Science, New Series, Vol. 259, No. 5091, Jan. 1, 1993

Previous Issue: New Series, Vol. 258, No. 5090, Dec. 18, 1992
Next Issue: New Series, Vol. 259, No. 5092, Jan. 8, 1993

Front Matter (22 pp.)
Editorial: Self-Esteem Through Fantasy, p. 11

Daniel E. Koshland, Jr.

Letters

Peer Review of "Performance Review"?, pp. 13-14

Rustum Roy; Russell Messier; Daniel E. Koshland, Jr

AIDS Theories, p. 14

Tom Curtis

Support for Pluto Mission, pp. 14-15

Alan Stern; Eliot Marshall

Policy Forum

Health Care Cost Containment: Some Implications of Global Budgets, pp. 16-17+105

Carl M. Stevens

ScienceScope, p. 19

Richard Stone

News and Comment

Bromley's Last Stand, pp. 20-21

Christopher Anderson

`Strategic Research' Wins the Day, p. 21

Christopher Anderson

An Awesom Look at Japan's Math SAT, p. 22

Barry Cipra

Healy and Collins Strike a Deal, pp. 22-23

Larry Thompson

How U.S. Companies Measure Up, p. 23

John Travis

Will Fermilab Find Its Future by Looking to the Stars?, p. 24

Faye Flam

Research News

Inflamed Debate Over Neurotoxin, pp. 25-26

David Holzman

If You Can't See It, Don't Believe It..., pp. 26-27

Barry Cipras

Catastrophes of Every Ilk at The Geophysics Fest, pp. 28-29

Richard A. Kerr

Is Devastating Whitefly Invader Really a New Species?, p. 30

Marcia Barinaga

Galaxies Keep Going with the Flow, p. 31

Faye Flam

Microwave Ripples Have a Reprise, p. 31

Faye Flam

Random Samples, pp. 32-33

Constance Holden

Perspectives

Gigamolecules in Flatland, pp. 43-44

Edwin L. Thomas

Organic Synthesis of Prostaglandins: Advancing Biology, pp. 44-45

Ryoji Noyori; Masaaki Suzuki

The Colonization of Beringia and the Peopling of the New World, pp. 46-53

John F. Hoffecker; W. Roger Powers; Ted Goebel

Mathematics Achievement of Chinese, Japanese, and American Children: Ten Years Later, pp. 53-58

Harold W. Stevenson; Chuansheng Chen; Shin-Ying Lee

Research Article

Synthesis of Two-Dimensional Polymers, pp. 59-63

S. I. Stupp; S. Son; H. C. Lin; L. S. Li

Reports

Selective Perhydroxylation of Squalene: Taming the Arithmetic Demon, pp. 64-66

Gerard A. Crispino; Pui Tong Ho; K. Barry Sharpless

Effect of Pressure on the Composition of the Lower Mantle End Member Fe_xO, pp. 66-68

Catherine McCammon

A Traveling-Wave Amplifier Model of the Cochlea, pp. 68-71

Allyn Hubbard

Vapor Pressures of Solid Hydrates of Nitric Acid: Implications for Polar Stratospheric Clouds, pp. 71-74

Douglas R. Worsnop; Lewis E. Fox; Mark S. Zahniser; Steven C. Wofsy

Identification of a Whitefly Species by Genomic and Behavioral Studies, pp. 74-77

Thomas M. Perring; Arthur D. Cooper; Russell J. Rodriquez; Charles A. Farrar; Tom S. Bellows, Jr.

Mediation by G Proteins of Signals that Cause Collapse of Growth Cones, pp. 77-79

Michihiro Igarashi; Stephen M. Strittmatter; Timothy Vartanian; Mark C. Fishman

Role of Intracellular Calcium in NI-35-Evoked Collapse of Neuronal Growth Cones, pp. 80-83

Christine E. Bandtlow; Marc F. Schmidt; Tim D. Hassinger; Martin E. Schwab; S. B. Kater

Regulation of the Human hsp70 Promoter by p53, pp. 84-87

S. Nicholas Agoff; Jeannie Hou; Daniel I. H. Linzer; Barbara Wu

Adipose Expression of Tumor Necrosis Factor-α: Direct Role in Obesity-Linked Insulin Resistance, pp. 87-91

Gökhan S. Hotamisligil; Narinder S. Shargill; Bruce M. Spiegelman

Requirements of CD8⁺ Cells in T Cell Receptor Peptide-Induced Clonal Unresponsiveness, pp. 91-94

Amitabh Gaur; Richard Haspel; John P. Mayer; C. Garrison Fathman

Treatment and Prevention of Rat Glioblastma by Immunogenic C6 Cells Expressing Antisense Insulin-Like Growth Factor I RNA, pp. 94-97

Jerzy Trojan; Thomas R. Johnson; Susan D. Rudin; Judith Ilan; Mark L. Tykocinski; Joseph Ilan

Dormancy of Inhibitory Interneurons in a Model of Temporal Lobe Epilepsy, pp. 97-100

Jonathan W. Bekenstein; Eric W. Lothman

Selectivity for Polar, Hyperbolic, and Cartesian Gratings in Macaque Visual Cortex, pp. 100-103

Jack L. Gallant; Jochen Braun; David C. Van Essen

Technical Comment

Tritium and Radiocarbon Dating of Canada Basin Deep Waters, pp. 103-104

R. W. Macdonald; E. C. Carmack

Book Reviews

Correlates of Creativity, pp. 107-108

Striking the Mother Lode in Science. The Importance of Age, Place, and Time.

Paula E. Stephan; Sharon G. Levin

Review author[s]: Stuart Blume

Human Curiosiy, pp. 108-109

Ota. The Pygmy in the Zoo.

Phillips Verner Bradford; Harvey Blume

Review author[s]: Robert W. Rydell

Products of Recombination, p. 109

Transgenic Animals.

F. Grosveld; G. Kollias

Review author[s]: Robert J. Wall

Medical Excesses, pp. 109-111

Spare Parts. Organ Replacement in American Society.

Renée C. Fox; Judith P. Swazey

Review author[s]: John A. Robertson

Books Received, pp. 111-112

Back Matter (36 pp.)

Previous Issue: New Series, Vol. 258, No. 5090, Dec. 18, 1992
Next Issue: New Series, Vol. 259, No. 5092, Jan. 8, 1993

Science, New Series, Vol. 259, No. 5092, Jan. 8, 1993

Previous Issue: New Series, Vol. 259, No. 5091, Jan. 1, 1993
Next Issue: New Series, Vol. 259, No. 5093, Jan. 15, 1993

Front Matter (20 pp.)
Editorial: Regulatory Costs, p. 159

Philip H. Abelson

Letters

Gun Ownership and Risk, p. 161

Paul H. Blackman; Kenneth Kulman; Arthur Kellermann

The Future of Agricultural Research, pp. 162-163

Roger Beachy; Susanne L. Huttner; Anne K. Vidaver; Paul Lyrene; Kenneth A. Dahlberg

Antibiotic Resistance, pp. 163-164

Vickers Burdett

Enigmatic Arctic Cloud Plumes, p. 164

Charles K. Paull; William J. Buelow

ScienceScope, p. 167

Richard Stone

News and Comment

HHS: Gallo Guilty of Misconduct, pp. 168-170

Jon Cohen

Clinton Picks His Science Adviser, p. 171

Christopher Anderson

A Cloud With a Strange Dark Lining, pp. 171-172

Faye Flam

Healy Approves an Unproven Treatment, p. 172

Larry Thompson

Research News

How Do Particles Put on Weight?, pp. 173-174

Paul Selvin

Ancient and Modern, Rock and Fluid Meet in San Francisco, pp. 175-176

Richard A. Kerr

Magnetic Ripple Hints Gaspra Is Metallic, p. 176

Richard A. Kerr

Astronomers Turn New Eyes On the Cosmic Ray Sky, pp. 177-179

Gary Taubes

Random Samples, pp. 180-181

Constance Holden

The Directed Mutation Controversy and Neo-Darwinism, pp. 188-194

Richard E. Lenski; John E. Mittler

Atmospheric Lifetimes of Long-Lived Halogenated Species, pp. 194-199

A. R. Ravishankara; S. Solomon; A. A. Turnipseed; R. F. Warren

Research Article

A 100-Year Average Recurrence Interval for the San Andreas Fault at Wrightwood, California, pp. 199-203

Thomas E. Fumal; Silvio K. Pezzopane; Ray J. Weldon II; David P. Schwartz

Reports

Verification of the Onsager Reciprocal Relations in a Molten Silicate Solution, pp. 204-206

Frank J. Spera; Alain F. Trial

Comparative Compressibilities of Silicate Spinels: Anomalous Behavior of (Mg,Fe)₂SiO₄, pp. 206-209

Robert M. Hazen

Mechanism Diversity of the Loma Prieta Aftershocks and the Mechanics of Mainshock-Aftershock Interaction, pp. 210-213

Gregory C. Beroza; Mark D. Zoback

Domain Structures in Langmuir-Blodgett Films Investigated by Atomic Force Microscopy, pp. 213-216

L. F. Chi; M. Anders; H. Fuchs; R. R. Johnston; H. Ringsdorf

An Inhibitor of p34 ^CDC28 Protein Kinase Activity from Saccharomyces cerevisiae, pp. 216-219

Michael D. Mendenhall

The Prevention of Thymic Lymphomas in Transgenic Mice by Human O⁶-Alkylguanine-DNA Alkyltransferase, pp. 219-222

Luba L. Dumenco; Esther Allay; Kathleen Norton; Stanton L. Gerson

Terrestrial Soft-Bodied Protists and Other Microorganisms in Triassic Amber, pp. 222-224

George O. Poinar, Jr.; Benjamin M. Waggoner; Ulf-Christian Bauer

Presentation of a Viral T Cell Epitope Expressed in the CDR3 Region of a Self Immunoglobulin Molecule, pp. 224-227

Habib Zaghouani; Ralph Steinman; Ruta Nonacs; Himanshu Shah; Walter Gerhard; Constantin Bona

Evidence for a Clonal Origin of Methicillin Resistance in Staphylococcus aureus, pp. 227-230

Barry Kreiswirth; John Kornblum; Robert D. Arbeit; William Eisner; Joel N. Maslow; Allison McGeer; Donald E. Low; Richard P. Novick

Regulation of Heat Shock Factor Trimer Formation: Role of a Conserved Leucine Zipper, pp. 230-234

Sridhar K. Rabindran; Raymond I. Haroun; Joachim Clos; Jan Wisniewski; Carl Wu

Rate and Mechanism of Nonhomologous Recombination During a Single Cycle of Retroviral Replication, pp. 234-238

Jiayou Zhang; Howard M. Temin

Circadian Rhythm in Membrane Conductance Expressed in Isolated Neurons, pp. 239-241

Stephan Michel; Michael E. Geusz; Joshua J. Zaritsky; Gene D. Block

Tyrosine Phosphorylation of Actin in Dictyostelium Associated with Cell-Shape Changes, pp. 241-244

Peter K. Howard; Bartholomew M. Sefton; Richard A. Firtel

Forward Plasma Membrane Flow in Growing Nerve Processes, pp. 244-246

Sergey Popov; Abraham Brown; Mu-Ming Poo

Book Reviews

Asking and Answering, pp. 248-249

Questions about Questions. Inquiries into the Cognitive Basis of Surveys.

Judith M. Tanur

Review author[s]: William Sims Bainbridge

Opinions on Geology, pp. 249-250

Challenger at Sea. A Ship That Revolutionized Earth Science.

Kenneth J. Hsu

Review author[s]: William P. Dillon

Earth's Early Life, pp. 250-252

The Proterozoic Biosphere. A Multidisciplinary Study.

J. William Schopf; Cornelis Klein

Review author[s]: Andrew H. Knoll

Books Received, p. 252

Back Matter (28 pp.)

Previous Issue: New Series, Vol. 259, No. 5091, Jan. 1, 1993
Next Issue: New Series, Vol. 259, No. 5093, Jan. 15, 1993

Science, New Series, Vol. 259, No. 5093, Jan. 15, 1993

Previous Issue: New Series, Vol. 259, No. 5092, Jan. 8, 1993
Next Issue: New Series, Vol. 259, No. 5094, Jan. 22, 1993

Front Matter (24 pp.)
Editorial: Basic Research (I), p. 291

Daniel E. Koshland, Jr.

Letters

NASA Asteroid Report, p. 293

John D. G. Rather

Knuckle-Walking Ancestors, pp. 293-294

Brian T. Shea; Sandra E. Inouye; David R. Begun

Conservation: Should Drug Companies Share in the Costs?, pp. 294-295

Thomas Eisner; Ignacio Chapela

Addendum: Crystal Structure at 3.5 \angst Resolution of HIV-1 Reverse Transcriptase Complexed with an Inhibitor, p. 295

Thomas A. Steitz; Lori A. Kohlstaedt; Jimin Wang; Jonathan M. Friedman; Phoebe A. Rice

Alliteration Accidental?, p. 295

Thomas J. Volk

Policy Forum

Marine Sciences in the Coming Decades, pp. 296-297

Carl Wunsch

ScienceScope, p. 299

Richard Stone

News and Comment

Genome Project Goes Commercial, pp. 300-302

Christopher Anderson

Gene Therapists Jump Ship..., p. 303

Larry Thompson

...Top AIDS Official to Leave, p. 303

Jon Cohen

UC Berkeley Embroiled in Computer Software Lawsuit, pp. 304-305

John Travis

Wake-Up Call for Sleep Research, p. 305

Constance Holden

Research News

New Superconductors: A Slow Dawn, pp. 306-308

Ivan Amato

Carbon Monoxide: Killer to Brain Messenger in One Step, p. 309

Marcia Barinaga

A Stimulating New Approach To Cancer Treatment, pp. 310-311

John Travis

Catalytic Conversion Could be a Gas, p. 311

Ivan Amato

Geneticists Trace the DNA Trail of the First Americans, pp. 312-313

Ann Gibbons

Random Samples, p. 314

Constance Holden

Perspective

Cyclic ADP-Ribose: A New Way to Control Calcium, pp. 325-326

Antony Galione

Far-Ultraviolet Astronomy on the Astro-1 Space Shuttle Mission, pp. 327-334

Arthur F. Davidsen

Research Article

Particles Floating on a Moving Fluid: A Dynamically Comprehensible Physical Fractal, pp. 335-339

John C. Sommerer; Edward Ott

Reports

A Mercury-Catalyzed, High-Yield System for the Oxidation of Methane to Methanol, pp. 340-343

Roy A. Periana; Douglas J. Taube; Eric R. Evitt; Daniel G. Löffler; Paul R. Wentrcek; George Voss; Toshihiko Masuda

Production of Syngas by Direct Catalytic Oxidation of Methane, pp. 343-346

D. A. Hickman; L. D. Schmidt

Single Crystal Metals Encapsulated in Carbon Nanoparticles, pp. 346-348

Rodney S. Ruoff; Donald C. Lorents; Bryan Chan; Ripudaman Malhotra; Shekhar Subramoney

Paleohydrology of Late Pleistocene Superflooding, Altay Mountains, Siberia, pp. 348-350

Victor R. Baker; Gerardo Benito; Alexey N. Rudoy

Why Does the Earth Spin Forward?, pp. 350-354

Luke Dones; Scott Tremaine

Mechanisms in the Competitive Success of an Invading Sexual Gecko over an Asexual Native, pp. 354-358

Kenneth Petren; Douglas T. Bolger; Ted J. Case

Two Open Complexes and a Requirement for Mg ²⁺ to Open the λP_R Transcription Start Site, pp. 358-361

Won-Chul Suh; Wilma Ross; M. Thomas Record, Jr.

Molecular Mapping and Detoxification of the Lipid A Binding Site by Synthetic Peptides, pp. 361-365

Alessandro Rustici; Massimo Velucchi; Raffaella Faggioni; Marina Sironi; Pietro Ghezzi; Sally Quataert; Bruce Green; Massimo Porro

Sequence-Specific Binding of Transfer RNA by Glyceraldehyde-3-Phosphate Dehydrogenase, pp. 365-368

Ravinder Singh; Michael R. Green

Tumor Rejection After Direct Costimulation of CD8⁺ T Cells by B7- Transfected Melanoma Cells, pp. 368-370

Sarah E. Townsend; James P. Allison

Cyclic ADP-Ribose in Insulin Secretion from Pancreatic β Cells, pp. 370-373

Shin Takasawa; Koji Nata; Hideto Yonekura; Hiroshi Okamoto

Blood-Brain Barrier Penetration and in Vivo Activity of an NGF Conjugate, pp. 373-377

Phillip M. Friden; Lee R. Walus; Patricia Watson; Susan R. Doctrow; John W. Kozarich; Cristina Bäckman; Hanna Bergman; Barry Hoffer; Floyd Bloom; Ann-Charlotte Granholm

Retinal Degeneration in Choroideremia: Deficiency of Rab Geranylgeranyl Transferase, pp. 377-381

Miguel C. Seabra; Michael S. Brown; Joseph L. Goldstein

Carbon Monoxide: A Putative Neural Messenger, pp. 381-384

Ajay Verma; David J. Hirsch; Charles E. Glatt; Gabriele V. Ronnett; Solomon H. Snyder

Book Reviews

Aspirations in Santa Fe, pp. 387-388

Complexity: The Emerging Science at the Edge of Order and Chaos.

M. Mitchell Waldrop

Complexity: Life at the Edge of Chaos.

Roger Lewin

Review author[s]: Lionel G. Harrison

Timepieces, pp. 388-389

Ivory Diptych Sundials, 1570-1750.

Steven A. Lloyd

Review author[s]: Bernard R. Goldstein

2-D Physics, p. 390

Two-Dimensional Crystals.

Igor Lyuksyutov; A. G. Naumovets; V. Pokrovsky

Review author[s]: D. P. DiVincenzo

Vertebrate Adaptations, pp. 390-391

Environmental Physiology of the Amphibians.

Martin E. Feder; Warren W. Burggren

Review author[s]: Cynthia Carey

Books Received, p. 391

Back Matter (37 pp.)

