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Previous Issue: New Series, Vol. 257, No. 5072, Aug. 14, 1992
Next Issue: New Series, Vol. 257, No. 5074, Aug. 28, 1992
Front Matter (14 pp.)
Editorial: The Microbial Wars, p. 1021
- Daniel E. Koshland, Jr.
Letters
- AIDS and the Polio Vaccine, pp. 1024+1026-1027
- Hilary Koprowski
- Fetal Tissue Banned...and Used, p. 1027
- Leonard Hayflick
- The Rowland Institute, p. 1027
- Richard C. Henry; Samantha H. Conrad; Gary W. Conrad; Ivan Amato
- Biological Motors, p. 1027
- Bruce Nicklas
ScienceScope, p. 1031
- David P. Hamilton
News and Comment
- `Mystery' Virus Meets the Skeptics, pp. 1032-1034
- Jon Cohen
- Massey Seeks to Broaden NSF's Role, p. 1035
- Joseph Palca
- Liability Bill Introduced in Congress, p. 1035
- Jon Cohen
- Exploring New Strategies to Fight Drug-Resistant Microbes, pp. 1036-1038
- Ann Gibbons
- Genetic Basis Found for Resistance to TB Drug, p. 1038
- Peter Aldhous
- National Science Board Sounds a Wake-Up Call, p. 1039
- David P. Hamilton
Research News
- Artificial Life's Rich Harvest, pp. 1040-1042
- M. Mitchell Waldrop
- War Over the Wetlands: Ecologists v. the White House, pp. 1043-1044
- Joseph Alper
- Physicists Rock the Standard Model in Dallas, pp. 1044-1045
- Faye Flam
- Knockout Mice Offer First Animal Model for CF, pp. 1046-1047
- Marcia Barinaga
Random Samples, pp. 1048-1049
- Richard Stone
Epidemiology of Drug Resistance: Implications for a Post-Antimicrobial Era, pp. 1050-1055
- Mitchell L. Cohen
Tuberculosis: Commentary on a Reemergent Killer, pp. 1055-1064
- Barry R. Bloom; Christopher J. L. Murray
The Crisis in Antibiotic Resistance, pp. 1064-1073
- Harold C. Neu
The Origin of Plagues: Old and New, pp. 1073-1078
- Richard M. Krause
Structure-Based Strategies for Drug Design and Discovery, pp. 1078-1082
- Irwin D. Kuntz
Research Articles
- An Animal Model for Cystic Fibrosis Made by Gene Targeting, pp. 1083-1088
- John N. Snouwaert; Kristen K. Brigman; Anne M. Latour; Nadia N. Malouf; Richard C. Boucher; Oliver Smithies; Beverly H. Koller
- Human and Drosophila Homeodomain Proteins That Enhance the DNA-Binding Activity of Serum Response Factor, pp. 1089-1095
- Dorre A. Grueneberg; Sridaran Natesan; Cyrille Alexandre; Michael Z. Gilman
Reports
- Mesosiderite Clasts with the Most Extreme Positive Europium Anomalies Among Solar System Rocks, pp. 1096-1099
- David W. Mittlefehldt; Alan E. Rubin; Andrew M. Davis
- Thermoelasticity of Silicate Perovskite and Magnesiowüstite and Stratification of the Earth's Mantle, pp. 1099-1101
- Lars Stixrude; R. J. Hemley; Y. Fei; H. K. Mao
- Microtektites and Mass Extinctions: Evidence for a Late Devonian Asteroid Impact, pp. 1102-1104
- Philippe Claeys; Jean-Georges Casier; Stanley V. Margolis
- Oxygen Isotope Constraints on the Origin of Impact Glasses from the Cretaceous-Tertiary Boundary, pp. 1104-1107
- Joel D. Blum; C. Page Chamberlain
