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Science, New Series, Vol. 256, No. 5058, May 8, 1992


Previous Issue: New Series, Vol. 256, No. 5057, May 1, 1992
Next Issue: New Series, Vol. 256, No. 5059, May 15, 1992


Front Matter (49 pp.)
Editorial: Molecular Advances in Diseases, p. 717
Daniel E. Koshland, Jr.


Letters
The Whitehead Institute and MIT, p. 719
Richard O. Hynes; Robert T. Sauer; Phillip A. Sharp
Out of Africa: Honey Bee Hybrids, pp. 719-721
Deborah R. Smith; T. E. Rinderer; B. P. Oldroyd; J. A. Stelzer; S. M. Buco; W. L. Rubink
Air Pollution and Mortality, p. 722
Frederick W. Lipfert; Samuel C. Morris


Corrections and Clarifications: A Mass Transfer Explanation of Metabolic Scaling Relations in Some Aquatic Invertebrates and Algae, p. 722
Mark R. Patterson

ScienceScope, p. 727
Richard Stone


News
Hard Times in the Promised Land, pp. 728-729
Richard Stone
Watkins Signals Retreat on DOE Directives, p. 729
Eliot Marshall
Yeast Chromosome III Reveals A Wealth of Unknown Genes, p. 730
Felix Eijgenraam
Are Neutrino Mass Hunters Pursuing a Chimera?, pp. 731-733
Gary Taubes
Ozone Hole: Not Over the Arctic-for Now, p. 734
Richard A. Kerr
Press Urges Doubling for Research, p. 734
Richard Stone


`Verdicts' Are in on the Gallo Probe, pp. 735-738
Joseph Palca

Scientist-Consultants Accuse OSI of Missing the Pattern, pp. 738-739
David P. Hamilton

Random Samples, pp. 740-741
Constance Holden


Molecular Advances


Biotech Special Report
Biotech's Second Generation, pp. 766-768
Ann Gibbons
Massachusetts Woos Biotech Investment, pp. 768-769
Michelle Hoffman
High-Tech Plants Promise a Bumper Crop of New Products, pp. 770-771
Anne Simon Moffat
Animal Models Point the Way to Human Clinical Trials, pp. 772-773
Rebecca Kolberg

Cystic Fibrosis: Molecular Biology and Therapeutic Implications, pp. 774-779
Francis S. Collins
Alzheimer's Disease: A Cell Biological Perspective, pp. 780-783
Kenneth S. Kosik
Triplet Repeat Mutations in Human Disease, pp. 784-789
C. Thomas Caskey; Antonio Pizzuti; Ying-Hui Fu; Raymond G. Fenwick Jr.; David L. Nelson
Malignant Hyperthermia, pp. 789-794
David H. MacLennan; Michael S. Phillips
Gaucher Disease: New Molecular Approaches to Diagnosis and Treatment, pp. 794-799
Ernest Beutler
Molecular Genetics of Epidermolysis Bullosa, pp. 799-804
Ervin H. Epstein, Jr.
On the Molecular Genetics of Retinitis Pigmentosa, pp. 804-808
Peter Humphries; Paul Kenna; G. Jane Farrar
Human Gene Therapy, pp. 808-813
W. French Anderson


Perspective
Crystal Polarity: A Window on Ice Nucleation, p. 814
J. Michael McBride


Reports
The Role of Crystal Polarity in α-Amino Acid Crystals for Induced Nucleation of Ice, pp. 815-818
M. Gavish; J.-L. Wang; M. Eisenstein; M. Lahav; L. Leiserowitz
Metallo-Carbohedrenes: Formation of Multicage Structures, pp. 818-820
S. Wei; B. C. Guo; J. Purnell; S. Buzza; A. W. Castleman, Jr.
UV Spectrum and Proposed Role of Diethylberyllium in a 7Li-7 Be Solar Neutrino Experiment, pp. 820-822
P. Dyer
Synthesis and Single-Crystal X-ray Structure of a Highly Symmetrical C 60 Derivative, C 60 Br 24, pp. 822-825
Fred N. Tebbe; Richard L. Harlow; D. Bruce Chase; David L. Thorn; G. Creston Campbell, Jr.; Joseph C. Calabrese; Norman Herron; Robert J. Young, Jr.; E. Wasserman
Implication of GAP in Ras-Dependent Transactivation of a Polyoma Enhancer Sequence, pp. 825-827
Fabien Schweighoffer; Isabelle Barlat; Marie-Christine Chevallier-Multon; Bruno Tocque
Oncogenic Forms of p53 Inhibit p53-Regulated Gene Expression, pp. 827-830
Scott E. Kern; Jennifer A. Pietenpol; Sam Thiagalingam; Albert Seymour; Kenneth W. Kinzler; Bert Vogelstein
Cholecystokinin Antianalgesia: Safety Cues Abolish Morphine Analgesia, pp. 830-833
Eric P. Wiertelak; Steven F. Maier; Linda R. Watkins
Changes in the Sensory Processing of Olfactory Signals Induced by Birth in Sheep, pp. 833-836
K. M. Kendrick; F. Lévy; E. B. Keverne
Initiation of Deregulated Growth of Multipotent Progenitor Cells by bcr-abl in Vitro, pp. 836-839
Mikhail L. Gishizky; Owen N. Witte
Primary Structure and Functional Expression of the β1 Subunit of the Rat Brain Sodium Channel, pp. 839-842
L. L. Isom; K. S. De Jongh; D. E. Patton; B. F. X. Reber; J. Offord; H. Charbonneau; K. Walsh; A. L. Goldin; W. A. Catterall
Recovery from Experimental Parkinsonism in Primates with G M1 Ganglioside Treatment, pp. 843-846
J. S. Schneider; Anne Pope; Kimberly Simpson; James Taggart; M. G. Smith; L. DiStefano
Lateralization of Phonetic and Pitch Discrimination in Speech Processing, pp. 846-849
Robert J. Zatorre; Alan C. Evans; Ernst Meyer; Albert Gjedde


Technical Comments
Neocortex Development and the Cell Cycle, pp. 849-850
Derek van der Kooy; Susan K. McConnell; Christine E. Kaznowski


Book Reviews
A Standpoint on Science, pp. 863-864
Whose Science? Whose Knowledge? Thinking from Women's Lives.
Sandra Harding
Review author[s]: Rayna Rapp
An Enthusiasm in Cosmology, pp. 864-865
Quantum Cosmology and Baby Universes.
S. Coleman; J. B. Hartle; T. Piran; S. Weinberg
Review author[s]: Don N. Page
Biological Restoration, p. 865
A History of Regeneration Research. Milestones in the Evolution of a Science.
Charles E. Dinsmore
Review author[s]: Karen Crawford
Books Received, pp. 865-866


Back Matter (70 pp.)

Previous Issue: New Series, Vol. 256, No. 5057, May 1, 1992
Next Issue: New Series, Vol. 256, No. 5059, May 15, 1992



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