Previous Issue: New Series, Vol. 259, No. 5092, Jan. 8, 1993
Next Issue: New Series, Vol. 259, No. 5094, Jan. 22, 1993

Science, New Series, Vol. 259, No. 5094, Jan. 22, 1993

Previous Issue: New Series, Vol. 259, No. 5093, Jan. 15, 1993
Next Issue: New Series, Vol. 259, No. 5095, Jan. 29, 1993

Front Matter (19 pp.)
Editorial: President Clinton's Science Adviser, p. 439

Philip H. Abelson

Letters

Business and Science, p. 441

Thomas D. Brock

Measles Vaccine: Titre and Safety, pp. 441-442

Vlatko Silobrc̄ić; Michel Garenne

Research in Japan, p. 442

William E. Luttrell; George J. Klir

Brain Research in Europe, p. 442

J. Mendlewicz

Fetal Transplant Update, pp. 442-443

E. R. Hitchcock

Endangered Species Act, p. 443

William Robert Irvin

Policy Forum

Science and the New Administration, pp. 444-445

J. Michael Bishop; Marc Kirschner; Harold Varmus

ScienceScope, p. 447

Richard Stone

News and Comment

A Grisly Archive of Key Cancer Data, pp. 448-451

Patricia Kahn

Researchers Eager to See Soviet Data, p. 451

Eliot Marshall

Should Dying Patients Receive Untested Genetic Methods?, p. 452

Larry Thompson

Will the Real Journal Please Stand Up?, p. 453

Christopher Anderson

Research News

A Continent-Sized Ear on the Cosmos, pp. 454-456

Peter Aldhous

Computing at the Speed of Light, p. 456

M. Mitchell Waldrop

Alzheimer's Pathology Begins to Yield Its Secrets, pp. 457-458

Jean Marx

Astronomers Meet in Phoenix, Recount a Stellar Year, pp. 458-459

Faye Flam

Random Samples, pp. 460-461

Constance Holden

Perspectives

Catalytic Antibodies and Disfavored Reactions, pp. 469-470

Samuel Danishefsky

The Polar Coordinate Model Goes Molecular, pp. 471-472

Peter J. Bryant

Gravity Field over Northern Eurasia and Variations in the Strength of the Upper Mantle, pp. 473-479

Mikhail G. Kogan; Marcia K. McNutt

Beyond Nature's Chiral Pool: Enantioselective Catalysis in Industry, pp. 479-483

William A. Nugent; T. V. RajanBabu; Mark J. Burk

Research Article

A wingless-Dependent Polar Coordinate System in Drosophila Imaginal Discs, pp. 484-489

Juan Pablo Couso; Michael Bate; Alfonso Martínez-Arias

Reports

Antibody Catalysis of a Disfavored Chemical Transformation, pp. 490-493

Kim D. Janda; Charles G. Shevlin; Richard A. Lerner

Transient Turing Structures in a Gradient-Free Closed System, pp. 493-495

István Lengyel; Sándor Kádár; Irving R. Epstein

A Cationic Cesium Continuum in Zeolite X, pp. 495-497

Tao Sun; Karl Seff; Nam Ho Heo; Vitalli P. Petranovskii

Late Cenozoic Uplift of Denali and Its Relation to Relative Plate Motion and Fault Morphology, pp. 497-499

Paul G. Fitzgerald; Edmund Stump; Thomas F. Redfield

Seismic Structure of the Southern East Pacific Rise, pp. 499-503

R. S. Detrick; A. J. Harding; G. M. Kent; J. A. Orcutt; J. C. Mutter; P. Buhl

In Situ Stimulation of Aerobic PCB Biodegradation in Hudson River Sediments, pp. 503-507

M. R. Harkness; J. B. McDermott; D. A. Abramowicz; J. J. Salvo; W. P. Flanagan; M. L. Stephens; F. J. Mondello; R. J. May; J. H. Lobos; K. M. Carroll; M. J. Brennan; A. A. Bracco; K. M. Fish; G. L. Warner; P. R. Wilson; D. K. Dietrich; D. T. Lin; C. B. Morgan; W. L. Gately

Stress Protection of Transgenic Tobacco by Production of the Osmolyte Mannitol, pp. 508-510

Mitchell C. Tarczynski; Richard G. Jensen; Hans J. Bohnert

Altered Specificity of DNA-Binding Proteins with Transition Metal Dimerization Domains, pp. 510-513

Bernard Cuenoud; Alanna Schepartz

Release of Excess Amyloid β Protein from a Mutant Amyloid β Protein Precursor, pp. 514-516

Xiao-Dan Cai; Todd E. Golde; Steven G. Younkin

Sequence and Genome Organization of a Human Small Round-Structured (Norwalk-Like) Virus, pp. 516-519

Paul R. Lambden; E. Owen Caul; Charles R. Ashley; Ian N. Clarke

Activation of the Sphingomyelin Signaling Pathway in Intact EL4 Cells and in a Cell-Free System by IL-1β, pp. 519-522

Shalini Mathias; Anas Younes; Chu-Cheng Kan; Irene Orlow; Cecil Joseph; Richard N. Kolesnick

Regulation by Heme of Mitochondrial Protein Transport Through a Conserved Amino Acid Motif, pp. 522-525

Julia Tait Lathrop; Michael P. Timko

Identification of the SH3 Domain of GAP as an Essential Sequence for Ras-GAP-Mediated Signaling, pp. 525-528

Marc Duchesne; Fabien Schweighoffer; Fabienne Parker; François Clerc; Yveline Frobert; Ming Nguy Thang; Bruno Tocqué

Modulation of Anxiety and Neuropeptide Y-Y1 Receptors by Antisense Oligodeoxynucleotides, pp. 528-531

Claes Wahlestedt; Emilio Merlo Pich; George F. Koob; Frances Yee; Markus Heilig

GABA-Activated Chloride Channels in Secretory Nerve Endings, pp. 531-534

Shuanglin J. Zhang; Meyer B. Jackson

Technical Comments

Polyethylene Bags and Solar Ultraviolet Radiation, pp. 534-535

Osmund Holm-Hansen; E. Walter Helbling; Barbara B. Prézelin; Raymond C. Smith

Book Reviews

Posthumous Inspirations, pp. 536-537

The Maxwellians.

Bruce J. Hunt

Review author[s]: C. W. F. Everitt

Complexities of Feynman, pp. 537-539

Genius. The Life and Science of Richard Feynman.

James Gleick

Review author[s]: P. W. Anderson

A Pandemic Reconstrued, p. 539

AIDS and Accusation. Haiti and the Geography of Blame.

Paul Farmer

Review author[s]: Randall M. Packard

Books Received, p. 540

Back Matter (28 pp.)

Previous Issue: New Series, Vol. 259, No. 5093, Jan. 15, 1993
Next Issue: New Series, Vol. 259, No. 5095, Jan. 29, 1993

Science, New Series, Vol. 259, No. 5095, Jan. 29, 1993

Previous Issue: New Series, Vol. 259, No. 5094, Jan. 22, 1993
Next Issue: New Series, Vol. 259, No. 5096, Feb. 5, 1993

Front Matter (32 pp.)
Editorial: Basic Research (II): Organization, p. 579

Daniel E. Koshland, Jr.

Letters

Fossil Collecting and Government Regulation, pp. 581-582

Clayton E. Ray; C. S. Churcher; Clement W. Meighan

Super Collider, 2000 B.C., p. 582

John M. Rowell; Dietrich Schroeer; Jeffrey F. Friedman

Pitohui: How Toxic and to Whom?, pp. 582-583

John I. Glendinning; John P. Dumbacher; Bruce M. Beehler; Thomas F. Spande; H. Martin Garraffo; John W. Daly

Corrections and Clarifications: Getting it Together at the Synapse, p. 583
Corrections and Clarifications: Will Fermilab Find Its Future by Looking to the Stars, p. 583

Policy Forum

The Definition of Misconduct in Science: A View from NSF, pp. 584-585+647-648

Donald E. Buzzelli

ScienceScope, p. 587

Richard Stone

News

Supreme Court to Weigh Science, pp. 588-590

Eliot Marshall

Healy Stays, Fetal Tissue Ban Goes, p. 591

Christopher Anderson

Disease Gene Search Goes Big Science, pp. 591-592

Peter Aldhous

MSU Officials Criticized for Mishandling Data Dispute, pp. 592-594

Eliot Marshall

Pinatubo Global Cooling on Target, p. 594

Richard A. Kerr

New Technique Offers a Window On Bacteria's Secret Weapons, p. 595

Marcia Barinaga

Is Japan a Boon or a Burden To U.S. Industry's Leadership?, pp. 596-598

June Kinoshita

Kohl Replaces Science Minister, p. 598

Peter Aldhous

Random Samples, p. 599

Constance Holden

Special Report

The Politics of Breast Cancer, pp. 616-617

Eliot Marshall

Search for a Killer: Focus Shifts from Fat to Hormones, pp. 618-621

Eliot Marshall

Zeroing In on a Breast Cancer Susceptibility Gene, pp. 622-625

Leslie Roberts

Cellular Changes on the Route to Metastasis, pp. 626-629

Jean Marx

Perspectives

Current Approaches to Breast Cancer Prevention, pp. 630-631

Maureen Henderson

The Development of Biological Therapies for Breast Cancer, pp. 631-632

Marc E. Lippman

Hormonal Chemoprevention of Cancer in Women, pp. 633-638

Brian E. Henderson; Ronald K. Ross; Malcolm C. Pike

Demic Expansions and Human Evolution, pp. 639-646

Luigi L. Cavalli-Sforza; Paolo Menozzi; Alberto Piazza

Reports

Heliocentric Zoning of the Asteroid Belt by Aluminum-26 Heating, pp. 653-655

Robert E. Grimm; Harry Y. McSween, Jr.

Isotope Effect and Superconductivity in Metal-Doped C ₆₀, pp. 655-658

Chia-Chun Chen; Charles M. Lieber

Element-Specific Magnetic Microscopy with Circularly Polarized X-Rays, pp. 658-661

J. Stohr; Y. Wu; B. D. Hermsmeier; M. G. Samant; G. R. Harp; S. Koranda; D. Dunham; B. P. Tonner

Reaction of a Tantalum Alkylidene Complex with Dinuclear Metal Carbonyls: Formation of C₃ Ligands, pp. 661-663

Grant Proulx; Robert G. Bergman

Shock Amorphization of Cristobalite, pp. 663-666

A. J. Gratz; L. D. DeLoach; T. M. Clough; W. J. Nellis

Microstructural Observations of α-Quartz Amorphization, pp. 666-669

Kathleen J. Kingma; Charles Meade; Russell J. Hemley; Ho-kwang Mao; David R. Veblen

The Hydrolytic Water Molecule in Trypsin, Revealed by Time-Resolved Laue Crystallography, pp. 669-673

Paul T. Singer; Arne Smalås; Robert P. Carty; Walter F. Mangel; Robert M. Sweet

Structure of the Regulatory Complex of Escherichia coli III ^Glc with Glycerol Kinase, pp. 673-677

James H. Hurley; H. Rick Faber; David Worthylake; Norman D. Meadow; Saul Roseman; Donald W. Pettigrew; S. James Remington

Patchiness and Correlations in DNA Sequences, pp. 677-680

Samuel Karlin; Volker Brendel

The Skipping of Constitutive Exons in Vivo Induced by Nonsense Mutations, pp. 680-683

Harry C. Dietz; David Valle; Clair A. Francomano; Raymond J. Kendzior, Jr.; Reed E. Pyeritz; Garry R. Cutting

The Effect of Posttranslational Modifications on the Interaction of Ras2 with Adenylyl Cyclase, pp. 683-686

Yuichi Kuroda; Noboru Suzuki; Tohru Kataoka

Selection of Bacterial Virulence Genes That Are Specifically Induced in Host Tissues, pp. 686-688

Michael J. Mahan; James M. Slauch; John J. Mekalanos

CNTF Protection of Oligodendrocytes Against Natural and Tumor Necrosis Factor-Induced Death, pp. 689-692

Jean-Claude Louis; Ella Magal; Seiji Takayama; Silvio Varon

Inhibition of Neural Crest Cell Attachment by Integrin Antisense Oligonucleotides, pp. 692-695

Thomas Lallier; Marianne Bronner-Fraser

Technical Comments

A Truncated Erythropoietin Receptor and Cell Death, p. 696

Ralph Schwall; Yukio Nakamura; Hiromitsu Nakauchi

Inside AAAS, pp. 697-698

Karen Hopkin

Book Reviews

When Telephony Was Young, pp. 699-701

America Calling. A Social History of the Telephone to 1940.

Claude S. Fischer

Review author[s]: Glenn Porter

Collapsed Stellar Objects, pp. 701-702

High-Energy Radiation from Magnetized Neutron Stars.

Peter Mészáros

Review author[s]: Joseph Daugherty

Palynology, p. 702

Pollen and Spores. Patterns of Diversification.

S. Blackmore; S. H. Barnes

Review author[s]: Michael G. Simpson

Back Matter (30 pp.)

Previous Issue: New Series, Vol. 259, No. 5094, Jan. 22, 1993
Next Issue: New Series, Vol. 259, No. 5096, Feb. 5, 1993

Science, New Series, Vol. 259, No. 5096, Feb. 5, 1993

Previous Issue: New Series, Vol. 259, No. 5095, Jan. 29, 1993
Next Issue: New Series, Vol. 259, No. 5097, Feb. 12, 1993

Front Matter (20 pp.)
Editorial: Science, Technology, and National Goals, p. 743

Philip H. Abelson

Letters

Gaia in Science, p. 745

Lynn Margulis

Big Physics and New Ideas, pp. 746-747

Melvyn J. Shochet; Alvin V. Tollestrup

Corrections and Clarifications: Pot, Heroin Unlock New Areas for Neuroscience, p. 747

Policy Forum

Statistical Evaluation of DNA Fingerprinting: A Critique of the NRC's Report, pp. 748-749+837

B. Devlin; Neil Risch; Kathryn Roeder

ScienceScope, p. 751

Richard Stone

News and Comment

Agencies Spar Over Vaccine Trial, pp. 752-753

Jon Cohen

Reorganization Plan Draws Fire at NIH, pp. 753-754

Jon Cohen

Massey Leaving NSF for Top UC Job, p. 754

Chrisopher Anderson

Radio Astronomers Go Hatless, p. 754

David Lindley

Geneticists Attack NRC Report as Scientifically Flawed, pp. 755-756

Peter Aldhous

The Presidential Transition Heightens Uncertainty, pp. 756-757

Gary Taubes

Random Samples, pp. 758-759

Ivan Amato

Research News

Cell Death Studies Yield Cancer Clues, pp. 760-761

Jean Marx

Death Gives Birth to the Nervous System. But How?, pp. 762-763

Marcia Barinaga

Archaeopteryx: Early Bird Catches a Can of Worms, pp. 764-765

Virginia Morell

Catching the Wave of a New Accelerator, p. 765

Ivan Amato

Perspectives

Where Are the Nuclear Pions?, pp. 773-774

George F. Bertsch; Leonid Frankfurt; Mark Strikman

Genetic Models for Studying Cancer Susceptibility, pp. 774-775

Stephen H. Friend

Biological Control of Crystal Texture: A Widespread Strategy for Adapting Crystal Properties to Function, pp. 776-779

Amir Berman; Jonathan Hanson; Leslie Leiserowitz; Thomas F. Koetzle; Stephen Weiner; Lia Addadi

Synaptic Vesicle Phosphoproteins and Regulation of Synaptic Function, pp. 780-785

Paul Greengard; Flavia Valtorta; Andrew J. Czernik; Fabio Benfenati

Reports

Magnesium and Calcium Aluminate Liquids: In Situ High-Temperature ²⁷ Al NMR Spectroscopy, pp. 786-788

B. T. Poe; P. F. McMillan; B. Coté; D. Massiot; J. P. Coutures

Noble Gas Partitioning Between Metal and Silicate Under High Pressures, pp. 788-790

J. Matsuda; M. Sudo; M. Ozima; K. Ito; O. Ohtaka; E. Ito

Evidence from Claw Geometry Indicating Arboreal Habits of Archaeopteryx, pp. 790-793

Alan Feduccia

A High-Temperature Superconducting Receiver for Nuclear Magnetic Resonance Microscopy, pp. 793-795

R. D. Black; T. A. Early; P. B. Roemer; O. M. Mueller; A. Mogro-Campero; L. G. Turner; G. A. Johnson

Formation of an Fe(III)-Tyrosinate Complex During Biomineralization of H-Subunit Ferritin, pp. 796-798

Geoffrey S. Waldo; Jinshu Ling; Joann Sanders-Loehr; Elizabeth C. Theil

Molecular Positional Order in Langmuir-Blodgett Films by Atomic Force Microscopy, pp. 798-801

L. Bourdieu; O. Ronsin; D. Chatenay

Mediation of Sulfur Speciation by a Black Sea Facultative Anaerobe, pp. 801-803

K. A. Perry; J. E. Kostka; G. W. Luther III; K. H. Nealson

Multiple Evolutionary Origins of Magnetotaxis in Bacteria, pp. 803-806

Edward F. DeLong; Richard B. Frankel; Dennis A. Bazylinski

Probing the Structure and Mechanism of Ras Protein with an Expanded Genetic Code, pp. 806-809

Hyun-Ho Chung; David R. Benson; Peter G. Schultz

Reduction in Size of the Myotonic Dystrophy Trinucleotide Repeat During Transmission, pp. 809-812

Kim L. O'Hoy; Catherine Tsilfidis; Mani S. Mahadevan; Catherine E. Neville; Juana Barceló; Alasdair G. W. Hunter; Robert G. Korneluk

Editing of Transfer RNAs in Acanthamoeba castellanii Mitochondria, pp. 812-816

Kim M. Lonergan; Michael W. Gray

Tumor Suppression in Xiphophorus by an Accidentally Acquired Promoter, pp. 816-819

Dieter Adam; Nicola Dimitrijevic; Manfred Schartl

Multiple Output Channels in the Basal Ganglia, pp. 819-821

John E. Hoover; Peter L. Strick

Restoration of T Cell Development in RAG-2-Deficient Mice by Functional TCR Transgenes, pp. 822-825

Yoichi Shinkai; Shigeo Koyasu; Kei-ichi Nakayama; Kenneth M. Murphy; Dennis Y. Loh; Ellis L. Reinherz; Frederick W. Alt

β-Adrenergic Receptor Kinase-2 and β-Arrestin-2 as Mediators of Odorant-Induced Desensitization, pp. 825-829

Ted M. Dawson; Jeffrey L. Arriza; Donna E. Jaworsky; Felice F. Borisy; Håvard Attramadal; Robert J. Lefkowitz; Gabriele V. Ronnett

Role of the Acylated Amino Terminus of Recoverin in Ca ²⁺ -Dependent Membrane Interaction, pp. 829-832

Alexander M. Dizhoor; Ching-Kang Chen; Elena Olshevskaya; Valeria V. Sinelnikova; Pavel Phillipov; James B. Hurley

Selectivity in Signal Transduction Determined by γ Subunits of Heterotrimeric G Proteins, pp. 832-834

Christiane Kleuss; Hans Scherübl; Jürgen Hescheler; Günter Schultz; Burghardt Wittig

Technical Comments

Algae and Oxygen in Earth's Ancient Atmosphere, p. 835

James F. Kasting; B. Runnegar

Laser-Enhanced NMR Spectroscopy: Theoretical Considerations, pp. 835-836

Robert A. Harris; Ignacio Tinoco, Jr.; Warren S. Warren; S. Mayr; D. Goswami; A. P. West, Jr.

