nature's Carbonylation Catalyst: Raman Spectroscopic Evidence That Carbon Monoxide Binds to Iron, Not Nickel, in CO Dehydrogenase, pp. 817-819

Di Qiu; Manoj Kumar; Stephen W. Ragsdale; Thomas G. Spiro

Direct Observation of Tube-Like Motion of a Single Polymer Chain, pp. 819-822

Thomas T. Perkins; Douglas E. Smith; Steven Chu

Relaxation of a Single DNA Molecule Observed by Optical Microscopy, pp. 822-826

Thomas T. Perkins; Stephen R. Quake; Douglas E. Smith; Steven Chu

Surface Vibrational Spectroscopic Studies of Hydrogen Bonding and Hydrophobicity, pp. 826-828

Quan Du; Eric Freysz; Y. Ron Shen

A Crested Theropod Dinosaur from Antarctica, pp. 828-830

William R. Hammer; William J. Hickerson

Diurnal and Semidiurnal Variations in the Earth's Rotation Rate Induced by Oceanic Tides, pp. 830-832

R. D. Ray; D. J. Steinberg; B. F. Chao; D. E. Cartwright

Cure of Xenografted Human Tumors by Bispecific Monoclonal Antibodies and Human T Cells, pp. 833-835

Christoph Renner; Wolfram Jung; Ugur Sahin; Ralf Denfeld; Christoph Pohl; Lorenz Trümper; Frank Hartmann; Volker Diehl; René van Lier; Michael Pfreundschuh

Control of Cell Behavior During Vertebrate Development by Slug, a Zinc Finger Gene, pp. 835-839

M. Angela Nieto; Michael G. Sargent; David G. Wilkinson; Jonathan Cooke

Microtubule Dynamics Modulated by Guanosine Triphosphate Hydrolysis Activity of β-Tubulin, pp. 839-842

Ashley Davis; Carleton R. Sage; Cynthia A. Dougherty; Kevin W. Farrell

A Panoramic Code for Sound Location by Cortical Neurons, pp. 842-844

John C. Middlebrooks; Ann E. Clock; Li Xu; David M. Green

Specification of Pore Properties by the Carboxyl Terminus of Inwardly Rectifying K⁺ Channels, pp. 844-847

Maurizio Taglialatela; Barbara A. Wible; Roberta Caporaso; Arthur M. Brown

Neural Tuning for Sound Duration: Role of Inhibitory Mechanisms in the Inferior Colliculus, pp. 847-850

J. H. Casseday; D. Ehrlich E. Covey

Differential Effects of Apolipoproteins E3 and E4 on Neuronal Growth in Vitro, pp. 850-852

B. P. Nathan; S. Bellosta; D. A. Sanan; K. H. Weisgraber; R. W. Mahley; R. E. Pitas

Book Reviews

Pulsar Processes, p. 853

Physics of the Pulsar Magnetosphere.

V. S. Beskin; A. V. Gurevich; Ya. N. Istomin

Review author[s]: Donald B. Melrose

Genome Informatics, p. 854

Biocomputing. Informatics and Genome Projects.

Douglas W. Smith

Review author[s]: Chris Fields

Aerial Technology, pp. 855-856

Power from Wind. A History of Windmill Technology.

Richard L. Hills

Review author[s]: Terry S. Reynolds

Books Received, pp. 856-857

Back Matter (19 pp.)

Previous Issue: New Series, Vol. 264, No. 5159, Apr. 29, 1994
Next Issue: New Series, Vol. 264, No. 5161, May 13, 1994

Science, New Series, Vol. 264, No. 5161, May 13, 1994

Previous Issue: New Series, Vol. 264, No. 5160, May 6, 1994
Next Issue: New Series, Vol. 264, No. 5162, May 20, 1994

Front Matter (21 pp.)
Editorial: Research in the Service of Jobs and Health, p. 887

Daniel E. Koshland, Jr.

