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Science, New Series, Vol. 251, No. 4998, Mar. 8, 1991


Previous Issue: New Series, Vol. 251, No. 4997, Mar. 1, 1991
Next Issue: New Series, Vol. 251, No. 4999, Mar. 15, 1991


Front Matter (19 pp.)
Science Puts Its Best Foot Forward, p. 1157
Daniel E. Koshland, Jr.


Policy Forum
Curing the Orphan Drug Act, pp. 1158-1159
Jess G. Thoene


Letters
Effectiveness of AIDS Vaccines, p. 1161
Albert B. Sabin
"Sequence-Gazing?", pp. 1161-1162
Jon Beckwith; Mark A. Poritz; Harris D. Bernstein; Peter Walter
Unus et Triginta Quoque Anno?, p. 1162
Garrett Hardin
Steroid Therapy Publication Delay, p. 1162
Paul Meier
Buckyballs and Double Bonds, p. 1162
Harold Hart
GABAergic Pathway from Zona Incerta to Neocortex: Clarification, p. 1162
Chia-Sheng Lin; Miguel A. L. Nicolelis; Jay S. Schneider; John K. Chapin, Jr.


Erratum: "Nuclear Winter" from Gulf War Discounted, p. 1162
ScienceScope, p. 1167
David P. Hamilton


News and Comment
Verdict in Sight in the "Baltimore Case", pp. 1168-1172
David P. Hamilton
Putting AIDS Research in Perspective, p. 1172
Joseph Palca
Early Detection Nips Math Problems in the Bud, pp. 1173-1174
Anne Simon Moffat
And the Winner: Cetus Does Own PCR, p. 1174
Marcia Barinaga
Kuwait's Unjust Deserts: Damage to Its Desert, p. 1175
Constance Holden


Research News
Dimers Direct Development, pp. 1176-1177
Marcia Barinaga
The Florida Panther Verges on Extinction, pp. 1178-1180
Chuck Fergus
New Clue Found to Growth Factor Action, p. 1181
Michelle Hoffman
El Niño Winners and Losers Declared, p. 1182
Richard A. Kerr
Costs of a Clean Environment, p. 1182
Leslie Roberts


Briefings
Animal Rules Final, p. 1183
Constance Holden
Pauling at 90, p. 1183
Constance Holden
Bomb Detectors: OTA Thumbs Down, p. 1183
Constance Holden
Biotech: Rx for a Healthy Future, p. 1183
Constance Holden


Perspective
Bureaucratic Mischief: Recognizing Endangered Species and Subspecies, pp. 1187-1188
Stephen J. O'Brien; Ernst Mayr


The Current Situation in Mexican Immigration, pp. 1189-1193
Georges Vernez; David Ronfeldt

The Quark-Hadron Transition in Cosmology and Astrophysics, pp. 1194-1199
K. A. Olive

Diabetic Hyperglycemia: Link to Impaired Glucose Transport in Pancreatic β Cells, pp. 1200-1205
Roger H. Unger


Research Articles
Manipulation of Adsorbed Atoms and Creation of New Structures on Room-Temperature Surfaces with a Scanning Tunneling Microscope, pp. 1206-1210
L. J. Whitman; Joseph A. Stroscio; R. A. Dragoset; R. J. Celotta
Max: A Helix-Loop-Helix Zipper Protein That Forms a Sequence-Specific DNA-Binding Complex with Myc, pp. 1211-1217
Elizabeth M. Blackwood; Robert N. Eisenman


Reports
Auger Electron Angular Distributions from Surfaces: Direct Comparison with Isoenergetic Photoelectrons, pp. 1218-1220
Louis J. Terminello; John J. Barton
Evidence for an Inter-Organismic Heme Biosynthetic Pathway in Symbiotic Soybean Root Nodules, pp. 1220-1222
Indu Sangwan; Mark R. O'Brian
Induction of Self-Tolerance in T Cells But Not B Cells of Transgenic Mice Expressing Little Self Antigen, pp. 1223-1225
Stephen Adelstein; Helen Pritchard-Briscoe; Tracy A. Anderson; Jeffrey Crosbie; Guy Gammon; Robert H. Loblay; Antony Basten; Christopher C. Goodnow
Peripheral Selection of the T Cell Repertoire, pp. 1225-1228
Benedita Rocha; Harald von Boehmer
Split Anergy in a CD8+ T Cell: Receptor-Dependent Cytolysis in the Absence of Interleukin-2 Production, pp. 1228-1231
Gillis R. Otten; Ronald N. Germain
Regulation of Phospholipase C-γl by Profilin and Tyrosine Phosphorylation, pp. 1231-1233
Pascal J. Goldschmidt-Clermont; Jae Won Kim; Laura M. Machesky; Sue Goo Rhee; Thomas D. Pollard
Enhanced Motility in NIH 3T3 Fibroblasts That Overexpress Gelsolin, pp. 1233-1236
C. Casey Cunningham; Thomas P. Stossel; David J. Kwiatkowski
Isolation of Sequences That Span the Fragile X and Identification of a Fragile X-Related CpG Island, pp. 1236-1239
D. Heitz; F. Rousseau; D. Devys; S. Saccone; H. Abderrahim; D. Le Paslier; D. Cohen; A. Vincent; D. Toniolo; G. Della Valle; S. Johnson; D. Schlessinger; I. Oberle; J. L. Mandel
Subtle Cerebellar Phenotype in Mice Homozygous for a Targeted Deletion of the En-2 Homeobox, pp. 1239-1243
A. L. Joyner; K. Herrup; B. A. Auerbach; C. A. Davis; J. Rossant
Control of Larval Development by Chemosensory Neurons in Caenorhabditis elegans, pp. 1243-1246
Cornelia I. Bargmann; H. Robert Horvitz
Failure to Elicit Neuronal Macroscopic Mechanosensitive Currents Anticipated by Single-Channel Studies, pp. 1246-1249
Catherine E. Morris; Richard Horn
Paths of Information Flow Through Visual Cortex, pp. 1249-1251
Marc Mignard; Joseph G. Malpeli
The Role of the Primate Extrastriate Area V4 in Vision, pp. 1251-1253
Peter H. Schiller; Kyoungmin Lee


Book Reviews
Atomic Energy: The View from France, p. 1257
Atomic Rivals.
Bertrand Goldschmidt
Review author[s]: Lawrence Scheinman
The Career of a Methodology, p. 1258
Ratio Scaling of Psychological Magnitude. In Honor of the Memory of S. S. Stevens.
Stanley J. Bolanowski, Jr.; George A. Gescheider
Review author[s]: Robert Teghtsoonian
Before and After Phage, pp. 1258-1259
The Emergence of Bacterial Genetics.
Thomas D. Brock
Review author[s]: Jeffrey H. Miller
Reprints of Books Previously Reviewed, p. 1259
Books Received, p. 1259


Back Matter (21 pp.)

Previous Issue: New Series, Vol. 251, No. 4997, Mar. 1, 1991
Next Issue: New Series, Vol. 251, No. 4999, Mar. 15, 1991



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