Book Reviews

Mertonian Concessions, pp. 839-841

Making Science. Between Nature and Society.

Stephen Cole

Review author[s]: Steven Shapin

General Inventor, pp. 841-843

Alexanderson. Pioneer in American Electrical Engineering.

James E. Brittain

Review author[s]: W. Bernard Carlson

Female Functioning, pp. 843-844

Periods. From Menarche to Menopause.

Sharon Golub

Menstrual Health in Women's Lives.

Alice J. Dan; Linda L. Lewis

Review author[s]: Mary Brown Parlee

A Century After Cajal, pp. 845-846

The Cerebellum Revisited.

Rodolfo Llinás; Constantino Sotelo

Review author[s]: Allan M. Smith

Books Received, pp. 846-847

Back Matter (17 pp.)

Previous Issue: New Series, Vol. 259, No. 5095, Jan. 29, 1993
Next Issue: New Series, Vol. 259, No. 5097, Feb. 12, 1993

Science, New Series, Vol. 259, No. 5097, Feb. 12, 1993

Previous Issue: New Series, Vol. 259, No. 5096, Feb. 5, 1993
Next Issue: New Series, Vol. 259, No. 5098, Feb. 19, 1993

Front Matter (22 pp.)
Editorial: Evolution of Atmospheres, p. 875

Brooks Hanson

Letters

Asteroid or Volcano: Have the Volcanists Been Heard?, p. 877

Dewey M. McLean; Daniel E. Koshland, Jr.

Basic Research and Society, pp. 877-878

Robin W. Briehl; Robert G. Sachs

Correction: A Li-Fraumeni Syndrome p53 Mutation, p. 878

David Malkin; Stephen H. Friend

Corrections and Clarifications: Drawing a Bead on Superdense Data Storage, p. 878
Corrections and Clarifications: Top HHS Lawyer Seeks to Block NIH, p. 878
ScienceScope, p. 883

Richard Stone

News and Comment

Hughes' Tough Stand on Industry Ties, pp. 884-886

Christopher Anderson

A Shot in the Arm for TB Research, p. 886

Traci Watson

NASA Stakes its Reputation on Fix for Hubble Telescope, pp. 887-889

Faye Flam

Scripps-Sandoz Deal Comes Under Fire, p. 889

Christopher Anderson

Shalala Backs Reorganization, p. 889

Jon Cohen

Research News

Will Future Computers be All Wet?, pp. 890+891-892

David Bradley

Chemists Work Their Way from Pores to Riches, p. 891

Ivan Amato

Unexpected Intelligence Turns up in a Cellular Gel, pp. 893-894

John Travis

Mathematicians Gather to Play the Numbers Game, pp. 894-895

Barry Cipra

Cell Communication Failure Leads to Immune Disorder, pp. 896-897

Jean Marx

Random Samples, p. 898

Faye Flam

Special Section: Evolution of Atmospheres

[Introduction], p. 905

News

Is the Geological Past a Key to the (Near) Future?, pp. 906-908

Elizabeth Culotta

Searching for Clues to Ancient Carbon Dioxide, pp. 908-909

Tim Appenzeller

An `Outrageous Hypothesis' for Mars: Episodic Oceans, pp. 910-911

Richard A. Kerr

Earth Scientists Look NASA's Gift Horse in the Mouth, pp. 912-914

Gary Taubes

Atmospheric Evolution of the Terrestrial Planets, pp. 915-920

Donald M. Hunten

Earth's Early Atmosphere, pp. 920-926

James F. Kasting

The Ice Record of Greenhouse Gases, pp. 926-934

D. Raynaud; J. Jouzel; J. M. Barnola; J. Chappellaz; R. J. Delmas; C. Lorius

The Global Carbon Dioxide Budget, pp. 934-941

Eric T. Sundquist

Perspectives

The Pluses of Subtraction, pp. 942-943

Richard M. Myers

RNA Polymerase Marching Backward, pp. 944-945

George A. Kassavetis; E. Peter Geiduschek

Research Article

Cloning the Differences Between Two Complex Genomes, pp. 946-951

Nikolai Lisitsyn; Natalya Lisitsyn; Michael Wigler

Reports

Existence of a Flat Phase in Red Cell Membrane Skeletons, pp. 952-955

Christoph F. Schmidt; Karel Svoboda; Ning Lei; Irena B. Petsche; Lonny E. Berman; Cyrus R. Safinya; Gary S. Grest

Photoinduced Polymerization of Solid C ₆₀ Films, pp. 955-957

A. M. Rao; Ping Zhou; Kai-An Wang; G. T. Hager; J. M. Holden; Ying Wang; W.-T. Lee; Xiang-Xin Bi; P. C. Eklund; D. S. Cornett; M. A. Duncan; I. J. Amster

Electrochemical Processing of Conducting Polymer Fibers, pp. 957-960

Shulong Li; Christopher W. Macosko; Henry S. White

Colicin E1 Binding to Membranes: Time-Resolved Studies of Spin-Labeled Mutants, pp. 960-963

Yeon-Kyun Shin; Cyrus Levinthal; Françoise Levinthal; Wayne L. Hubbell

The Secretory Granule Matrix: A Fast-Acting Smart Polymer, pp. 963-965

Chaya Nanavati; Julio M. Fernandez

Structure of the Thiamine- and Flavin-Dependent Enzyme Pyruvate Oxidase, pp. 965-967

Yves A. Muller; Georg E. Schulz

Deletion of IRF-1, Mapping to Chromosome 5q31.1, in Human Leukemia and Preleukemic Myelodysplasia, pp. 968-971

Cheryl L. Willman; Cordelia E. Sever; Maria G. Pallavicini; Hisashi Harada; Nobuyuki Tanaka; Marilyn L. Slovak; Hitomi Yamamoto; Kenji Harada; Timothy C. Meeker; Alan F. List; Tadatsugu Taniguchi

Anti-Oncogenic and Oncogenic Potentials of Interferon Regulatory Factors-1 and -2, pp. 971-974

Hisashi Harada; Motoo Kitagawa; Nobuyuki Tanaka; Hitomi Yamamoto; Kenji Harada; Masahiko Ishihara; Tadatsugu Taniguchi

"Infectious" Transplantation Tolerance, pp. 974-977

Shixin Qin; Stephen P. Cobbold; Heather Pope; James Elliott; Dimitris Kioussis; Joanna Davies; Herman Waldmann

Carboxyl Methylation of Ras-Related Proteins During Signal Transduction in Neutrophils, pp. 977-980

Mark R. Philips; Michael H. Pillinger; Roland Staud; Craig Volker; Melvin G. Rosenfeld; Gerald Weissmann; Jeffry B. Stock

Altered Prevalence of Gating Modes in Neurotransmitter Inhibition of N-Type Calcium Channels, pp. 980-984

Anne H. Delcour; Richard W. Tsien

Shutdown of Class Switch Recombination by Deletion of a Switch Region Control Element, pp. 984-987

Steffen Jung; Klaus Rajewsky; Andreas Radbruch

An Adenovirus Vector for Gene Transfer into Neurons and Glia in the Brain, pp. 988-990

G. Le Gal La Salle; J. J. Robert; S. Berrard; V. Ridoux; L. D. Stratford-Perricaudet; M. Perricaudet; J. Mallet

CD40 Ligand Gene Defects Responsible for X-Linked Hyper-IgM Syndrome, pp. 990-993

R. Cutler Allen; Richard J. Armitage; Mary Ellen Conley; Howard Rosenblatt; Nancy A. Jenkins; Neal G. Copeland; Mary A. Bedell; Susanne Edelhoff; Christine M. Disteche; Denise K. Simoneaux; William C. Fanslow; John Belmont; Melanie K. Spriggs

Book Reviews

Shifts and Overthrows, pp. 995-996

Revolutions in Mathematics.

Donald Gillies

Review author[s]: John McCleary

AEC and Critics, pp. 996-997

Containing the Atom. Nuclear Regulation in a Changing Environment, 1963-1971.

J. Samuel Walker

Review author[s]: James M. Jasper

Books Received, p. 997

Back Matter (95 pp.)

Previous Issue: New Series, Vol. 259, No. 5096, Feb. 5, 1993
Next Issue: New Series, Vol. 259, No. 5098, Feb. 19, 1993

Science, New Series, Vol. 259, No. 5098, Feb. 19, 1993

Previous Issue: New Series, Vol. 259, No. 5097, Feb. 12, 1993
Next Issue: New Series, Vol. 259, No. 5099, Feb. 26, 1993

Front Matter (46 pp.)
Editorial: Get-Rich-Quick Science, p. 1103

Daniel E. Koshland, Jr.

Letters

Minorities in Science: The Dialogue, pp. 1105-1109

Warren V. Sherman; Catalina Fresquez; Frederick C. Greenwood; Healani Chang; Howard H. Garrison; Allen B. Clarkson, Jr.; George Campbell Jr.; Elvira Doman; Derrick T. Brazill; Steven J. Mack; Paul Evans; James McCarter; Matthew Schreiber; Rajiv Bhatnagar; John Knox; Z. Renee Sung; H. V. Wong; Joseph D. Ciparick; Gertrude Wittig

ScienceScope, p. 1111

Richard Stone

News and Comment

A `Manhattan Project' for AIDS?, pp. 1112-1114

Jon Cohen

Jack Gibbons: Plugging Into the Power Structure, pp. 1115-1116

Christopher Anderson; Colin Norman

A Worldly Approach to a New Accelerator, p. 1116

Gary Taubes

Brown Turns Up the Heat on Pork, p. 1117

Colin Norman

Pasteur Notebooks Reveal Deception, p. 1117

Christopher Anderson

Random Samples, pp. 1118-1119

Christopher Anderson

Research News

Parkfield Quakes Skip a Beat, pp. 1120-1122

Richard A. Kerr

Shiny Molecules Gain New Luster, p. 1122

Ivan Amato

Probing the Unsolved Mysteries of the Deep, pp. 1123-1124

John Travis

Déjà Vu Guides the Way to New Antimicrobial Steroid, p. 1125

Richard Stone

Perspectives

Glowing Avalanches: New Research on Volcanic Density Currents, pp. 1130-1131

Greg A. Valentine; Richard V. Fisher

Mineralocorticoids, Glucocorticoids, Receptors and Response Elements, pp. 1132-1133

John W. Funder

A Complete Second Gut Induced by Transplanted Micromeres in the Sea Urchin Embryo, pp. 1134-1138

Andrew Ransick; Eric H. Davidson

Research Article

Live Iron-60 in the Early Solar System, pp. 1138-1142

A. Shukolyukov; G. W. Lugmair

Reports

Formaldehyde and Organic Molecule Production in Astrophysical Ices at Cryogenic Temperatures, pp. 1143-1145

W. A. Schutte; L. J. Allamandola; S. A. Sandford

Specific Heat and Thermal Conductivity of Solid Fullerenes, pp. 1145-1148

J. R. Olson; K. A. Topp; R. O. Pohl

Mid-Depth Circulation of the Subpolar North Atlantic During the Last Glacial Maximum, pp. 1148-1152

D. W. Oppo; S. J. Lehman

Order-Disorder Transition in Polycrystalline C ₆₀ Films, pp. 1152-1154

Kelly Akers; Kejian Fu; Peng Zhang; Martin Moskovits

The Nonhelical Structure of Antifreeze Protein Type III, pp. 1154-1157

Frank D. Sönnichsen; Brian D. Sykes; Heman Chao; Peter L. Davies

Identification of a Ten-Amino Acid Proline-Rich SH3 Binding Site, pp. 1157-1161

Ruibao Ren; Bruce J. Mayer; Piera Cicchetti; David Baltimore

Mineralocorticoid and Glucocorticoid Receptor Activities Distinguished by Nonreceptor Factors at a Composite Response Element, pp. 1161-1165

David Pearce; Keith R. Yamamoto

Progression to Diabetes in Nonobese Diabetic (NOD) Mice with Transgenic T Cell Receptors, pp. 1165-1169

Myra A. Lipes; Anthony Rosenzweig; Kut-Nie Tan; Gary Tanigawa; Dan Ladd; Jonathan G. Seidman; George S. Eisenbarth

A Functional Role for GTP-Binding Proteins in Synaptic Vesicle Cycling, pp. 1169-1172

S. D. Hess; P. A. Doroshenko; G. J. Augustine

Phosphorylation and Modulation of a Kainate Receptor (GluR6) by cAMP- Dependent Protein Kinase, pp. 1173-1175

Lu-Yang Wang; Franco A. Taverna; Xi-Ping Huang; John F. MacDonald; David R. Hampson

Book Reviews

McClintock Myths, pp. 1206-1208

The Dynamic Genome. Barbara McClintock's Ideas in the Century of Genetics.

Nina Fedoroff; David Botstein

Review author[s]: Allan C. Spradling

Insects Recaptured, p. 1208

The Treatise on Invertebrate Paleontology. Part R, Arthropoda 4. Vols. 3 and 4. Superclass Hexapoda.

F. M. Carpenter

Review author[s]: Howard E. Evans

Progress in Physiology, pp. 1208-1209

A History of Gastric Secretion and Digestion. Experimental Studies to 1975.

Horace W. Davenport

Review author[s]: Eugene Straus

Spectra at a Distance, pp. 1209-1210

Spectroscopy of the Earth's Atmosphere and Interstellar Medium.

K. Narahari Rao; Alfons Weber

Review author[s]: Jack S. Margolis

Books Received, p. 1210

Back Matter (14 pp.)

Previous Issue: New Series, Vol. 259, No. 5097, Feb. 12, 1993
Next Issue: New Series, Vol. 259, No. 5099, Feb. 26, 1993

Science, New Series, Vol. 259, No. 5099, Feb. 26, 1993

Previous Issue: New Series, Vol. 259, No. 5098, Feb. 19, 1993
Next Issue: New Series, Vol. 259, No. 5100, Mar. 5, 1993

Front Matter (35 pp.)
Editorial: Pesticides and Food, p. 1235

Philip H. Abelson

Letters

Funding the SSC, pp. 1237-1238

T. H. Geballe; J. M. Rowell

Smitten by Quail, pp. 1238-1239

David B. Berkowitz

The Quality of Homoeosis, pp. 1239-1240

Z. Renee Sung

Splicer RNAs, p. 1240

Joan A. Steitz

ScienceScope, p. 1243

Richard Stone

News and Comment

Clinton's Technology Policy Emerges, pp. 1244-1245

Christopher Anderson

Publication by Electronic Mail Takes Physics by Storm, pp. 1246-1248

Gary Taubes

An Array of Science from Mitochondrial Eve to EUVE, pp. 1249-1252

Ann Gibbons; John Travis; Steven Dickman

New Meetings Tackle The Knowledge Conundrum, pp. 1253-1255

Anne Simon Moffat

Random Samples, p. 1256

Traci Watson

Research News

The Cell's Nucleus Shapes Up, pp. 1257-1258+1259

Michelle Hoffman

Looking for Cancer in Nuclear Matrix Proteins, p. 1258

John Travis

Analytical Titans Gather at Pittcon to Predict the Future, pp. 1260-1261

Ivan Amato

Battle Lines Shift in the Great Cosmic Distance Dispute, pp. 1262-1263

Faye Flam

MS Study Yields Mixed Results, p. 1263

Carol Kaesuk Yoon

Perspective

GTP Hydrolysis in Protein Synthesis: Two for Tu?, pp. 1264-1265

Paul Schimmel

Mediterranean Outflow Mixing and Dynamics, pp. 1277-1282

James F. Price; Molly O'Neil Baringer; Rolf G. Lueck; Gregory C. Johnson; Isabel Ambar; Gregorio Parrilla; Alain Cantos; Maureen A. Kennelly; Thomas B. Sanford

Simple Systems That Exhibit Self-Directed Replication, pp. 1282-1287

James A. Reggia; Steven L. Armentrout; Hui-Hsien Chou; Yun Peng

Research Article

Crystal Structure of a Synthetic Triple-Stranded α-Helical Bundle, pp. 1288-1293

Brett Lovejoy; Seunghyon Choe; Duilio Cascio; Donald K. McRorie; William F. DeGrado; David Eisenberg

Reports

The Chaotic Obliquity of Mars, pp. 1294-1297

Jihad Touma; Jack Wisdom

Lidar Observations of the Meteoric Deposition of Mesospheric Metals, pp. 1297-1300

Timothy J. Kane; Chester S. Gardner

Isomers of Small Carbon Cluster Anions: Linear Chains with up to 20 Atoms, pp. 1300-1302

Gert von Helden; Paul R. Kemper; Nigel G. Gotts; Michael T. Bowers

A Mixed-Valent Polyiron Oxo Complex That Models the Biomineralization of the Ferritin Core, pp. 1302-1305

Kingsley L. Taft; Georgia C. Papaefthymiou; Stephen J. Lippard

Identification of a Second Dynamic State During Stick-Slip Motion, pp. 1305-1308

Hisae Yoshizawa; Patricia McGuiggan; Jacob Israelachvili

Three-Dimensional Instabilities of Mantle Convection with Multiple Phase Transitions, pp. 1308-1311

S. Honda; D. A. Yuen; S. Balachandar; D. Reuteler

Toward a Model for the Interaction Between Elongation Factor Tu and the Ribosome, pp. 1311-1314

Albert Weijland; Andrea Parmeggiani

Inhibition of Rev-Mediated HIV-1 Expression by an RNA Binding Protein Encoded by the Interferon-Inducible 9-27 Gene, pp. 1314-1318

Pantelis Constantoulakis; Mel Campbell; Barbara K. Felber; Georgios Nasioulas; Elena Afonina; George N. Pavlakis

The Cloning of PIG-A, a Component in the Early Step of GPI-Anchor Biosynthesis, pp. 1318-1320

Toshio Miyata; Junji Takeda; Yoshiyasu Iida; Norio Yamada; Norimitsu Inoue; Minoru Takahashi; Kenji Maeda; Teruo Kitani; Taroh Kinoshita

Double-Blind Pilot Trial of Oral Tolerization with Myelin Antigens in Multiple Sclerosis, pp. 1321-1324

Howard L. Weiner; Glenn A. Mackin; Makoto Matsui; E. John Orav; Samia J. Khoury; David M. Dawson; David A. Hafler

Association Between Brain Temperature and Dentate Field Potentials in Exploring and Swimming Rats, pp. 1324-1326

Edvard Moser; Iacob Mathiesen; Per Andersen

Higher Level Organization of Individual Gene Transcription and RNA Splicing, pp. 1326-1330

Yigong Xing; Carol V. Johnson; Paul R. Dobner; Jeanne Bentley Lawrence

A Three-Dimensional View of Precursor Messenger RNA Metabolism Within the Mammalian Nucleus, pp. 1330-1335

Kenneth C. Carter; Douglas Bowman; Walter Carrington; Kevin Fogarty; John A. McNeil; Fredric S. Fay; Jeanne Bentley Lawrence

Technical Comments

The Role of Water in Hemoglobin Function and Stability, pp. 1335-1336

D. Bulone; P. L. San Biagio; M. B. Palma-Vittorelli; M. U. Palma; Marcio F. Colombo; Donald C. Rau; V. Adrian Parsegian

Book Reviews

Retrospective on Hanford, pp. 1348-1349

On the Home Front. The Cold War Legacy of the Hanford Nuclear Site.