Letters

Milk Safety, pp. 889-890

Andrew L. Rubin; Mark Goodman

NAGPRA's Implications, p. 890

James W. Bradley; John Bryant

Indirect Pesticide Costs, p. 890

David Pimentel

Corrections and Clarifications: Livermore Faces Forces of Change, p. 891
Corrections and Clarifications: An Atomic Film Festival, p. 891
Corrections and Clarifications: Nicotine Scrutinized as FDA Seeks to Regulate Cigarettes, p. 891
Corrections and Clarifications: Sea-Surface Temperature from Coral Skeletal Strontium/Calcium Ratios, p. 891
Corrections and Clarifications: Requirement for the Yeast Gene LON in Intramitochondrial Proteolysis and Maintenance of Respiration, p. 891
ScienceScope, p. 895

Richard Stone

News and Comment

Strong Medicine for NIH, pp. 896-898

Eliot Marshall

DOE Ponders Yet More Uses for SSC, p. 898

Christopher Anderson

Toxic Tiff Spreads Beyond France, pp. 898-899

Michael Balter

House Trims NSF Funding Plan, p. 899

Jeffrey Mervis

Cyberspace Offers Chance To Do 'Virtually' Real Science, pp. 900-901

Christopher Anderson

Random Samples, pp. 902-903

Constance Holden

Research News

Zebrafish Hit the Big Time, pp. 904-905

Patricia Kahn

Dying Stars Give Galactic Theory New Life, p. 906

John Travis

Red Galaxies Hint at an Old Universe, pp. 906-907

Ray Jayawardhana

Keeping Tabs on Cometary Breakups, p. 907

Ray Jayawardhana

A New Twist in the Tale of Nature's Asymmetry, p. 908

David Bradley

Post-Polio Syndrome: Remembrance of Viruses Past, p. 909

Richard Stone

Perspectives

Distant Effects of Volcanism-How Big and How Often?, pp. 913-914

Tom Simkin

Folding Pattern Diversity of Integral Membrane Proteins, pp. 914-916

S. W. Cowan; Jürg P. Rosenbusch

Terawatt to Petawatt Subpicosecond Lasers, pp. 917-924

Michael D. Perry; Gerard Mourou

Sex Determination and Dosage Compensation: Lessons from Flies and Worms, pp. 924-932

Susan M. Parkhurst; Philip M. Meneely

Research Article

Drosophila TAF _ll 150: Similarity to Yeast Gene TSM-1 and Specific Binding to Core Promoter DNA, pp. 933-941

C. Peter Verrijzer; Kyoko Yokomori; Jin-Long Chen; Robert Tjian

Reports

Observation of Quantum-Size Effects at Room Temperature on Metal Surfaces With STM, pp. 942-945

Phaedon Avouris; In-Whan Lyo

Diacetylenic Lipid Tubules: Experimental Evidence for a Chiral Molecular Architecture, pp. 945-947

J. M. Schnur; B. R. Ratna; J. V. Selinger; A. Singh; G. Jyothi; K. R. K. Easwaran

Record of Volcanism Since 7000 B.C. from the GISP2 Greenland Ice Core and Implications for the Volcano-Climate System, pp. 948-952

G. A. Zielinski; P. A. Mayewski; L. D. Meeker; S. Whitlow; M. S. Twickler; M. Morrison; D. A. Meese; A. J. Gow; R. B. Alley

Seven Million Years of Glaciation in Greenland, pp. 952-955

H. C. Larsen; A. D. Saunders; P. D. Clift; J. Beget; W. Wei; S. Spezzaferri

Isotopic Evidence for Neogene Hominid Paleoenvironments in the Kenya Rift Valley, pp. 955-959

John D. Kingston; Bruno D. Marino; Andrew Hill

Retention and 5′ Cap Trimethylation of U3 snRNA in the Nucleus, pp. 959-961

Michael P. Terns; James E. Dahlberg

Role of Bone Marrow-Derived Cells in Presenting MHC Class I-Restricted Tumor Antigens, pp. 961-965

