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Science, New Series, Vol. 254, No. 5029, Genome Issue: Maps and Database, Oct. 11, 1991


Previous Issue: New Series, Vol. 254, No. 5028, Special Issue: Instrumentation, Oct. 4, 1991
Next Issue: New Series, Vol. 254, No. 5030, Oct. 18, 1991


Front Matter (43 pp.)
Flying Into The Future, p. 173
Daniel E. Koshland, Jr.


Letters
Population Diversity and the Future of Ecosystems, p. 175
Paul R. Ehrlich
The Need for Mandatory Retirement for Tenured Faculty, pp. 175-176
Saunders Mac Lane; Albert Rees; Sharon P. Smith; Leo Gross
Research on Animals: Unforseen Benefits, p. 176
Adrian R. Morrison


ScienceScope, p. 183
David P. Hamilton


News and Comment
Genome Patent Fight Erupts, pp. 184-186
Leslie Roberts
Edelman: Bye, Bye Rockefeller, p. 186
Ann Gibbons
A Window on Life In the Bronze Age, pp. 187-188
Felix Eijenraam; Alun Anderson
JAMA Gets Into an Indian Herbal Jam, pp. 188-189
Robert Barnett; Cathy Sears
Leroy Hood to Move North, p. 189
David P. Hamilton
Malaria Parasite Gaining Ground Against Science, p. 190
Eliot Marshall
Space Station, NSF Funds Approved, p. 191
Eliot Marshall


Briefings
NAS Forms Environment Panel, p. 192
Constance Holden
Resurrected Lead, p. 192
Constance Holden
Sugar Sours Future for Gum Arabic, p. 192
Constance Holden
Pauling Institute Foundering, pp. 192-193
Constance Holden
Draper Awards for WWII Foes, p. 193
Constance Holden
Name Games at DOE, p. 193
Constance Holden
Fusion Panel Lowers Its Sights, p. 193
Constance Holden
More Sorry Math News, p. 193
Constance Holden


Research News
The SSC: Radical Therapy for Physics, pp. 194-196
Faye Flam
CERN's Horserace With the SSC, p. 195
David P. Hamilton
What Makes the San Andreas Tick?, pp. 197-198
Richard A. Kerr
Improvements Seen for RU-486 Abortions, pp. 198+200
John Maurice
Feminist Group Dissents on RU-486 Use for Abortion, p. 199
Michelle Hoffman
Alcoholism Gene: Coming or Going?, p. 200
Constance Holden
Genome Databases, pp. 201-207


Perspective
The Human Genome Initiative-Do Databases Reflect Current Progress?, pp. 214-215
P. L. Pearson; B. Maidak; M. Chipperfield; R. Robbins


Toward Cloning and Mapping the Genome of Drosophila, pp. 221-225
J. Merriam; M. Ashburner; D. L. Hartl; F. C. Kafatos

On the Social Science Contribution to Governmental Decision-Making, pp. 226-231
Eleanor Chelimsky

Reactivity of Organic Compounds in Hot Water: Geochemical and Technological Implications, pp. 231-237
Michael Siskin; Alan R. Katritzky


Research Article
Role of Nucleosomal Cores and Histone H1 in Regulation of Transcription by RNA Polymerase II, pp. 238-245
Paul J. Laybourn; James T. Kadonaga


Genome Maps 1991, pp. 247-262
David Rosin; Michael Chipperfield; Bonnie Maidak; Peter Pearson; Michael Ashburner; David M. Glover; Robert D. C. Saunders; Ian Duncan; Daniel Hartl; John Merriam; Geunbae Lee; Joy Johnsen; Fotis C. Kafatos; Inga Sidén-Kiamos; Christos Louis; Charalambos Savakis


Reports
A Mantle Plume Initiation Model for the Wrangellia Flood Basalt and Other Oceanic Plateaus, pp. 263-267
Mark A. Richards; David L. Jones; Robert A. Duncan; Donald J. DePaolo
The DNA Binding Arm of λ Repressor: Critical Contacts from a Flexible Region, pp. 267-270
Neil D. Clarke; Lesa J. Beamer; Harry R. Goldberg; Carol Berkower; Carol O. Pabo
Structure and Stability of X·G·C Mismatches in the Third Strand of Intramolecular Triplexes, pp. 270-274
Román F. Macaya; Dara E. Gilbert; Shiva Malek; Janet S. Sinsheimer; Juli Feigon
A Retroviral Oncogene, akt, Encoding a Serine-Threonine Kinase Containing an SH2-Like Region, pp. 274-277
Alfonso Bellacosa; Joseph R. Testa; Stephen P. Staal; Philip N. Tsichlis
Defining Protective Responses to Pathogens: Cytokine Profiles in Leprosy Lesions, pp. 277-279
Masahiro Yamamura; Koichi Uyemura; Robert J. Deans; Kenneth Weinberg; Thomas H. Rea; Barry R. Bloom; Robert L. Modlin
Differing Lymphokine Profiles of Functional Subsets of Human CD4 and CD8 T Cell Clones, pp. 279-282
Padmini Salgame; John S. Abrams; Carol Clayberger; Harris Goldstein; Jacinto Convit; Robert L. Modlin; Barry R. Bloom
Cell Cycle Dependence of Laminar Determination in Developing Neocortex, pp. 282-285
Susan K. McConnell; Christine E. Kaznowski
Long-Term High-Titer Neutralizing Activity Induced by Octameric Synthetic HIV-1 Antigen, pp. 285-288
C. Y. Wang; D. J. Looney; M. L. Li; A. M. Walfield; J. Ye; B. Hosein; J. P. Tam; F. Wong-Staal
Modulation of the Time Course of Fast EPSCs and Glutamate Channel Kinetics by Aniracetam, pp. 288-290
Cha-Min Tang; Qing-Yao Shi; Alex Katchman; Gary Lynch
Laser Ablation Studies of the Role of the Drosophila Oocyte Nucleus in Pattern Formation, pp. 290-293
Denise J. Montell; Haig Keshishian; Allan C. Spradling
Suppression of Tumorigenicity in Wilms Tumor by the p15.5-p14 Region of Chromosome 11, pp. 293-295
Steven F. Dowdy; Clare L. Fasching; Diana Araujo; Kin-Man Lai; Elizabeth Livanos; Bernard E. Weissman; Eric J. Stanbridge


Book Reviews
Voices Heard in Museums, pp. 311-312
Exhibiting Cultures. The Poetics and Politics of Museum Display.
Ivan Karp; Steven D. Lavine
Review author[s]: Burton Benedict
Uniquely Human, pp. 313-314
The Lopsided Ape. Evolution of the Generative Mind.
Michael C. Corballis
Review author[s]: Lauren Julius Harris
The Landsat Case, p. 314
Viewing the Earth. The Social Construction of the Landsat Satellite System.
Pamela E. Mack
Review author[s]: Karl Hufbauer
Physics in Canada, pp. 314-315
Physics and the Rise of Scientific Research in Canada.
Yves Gingras
Review author[s]: Albert E. Moyer
Books Received, p. 315


Back Matter (29 pp.)

Previous Issue: New Series, Vol. 254, No. 5028, Special Issue: Instrumentation, Oct. 4, 1991
Next Issue: New Series, Vol. 254, No. 5030, Oct. 18, 1991



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