Michele Stenehjem Gerber

Review author[s]: Bruce Hevly

S-Curves Everywhere, pp. 1349-1350

Predictions. Society's Telltale Signature Reveals the Past and Forecasts the Future.

Theodore Modis

Review author[s]: Kenneth C. Land

Geofractology, pp. 1350-1351

Fractal Models in the Earth Sciences.

G. Korvin

Review author[s]: Charles Sammis

Back Matter (17 pp.)

Previous Issue: New Series, Vol. 259, No. 5098, Feb. 19, 1993
Next Issue: New Series, Vol. 259, No. 5100, Mar. 5, 1993

Science, New Series, Vol. 259, No. 5100, Mar. 5, 1993

Previous Issue: New Series, Vol. 259, No. 5099, Feb. 26, 1993
Next Issue: New Series, Vol. 259, No. 5101, Mar. 12, 1993

Front Matter (17 pp.)
Editorial: Basic Research (III): Priorities, p. 1379

Daniel E. Koshland, Jr.

Letters

Pondering Greenhouse Policy, pp. 1381-1384

Stephen H. Schneider; Hadi Dowlatabadi; Lester B. Lave; Michael Oppenheimer; William D. Nordhaus

Priority Envy, p. 1384

James L. Sutton

Corrections and Clarifications: Glowing Avalanches: New Research on Volcanic Density Currents, p. 1384
Corrections and Clarifications: An Optimal Transition Path for Controlling Greenhouse Gases, p. 1384
ScienceScope, p. 1387

Richard Stone

News and Comment

Bernadine Healy Bows Out, pp. 1388-1389

Jon Cohen

Animal Regulations Overturned, p. 1389

Traci Watson

Tropical Deforestation: Not Just a Problem in Amazonia, p. 1390

Peter Aldhous

A Speeding Ticket for NIH's Controversial Cancer Star, pp. 1391-1392

Christopher Anderson

Space Woes Begin to Take a Toll at UCSF, pp. 1392-1393

Marcia Barinaga

Gene Linked to Lou Gehrig's Disease, p. 1393

Jean Marx

Special Report

Toxicology Goes Molecular, pp. 1394-1396+1398

Eliot Marshall

Hot Field: Neurotoxicology, p. 1397

Richard Stone

Ken Olden Heals NIEHS's `Split Brain', pp. 1398-1399

R. S.

Research News

Did Venus Hiccup or Just Run Down?, pp. 1400-1401

Richard A. Kerr

What Might Cause Parasites to Become More Virulent, p. 1402

Carol Kaesuk Yoon

Long Search for Sea Urchin Sperm Receptor Pays Off, pp. 1403-1404

Peter Aldhous

If You're Stumped, Try Something Harder, p. 1404

Barry Cipra

Random Samples, p. 1405

Christopher Anderson

Perspective

Cells in Stress: Transcriptional Activation of Heat Shock Genes, pp. 1409-1410

Richard I. Morimoto

Radiative Climate Forcing by the Mount Pinatubo Eruption, pp. 1411-1415

P. Minnis; E. F. Harrison; L. L. Stowe; G. G. Gibson; F. M. Denn; D. R. Doelling; W. L. Smith, Jr.

Molecular Matchmakers, pp. 1415-1420

Aziz Sancar; John E. Hearst

Research Article

Sea Urchin Egg Receptor for Sperm: Sequence Similarity of Binding Domain and hsp70, pp. 1421-1425

Kathleen R. Foltz; Jacqueline S. Partin; William J. Lennarz

Reports

Crystal Structure and Optical Properties of Cd ₃₂ S ₁₄ (SC₆H₅) ₃₆ ⋅DMF₄, a Cluster with a 15 Angstrom CdS Core, pp. 1426-1428

N. Herron; J. C. Calabrese; W. E. Farneth; Y. Wang

Stable Compounds of Helium and Neon: He@C ₆₀ and Ne@C ₆₀, pp. 1428-1430

Martin Saunders; Hugo A. Jiménez-Vázquez; R. James Cross; Robert J. Poreda

On the Application of the Minimal Principle to Solve Unknown Structures, pp. 1430-1433

Russ Miller; George T. DeTitta; Rob Jones; David A. Langs; Charles M. Weeks; Herbert A. Hauptman

A 2000-Year Tree Ring Record of Annual Temperatures in the Sierra Nevada Mountains, pp. 1433-1436

Louis A. Scuderi

Export of North American Ozone Pollution to the North Atlantic Ocean, pp. 1436-1439

David D. Parrish; John S. Holloway; Michael Trainer; Paul C. Murphy; Gerry L. Forbes; Fred C. Fehsenfeld

Fossilization of Soft Tissue in the Laboratory, pp. 1439-1442

Derek E. G. Briggs; Amanda J. Kear

Population Structure and the Evolution of Virulence in Nematode Parasites of Fig Wasps, pp. 1442-1445

Edward Allen Herre

Structure-Based Discovery of Inhibitors of Thymidylate Synthase, pp. 1445-1450

Brian K. Shoichet; Robert M. Stroud; Daniel V. Santi; Irwin D. Kuntz; Kathy M. Perry

Deficiency in Rhabdomyosarcomas of a Factor Required for MyoD Activity and Myogenesis, pp. 1450-1453

Stephen J. Tapscott; Mathew J. Thayer; Harold Weintraub

Antagonism of Catecholamine Receptor Signaling by Expression of Cytoplasmic Domains of the Receptors, pp. 1453-1457

Louis M. Luttrell; Jacek Ostrowski; Susanna Cotecchia; Humphrey Kendall; Robert J. Lefkowitz

T_H1 and T_H2 Cell Antigen Receptors in Experimental Leishmaniasis, pp. 1457-1460

Steven L. Reiner; Zhi-En Wang; Farah Hatam; Phillip Scott; Richard M. Locksley

Inhibition of Human Colon Cancer Growth by Antibody-Directed Human LAK Cells in SCID Mice, pp. 1460-1463

Hiroshi Takahashi; Tetsuya Nakada; Isabelle Puisieux

Optical Time-of-Flight and Absorbance Imaging of Biologic Media, pp. 1463-1466

David A. Benaron; David K. Stevenson

Requirement for a GTPase-Activating Protein in Vesicle Budding from the Endoplasmic Reticulum, pp. 1466-1468

Tohru Yoshihisa; Charles Barlowe; Randy Schekman

Technical Comments

The Energy Density of Water and Ice Nucleation, pp. 1469-1470

Larry Wilen; M. Lahav; M. Eisenstein; L. Leiserowitz

HTLV-1 Provirus and Mycosis Fungoides, pp. 1470-1471

S. J. Whittaker; L. Luzzatto; A. Bazarbachi; F. Saal; L. Laroche; B. Flageul; J. Périès; H. de Thé; William W. Hall

Book Reviews

A Transition Examined, pp. 1473-1474

The Origins of Agriculture. An International Perspective.

C. Wesley Cowan; Patty Jo Watson

Review author[s]: Joy McCorriston

A Colonial-Era Science, pp. 1474-1475

The Savage Within. The Social History of British Anthropology, 1885-1945.

Henrika Kuklick

Review author[s]: Frank Spencer

Questions for Selectionists, pp. 1475-1476

Natural Selection. Domains, Levels, and Challenges.

George C. Williams

Review author[s]: Stephen C. Stearns

Genetics by Nation, pp. 1476-1477

The History and Development of Human Genetics. Progress in Different Countries.

Krishna R. Dronamraju

Review author[s]: Arno G. Motulsky

Books Received, p. 1477

Back Matter (31 pp.)

Previous Issue: New Series, Vol. 259, No. 5099, Feb. 26, 1993
Next Issue: New Series, Vol. 259, No. 5101, Mar. 12, 1993

Science, New Series, Vol. 259, No. 5101, Mar. 12, 1993

Previous Issue: New Series, Vol. 259, No. 5100, Mar. 5, 1993
Next Issue: New Series, Vol. 259, No. 5102, Mar. 19, 1993

Front Matter (20 pp.)
Editorial: Frontiers in Chemistry, p. 1519

John I. Brauman

Letters

A Reviewer's Obligation, p. 1521

Allen J. Bard

Priorities in Research, p. 1521

Albert B. Sabin

Availability of Taq Polymerase, pp. 1521-1522

Ronald Sederoff; H. Walter Haeussler

Learning to Save Lives, p. 1522

Paul Meier

The Search for Intelligence, pp. 1522-1523

Ernst Mayr

Sequence Correction, p. 1523

Isao Kitajima; Toshiya Shinohara; James Bilakovics; David A. Brown; Xiao Xu; Michael Nerenberg

ScienceScope, p. 1527

Richard Stone

News and Comment

Childhood Vaccines: The R&D Factor, pp. 1528-1529

Jon Cohen

Chimp Colony Offered for Quick Sale, p. 1530

Jon Cohen

Fallout From Paper on Working Mothers, pp. 1530-1531

Robert Crease

Mourning the Plight of the Condor, p. 1531

Gary Taubes

Old School Ties: Watson, Crick, and 40 Years of DNA, pp. 1532-1533

Stephen S. Hall

Deep-Sea Debate Pits Alvin Against Jason, pp. 1534-1536

John Travis

Funding Bonanza Splits Biologists, p. 1536

Peter Aldhous

Random Samples, p. 1537

Faye Flam

Research News

The Slow Birth of Green Chemistry, pp. 1538-1541

Ivan Amato

New Marker for Nerve Damage, p. 1541

Richard Stone

Theorists to the Quantum Mechanical Wave: `Get Real', pp. 1542-1543

David H. Freedman

Second Crater Points to Killer Comets, p. 1543

Richard A. Kerr

Perspective

Paths to Higher Temperature Superconductors, pp. 1550-1551

Theodore H. Geballe

Frontiers in Chemistry

Organorhenium Chemistry, pp. 1552-1558

Charles P. Casey

Turning Down the Heat: Design and Mechanism in Solid-State Synthesis, pp. 1558-1564

Andreas Stein; Steven W. Keller; Thomas E. Mallouk

Phosphorodithioate DNA as a Potential Therapeutic Drug, pp. 1564-1570

W. S. Marshall; M. H. Caruthers

Molecular Interactions and Hydrogen Bond Tunneling Dynamics: Some New Perspectives, pp. 1570-1575

Richard J. Saykally; Geoffrey A. Blake

Electronic Structure Contributions to Function in Bioinorganic Chemistry, pp. 1575-1581

Edward I. Solomon; Michael D. Lowery

Coherent Control of Quantum Dynamics: The Dream Is Alive, pp. 1581-1589

Warren S. Warren; Herschel Rabitz; Mohammed Dahleh

Reports

Impurity-Driven Cone Formation During Laser Sputtering of Graphite, pp. 1590-1592

Douglas J. Krajnovich; José E. Vázquez; Richard J. Savoy

Phosphorus: An Elemental Catalyst for Diamond Synthesis and Growth, pp. 1592-1593

Minoru Akaishi; Hisao Kanda; Shinobu Yamaoka

Cyclocarbon Coalescence: Mechanisms for Tailor-Made Fullerene Formation, pp. 1594-1596

Stephen W. McElvany; Mark M. Ross; Nancy S. Goroff; Francois Diederich

An Inorganic Double Helix: Hydrothermal Synthesis, Structure, and Magnetism of Chiral [(CH₃)₂NH₂]K₄[V ₁₀ O ₁₀ (H₂O)₂(OH)₄(PO ₄)₇]⋅4H₂O, pp. 1596-1599

Victoria Soghomonian; Qin Chen; Robert C. Haushalter; Jon Zubieta; Charles J. O'Connor

Fullerenes from a Fulgurite, pp. 1599-1601

Terry K. Daly; Peter R. Buseck; Peter Williams; Charles F. Lewis

Buckytubes and Derivatives: Their Growth and Implications for Buckyball Formation, pp. 1601-1604

V. P. Dravid; X. Lin; Y. Wang; X. K. Wang; A. Yee; J. B. Ketterson; R. P. H. Chang

Betacellulin: A Mitogen from Pancreatic β Cell Tumors, pp. 1604-1607

Y. Shing; G. Christofori; D. Hanahan; Y. Ono; R. Sasada; K. Igarashi; J. Folkman

SH2-Containing Phosphotyrosine Phosphatase as a Target of Protein-Tyrosine Kinases, pp. 1607-1611

Gen-Sheng Feng; Chi-Chung Hui; Tony Pawson

Activation of a Phosphotyrosine Phosphatase by Tyrosine Phosphorylation, pp. 1611-1614

Wolfgang Vogel; Reiner Lammers; Jiaoti Huang; Axel Ullrich

Expression Cloning and Signaling Properties of the Rat Glucagon Receptor, pp. 1614-1616

Laura J. Jelinek; Si Lok; Gary B. Rosenberg; Robert A. Smith; Francis J. Grant; Shaula Biggs; Peggie A. Bensch; Joseph L. Kuijper; Paul O. Sheppard; Cindy A. Sprecher; Patrick J. O'Hara; Don Foster; Kathleen M. Walker; Lennie H. J. Chen; Patricia A. McKernan; Wayne Kindsvogel

Ultrastructural Evidence for Hair Cell Regeneration in the Mammalian Inner Ear, pp. 1616-1619

Andrew Forge; Lin Li; Jeffrey T. Corwin; Graham Nevill

Regenerative Proliferation in Inner Ear Sensory Epithelia from Adult Guinea Pigs and Humans, pp. 1619-1622

Mark E. Warchol; Paul R. Lambert; Bradley J. Goldstein; Andrew Forge; Jeffrey T. Corwin

Effect of PU.1 Phosphorylation on Interaction with NF-EM5 and Transcriptional Activation, pp. 1622-1625

Jagan M. R. Pongubala; Charles Van Beveren; Sujatha Nagulapalli; Michael J. Klemsz; Scott R. McKercher; Richard A. Maki; Michael L. Atchison

Technical Comments

Dating of the Devils Hole Calcite Vein, pp. 1626-1627

R. Lawrence Edwards; Christina D. Gallup; K. R. Ludwig; K. R. Simmons; I. J. Winograd; B. J. Szabo; A. C. Riggs

Social Learning in Invertebrates, pp. 1627-1629

Gerald B. Biederman; Valerie A. Davey; M. D. Suboski; D. Muir; D. Hall; Graziano Fiorito

Book Reviews

Endogenous Dangers, pp. 1630-1631

Stress, the Aging Brain, and the Mechanisms of Neuron Death.

Robert M. Sapolsky

Review author[s]: Robert S. Sloviter

Botanical Defenses, pp. 1631-1632

Plant Resistance to Herbivores and Pathogens. Ecology, Evolution, and Genetics.

Robert S. Fritz; Ellen L. Simms

Review author[s]: Joy Bergelson

Altamira and Environs, p. 1632

Iberia Before the Iberians. The Stone Age Prehistory of Cantabrian Spain.

Lawrence Guy Straus

Review author[s]: Randall White

Aeronautical Entrepreneur, pp. 1632-1634

The Universal Man. Theodore von Kármán's Life in Aeronautics.

Michael H. Gorn

Review author[s]: Clayton R. Koppes

Reprints of Books Previously Reviewed, p. 1634

Books Received, p. 1634

Back Matter (30 pp.)