Alex Y. C. Huang; Paul Golumbek; Mojgan Ahmadzadeh; Elizabeth Jaffee; Drew Pardoll; Hyam Levitsky

Cloning of a T Cell Growth Factor That Interacts with the β Chain of the Interleukin-2 Receptor, pp. 965-968

Kenneth H. Grabstein; June Eisenman; Kurt Shanebeck; Charles Rauch; Subhashini Srinivasan; Victor Fung; Courtney Beers; Jane Richardson; Michael A. Schoenborn; Minoo Ahdieh; Lisabeth Johnson; Mark R. Alderson; James D. Watson; Dirk M. Anderson; Judith G. Giri

Enhancer Point Mutation Results in a Homeotic Transformation in Drosophila, pp. 968-971

Mary Jane Shimell; Jeffrey Simon; Welcome Bender; Michael B. O'Connor

Cloning of a Grb2 Isoform with Apoptotic Properties, pp. 971-974

Isabelle Fath; Fabien Schweighoffer; Isabelle Rey; Marie-Christine Multon; Janine Boiziau; Marc Duchesne; Bruno Tocque

Activity-Dependent Changes in the Intrinsic Properties of Cultured Neurons, pp. 974-977

Gina Turrigiano; L. F. Abbott; Eve Marder

Aberrant Neurites and Synaptic Vesicle Protein Deficiency in Synapsin II-Depleted Neurons, pp. 977-979

Adriana Ferreira; Kenneth S. Kosik; Paul Greengard; Hui-Quan Han

Book Reviews

Grand Narratives Scrutinized, pp. 980-982

The Literature of Science. Perspectives on Popular Scientific Writing.

Murdo William McRae

Review author[s]: Joseph W. Slade

Underlaborers for Science, pp. 982-983

Taking the Naturalistic Turn. Or, How Real Philosophy of Science is Done.

Werner Callebaut

Review author[s]: Steve Fuller

Pipers and Tunes in Science, pp. 983-984

Prometheus Bound. Science in a Dynamic Steady State.

John Ziman

Review author[s]: Rodney W. Nichols

Taking Arms, pp. 985-986+989

Higher Superstition. The Academic Left and Its Quarrels with Science.

Paul R. Gross; Norman Levitt

Review author[s]: Bennett M. Berger

An Actor in Recent History, pp. 989-990

James B. Conant. Harvard to Hiroshima and the Making of the Nuclear Age.

James B. Conant; James G. Hershberg

Review author[s]: Carol S. Gruber

Decryption Day by Day, pp. 990-992

Codebreakers. The Inside Story at Bletchley Park.

F. H. Hinsley; Alan Stripp

Review author[s]: Paul Ceruzzi

Cold War Social Science, pp. 992-993

Science of Coercion. Communication Research and Psychological Warfare, 1945-1960.

Christopher Simpson

Review author[s]: Leila Zenderland

The Industrialization of Chemistry, pp. 993-994

The Rainbow Makers. The Origins of the Synthetic Dyestuffs Industry in Western Europe.

Anthony S. Travis

Review author[s]: John W. Servos

Unlikely Contrivances, pp. 994-996

Zipper. An Exploration in Novelty.

Robert Friedel

Review author[s]: Ken Alder

Airwave Accommodations, pp. 996-997

Selling Radio. The Commercialization of American Broadcasting, 1920-1934.

Susan Smulyan

Review author[s]: Clayton R. Koppes

The Chemical Past, pp. 997-999

The Norton History of Chemistry.

William H. Brock

Ideas in Chemistry. A History of the Science.

David Knight

The History of Chemistry.

John Hudson

Histoire de la Chimie.

Bernadette Bensaude-Vincent; Isabelle Stengers

Review author[s]: Mary Jo Nye

Adventures in Space-Time, pp. 999-1001

Black Holes and Time Warps. Einstein's Outrageous Legacy.