- Scale and Structure in Natural Food Webs, pp. 1107-1109
- Karl Havens
- Trefoil Knotting Revealed by Molecular Dynamics Simulations of Supercoiled DNA, pp. 1110-1115
- Tamar Schlick; Wilma K. Olson
- A Mutation in the POU-Homeodomain of Pit-1 Responsible for Combined Pituitary Hormone Deficiency, pp. 1115-1118
- Sally Radovick; Michelle Nations; Yuefen Du; LaVonne A. Berg; Bruce D. Weintraub; Fredric E. Wondisford
- Mutation of the POU-Specific Domain of Pit-1 and Hypopituitarism Without Pituitary Hypoplasia, pp. 1118-1121
- R. W. Pfäffle; G. E. DiMattia; J. S. Parks; M. R. Brown; J. M. Wit; M. Jansen; H. Van der Nat; J. L. Van den Brande; M. G. Rosenfeld; H. A. Ingraham
- The Mouse Pink-Eyed Dilution Gene: Association with Human Prader-Willi and Angelman Syndromes, pp. 1121-1124
- John M. Gardner; Yoshimichi Nakatsu; Yoichi Gondo; Susan Lee; Mary F. Lyon; Richard A. King; Murray H. Brilliant
- Defective Epithelial Chloride Transport in a Gene-Targeted Mouse Model of Cystic Fibrosis, pp. 1125-1128
- Lane L. Clarke; Barbara R. Grubb; Sherif E. Gabriel; Oliver Smithies; Beverly H. Koller; Richard C. Boucher
- Mutations in the Rod Domains of Keratins 1 and 10 in Epidermolytic Hyperkeratosis, pp. 1128-1130
- J. A. Rothnagel; A. M. Dominey; L. D. Dempsey; M. A. Longley; D. A. Greenhalgh; T. A. Gagne; M. Huber; E. Frenk; D. Hohl; D. R. Roop
- Maintenance of in Vivo Tolerance by Persistence of Antigen, pp. 1130-1134
- Fred Ramsdell; B. J. Fowlkes
- Transactivation by AP-1 Is a Molecular Target of T Cell Clonal Anergy, pp. 1134-1138
- Sang-Mo Kang; Bart Beverly; Annie-Chen Tran; Kurt Brorson; Ronald H. Schwartz; Michael J. Lenardo
- A Truncated Erythropoietin Receptor That Fails to Prevent Programmed Cell Death of Erythroid Cells, pp. 1138-1141
- Yukio Nakamura; Norio Komatsu; Hiromitsu Nakauchi
Technical Comments
- Immunodominant T Cell Epitope from Signal Sequence, p. 1142
- Michael J. Buchmeier; Rolf M. Zinkernagel
- Plakoglobin and β-Catenin: Distinct But Closely Related, pp. 1142-1144
- Stefan Butz; Jörg Stappert; Helge Weissig; Rolf Kemler; P. D. McCrea; C. W. Turck; B. Gumbiner
Book Reviews
- The House That Jim Built, pp. 1145-1146
- Houses for Science. A Pictorial History of Cold Spring Harbor Laboratory.
- Elizabeth L. Watson
- Review author[s]: Joseph F. Sambrook
- Hopeful Meetings, p. 1146
- The Cybernetics Group.
- Steve Joshua Heims
- Review author[s]: Martin Shubik
- Neural Oscillations, pp. 1146-1148
- Suprachiasmatic Nucleus. The Mind's Clock.
- David C. Klein; Robert Y. Moore; Steven M. Reppert
- Review author[s]: Mary Harrington
- High-Energy Preoccupation, p. 1148
- The Structure of the Proton. Deep Inelastic Scattering.
- R. B. Roberts
- Review author[s]: Gabriel Karl
- Books Received, pp. 1148-1149
Back Matter (27 pp.)
Previous Issue: New Series, Vol. 257, No. 5072, Aug. 14, 1992
Next Issue: New Series, Vol. 257, No. 5074, Aug. 28, 1992