Previous Issue: New Series, Vol. 259, No. 5100, Mar. 5, 1993
Next Issue: New Series, Vol. 259, No. 5102, Mar. 19, 1993

Science, New Series, Vol. 259, No. 5102, Mar. 19, 1993

Previous Issue: New Series, Vol. 259, No. 5101, Mar. 12, 1993
Next Issue: New Series, Vol. 259, No. 5103, Mar. 26, 1993

Front Matter (13 pp.)
Editorial: Expanding the Uses of Enzymes, p. 1675

Philip H. Abelson

Letters

The Oberrothenbach Catastrophe, pp. 1676-1677

Lee W. Wattenberg; Robert N. Proctor

Contamination of cDNA Sequences in Databases, pp. 1677-1678

Charalambos Savakis; Reinhard Doelz

Biotechnology in Japan, p. 1678

Henry I. Miller

Gene Therapy Approval Process, pp. 1678-1679

Ivor Royston

The Cost of Regulation, p. 1679

Thomas D. Hopkins

From the Vatican, p. 1679

G. B. Marini-Bettòlo

ScienceScope, p. 1683

Richard Stone

News and Comment

Genome Shortcut Leads to Problems, pp. 1684-1687

Christopher Anderson

NASA Puts the Squeeze on the Station, p. 1687

Faye Flam

Can Basic Research Ever Find A Good Home in Biosphere 2?, pp. 1688-1689

Traci Watson

Controversial Vaccine Shows Promise, pp. 1689-1690

John Maurice

Swords-to-Plowshares Plan Boosts R&D, p. 1690

Eliot Marshall

Research News

Naked DNA Points Way to Vaccines, pp. 1691-1692

Jon Cohen

Could Quasars Get Their Shine From Stars?, pp. 1692-1693

Ray Jayawardhana

Interfering With Interferon, pp. 1693-1694

Marcia Barinaga

Ecologists Put Some Life Into Models of a Changing World, pp. 1694-1696

Yvonne Baskin

More Venus Science, or The Off Switch for Magellan?, pp. 1696-1697

Richard A. Kerr

Random Samples, pp. 1698-1699

Ivan Amato

Perspectives

The Carved Stela from La Mojarra, Veracruz, Mexico, pp. 1700-1701

George E. Stuart

Does E. coli Have a Nose?, pp. 1701-1702

John S. Parkinson; David F. Blair

A Decipherment of Epi-Olmec Hieroglyphic Writing, pp. 1703-1711

John S. Justeson; Terrence Kaufman

Ancient Conserved Regions in New Gene Sequences and the Protein Databases, pp. 1711-1716

Philip Green; David Lipman; LaDeana Hillier; Robert Waterston; David States; Jean-Michel Claverie

Research Article

Polar Location of the Chemoreceptor Complex in the Escherichia coli Cell, pp. 1717-1723

Janine R. Maddock; Lucille Shapiro

Reports

Formation of Nanometer-Scale Grooves in Silicon with a Scanning Tunneling Microscope, pp. 1724-1726

A. Kobayashi; F. Grey; R. S. Williams; M. Aono

Boundary Layer Profiles in Plasma Chemical Vapor Deposition, pp. 1726-1729

David S. Green; Thomas G. Owano; Skip Williams; David G. Goodwin; Richard N. Zare; Charles H. Kruger

Cryptic Grain-Scale Heterogeneity of Oxygen Isotope Ratios in Metamorphic Magnetite, pp. 1729-1733

John W. Valley; Colin M. Graham

The ¹⁸ O/ ¹⁶ O Ratio of 2-Billion-Year-Old Seawater Inferred from Ancient Oceanic Crust, pp. 1733-1736

C. Holmden; K. Muehlenbachs

Released Form of CNTF Receptor α Component as a Soluble Mediator of CNTF Responses, pp. 1736-1739

Samuel Davis; Thomas H. Aldrich; Nancy Y. Ip; Neil Stahl; Steven Scherer; Thomas Farruggella; Peter S. DiStefano; Rory Curtis; Nikos Panayotatos; Hugues Gascan; Sylvie Chevalier; George D. Yancopoulos

Multiple Defects of Immune Cell Function in Mice with Disrupted Interferon-γ Genes, pp. 1739-1742

Dyana K. Dalton; Sharon Pitts-Meek; Satish Keshav; Irene S. Figari; Allan Bradley; Timothy A. Stewart

Immune Response in Mice That Lack the Interferon-γ Receptor, pp. 1742-1745

Sui Huang; Wiljan Hendriks; Alana Althage; Silvio Hemmi; Horst Bluethmann; Ryutaro Kamijo; Jan Vilček; Rolf M. Zinkernagel; Michel Aguet

Heterologous Protection Against Influenza by Injection of DNA Encoding a Viral Protein, pp. 1745-1749

Jeffrey B. Ulmer; John J. Donnelly; Suezanne E. Parker; Gary H. Rhodes; Philip L. Felgner; V. J. Dwarki; Stanislaw H. Gromkowski; R. Randall Deck; Corrille M. DeWitt; Arthur Friedman; Linda A. Hawe; Karen R. Leander; Douglas Martinez; Helen C. Perry; John W. Shiver; Donna L. Montgomery; Margaret A. Liu

High Levels of HIV-1 in Plasma During All Stages of Infection Determined by Competitive PCR, pp. 1749-1754

M. Piatak, Jr.; M. S. Saag; L. C. Yang; S. J. Clark; J. C. Kappes; K.-C. Luk; B. H. Hahn; G. M. Shaw; J. D. Lifson

Requirement of the Carboxyl Terminus of a Bacterial Chemoreceptor for Its Targeted Proteolysis, pp. 1754-1757

M. R. K. Alley; Janine R. Maddock; Lucille Shapiro

Microbial Competition: Escherichia coli Mutants That Take Over Stationary Phase Cultures, pp. 1757-1760

María Mercedes Zambrano; Deborah A. Siegele; Marta Almirón; Antonio Tormo; Roberto Kolter

An Osmosensing Signal Transduction Pathway in Yeast, pp. 1760-1763

Jay L. Brewster; Tamsen de Valoir; Noelle D. Dwyer; Edward Winter; Michael C. Gustin

PAC-1: A Mitogen-Induced Nuclear Protein Tyrosine Phosphatase, pp. 1763-1766

Patricia J. Rohan; Paula Davis; Christopher A. Moskaluk; Mary Kearns; Henry Krutzsch; Ulrich Siebenlist; Kathleen Kelly

Requirement for Cdk2 in Cytostatic Factor-Mediated Metaphase II Arrest, pp. 1766-1769

Brian G. Gabrielli; Linda M. Roy; James L. Maller

Programmed Cell Death Induced by Ceramide, pp. 1769-1771

Lina M. Obeid; Corinne M. Linardic; Linda A. Karolak; Yusuf A. Hannun

Technical Comments

Ambiguities in Ab Initio Phasing, pp. 1771-1772

Todd O. Yeates; Kam Y. J. Zhang; S. Subbiah

Book Reviews

Instruments of Control, pp. 1773-1774

Testing Testing. Social Consequences of the Examined Life.

F. Allan Hanson

Review author[s]: Robert Jackall

Affinities and Rationales, pp. 1774-1775

The Diversity of Life.

Edward O. Wilson

Review author[s]: Robert E. Ricklefs

Being First, pp. 1775-1776

The Cambridge Guide to Astronomical Discovery.

William Liller

Review author[s]: Ruth C. Peterson

Books Received, p. 1776

Back Matter (20 pp.)

Previous Issue: New Series, Vol. 259, No. 5101, Mar. 12, 1993
Next Issue: New Series, Vol. 259, No. 5103, Mar. 26, 1993

Science, New Series, Vol. 259, No. 5103, Mar. 26, 1993

Previous Issue: New Series, Vol. 259, No. 5102, Mar. 19, 1993
Next Issue: New Series, Vol. 260, No. 5104, Apr. 2, 1993

Volume Information (11 pp.)
Front Matter (47 pp.)
Editorial: The Great Overcoat Scare, p. 1807

Daniel E. Koshland, Jr.

Letters

AIDS Virus History, p. 1809

Jean Claude Gluckman

Japanese Support of U.S. Research, p. 1810

T. S. Benedict Yen

Thoroughly Modern Reptiles, pp. 1810-1811

Royall T. Moore

All in the Family, p. 1811

Peter Mitchell

Kuwait Oil Fires: Correction, pp. 1811-1812

Peter V. Hobbs; Lawrence F. Radke

Corrections and Clarifications: The Global Carbon Dioxide Budget, p. 1812
Corrections and Clarifications: Clinton's Technology Policy Emerges, p. 1812
Corrections and Clarifications: Charting Biodioversity to Guide Conservation, p. 1812

Policy Forum

Integrated Assessment of Climate Change, pp. 1813+1932

Hadi Dowlatabadi; M. Granger Morgan

ScienceScope, p. 1815

Richard Stone

News and Comment

R & D Policy That Emphasizes the `D', pp. 1816-1818+1819

Eliot Marshall

NIST: Measuring Up to a New Task, pp. 1818-1819

Jerome Cramer

NIH Adds an Extra Layer of Review for Sensitive Grants, pp. 1820-1821

Richard Stone

MicroGeneSys Withdraws From Trial, pp. 1821-1822

Jon Cohen

Random Samples, p. 1823

Christopher Anderson

Research News

Plugging a Cosmic Information Leak, pp. 1824-1825

Faye Flam

Aging Twins Offer Clues to Late-Onset Diseases, pp. 1826-1828

David Ansley

Enzyme May Blunt Cocaine's Action, p. 1828

Virginia Morell

The Search for Liver Stem Cells Picks Up, p. 1829

John Travis

Perspective

Protein Prenylation: A Mediator of Protein-Protein Interactions, pp. 1865-1866

Christopher J. Marshall

Dynamics of Elliptical Galaxies, pp. 1867-1871

David Merritt

What Do We Learn from Neutrinos?, pp. 1872-1876

J. Steinberger

Research Article

Regional Ground-Water Mixing and the Origin of Saline Fluids: Midcontinent, United States, pp. 1877-1882

MaryLynn Musgrove; Jay L. Banner

Reports

The Mechanical Response of Gold Substrates Passivated by Self-Assembling Monolayer Films, pp. 1883-1885

Ross C. Thomas; J. E. Houston; Terry A. Michalske; Richard M. Crooks

C ₆₀ H₂: Synthesis of the Simplest C ₆₀ Hydrocarbon Derivative, pp. 1885-1887

Craig C. Henderson; Paul A. Cahill

Fabrication and Properties of Free-Standing C ₆₀ Membranes, pp. 1887-1890

C. B. Eom; A. F. Hebard; L. E. Trimble; G. K. Celler; R. C. Haddon

Outgassed Water on Mars: Constraints from Melt Inclusions in SNC Meteorites, pp. 1890-1892

Harry Y. McSween, Jr.; Ralph P. Harvey

Structural Relationship of Bacterial RecA Proteins to Recombination Proteins from Bacteriophage T4 and Yeast, pp. 1892-1896

Randall M. Story; Douglas K. Bishop; Nancy Kleckner; Thomas A. Steitz

Similarity of the Yeast RAD51 Filament to the Bacterial RecA Filament, pp. 1896-1899

Tomoko Ogawa; Xiong Yu; Akira Shinohara; Edward H. Egelman

Antibody-Catalyzed Degradation of Cocaine, pp. 1899-1901

Donald W. Landry; Kang Zhao; Ginger X.-Q. Yang; Michael Glickman; Taxiarchis M. Georgiadis

Translocation of TCRα Chains into the Lumen of the Endoplasmic Reticulum and Their Degradation, pp. 1901-1904

Jaekyoon Shin; Songjae Lee; Jack L. Strominger

Germ Line Transmission of a Yeast Artificial Chromosome Spanning the Murine _alpha₁ (l) Collagen Locus, pp. 1904-1907

William M. Strauss; Jessica Dausman; Caroline Beard; Carol Johnson; Jeanne B. Lawrence; Rudolf Jaenisch

Cyclin-Dependent Regulation of G₁ in Mammalian Fibroblasts, pp. 1908-1912

Motoaki Ohtsubo; James M. Roberts

NF-κB Controls Expression of Inhibitor IκBα: Evidence for an Inducible Autoregulatory Pathway, pp. 1912-1915

Shao-Cong Sun; Parham A. Ganchi; Dean W. Ballard; Warner C. Greene

Activity-Dependent Regulation of Conductances in Model Neurons, pp. 1915-1917

Gwendal LeMasson; Eve Marder; L. F. Abbott

An Essential Heparin-Binding Domain in the Fibroblast Growth Factor Receptor Kinase, pp. 1918-1921

Mikio Kan; Fen Wang; Jianming Xu; John W. Crabb; Jinzhao Hou; Wallace L. McKeehan

Inside AAAS, p. 1922

Karen Hopkin

Book Reviews

Revelations from Farm Hall, pp. 1923-1926

Heisenberg's War. The Secret History of the German Bomb.

Thomas Powers

Review author[s]: Jeremy Bernstein

The Maya Pantheon, pp. 1926-1927

The Major Gods of Ancient Yucatan.

Karl Andreas Taube

Review author[s]: Jeffrey Kowalski

Language and Prehistory, pp. 1927-1928

Linguistic Diversity in Space and Time.

Johanna Nichols

Review author[s]: William H. Baxter

Mathematical Malaises, pp. 1928-1930

Pi in the Sky. Counting, Thinking, and Being.

John D. Barrow

Review author[s]: Jonathan Borwein; Peter Borwein

Books Received, pp. 1930-1931

Back Matter (49 pp.)

Previous Issue: New Series, Vol. 259, No. 5102, Mar. 19, 1993
Next Issue: New Series, Vol. 260, No. 5104, Apr. 2, 1993

Science, New Series, Vol. 260, No. 5104, Apr. 2, 1993

Previous Issue: New Series, Vol. 259, No. 5103, Mar. 26, 1993
Next Issue: New Series, Vol. 260, No. 5105, Apr. 9, 1993

Front Matter (13 pp.)
Editorial: Improvements in Health Care, p. 11

Philip H. Abelson

Letters

EMF and Cancer, pp. 13-14+16

ORAU Panel on Health Effects of Low-Frequency Electric and Magnetic Fields; Anders Ahlbom; Maria Feychting

Drug Abuse Research, p. 16

Richard A. Millstein

Corrections and Clarifications: Science, Technology, and National Goals, p. 16

Policy Forum

Uncertainty, Resource Exploitation, and Conservation: Lessons from History, pp. 17+36

Donald Ludwig; Ray Hilborn; Carl Waters

ScienceScope, p. 19

Richard Stone

News and Comment

Computing's Controversial Patron, pp. 20-22

Elizabeth Corcoran

American Family Tree Gets New Root, p. 22

Ivan Amato

Researchers Win Decision on Knockout Mouse Pricing, pp. 23-24

Christopher Anderson

NSF Wins, NIH Loses in Clinton's 1994 Budget, pp. 24-25

Christopher Anderson

The Greening of the National Labs, p. 25

Eliot Marshall

Random Samples, pp. 26-27

Traci Watson

Research News

Huntington's Gene Finally Found, pp. 28-30

Virginia Morell

Toxicologists-and Snow-Descend on New Orleans, pp. 30-31

Richard Stone

Ocean-in-a-Machine Starts Looking Like the Real Thing, pp. 32-33

Richard A. Kerr

Pinning Down a Missing Link in Massive Stars, pp. 34-35

Gary Taubes

Perspectives

DNA Repair and Transcription: The Helicase Connection, pp. 37-38

Stephen Buratowski

Superstructures and Superconductivity, pp. 38-39

Zachary Fisk; Gabriel Aeppli

Light Emission from Silicon, pp. 40-46

S. S. Iyer; Y.-H. Xie

Cognitive Neurophysiology of the Motor Cortex, pp. 47-52

Apostolos P. Georgopoulos; Masato Taira; Alexander Lukashin

Research Articles

Molecular Mechanism of Transcription-Repair Coupling, pp. 53-58

Christopher P. Selby; Aziz Sancar

DNA Repair Helicase: A Component of BTF2 (TFIIH) Basic Transcription Factor, pp. 58-63

Laurent Schaeffer; Richard Roy; Sandrine Humbert; Vincent Moncollin; Wim Vermeulen; Jan H. J. Hoeijmakers; Pierre Chambon; Jean-Marc Egly

Reports

Diamonds in Dense Molecular Clouds: A Challenge to the Standard Interstellar Medium Paradigm, pp. 64-66

L. J. Allamandola; S. A. Sandford; A. G. G. M. Tielens; T. M. Herbst

Strong, Pure, and Uniform Carbon Fibers Obtained Directly from the Vapor Phase, pp. 66-68

Frederick T. Wallenberger; Paul C. Nordine

A Photoinduced Persistent Structural Transformation of the Special Pair of a Bacterial Reaction Center, pp. 68-71

N. Raja S. Reddy; Stephen V. Kolaczkowski; Gerald J. Small

Evidence for Photochemical Formation of H₂O₂ and Oxidation of SO₂ in Authentic Fog Water, pp. 71-73

Yuegang Zuo; Jürg Hoigné

Aqueous-Phase Photochemical Formation of Peroxides in Authentic Cloud and Fog Waters, pp. 73-75

Bruce C. Faust; Cort Anastasio; John M. Allen; Takemitsu Arakaki

Genetic Conversion of a Fungal Plant Pathogen to a Nonpathogenic, Endophytic Mutualist, pp. 75-78

Stanley Freeman; Rusty J. Rodriguez

Skn-1a and Skn-1i: Two Functionally Distinct Oct-2-Related Factors Expressed in Epidermis, pp. 78-82

Bogi Andersen; Marcus D. Schonemann; Sarah E. Flynn; Richard V. Pearse; Harinder Singh; Michael G. Rosenfeld

Rhythmic Exocytosis Stimulated by GnRH-Induced Calcium Oscillations in Rat Gonadotropes, pp. 82-84

Amy Tse; Frederick W. Tse; Wolfhard Almers; Bertil Hille

Altered Growth of Human Colon Cancer Cell Lines Disrupted at Activated Ki-ras, pp. 85-88

Senji Shirasawa; Masanori Furuse; Nobuhiko Yokoyama; Takehiko Sasazuki

Phosphatidylinositol 3-Kinase Encoded by Yeast VPS34 Gene Essential for Protein Sorting, pp. 88-91

Peter V. Schu; Kaoru Takegawa; Michael J. Fry; Jeffrey H. Stack; Michael D. Waterfield; Scott D. Emr

Natural Selection and the Origin of jingwei, a Chimeric Processed Functional Gene in Drosophila, pp. 91-95

Manyuan Long; Charles H. Langley

Modulation of Neuronal Migration by NMDA Receptors, pp. 95-97

Hitoshi Komuro; Pasko Rakic

HLA-A11 Epitope Loss Isolates of Epstein-Barr Virus from a Highly A11⁺ Population, pp. 98-100

Pedro-Otavio de Campos-Lima; Riccardo Gavioli; Qian-Jin Zhang; Lesley E. Wallace; Riccardo Dolcetti; Martin Rowe; Alan B. Rickinson; Maria G. Masucci

Extracellular Access to the Na,K Pump: Pathway Similar to Ion Channel, pp. 100-103

David C. Gadsby; R. F. Rakowski; Paul De Weer

Developmental Regulation of Neural Response to FGF-1 and FGF-2 by Heparan Sulfate Proteoglycan, pp. 103-106

Victor Nurcombe; Miriam D. Ford; Jason A. Wildschut; Perry F. Bartlett

Book Reviews

Progress in the Infrared, p. 107

Infrared Astronomy with ISO.

Th. Encrenaz; M. F. Kessler

Review author[s]: Charles A. Beichman

Future-Oriented Physics, pp. 107-109

Dynamics of the Standard Model.