Kip S. Thorne

Review author[s]: Joseph Silk

Gravimetrists in Action, pp. 1001-1002

The Rise and Fall of the Fifth Force. Discovery, Pursuit, and Justification in Modern Physics.

Allan Franklin

Review author[s]: George T. Gillies

Southernmost Fauna, pp. 1002-1004

Antarctic Fish Biology. Evolution in a Unique Environment.

Joseph T. Eastman; Danette Pratt; William Winn

Antarctic Fish and Fisheries.

Karl-Hermann Kock

History and Atlas of the Fishes of the Antarctic Ocean.

Richard Gordon Miller; Philip A. Hastings; Josette Gourley

Review author[s]: David Policansky

Eocene Revelations, pp. 1004-1005

Messel. An Insight Into the History of Life and of the Earth.

Stephan Schaal; Willi Ziegler

Review author[s]: Jason A. Lillegraven

Big Cats in Situ, pp. 1005-1006

The African Leopard. Ecology and Behavior of a Solitary Felid.

Theodore N. Bailey

Review author[s]: John Seidensticker

Saccharomyces and Company, pp. 1006+1008

The Early Days of Yeast Genetics.

Michael N. Hall; Patrick Linder

Review author[s]: Jasper Rine

Evolution in the Fast Lane, pp. 1008+1010

The Evolutionary Biology of Viruses.

Stephen S. Morse

Review author[s]: David M. Hillis

Getting into Shape, pp. 1010-1011

Kinetic Theory of Living Pattern.

Lionel G. Harrison

Review author[s]: Edward Cox

Visual Functions, pp. 1011-1012

A Vision of the Brain.

Semir Zeki

Review author[s]: Peter Lennie

Cognition Unawares, p. 1013

Implicit Learning and Tacit Knowledge. An Essay on the Cognitive Unconscious.

Arthur S. Reber

Review author[s]: John F. Kihlstrom

Growing Up in Context, pp. 1013-1015

Children in Time and Place. Developmental and Historical Insights.

Glen H. Elder, Jr.; John Modell; Ross D. Parke

Review author[s]: Kathleen W. Jones

Help and Containment, pp. 1015-1016

Inventing the Feeble Mind. A History of Mental Retardation in the United States.

James W. Trent, Jr.

Review author[s]: Ellen Dwyer

A Health Care Campaign, pp. 1016-1018

Bargaining for Life. A Social History of Tuberculosis, 1876-1938.

Barbara Bates

Review author[s]: Naomi Rogers

The Generation of Culture, pp. 1018-1019

Balinese Worlds.

Fredrik Barth

Review author[s]: John R. Bowen

Early Literacy, pp. 1019-1020

Archaic Bookkeeping. Early Writing and Techniques of Economic Administration in the Ancient Near East.

Hans J. Nissen; Peter Damerow; Robert K. Englund

Review author[s]: Piotr Michalowski

Arctic Gold, pp. 1021-1023

Archeology of the Frobisher Voyages.

William W. Fitzhugh; Jacqueline S. Olin

The Meta Incognita Project. Contributions to Field Studies.

Stephen Alsford

Review author[s]: Edwin S. Hall

Ventures Southward, pp. 1023-1024

Before the Heroes Came. Antarctica in the 1890s.

T. H. Baughman

Review author[s]: G. E. Fogg

American Bogpersons, pp. 1024-1025

Archaeology of Precolumbian Florida.

Jerald T. Milanich

Review author[s]: Paul D. Welch

Books Reviewed in Science 21 May 1993 Through 6 May 1994, pp. 1025-1028

Books Received, p. 1028

Back Matter (24 pp.)

Previous Issue: New Series, Vol. 264, No. 5160, May 6, 1994
Next Issue: New Series, Vol. 264, No. 5162, May 20, 1994