John F. Donoghue; Eugene Golowich; Barry R. Holstein

Review author[s]: Persis S. Drell

Life of an Evolutionist, pp. 109-110

William Diller Matthew, Paleontologist. The Splendid Drama Observed.

Edwin H. Colbert

Review author[s]: Léo F. Laporte

Books Received, p. 110

Back Matter (22 pp.)

Previous Issue: New Series, Vol. 259, No. 5103, Mar. 26, 1993
Next Issue: New Series, Vol. 260, No. 5105, Apr. 9, 1993

Science, New Series, Vol. 260, No. 5105, Apr. 9, 1993

Previous Issue: New Series, Vol. 260, No. 5104, Apr. 2, 1993
Next Issue: New Series, Vol. 260, No. 5106, Apr. 16, 1993

Front Matter (15 pp.)
Editorial: Science and Society, p. 143

Daniel E. Koshland, Jr.

Letters

Audit at Woods Hole, p. 145

Craig E. Dorman

Drugs from Third World Plants: Creative Approaches, p. 145

Irving S. Johnson

No Lack of NO Activity, pp. 145-146

Francis T. Bonner; Martin N. Hughes; Thomas Michel

Tyrolean Paraphernalia, pp. 146-147

Michael L. Grant; Robert Temple; Norris Denman; Kathryn A. Klar

Sociological Discourse, p. 147

Jan A. Witkowski

ScienceScope, p. 151

Richard Stone

News and Comment

Genome Project Plans Described, pp. 152-153

Jean Marx

Clinton Asks for a Greener DOE, p. 153

Christopher Anderson

Suprise! A Fungus Factory For Taxol?, pp. 154-155

Richard Stone

At Tokyo University, a Parting Shot, p. 155

Fred Myers

The Cost of Scientific Pork Keeps Going Up, p. 156

Eliot Marshall

Early AZT Takes a Pounding in French-British 'Concorde' Trial, p. 157

Jon Cohen

Random Samples, p. 158

Constance Holden

Research News

Ulcers as an Infectious Disease, pp. 159-160

Joseph Alper

Why Some Fishes are Hotheads, pp. 160-161

Traci Watson

Biologists Visit New Orleans (Under an Assumed Name), pp. 162-163

John Travis

A New Supernova In the Northern Sky, p. 163

Ray Jayawardhana

Tribe of Brown Dwarfs Discovered?, pp. 163-164

Peter Aldhous

Condensed Matter Physicists Shrink Their Horizons, pp. 164-165

Faye Flam

Perspectives

Forging an Asteroid-Meteorite Link, pp. 167-168

Michael J. Gaffey

Measuring Single Protein Motors at Work, pp. 169-170

Ronald D. Vale

Near-Field Investigations of the Landers Earthquake Sequence, April to July 1992, pp. 171-176

Kerry Sieh; Lucile Jones; Egill Hauksson; Kenneth Hudnut; Donna Eberhart-Phillips; Thomas Heaton; Susan Hough; Kate Hutton; Hiroo Kanamori; Anne Lilje; Scott Lindvall; Sally F. McGill; James Mori; Charles Rubin; James A. Spotila; Joann Stock; Hong Kie Thio; Jerome Treiman; Brian Wernicke; Judith Zachariasen

A Nickel Metal Hydride Battery for Electric Vehicles, pp. 176-181

S. R. Ovshinsky; M. A. Fetcenko; J. Ross

Research Articles

Regulation of Gene Expression in Hippocampal Neurons by Distinct Calcium Signaling Pathways, pp. 181-186

Hilmar Bading; David D. Ginty; Michael E. Greenberg

Chips off of Asteroid 4 Vesta: Evidence for the Parent Body of Basaltic Achondrite Meteorites, pp. 186-191

Richard P. Binzel; Shui Xu

Reports

Silica Precipitation in Fractures and the Evolution of Permeability in Hydrothermal Upflow Zones, pp. 192-194

Robert P. Lowell; Philippe Van Cappellen; Leonid N. Germanovich

Production of Metallo-Carbohedrenes in the Solid State, pp. 195-196

S. F. Cartier; Z. Y. Chen; G. J. Walder; C. R. Sleppy; A. W. Castleman, Jr.

Metastability of Superconducting Compounds in the Y-Ba-Cu-O System, pp. 196-198

Eric L. Brosha; Peter K. Davies; Fernando H. Garzon; Ian D. Raistrick

Electrostatic Screening of Charge and Dipole Interactions with the Helix Backbone, pp. 198-202

David J. Lockhart; Peter S. Kim

Pressure-Induced Amorphization of R-Al₅Li₃Cu: A Structural Relation Among Amorphous Metals, Quasi-Crystals, and Curved Space, pp. 202-204

Robert R. Winters; William S. Hammack

Velocity Structure of a Gas Hydrate Reflector, pp. 204-207

Satish C. Singh; Timothy A. Minshull; George D. Spence

Impairment of V(D)J Recombination in Double-Strand Break Repair Mutants, pp. 207-210

Guillermo E. Taccioli; Gary Rathbun; Eugene Oltz; Thomas Stamato; Penny A. Jeggo; Frederick W. Alt

Evolution of Endothermy in Fish: Mapping Physiological Traits on a Molecular Phylogeny, pp. 210-214

Barbara A. Block; John R. Finnerty; Alexandre F. R. Stewart; Jessica Kidd

Taxol and Taxane Production by Taxomyces andreanae, an Endophytic Fungus of Pacific Yew, pp. 214-216

Andrea Stierle; Gary Strobel; Donald Stierle

Frequency-Dependent Natural Selection in the Handedness of Scale-Eating Cichlid Fish, pp. 216-219

Michio Hori

Distinct Functions of SR Proteins in Alternative Pre-mRNA Splicing, pp. 219-222

Alan M. Zahler; Karla M. Neugebauer; William S. Lane; Mark B. Roth

Spatially Resolved Dynamics of cAMP and Protein Kinase A Subunits in Aplysia Sensory Neurons, pp. 222-226

Brian J. Bacskai; Binyamin Hochner; Martyn Mahaut-Smith; Stephen R. Adams; Bong-Kiun Kaang; Eric R. Kandel; Roger Y. Tsien

Increased Frequency of Calcium Waves in Xenopus laevis Oocytes That Express a Calcium-ATPase, pp. 226-229

Patricia Camacho; James D. Lechleiter

Acceleration of Intracellular Calcium Waves in Xenopus Oocytes by Calcium Influx, pp. 229-232

Steven Girard; David Clapham

Force of Single Kinesin Molecules Measured With Optical Tweezers, pp. 232-234

Scot C. Kuo; Michael P. Sheetz

Decreased Expression of Myotonin-Protein Kinase Messenger RNA and Protein in Adult Form of Myotonic Dystrophy, pp. 235-238

Ying-Hui Fu; David L. Friedman; Stephen Richards; Joel A. Pearlman; Richard A. Gibbs; Antonio Pizzuti; Tetsuo Ashizawa; M. Benjamin Perryman; Guglielmo Scarlato; Raymond G. Fenwick, Jr.; C. Thomas Caskey

Regulation of CREB Phosphorylation in the Suprachiasmatic Nucleus by Light and a Circadian Clock, pp. 238-241

David D. Ginty; Jon M. Kornhauser; Margaret A. Thompson; Hilmar Bading; Kelly E. Mayo; Joseph S. Takahashi; Michael E. Greenberg

Technical Comments

Effect of Scale on Food Web Structure, pp. 242-243

Neo D. Martinez; Karl Havens

Book Reviews

Neural Integration, p. 244

Dynamic Biological Networks. The Stomatogastric Nervous System.

Ronald M. Harris-Warrick; Eve Marder; Allen I. Selverston; Maurice Moulins

Review author[s]: Christine L. Sahley

Land-Based Evolution, pp. 244-245

Terrestrial Ecosystems Through Time. Evolutionary Paleoecology of Terrestrial Plants and Animals.

Anna K. Behrensmeyer; John D. Damuth; William A. DiMichele; Richard Potts; Hans-Dieter Sues; Scott L. Wing

Review author[s]: James W. Valentine

A Backwater Reconsidered, pp. 245-247

Wealth and Hierarchy in the Intermediate Area.

Frederick W. Lange

Review author[s]: Winifred Creamer

Books Received, p. 247

Back Matter (17 pp.)

Previous Issue: New Series, Vol. 260, No. 5104, Apr. 2, 1993
Next Issue: New Series, Vol. 260, No. 5106, Apr. 16, 1993

Science, New Series, Vol. 260, No. 5106, Apr. 16, 1993

Previous Issue: New Series, Vol. 260, No. 5105, Apr. 9, 1993
Next Issue: New Series, Vol. 260, No. 5107, Apr. 23, 1993

Front Matter (49 pp.)
Editorial: Women in Science, p. 275

Daniel E. Koshland, Jr.

Letters

Japan's SAT?, pp. 277-278

Kevin R. Gregg; Norman McLeod; John J. Carroll; Suck Won Kim

Nuclear Structure Research, p. 278

Jeanne B. Lawrence

Determining Paleoclimates, pp. 278-279

David R. Greenwood; Scott L. Wing; Anna K. Behrensmeyer

Fish Otolith Chemistry, p. 279

John M. Kalish

Plasma Wave Accelerators, p. 280

Robert N. Cahn

Correction: Omitted Author: Requirement for CD8⁺ Cells in T cell Receptor Peptide-Induced Clonal Unresponsiveness, p. 280
Corrections and Clarifications: Death Gives Birth to the Nervous System. But How?, p. 280
Corrections and Clarifications: Light Emission from Silicon, p. 280

Policy Forum

What Does Utility-Subsidized Energy Efficiency Really Cost?, pp. 281+370

Paul L. Joskow; Donald B. Marron

ScienceScope, p. 283

Richard Stone

News

Clinton's Mixed Broth for R&D, pp. 284-285

Eliot Marshall; Christopher Anderson

NASA Launches a 5-Year Plan to Clone Drones, p. 286

Gary Taubes

Blue Whale Population May be Increasing Off California, p. 287

Yvonne Baskin

MicroGeneSys: NIH Faces Down DOD, p. 288

Jon Cohen

NIH Fraudbusters Get Busted, p. 288

Christopher Anderson

Volcanologists Ponder a Spate of Deaths in the Line of Duty, pp. 289-290

Richard A. Kerr

Researchers Defy the Physical Limits to Computation, pp. 290-291

Faye Flam

Keystone's Blunt Message: 'It's the Virus, Stupid', pp. 292-293

Jon Cohen

Chemists Gather in Denver to Get the Big Picture, pp. 293-294

Ivan Amato

Random Samples, p. 295

Constance Holden

Perspective

Methylation and Imprinting: From Host Defense to Gene Regulation?, pp. 309-310

Denise P. Barlow

The Relative Roles of Sulfate Aerosols and Greenhouse Gases in Climate Forcing, pp. 311-314

J. T. Kiehl; B. P. Briegleb

Research Article

A Divergence in the MAP Kinase Regulatory Network Defined by MEK Kinase and Raf, pp. 315-319

Carol A. Lange-Carter; Chris M. Pleiman; Anne M. Gardner; Kendall J. Blumer; Gary L. Johnson

Reports

Bipolar Spin Switch, pp. 320-323

Mark Johnson

Structure of Langmuir-Blodgett Films of Disk-Shaped Molecules Determined by Atomic Force Microscopy, pp. 323-326

Jack Y. Josefowicz; Nicholas C. Maliszewskyj; Stefan H. J. Idziak; Paul A. Heiney; John P. McCauley, Jr.; Amos B. Smith III

The Drift of Saturn's North Polar Spot Observed by the Hubble Space Telescope, pp. 326-329

John Caldwell; Xin-Min Hua; Benoit Turgeon; James A. Westphal; Christopher D. Barnet

Ground-Based Observations of Saturn's North Polar Spot and Hexagon, pp. 329-332

A. Sanchez-Lavega; J. Lecacheux; F. Colas; P. Laques

In-Plane Structure of the Liquid-Vapor Interface of an Alloy: A Grazing Incidence X-ray Diffraction Study of Bismuth:Gallium, pp. 332-335

Erik B. Flom; Mengyang Li; Anibal Acero; Nissan Maskil; Stuart A. Rice

Pattern Recognition in Coupled Chemical Kinetic Systems, pp. 335-337

A. Hjelmfelt; F. W. Schneider; J. Ross

Controlling Chemical Reactivity with Antibodies, pp. 337-339

Linda C. Hsieh; Shirlee Yonkovich; Lynn Kochersperger; Peter G. Schultz

Monophyletic Origins of the Metazoa: An Evolutionary Link with Fungi, pp. 340-342

Patricia O. Wainright; Gregory Hinkle; Mitchell L. Sogin; Shawn K. Stickel

Identification of a Mobile Endogenous Transposon in Arabidopsis thaliana, pp. 342-344

Yi-Fang Tsay; Mary J. Frank; Tania Page; Caroline Dean; Nigel M. Crawford

Soil Quality and Financial Performance of Biodynamic and Conventional Farms in New Zealand, pp. 344-349

John P. Reganold; Alan S. Palmer; James C. Lockhart; A. Neil Macgregor

Transient Transfection and Expression in the Obligate Intracellular Parasite Toxoplasma gondii, pp. 349-352

Dominique Soldati; John C. Boothroyd

Structure of DNA Polymerase I Klenow Fragment Bound to Duplex DNA, pp. 352-355

Lorena S. Beese; Victoria Derbyshire; Thomas A. Steitz

Preferential Migration of Activated CD4⁺ and CD8⁺ T Cells in Response to MIP-1a and MIP-1b, pp. 355-358

Dennis D. Taub; Kevin Conlon; Andrew R. Lloyd; Joost J. Oppenheim; David J. Kelvin

Requirement for Tyrosine Kinase p56 ^lck for Thymic Development of Transgenic gd T Cells, pp. 358-361

Josef Penninger; Kenji Kishihara; Thierry Molina; Valerie A. Wallace; Emma Timms; Stephen M. Hedrick; Tak W. Mak

Tumor Cell Growth Arrest Caused by Subchromosomal Transferable DNA Fragments from Chromosome 11, pp. 361-364

Minoru Koi; Laura A. Johnson; Linda M. Kalikin; Peter F. R. Little; Yusuke Nakamura; Andrew P. Feinberg

Import of a Mitochondrial Presequence into Protein-Free Phospholipid Vesicles, pp. 364-367

Merritt Maduke; David Roise

Neuronal Differentiation Rescued by Implantation of Weaver Granule Cell Precursors into Wild-Type Cerebellar Cortex, pp. 367-369

Wei-Qiang Gao; Mary E. Hatten

Book Reviews

Ménages à Plusieurs, pp. 374-375

Dunnock Behaviour and Social Evolution.

N. B. Davies

Review author[s]: Robert Gibson

The Seventh Continent, pp. 375-376

The Geology of Antarctica.

Robert J. Tingey

Review author[s]: Scott Borg

Maya Paleodemography, p. 376

Precolumbian Population History in the Maya Lowlands.

T. Patrick Culbert; Don S. Rice

Review author[s]: Nicholas P. Dunning

A Young Collector, pp. 376-377

The Dragon in the Cliff. A Novel Based on the Life of Mary Anning.

Sheila Cole; T. D. Farrow

Review author[s]: Anna K. Behrensmeyer

Women in Science: Bibliographic Update, p. 377

Book Reviews

Books Received, p. 378

Women in Science: Gender and the Culture of Science

The Female Style

Is There a `Female Style' in Science?, pp. 384-385+386+390-391

Marcia Barinaga

No More Stressed-Out Supermom, p. 385

Ann Gibbons

The Male Box: Male Researchers Respond, p. 387

Robert M. Gray

Writing a New Script for Science, p. 391

Toomas Koppel

Feminists Find Gender Everywhere In Science, pp. 392-393

Marcia Barinaga

Gaining Standing-by Standing Out, p. 393

Ann Gibbons

Industrial R&D

Women Struggle to Crack the Code of Corporate Culture, pp. 398-399+400-402+404

Elizabeth Culotta

Traveling Without Maps, p. 399

Ann Gibbons

Our Thinking Is Difficult to Change, p. 402

Toomas Koppel

Scandinavian Fairy Tale, p. 404

Patricia Kahn

Entrepreneurs Say: `It's Better to Be the Boss', p. 406

E. C.

Science Education

The Pipeline Is Leaking Women All the Way Along, pp. 409-411

Joe Alper

A Thoroughly Modern Marriage, p. 411

Ann Gibbons

Making Room for Women in the Culture of Science, pp. 412-415

John Travis

A Case Study: Primatology

Called `Trimates,' Three Bold Women Shaped Their Field, pp. 420-421+422-423+424-425

Virginia Morell

Lone Star State, p. 421

Patricia Kahn

No Girls Need Apply, p. 422

Toomas Koppel

A Prize of One's Own, p. 424

Dennis Normile

Seeing Nature Through the Lens of Gender, pp. 428-429

V. M.

Women in Science '93: Additional Readings, p. 430

Back Matter (30 pp.)

Previous Issue: New Series, Vol. 260, No. 5105, Apr. 9, 1993
Next Issue: New Series, Vol. 260, No. 5107, Apr. 23, 1993

Science, New Series, Vol. 260, No. 5107, Apr. 23, 1993

Previous Issue: New Series, Vol. 260, No. 5106, Apr. 16, 1993
Next Issue: New Series, Vol. 260, No. 5108, Apr. 30, 1993

Front Matter (22 pp.)
Editorial: Science and Technology in Government, p. 471

Richard S. Nicholson; Philip H. Abelson

Letters

DNA Fingerprinting Report, pp. 473-474

B. S. Weir; Daniel L. Hartl; Richard C. Lewontin

Extraterrestrial Intelligence, pp. 474-475

Frank Drake; John D. Rummel; David M. Raup

ScienceScope, p. 479

Richard Stone

News and Comment

A Clouded Future for IBM Research, pp. 480-481

David H. Freedman

Drug Companies Join Forces In Search for AIDS Therapy, p. 482

Jon Cohen

A New Kind of Earmarking, p. 483

Christopher Anderson

Mirror, Mirror, Which Is the Fairest?, pp. 483-484

Faye Flam

At State Schools, Calculus Reform Goes Mainstream, pp. 484-485

Barry Cipra

AAAS's Very Own Red Scare, p. 486

Wayne Biddle

PCR Enzyme Patent Challenged, p. 486

Peter Aldhous

Research News

Secrets of Secretion Revealed, pp. 487-489

Marcia Barinaga

Ozone Takes a Nose Dive After The Eruption of Mt. Pinatubo, pp. 490-491

Richard A. Kerr

How to Drive Nucleic Acids Up a Tree, p. 491

Ivan Amato

OGLEing, MACHOs, and the Search for Dark Matter, pp. 492-493

Gary Taubes

Scientists Chase Gravity's Rainbow, p. 493

Faye Flam

Random Samples, pp. 494-495

Constance Holden

Perspective

IL-12: Initiation Cytokine for Cell-Mediated Immunity, pp. 496-497

Phillip Scott

Removal of Contaminants from Soils by Electric Fields, pp. 498-503

Ronald F. Probstein; R. Edwin Hicks

Research Article

Movement of the Guide Sequence During RNA Catalysis by a Group I Ribozyme, pp. 504-508

Jin-Feng Wang; William D. Downs; Thomas R. Cech

Reports

The Opposition Effect of the Moon: The Contribution of Coherent Backscatter, pp. 509-511

Bruce W. Hapke; Robert M. Nelson; William D. Smythe

Manganese Oxide Octahedral Molecular Sieves: Preparation, Characterization, and Applications, pp. 511-515

Y. F. Shen; R. P. Zerger; R. N. DeGuzman; S. L. Suib; L. McCurdy; D. I. Potter; C. L. O'Young

Vapor-Condensation Generation and STM Analysis of Fullerene Tubes, pp. 515-518

Maohui Ge; Klaus Sattler

Oxygen Diffusion in Perovskite: Implications for Electrical Conductivity in the Lower Mantle, pp. 518-521

Bjarni Gautason; Karlis Muehlenbachs

The Relation Between Biological Activity of the Rain Forest and Mineral Composition of Soils, pp. 521-523

Y. Lucas; F. J. Luizão; A. Chauvel; J. Rouiller; D. Nahon

Record Low Global Ozone in 1992, pp. 523-526

J. F. Gleason; P. K. Bhartia; J. R. Herman; R. McPeters; P. Newman; R. S. Stolarski; L. Flynn; G. Labow; D. Larko; C. Seftor; C. Wellemeyer; W. D. Komhyr; A. J. Miller; W. Planet

Tectonics and Volcanism of Eastern Aphrodite Terra, Venus: No Subduction, No Spreading, pp. 526-530

Vicki L. Hansen; Roger J. Phillips

Molecular Basis for Specific Recognition of Both RNA and DNA by a Zinc Finger Protein, pp. 530-533

Karen R. Clemens; Veronica Wolf; Steven J. McBryant; Penghua Zhang; Xiubei Liao; Peter E. Wright; Joel M. Gottesfeld

Knotting of a DNA Chain During Ring Closure, pp. 533-536

Stanley Y. Shaw; James C. Wang

Negative Regulation of G1 in Mammalian Cells: Inhibition of Cyclin E-Dependent Kinase by TGF-β, pp. 536-539

Andrew Koff; Masahiko Ohtsuki; Kornelia Polyak; James M. Roberts; Joan Massagué

Reversible Binding of Nitric Oxide by a Salivary Heme Protein from a Bloodsucking Insect, pp. 539-541

José M. C. Ribeiro; Jo M. H. Hazzard; Roberto H. Nussenzveig; Donald E. Champagne; F. Ann Walker

Regulation of TCR Signaling by CD45 Lacking Transmembrane and Extracellular Domains, pp. 541-544

Siniša Volarević; Barbara B. Niklinska; Christopher M. Burns; Carl H. June; Allan M. Weissman; Jonathan D. Ashwell

Rescue of Signaling by a Chimeric Protein Containing the Cytoplasmic Domain of CD45, pp. 544-546

Robin R. Hovis; Jerald A. Donovan; Michael A. Musci; David G. Motto; Frederick D. Goldman; Susan E. Ross; Gary A. Koretzky

Development of T_H1 CD4⁺ T Cells Through IL-12 Produced by Listeria-Induced Macrophages, pp. 547-549

Chyi-Song Hsieh; Steven E. Macatonia; Catherine S. Tripp; Stanley F. Wolf; Anne O'Garra; Kenneth M. Murphy

Technical Comments

Delivery of Na⁺, K⁺-ATPase in Polarized Epithelial Cells, pp. 550-556

Chiara Zurzolo; Enrique Rodriguez-Boulan; Cara J. Gottardi; Michael J. Caplan; Kathleen A. Siemers (Krzeminski); Rachel Wilson (Hammerton); Robert W. Mays; Timothy A. Ryan; Debra A. Wollner; W. James Nelson

Book Reviews

Sea-Level Fluctuations, p. 565

Phanerozoic Sea-Level Changes.

Anthony Hallam

Review author[s]: Edward Winterer

Single-Cell Fossils, pp. 565-566

Fossil Prokaryotes and Protists.

Jere H. Lipps

Review author[s]: Kenneth H. Nealson

Managing Motion, pp. 567-568

Vestibular and Brain Stem Control of Eye, Head and Body Movements.

Hiroshi Shimazu; Yoshikazu Shinoda

Sensing and Controlling Motion. Vestibular and Sensorimotor Function.

Bernard Cohen; David L. Tomko; Fred Guedry

Review author[s]: R. David Tomlinson

New Haven Observers, pp. 568-569

Astronomy at Yale, 1701-1968.

Dorrit Hoffleit

Review author[s]: Donald E. Osterbrock

The Construction of Stars, pp. 569-570

Structure and Evolution of Single and Binary Stars.

C. W. H. De Loore; C. Doom

Review author[s]: Scott J. Kenyon

Books Received, pp. 570-573

Back Matter (19 pp.)

Previous Issue: New Series, Vol. 260, No. 5106, Apr. 16, 1993
Next Issue: New Series, Vol. 260, No. 5108, Apr. 30, 1993

Science, New Series, Vol. 260, No. 5108, Apr. 30, 1993

Previous Issue: New Series, Vol. 260, No. 5107, Apr. 23, 1993
Next Issue: New Series, Vol. 260, No. 5109, May 7, 1993

Front Matter (13 pp.)
Editorial: Moderation in Science Budgeting, p. 603

Daniel E. Koshland, Jr.

Letters

Database Contamination, pp. 605-606

Vivian H. Gersuk; Timothy M. Rose; Richard H. Kessin; Michiel M. Van Lookeren Campagne; Anita Mistry; Robert Greenlee; Kenneth Fong

Sequencing the Human Genome, pp. 606-607

Randy W. Scott

Converting Weapons to Fuel, p. 607

Stanley G. Prussin; C. Roger Glassey; G. Melese

The G-Word, pp. 607-608

Dick Teresi

Incorrect GenBank Numbers, p. 608

Morris Goodman

ScienceScope, p. 611

Richard Stone

News and Comment

LIGO: A $250 Million Gamble, pp. 612-614

John Travis

NSF's Hopes Filibustered, p. 615

Eliot Marshall

Sex Surveys Come Out of the Closet, pp. 615-616

Traci Watson

Clinton's Science and Technology Team Takes Shape, pp. 616-617

Christopher Anderson

Random Samples, pp. 618-619

Constance Holden

Research News

Counting Creatures Great and Small, pp. 620-622

Carol Kaesuk Yoon

Practicing the Poor Man's Brand of Particle Physics, pp. 622-623

Faye Flam

Genetic 'Master Switch' for Left-Right Symmetry Found, pp. 624-625

Tania Ewing

Quasars: Double Darkness in Draco, p. 625

Ray Jayawardhana

Perspective

Cytokines and Estrogen in Bone: Anti-Osteoporotic Effects, pp. 626-627

Mark C. Horowitz

Nile Delta: Recent Geological Evolution and Human Impact, pp. 628-634

Daniel Jean Stanley; Andrew G. Warne

Computer-Simulation Methods in the Study of Noncrystalline Materials, pp. 635-640

Fumiko Yonezawa

Research Articles

Microfossils of the Early Archean Apex Chert: New Evidence of the Antiquity of Life, pp. 640-646

J. William Schopf

Reports

Imaging of Features on Surfaces by Condensation Figures, pp. 647-649

Gabriel P. López; Hans A. Biebuyck; C. Daniel Frisbie; George M. Whitesides

Condensed-Matter Energetics from Diatomic Molecular Spectra, pp. 649-652

In Ho Kim; Raymond Jeanloz; Kyu Soo Jhung

Rates of Electron Emission from Negatively Charged, Impact-Heated Fullerenes, pp. 652-656

Chahan Yeretzian; Klavs Hansen; Robert L. Whetten

Van der Waals Epitaxial Growth of α-Alumina Nanocrystals on Mica, pp. 656-659

S. Steinberg; W. Ducker; G. Vigil; C. Hyukjin; C. Frank; M. Z. Tseng; D. R. Clarke; J. N. Israelachvili

Preparation of Amorphous Boron Nitride and Its Conversion to a Turbostratic, Tubular Form, pp. 659-661

Ewan J. M. Hamilton; Shawn E. Dolan; Charles M. Mann; Hendrik O. Colijn; Clare A. McDonald; Sheldon G. Shore

Banded Surface Flow Maintained by Convection in a Model of the Rapidly Rotating Giant Planets, pp. 661-664

Zi-Ping Sun; Gerald Schubert; Gary A. Glatzmaier

Water Sources for Subduction Zone Volcanism: New Experimental Constraints, pp. 664-667

Alison R. Pawley; John R. Holloway

Pliocene Paleoclimate and East Antarctic Ice-Sheet History from Surficial Ash Deposits, pp. 667-670

David R. Marchant; Carl C. Swisher; Daniel R. Lux; David P. West, Jr.; George H. Denton

Social Structure of Pilot Whales Revealed by Analytical DNA Profiling, pp. 670-672

Bill Amos; Christian Schlötterer; Diethard Tautz

A Laccase Associated with Lignification in Loblolly Pine Xylem, pp. 672-674

Wuli Bao; David M. O'Malley; Ross Whetten; Ronald R. Sederoff

Where Plants Make Oxygen: A Structural Model for the Photosynthetic Oxygen-Evolving Manganese Cluster, pp. 675-679

Vittal K. Yachandra; Victoria J. DeRose; Matthew J. Latimer; Ishita Mukerji; Kenneth Sauer; Melvin P. Klein

Reversal of Left-Right Asymmetry: A Situs Inversus Mutation, pp. 679-682

Takahiko Yokoyama; Neal G. Copeland; Nancy A. Jenkins; Charles A. Montgomery; Frederick F. B. Elder; Paul A. Overbeek

Cytoskeletal Role in the Contractile Dysfunction of Hypertrophied Myocardium, pp. 682-687

Hiroyuki Tsutsui; Kazuaki Ishihara; George Cooper

Intermediate Filament Formation by a Yeast Protein Essential for Organelle Inheritance, pp. 687-689

Stephen J. McConnell; Michael P. Yaffe

Rapid Loss of CD4⁺ T Cells in Human-PBL-SCID Mice by Noncytopathic HIV Isolates, pp. 689-692

Donald E. Mosier; Richard J. Gulizia; Paul D. MacIsaac; Bruce E. Torbett; Jay A. Levy

Retinoic Acid Stimulates Regeneration of Mammalian Auditory Hair Cells, pp. 692-695

Philippe P. Lefebvre; Brigitte Malgrange; Hinrich Staecker; Gustave Moonen; Thomas R. Van De Water

Linkage on Chromosome 3 of Autoimmune Diabetes and Defective Fc Receptor for IgG in NOD Mice, pp. 695-698

Jan-Bas Prins; John A. Todd; Nanda R. Rodrigues; Soumitra Ghosh; P. Mark Hogarth; Linda S. Wicker; Erin Gaffney; Patricia L. Podolin; Paul A. Fischer; Anna Sirotina; Laurence B. Peterson

Technical Comments

Immuno-PCR with a Commercially Available Avidin System, pp. 698-699

Viktor Ruzicka; Winfried März; Andreas Russ; Werner Gross; Takeshi Sano; Cassandra L. Smith; Charles R. Cantor

Inside AAAS, pp. 700-702

Karen Hopkin

Book Reviews

Research via Rocket, pp. 703-704

Science with a Vengeance. How the Military Created the US Space Sciences After World War II.

David H. DeVorkin

Review author[s]: Alex Roland

Routes to Agriculture, pp. 704-705

The Origins of Agriculture and Settled Life.

Richard S. MacNeish

Review author[s]: Patty Jo Watson

Plasma Astrophysics, p. 705

Extragalactic Radio Sources. From Beams to Jets.

J. Roland; H. Sol; G. Pelletier

Review author[s]: Mitchell C. Begelman

Adaptive Abilities, pp. 705-706

Insect Learning. Ecological and Evolutionary Perspectives.

Daniel R. Papaj; Alcinda C. Lewis

Review author[s]: Bernd Heinrich

Books Received, p. 706

Back Matter (18 pp.)

Previous Issue: New Series, Vol. 260, No. 5107, Apr. 23, 1993
Next Issue: New Series, Vol. 260, No. 5109, May 7, 1993

Science, New Series, Vol. 260, No. 5109, May 7, 1993

Previous Issue: New Series, Vol. 260, No. 5108, Apr. 30, 1993
Next Issue: New Series, Vol. 260, No. 5110, May 14, 1993

Front Matter (26 pp.)
Editorial: Policies for Science and Technology, p. 735

Philip H. Abelson

Letters

Support for the SSC, pp. 737-738

G. H. Trilling

DOE, Taiwan, and SSC Support, p. 738

T. D. Lee

Carbon Monoxide and Dilation of Blood Vessels, p. 739

Flavio Coceani

UCSF Research Institute: No Hughes Approval, pp. 739-740

Lewis T. Williams

Recoverin's Role: Conclusion Withdrawn, p. 740

James B. Hurley; Alexander M. Dizhoor; Sanghanitra Ray; Lubert Stryer

Corrections and Clarifications: Clinton Asks for a Greener DOE, p. 740
ScienceScope, p. 743

Richard Stone

News and Comment

Big Science Enters the Clinic, pp. 744-745+746-747

Eliot Marshall

Affirmative Action for Clinical Trials, p. 746

Traci Watson

Proposal to Counter Scientist `Shortage' Draws Fire, p. 748

Christopher Anderson

Dispute Over Exxon Valdez Cleanup Data Gets Messy, p. 749

Richard Stone

New Test Catches Drug-Resistant TB in the Spotlight, p. 750

Marcia Barinaga

Research News

New Colon Cancer Gene Discovered, pp. 751-752

Jean Marx

Designer Solids: Haute Couture in Chemistry, pp. 753-755

Ivan Amato

Finally, a Hotter Superconductor, pp. 755-756

Ivan Amato

A Double Dose of Gamma-Ray Bursts, p. 756

Faye Flam

Random Samples, p. 757

Constance Holden

Perspectives

The Many Roads That Lead to Ras, pp. 767-768

Larry A. Feig

Late Triassic Extinctions and the Origin of the Dinosaurs, pp. 769-770

Michael J. Benton

Rheology of the Upper Mantle: A Synthesis, pp. 771-778

Shun-ichiro Karato; Patrick Wu

Research Article

Structure-Specific Endonucleolytic Cleavage of Nucleic Acids by Eubacterial DNA Polymerases, pp. 778-783

Victor Lyamichev; Mary Ann D. Brow; James E. Dahlberg

Reports

Annealing C ₆₀ ⁺: Synthesis of Fullerenes and Large Carbon Rings, pp. 784-786

Joanna Hunter; James Fye; Martin F. Jarrold

A Photomicrodynamic System with a Mechanical Resonator Monolithically Integrated with Laser Diodes on Gallium Arsenide, pp. 786-789

Hiroo Ukita; Yuji Uenishi; Hidenao Tanaka

X-ray Tomographic Study of Chemical Vapor Infiltration Processing of Ceramic Composites, pp. 789-792

J. H. Kinney; T. M. Breunig; T. L. Starr; D. Haupt; M. C. Nichols; S. R. Stock; M. D. Butts; R. A. Saroyan

The Nitrogenase FeMo-Cofactor and P-Cluster Pair: 2.2 $\overset{\circ}{\mathrm A}$ Resolution Structures, pp. 792-794

Michael K. Chan; Jongsun Kim; D. C. Rees

The Ischigualasto Tetrapod Assemblage (Late Triassic, Argentina) and ⁴⁰ Ar/ ³⁹ Ar Dating of Dinosaur Origins, pp. 794-797

Raymond R. Rogers; Carl C. Swisher III; Paul C. Sereno; Alfredo M. Monetta; Catherine A. Forster; Ricardo N. Martínez

Copernicus: A Regional Probe of the Lunar Interior, pp. 797-801

Patrick C. Pinet; Serge D. Chevrel; Patrick Martin

Sequences and Structures Required for Recombination Between Virus-Associated RNAs, pp. 801-805

Pamela J. Cascone; Tarik F. Haydar; Anne E. Simon

Protein-Induced Bending as a Transcriptional Switch, pp. 805-807

José Pérez-Martín; Manuel Espinosa

Ryanodine Receptor Adaptation: Control Mechanism of Ca ²⁺ -Induced Ca ²⁺ Release in Heart, pp. 807-809

Sandor Györke; Michael Fill

Genetic Mapping of a Locus Predisposing to Human Colorectal Cancer, pp. 810-812

Päivi Peltomäki; Lauri A. Aaltonen; Pertti Sistonen; Lea Pylkkänen; Jukka-Pekka Mecklin; Heikki Järvinen; Jane S. Green; Jeremy R. Jass; James L. Weber; Fredrick S. Leach; Gloria M. Petersen; Stanley R. Hamilton; Albert de la Chapelle; Bert Vogelstein

Clues to the Pathogenesis of Familial Colorectal Cancer, pp. 812-816

Lauri A. Aaltonen; Päivi Peltomäki; Fredrick S. Leach; Pertti Sistonen; Lea Pylkkänen; Jukka-Pekka Mecklin; Heikki Järvinen; Steven M. Powell; Jin Jen; Stanley R. Hamilton; Gloria M. Petersen; Kenneth W. Kinzler; Bert Vogelstein; Albert de la Chapelle

Microsatellite Instability in Cancer of the Proximal Colon, pp. 816-819

S. N. Thibodeau; G. Bren; D. Schaid

Rapid Assessment of Drug Susceptibilities of Mycobacterium tuberculosis by Means of Luciferase Reporter Phages, pp. 819-822

William R. Jacobs, Jr.; Raúl G. Barletta; Rupa Udani; John Chan; Gary Kalkut; Gabriel Sosne; Tobias Kieser; Gary J. Sarkis; Graham F. Hatfull; Barry R. Bloom

Tyrosine Kinase-Stimulated Guanine Nucleotide Exchange Activity of Vav in T Cell Activation, pp. 822-825

Erich Gulbins; K. Mark Coggeshall; Gottfried Baier; Shulamit Katzav; Paul Burn; Amnon Altman

Technical Comment

Postglacial Offset Along the Seattle Fault, pp. 825-826

Robert M. Thorson

Book Reviews

Star Wars in Context, pp. 831-832

The Origins of SDI, 1944-1983.

Donald R. Baucom

Review author[s]: G. Allen Greb

A Disease in Resurgence, p. 832

Cholera.

Dhiman Barua; William B. Greenough III

Review author[s]: Stephen Richardson

Andean Imperialism, pp. 832-834

Provincial Power in the Inka Empire.

Terence N. D'Altroy

Review author[s]: Michael Malpass

Mechanisms of Learning, p. 834

Perceptual and Associative Learning.

Geoffrey Hall

Review author[s]: Thomas R. Zentall

Books Received, p. 834

Back Matter (30 pp.)

Previous Issue: New Series, Vol. 260, No. 5108, Apr. 30, 1993
Next Issue: New Series, Vol. 260, No. 5110, May 14, 1993

Science, New Series, Vol. 260, No. 5110, May 14, 1993

Previous Issue: New Series, Vol. 260, No. 5109, May 7, 1993
Next Issue: New Series, Vol. 260, No. 5111, May 21, 1993

Front Matter (35 pp.)
Editorial: The Human Cornucopia, p. 875

Barbara R. Jasny; Linda J. Miller

Letters

"MegaYAC" Library, p. 877

Glen A. Evans

Interdisciplinary Symposia, p. 877

Ben Zuckerman

Funding for Gene Therapy, pp. 877-878

Bruce A. Chabner; Ronald Levy

Biosphere 2: A New Kind of Science, pp. 878-879

Eugene P. Odum

Judging Science, p. 879

Jay A. Gold; Miles J. Zaremski; Elaine Rappaport Lev; Deborah H. Shefrin; Shanna H. Swan

Multidrug Resistance-Associated Protein: Sequence Correction, p. 879

Susan P. C. Cole; Roger G. Deeley

Knowing It All, p. 879

Ronald N. Bracewell

Corrections and Clarifications: Keystone's Blunt Message: 'It's the Virus Stupid', p. 879

Policy Forum

The Stalemate in Food and Agricultural Research, Teaching, and Extension, pp. 881+1007

James H. Meyer

ScienceScope, p. 883

Richard Stone

News and Comment

Measure for Measure in Science, pp. 884-886

Gary Taubes

Research Community Swats Grasshopper Control Trial, p. 887

Billy Goodman

Glossy Strategic Plan Hits the Streets, p. 888

Jon Cohen

Task Force: Level the Playing Field, pp. 888-889

Traci Watson

Yet Another Science Minister for Germany, p. 889

Peter Aldhous

Research News

How Ice Age Climate Got the Shakes, pp. 890-892

Richard A. Kerr

Old Feuds, New Finds Mark Anthropologists' Meeting, pp. 892-893

Elizabeth Culotta

The Remembrance of Blinks Past, p. 894

Marcia Barinaga

Botanical Witness for the Prosecution, pp. 894-895

Carol Kaesuk Yoon

Pons and Fleischmann Redux?, p. 895

Ivan Amato

Random Samples, pp. 896-897

Constance Holden

Frontiers in Biotechnology

News Reports

Biotech Gets a Grip on Cell Adhesion, pp. 906-908

John Travis

Biotech Sails Into Heavy Financial Seas, pp. 908-910

Richard Stone

Going Back to the Future With Small Synthetic Compounds, pp. 910-912

Anne Simon Moffat

Stand and Deliver: Getting Peptide Drugs Into the Body, pp. 912-913

Brigid M. Wallace; Jill S. Lasker

New Startups Move in As Gene Therapy Goes Commercial, pp. 914-915

Elizabeth Culotta

Perspectives

Molecular Advances in Cardiovascular Biology, pp. 916-917

Kenneth R. Chien

New Intracellular Targets for Therapeutic Drug Design, pp. 918-919

Joan S. Brugge

Tissue Engineering, pp. 920-926

Robert Langer; Joseph P. Vacanti

The Basic Science of Gene Therapy, pp. 926-932

Richard C. Mulligan

New Challenges in Human in Vitro Fertilization, pp. 932-936

Robert M. L. Winston; Alan H. Handyside

Identifying Strategies for Immune Intervention, pp. 937-944

Antonio Lanzavecchia

Research Article

Regulation of V(D)J Recombination Activator Protein RAG-2 by Phosphorylation, pp. 953-959

Weei-Chin Lin; Stephen Desiderio

Reports

Potassium Channels in Samanea saman Protoplasts Controlled by Phytochrome and the Biological Clock, pp. 960-962

Hak Yong Kim; Gary G. Coté; Richard C. Crain

A Large Drop in Atmospheric ¹⁴ C/ ¹² C and Reduced Melting in the Younger Dryas, Documented with ²³⁰ Th Ages of Corals, pp. 962-968

R. Lawrence Edwards; J. Warren Beck; G. S. Burr; D. J. Donahue; J. M. A. Chappell; A. L. Bloom; E. R. M. Druffel; F. W. Taylor

Beach Cusps as Self-Organized Patterns, pp. 968-971

B. T. Werner; T. M. Fink

Geography of End-Cretaceous Marine Bivalve Extinctions, pp. 971-973

David M. Raup; David Jablonski

Interaction of the San Jacinto and San Andreas Fault Zones, Southern California: Triggered Earthquake Migration and Coupled Recurrence Intervals, pp. 973-976

Christopher O. Sanders

Detection of HIV-1 DNA and Messenger RNA in Individual Cells by PCR-Driven in Situ Hybridization and Flow Cytometry, pp. 976-979

Bruce K. Patterson; Michele Till; Patricia Otto; Charles Goolsby; Manohar R. Furtado; Lincoln J. McBride; Steven M. Wolinsky

Crystal Structure of Domains 3 and 4 of Rat CD4: Relation to the NH₂-Terminal Domains, pp. 979-983

R. L. Brady; E. J. Dodson; G. G. Dodson; G. Lange; S. J. Davis; A. F. Williams; A. N. Barclay

Sequestration from Immune CD4⁺ T Cells of Mycobacteria Growing in Human Macrophages, pp. 984-986

Preeti Pancholi; Asra Mirza; Nina Bhardwaj; Ralph M. Steinman

CD19 of B Cells as a Surrogate Kinase Insert Region to Bind Phosphatidylinositol 3-Kinase, pp. 986-989

David A. Tuveson; Robert H. Carter; Stephen P. Soltoff; Douglas T. Fearon

Localization of a Memory Trace in the Mammalian Brain, pp. 989-991

David J. Krupa; Judith K. Thompson; Richard F. Thompson

Induction of Gα _i2 -Specific Antisense RNA in Vivo Inhibits Neonatal Growth, pp. 991-995

Christopher M. Moxham; Yaacov Hod; Craig C. Malbon

Cue-Invariant Shape Selectivity of Macaque Inferior Temporal Neurons, pp. 995-997

Gyula Sáry; Rufin Vogels; Guy A. Orban

Induction of Olfactory Receptor Sensitivity in Mice, pp. 998-1000

Hai-Wei Wang; Charles J. Wysocki; Geoffrey H. Gold

Book Reviews

Paycheck Equity, pp. 1008-1009

Comparable Worth. Theories and Evidence.

Paula England

Review author[s]: Joan Acker

Human Auxology, pp. 1009-1010

Growth, Maturation, and Body Composition. The Fels Longitudinal Study, 1929-1991.

Alex F. Roche

Review author[s]: Robert M. Malina

Looking at Crystals, pp. 1010-1011

Macromolecular Crystallography with Synchrotron Radiation.

John R. Helliwell

Review author[s]: Jenny P. Glusker

Anatomical Beginnings, p. 1011

Morphogenesis. An Analysis of the Development of Biological Form.

Edward F. Rossomando; Stephen Alexander

Review author[s]: Peter B. Armstrong

Books Received, pp. 1011-1012

Back Matter (32 pp.)

Previous Issue: New Series, Vol. 260, No. 5109, May 7, 1993
Next Issue: New Series, Vol. 260, No. 5111, May 21, 1993

Science, New Series, Vol. 260, No. 5111, May 21, 1993

Previous Issue: New Series, Vol. 260, No. 5110, May 14, 1993
Next Issue: New Series, Vol. 260, No. 5112, May 28, 1993

Front Matter (32 pp.)
Editorial: The Reader Response: Oyvey, p. 1055

Daniel E. Koshland, Jr.

Letters

NRC Report on DNA Typing, pp. 1057-1060

B. Delvin; Neil Risch; Kathryn Roeder; Ranajit Chakraborty

Interdisciplinary Communication, p. 1060

Darren Kocs

Evolutionary Relationships, p. 1060

Norman R. Pace

ScienceScope, p. 1063

Christopher Anderson

News and Comment

The Rocky Road to a Data Highway, pp. 1064-1065

Christopher Anderson

Virtual Libraries, Complete With Journals, Get Real, pp. 1066-1067

Larry Krumenaker

Healy Slams Clinton's NIH Budget, p. 1067

Christopher Anderson

An Expert Panel Advises, And the Army Consents, p. 1068

Eliot Marshall

Dental Institute Report Has NIH Down in the Mouth, p. 1069

Richard Stone

Random Samples, pp. 1070-1071

Constance Holden

Research News

Promising Protein for Parkinson's, pp. 1072-1073

Rick Weiss

Imanishi-Kari Says Her New Data Shows She Was Right, pp. 1073-1074

John Travis

A Faster Walk Along the Genome, p. 1075

Peter Aldhous

Computer Firms Look to the Brain, pp. 1075-1077

Toomas Koppel

Mass Calculations Add Weight to QCD, p. 1077

Robert Pool

Perspectives

Bound by Light, pp. 1078-1080

Mara G. Prentiss

A New Twist on Integrins and the Cytoskeleton, pp. 1080-1081

Steven R. Heidemann

Stratospheric Chlorine Injection by Volcanic Eruptions: HCl Scavenging and Implications for Ozone, pp. 1082-1086

A. Tabazadeh; R. P. Turco

On the Crawling of Animal Cells, pp. 1086-1094

Thomas P. Stossel

Reports

Deceleration of Interstellar Hydrogen at the Heliospheric Interface, pp. 1095-1098

Rosine Lallement; Jean-Loup Bertaux; John T. Clarke

Slow Magnetic Relaxation in Iron: A Ferromagnetic Liquid, pp. 1098-1101

R. V. Chamberlin; M. R. Scheinfein

South Asian Summer Monsoon Variability in a Model with Doubled Atmospheric Carbon Dioxide Concentration, pp. 1101-1104

Gerald A. Meehl; Warren M. Washington

A 3620-Year Temperature Record from Fitzroya cupressoides Tree Rings in Southern South America, pp. 1104-1106

Antonio Lara; Ricardo Villalba

Phenotypic Basis of Reproductive Success in a Social Insect: Genetic and Social Determinants, pp. 1107-1110

Laurent Keller; Kenneth G. Ross

Kinetics of Folding of the All-β Sheet Protein Interleukin-1β, pp. 1110-1113

Paul Varley; Angela M. Gronenborn; Henriette Christensen; Paul T. Wingfield; Roger H. Pain; G. Marius Clore

Substrate Phage: Selection of Protease Substrates by Monovalent Phage Display, pp. 1113-1117

David J. Matthews; James A. Wells

Structure of the Retinoid X Receptor α DNA Binding Domain: A Helix Required for Homodimeric DNA Binding, pp. 1117-1121

Min S. Lee; Steven A. Kliewer; Joan Provencal; Peter E. Wright; Ronald M. Evans

Generation of Allospecific Natural Killer Cells by Stimulation Across a Polymorphism of HLA-C, pp. 1121-1124

Marco Colonna; Edward G. Brooks; Michela Falco; Giovan Battista Ferrara; Jack L. Strominger

Mechanotransduction Across the Cell Surface and Through the Cytoskeleton, pp. 1124-1127

Ning Wang; James P. Butler; Donald E. Ingber

Expression of Pseudomonas aeruginosa Virulence Genes Requires Cell-to-Cell Communication, pp. 1127-1130

Luciano Passador; James M. Cook; Michael J. Gambello; Lynn Rust; Barbara H. Iglewski

GDNF: A Glial Cell Line-Derived Neurotrophic Factor for Midbrain Dopaminergic Neurons, pp. 1130-1132

Leu-Fen H. Lin; Daniel H. Doherty; Jack D. Lile; Susan Bektesh; Frank Collins

Structure and Functional Expression of a Member of the Low Voltage-Activated Calcium Channel Family, pp. 1133-1136

Tuck Wah Soong; Anthony Stea; Connie D. Hodson; Stefan J. Dubel; Steven R. Vincent; Terry P. Snutch

Book Reviews

Serious Thrills, pp. 1150-1152

William Frucht

Attention to Terms, pp. 1153-1154

Keywords in Evolutionary Biology.

Evelyn Fox Keller; Elisabeth A. Lloyd

Review author[s]: Douglas J. Futuyma

Biogenesis: Some Like It Hot, pp. 1154-1155

Marine Hydrothermal Systems and the Origin of Life. Report of SCOR Working Group 91.

N. G. Holm

Review author[s]: Antonio Lazcano

Heat Managers, pp. 1155-1156

The Hot-Blooded Insects. Strategies and Mechanisms of Thermoregulation.

Bernd Heinrich

Review author[s]: Albert F. Bennett

The Horse Tree, pp. 1156-1157

Fossil Horses. Systematics, Paleobiology, and Evolution of the Family Equidae.

Bruce J. MacFadden

Review author[s]: Malcolm C. McKenna

The Life Voyage, pp. 1157+1159

American Lives. Looking Back at the Children of the Great Depression.

John A. Clausen

Review author[s]: Naomi Gerstel

Social Gerontology, pp. 1160-1161

The Oldest Old.

Richard M. Suzman; David P. Willis; Kenneth G. Manton

Review author[s]: Christine E. Bishop

R & D Powerhouses, pp. 1161-1163

The Cold War and American Science. The Military-Industrial-Academic Complex at MIT and Stanford.

Stuart W. Leslie

Review author[s]: Daniel J. Kevles

Naturalist Administrator, pp. 1163-1164

Spencer Baird of the Smithsonian.

E. F. Rivinius; E. M. Youssef

Review author[s]: Jane Maienschein

Unpopularized Genius, pp. 1164-1165

John von Neumann.

Norman Macrae

Review author[s]: Paul E. Ceruzzi

Redefinitions in Physics, pp. 1165-1166

Out of the Crystal Maze. Chapters from the History of Solid-State Physics.

Lillian Hodeson; Ernest Braun; Jürgen Teichmann; Spencer Weart

Review author[s]: Yves Gingras

Technological Winners, pp. 1166+1168

The Evolution of Useful Things.

Henry Petroski

Review author[s]: Steven Lubar

Fixing Images, pp. 1168-1170

Out of the Shadows. Herschel, Talbot, and the Invention of Photography.

Larry J. Schaaf

Review author[s]: M. Susan Barger

Mathematical Structures, pp. 1170+1172-1173

Spatial Tessellations. Concepts and Applications of Voronoi Diagrams.

Atsuyuki Okabe; Barry Boots; Kokichi Sugihara

Review author[s]: Marjorie Senechal

Chaos Theory, p. 1173

The General Problem of the Stability of Motion.

A. M. Lyapunov

Nonlinearities in Action. Oscillations, Chaos, Order, Fractals.

A. V. Gaponov-Grekhov; M. I. Rabinovich

Review author[s]: Robert L. Devaney

All About Mars, pp. 1174-1175

Mars.

Hugh H. Kieffer; Bruce M. Jakosky; Conway W. Snyder; Mildred S. Matthews

Review author[s]: John F. Mustard

Messier 31, p. 1175

The Andromeda Galaxy.

Paul Hodge

Review author[s]: John Huchra

Southerly Enterprises, pp. 1175-1176

A History of Antarctic Science.

G. E. Fogg

Review author[s]: Eric L. Mills

The Human Scenario Beclouded, pp. 1176-1178

Evolutionary Ecology and Human Behavior.

Eric Alden Smith; Bruce Winter-Halder

Review author[s]: Henry Harpending

Speaking Remains, pp. 1178-1179

Bones. A Forensic Detective's Casebook.

Douglas Ubelaker; Henry Scammell

What the Bones Tell Us.

Jeffrey H. Schwartz

Review author[s]: Kenneth A. R. Kennedy

The Wages of Contact, pp. 1179-1180+1182

The Native Population of the Americas in 1492.

William M. Denevan

Disease and Demography in the Americas.

John W. Verano; Douglas H. Ubelaker

Disease, Depopulation, and Culture Change in Northwestern New Spain, 1518-1764.

Daniel T. Reff

Review author[s]: Marvin T. Smith

Mesoamerican Pantheon, p. 1182

The Gods and Symbols of Ancient Mexico and the Maya. An Illustrated Dictionary of Mesoamerican Religion.

Mary Miller; Karl Taube

Review author[s]: Stephen Houston

A Center in Peru, p. 1183

Chavín and the Origins of Andean Civilization.

Richard L. Burger

Review author[s]: Anne Paul

Exoticism Reconsidered, p. 1184

Anthropology and Photography, 1860-1920.

Elizabeth Edwards

Review author[s]: Douglas Harper

Inducements to Conflict, pp. 1184-1186

War in the Tribal Zone. Expanding States and Indigenous Warfare.

R. Brian Ferguson; Neil L. Whitehead

Review author[s]: Bruce M. Knauft

Books Reviewed in Science 15 May 1992 Through 14 May 1993, pp. 1186+1188+1190

Back Matter (18 pp.)

Previous Issue: New Series, Vol. 260, No. 5110, May 14, 1993
Next Issue: New Series, Vol. 260, No. 5112, May 28, 1993